DE3785994D1 - Antikoerper gegen interleukin-1. - Google Patents

Antikoerper gegen interleukin-1.

Info

Publication number: DE3785994D1
Authority: DE; Germany
Prior art keywords: antibody against; against interleukin; interleukin; antibody
Prior art date: 1986-11-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE8787116724T

Other languages

English (en)

Other versions

DE3785994T2 (de

Inventor

Yasukazu - Ohmoto

Kenji - Nagamura

Hisakazu Aoki

Yoshikatsu - Hirai

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Otsuka Pharmaceutical Co Ltd

Original Assignee

Otsuka Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-11-13

Filing date

1987-11-12

Publication date

1993-07-01

1987-11-12 Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd

1993-07-01 Publication of DE3785994D1 publication Critical patent/DE3785994D1/de

1993-11-11 Application granted granted Critical

1993-11-11 Publication of DE3785994T2 publication Critical patent/DE3785994T2/de

2007-11-13 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/245—IL-1
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Biophysics (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Cell Biology (AREA)
General Engineering & Computer Science (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DE87116724T 1986-11-13 1987-11-12 Antikörper gegen Interleukin-1. Expired - Fee Related DE3785994T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP27099286		1986-11-13

Publications (2)

Publication Number	Publication Date
DE3785994D1 true DE3785994D1 (de)	1993-07-01
DE3785994T2 DE3785994T2 (de)	1993-11-11

Family

ID=17493888

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE87116724T Expired - Fee Related DE3785994T2 (de)	1986-11-13	1987-11-12	Antikörper gegen Interleukin-1.

Country Status (5)

Country	Link
EP (1)	EP0267611B1 (de)
KR (1)	KR900004420B1 (de)
DE (1)	DE3785994T2 (de)
DK (1)	DK590387A (de)
ES (1)	ES2054644T3 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5998578A (en) *	1984-05-18	1999-12-07	New England Medical Center Hospitals, Inc.	Biologically active fragments of IL-1β
EP0569687B1 (de) *	1984-05-18	2002-08-21	New England Medical Center Hospitals, Inc.	Menschliche IL-1 cDNS-Sequenzen die für biologisch aktive menschliche IL-1-Proteine kodieren
JPH0681599B2 (ja) *	1988-10-01	1994-10-19	大塚製薬株式会社	インターロイキン―１βに対する抗体
DE68925935T2 (de) *	1988-10-01	1996-08-14	Otsuka Pharma Co Ltd	Antikörper gegen Interleukin-1-beta
FR2640146B1 (fr) *	1988-12-08	1993-12-24	Commissariat A Energie Atomique	Anticorps monoclonaux anti-interleukines 1(alpha) et 1(beta), leur procede de production et applications desdits anticorps a la detection des interleukines 1(alpha) et 1(beta) et en therapeutique
DK195089A (da) *	1989-04-20	1990-10-21	Morten Bagge Hansen	Regulatoriske proteiner
WO1991008774A1 (en) *	1989-12-15	1991-06-27	Cetus Corporation	Cytokine antibody for the treatment of sepsis
WO1995001997A1 (en) *	1993-07-09	1995-01-19	Smithkline Beecham Corporation	RECOMBINANT AND HUMANIZED IL-1β ANTIBODIES FOR TREATMENT OF IL-1 MEDIATED INFLAMMATORY DISORDERS IN MAN
EP0659766A1 (de) *	1993-11-23	1995-06-28	Schering-Plough	Menschliche Monoklonalantikörper gegen menschliche Cytokine und Verfahren zur Herstellung dieser Antikörper
US5959085A (en) *	1993-11-23	1999-09-28	Schering Corporation	Human monoclonal antibodies against human cytokines and methods of making and using such antibodies
DE4408890A1 (de) *	1994-03-16	1995-09-21	Knoll Ag	Verwendung von Il-1-Antagonisten als Arzneimittel zur Behandlung von Erkrankungen mit einem erhöhten Interleukin-6 Serumspiegel
EP0813423B1 (de) *	1995-01-23	2002-07-03	Xenotech Incorporated	Zusammensetzung zur verhinderung von osteolyse und metastasen
AU3116697A (en) *	1996-05-20	1997-12-09	Schering Corporation	Human interleukin-1j and antagonists thereof
EP2002846B1 (de)	1996-12-06	2017-01-25	Amgen Inc.	Kombinationstherapie mit einem IL-1-Inhibitor zur Behandlung von IL-1-vermittelten Krankheiten
US6808902B1 (en)	1999-11-12	2004-10-26	Amgen Inc.	Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
GB0020685D0 (en) *	2000-08-22	2000-10-11	Novartis Ag	Organic compounds
PT2087908T (pt)	2001-06-26	2018-07-16	Amgen Inc	Anticorpos contra opgl
EA033750B1 (ru)	2002-09-06	2019-11-21	Amgen Inc	Изолированная молекула нуклеиновой кислоты, кодирующая антитело человека к рецептору интерлейкина-1, и ее применение
WO2004060911A2 (en)	2002-12-30	2004-07-22	Amgen Inc.	Combination therapy with co-stimulatory factors
US7566772B2 (en)	2005-01-26	2009-07-28	Amgen Fremont Inc.	Antibodies against interleukin-1β
SI2163562T1 (sl)	2005-06-21	2014-01-31	Xoma (Us) Llc	IL-1 beta vezavna protitelesa in njihovi fragmenti
ATE470151T1 (de)	2005-08-02	2010-06-15	Xbiotech Inc	Diagnose, behandlung und prävention von gefässerkrankungen mittels il-1alpha- autoantikörpern
PE20070684A1 (es)	2005-11-14	2007-08-06	Amgen Inc	MOLECULAS QUIMERICAS DE ANTICUERPO RANKL-PTH/PTHrP
JP5645409B2 (ja)	2006-12-20	2014-12-24	ゾーマ（ユーエス）リミテッドライアビリティカンパニー	ＩＬ−１β関連疾患の治療方法
PL2391650T3 (pl)	2007-12-20	2015-03-31	Xoma Us Llc	Sposoby leczenia dny
JP5670318B2 (ja)	2008-05-30	2015-02-18	エックスバイオテク, インコーポレイテッドXbiotech, Inc.	インターロイキン１α抗体及び有用な方法
WO2010028275A1 (en)	2008-09-05	2010-03-11	Xoma Technology Ltd.	METHODS FOR TREATING OR PREVENTING IL-1ß RELATED DISEASES
CN102209557A (zh)	2008-09-12	2011-10-05	埃克斯生物科技公司	靶向病原性单核细胞
JP5904645B2 (ja)	2010-05-07	2016-04-13	ゾーマ（ユーエス）リミテッドライアビリティカンパニー	ＩＬ−１β関連病態の治療のための方法
EP2582391B1 (de)	2010-06-18	2018-10-03	XBiotech, Inc	Arthritis-behandlung
KR20210128021A (ko)	2010-08-23	2021-10-25	얀센 바이오테크 인코포레이티드	종양성 질병들에 대한 치료
US9724409B2 (en)	2011-04-01	2017-08-08	Xbiotech, Inc.	Treatment of inflammatory skin disease
PT2750709T (pt)	2011-09-23	2018-11-22	Xbiotech Inc	Tratamento da caquexia
CN104144946A (zh)	2011-12-19	2014-11-12	爱克索马美国有限责任公司	治疗痤疮的方法
US9545441B2 (en)	2012-09-18	2017-01-17	Xbiotech, Inc.	Treatment of diabetes
AU2018220862A1 (en)	2017-02-16	2019-08-29	Janssen Biotech, Inc.	Treatment of hidradenitis suppurativa
WO2020035482A1 (en)	2018-08-13	2020-02-20	Iltoo Pharma	Combination of interleukin-2 with an interleukin 1 inhibitor, conjugates and therapeutic uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK172052B1 (da) *	1984-12-21	1997-09-29	Otsuka Pharma Co Ltd	Antitumor-aktivt stof, fremgangsmåde til dets fremstilling, lægemiddel indeholdende stoffet, gen kodende for stoffet, vektor indeholdende genet samt rekombinant mikroorganisme transformet med en sådan vektor
DE3587605T2 (de) *	1984-12-25	1994-03-17	Dainippon Pharmaceutical Co	Interleukin-1 und dessen Derivat.
JPS6291197A (ja) *	1985-10-17	1987-04-25	Dainippon Pharmaceut Co Ltd	抗ヒトインタ−ロイキン１抗体，その製法及びその使用法

1987
- 1987-11-11 DK DK590387A patent/DK590387A/da not_active Application Discontinuation
- 1987-11-12 DE DE87116724T patent/DE3785994T2/de not_active Expired - Fee Related
- 1987-11-12 ES ES87116724T patent/ES2054644T3/es not_active Expired - Lifetime
- 1987-11-12 EP EP87116724A patent/EP0267611B1/de not_active Expired - Lifetime
- 1987-11-13 KR KR1019870012791A patent/KR900004420B1/ko not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK590387D0 (da)	1987-11-11
EP0267611B1 (de)	1993-05-26
KR880006357A (ko)	1988-07-22
DE3785994T2 (de)	1993-11-11
EP0267611A3 (en)	1988-09-21
ES2054644T3 (es)	1994-08-16
DK590387A (da)	1988-05-14
EP0267611A2 (de)	1988-05-18
KR900004420B1 (ko)	1990-06-25

Publication	Publication Date	Title
DE3785994D1 (de)	1993-07-01	Antikoerper gegen interleukin-1.
DE3777594D1 (de)	1992-04-23	Mikroskop.
DE68916667D1 (de)	1994-08-18	Mikroskop.
ATE70057T1 (de)	1991-12-15	Antitumormittel.
DE3767169D1 (de)	1991-02-14	Sportschuh.
ATE57924T1 (de)	1990-11-15	3-aryloxy-3-substituierte-propanamine.
FI875115A0 (fi)	1987-11-19	Bryggningstekniker foer lokala naet.
FI875744L (fi)	1988-07-01	Polykarbofil innehaollande aemneskomposition.
FI893691A0 (fi)	1989-08-04	Ny injektionsspruta.
DE3879452D1 (de)	1993-04-22	Chimaere antikoerper.
FI873581A0 (fi)	1987-08-19	Fast stoedanordning.
FI905812A0 (fi)	1990-11-26	Interleukin-1 inhibitorer.
FI890088L (fi)	1989-07-09	Termostatisk blandningsventil.
FI874493A0 (fi)	1987-10-12	Ljusstraolningsanordning foer medicinskt bruk.
FI880486A0 (fi)	1988-02-03	Ventil foer ersaettningsluft.
FI893422A0 (fi)	1989-07-14	Madrasskonstruktion foer vattenbaedd.
FI890087L (fi)	1989-07-09	Termostatisk blandningsventil.
DE3763648D1 (de)	1990-08-16	Rollski.
NO874520D0 (no)	1987-10-30	Undertakskonstruksjon.
IT8723186A0 (it)	1987-12-23	Incannatrice.
DE3763205D1 (de)	1990-07-19	Nahtbuegelplatz.
DE3669032D1 (de)	1990-03-22	Okulopressionsgeraet.
FI875300A0 (fi)	1987-12-01	Azolderivat.
FI860188L (fi)	1987-07-16	Skidvalla.
FI893344L (fi)	1990-01-13	Konstruktionsfaeste.

Legal Events

Date	Code	Title	Description
1994-06-30	8364	No opposition during term of opposition
2000-02-10	8339	Ceased/non-payment of the annual fee