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DE3787927D1 - Small peptides that inhibit binding to T-4 receptors and act as immunogens. - Google Patents

Small peptides that inhibit binding to T-4 receptors and act as immunogens.

Info

Publication number
DE3787927D1
DE3787927D1 DE87304939T DE3787927T DE3787927D1 DE 3787927 D1 DE3787927 D1 DE 3787927D1 DE 87304939 T DE87304939 T DE 87304939T DE 3787927 T DE3787927 T DE 3787927T DE 3787927 D1 DE3787927 D1 DE 3787927D1
Authority
DE
Germany
Prior art keywords
immunogens
receptors
act
inhibit binding
small peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE87304939T
Other languages
German (de)
Other versions
DE3787927T2 (en
Inventor
Candace B Pert
Michael R Ruff
William L Farrar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United States Department of Commerce
Original Assignee
United States Department of Commerce
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by United States Department of Commerce filed Critical United States Department of Commerce
Application granted granted Critical
Publication of DE3787927D1 publication Critical patent/DE3787927D1/en
Publication of DE3787927T2 publication Critical patent/DE3787927T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70514CD4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • AIDS & HIV (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE87304939T 1986-06-03 1987-06-03 Small peptides that inhibit binding to T-4 receptors and act as immunogens. Expired - Fee Related DE3787927T2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86991986A 1986-06-03 1986-06-03
US87858686A 1986-06-26 1986-06-26
US4814887A 1987-05-11 1987-05-11

Publications (2)

Publication Number Publication Date
DE3787927D1 true DE3787927D1 (en) 1993-12-02
DE3787927T2 DE3787927T2 (en) 1994-03-03

Family

ID=27367286

Family Applications (1)

Application Number Title Priority Date Filing Date
DE87304939T Expired - Fee Related DE3787927T2 (en) 1986-06-03 1987-06-03 Small peptides that inhibit binding to T-4 receptors and act as immunogens.

Country Status (16)

Country Link
JP (1) JP2680011B2 (en)
KR (1) KR930008448B1 (en)
AU (1) AU604719B2 (en)
CA (1) CA1341066C (en)
DE (1) DE3787927T2 (en)
DK (1) DK173667B1 (en)
ES (1) ES2061497T3 (en)
FI (1) FI94352C (en)
HU (1) HUT48907A (en)
IE (1) IE61725B1 (en)
IL (1) IL82719A (en)
MX (1) MX172337B (en)
NO (1) NO176022C (en)
NZ (1) NZ220485A (en)
PT (1) PT84992B (en)
WO (1) WO1987007613A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0611927A2 (en) * 2005-06-23 2011-08-16 Rapid Pharmaceuticals Ag therapeutic compositions
CN101088557A (en) 2006-06-12 2007-12-19 天津市扶素生物技术有限公司 Medicine composition for preventing and treating HIV infection and its application

Also Published As

Publication number Publication date
NZ220485A (en) 1989-08-29
NO880479L (en) 1988-02-03
NO176022B (en) 1994-10-10
DK173667B1 (en) 2001-05-28
AU7540887A (en) 1988-01-11
AU604719B2 (en) 1991-01-03
FI885630A0 (en) 1988-12-02
WO1987007613A1 (en) 1987-12-17
PT84992A (en) 1987-07-01
ES2061497T3 (en) 1994-12-16
MX172337B (en) 1993-12-14
JPH01502659A (en) 1989-09-14
IL82719A (en) 1992-11-15
DE3787927T2 (en) 1994-03-03
HUT48907A (en) 1989-07-28
DK53288A (en) 1988-02-02
FI885630A (en) 1988-12-02
FI94352C (en) 1995-08-25
DK53288D0 (en) 1988-02-02
CA1341066C (en) 2000-08-01
JP2680011B2 (en) 1997-11-19
PT84992B (en) 1990-03-08
KR930008448B1 (en) 1993-09-04
IL82719A0 (en) 1987-11-30
NO880479D0 (en) 1988-02-03
FI94352B (en) 1995-05-15
NO176022C (en) 1995-01-18
KR880701247A (en) 1988-07-26
IE61725B1 (en) 1994-11-30
IE871388L (en) 1987-12-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee