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DE3777575D1 - 2-dithioalkyl-dihydropyridine, verfahren zu ihrer herstellung und pharmazeutische zusammenstellungen, die sie enthalten. - Google Patents

2-dithioalkyl-dihydropyridine, verfahren zu ihrer herstellung und pharmazeutische zusammenstellungen, die sie enthalten.

Info

Publication number
DE3777575D1
DE3777575D1 DE8787119081T DE3777575T DE3777575D1 DE 3777575 D1 DE3777575 D1 DE 3777575D1 DE 8787119081 T DE8787119081 T DE 8787119081T DE 3777575 T DE3777575 T DE 3777575T DE 3777575 D1 DE3777575 D1 DE 3777575D1
Authority
DE
Germany
Prior art keywords
groups
dithioalkyl
dihydropyridine
contain
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787119081T
Other languages
English (en)
Inventor
Marco Frigerio
Carmelo A Gandolfi
Sergio Tognella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics SpA
Original Assignee
Roche Diagnostics SpA
Boehringer Mannheim Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics SpA, Boehringer Mannheim Italia SpA filed Critical Roche Diagnostics SpA
Application granted granted Critical
Publication of DE3777575D1 publication Critical patent/DE3777575D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE8787119081T 1986-12-24 1987-12-22 2-dithioalkyl-dihydropyridine, verfahren zu ihrer herstellung und pharmazeutische zusammenstellungen, die sie enthalten. Expired - Lifetime DE3777575D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8622881A IT1213440B (it) 1986-12-24 1986-12-24 2-ditioalchil-diidropiridine, un metodo per la loro preparazione e composizioni farmaceutiche chele contengono.

Publications (1)

Publication Number Publication Date
DE3777575D1 true DE3777575D1 (de) 1992-04-23

Family

ID=11201500

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787119081T Expired - Lifetime DE3777575D1 (de) 1986-12-24 1987-12-22 2-dithioalkyl-dihydropyridine, verfahren zu ihrer herstellung und pharmazeutische zusammenstellungen, die sie enthalten.

Country Status (7)

Country Link
US (1) US4956369A (de)
EP (1) EP0272694B1 (de)
JP (1) JPS63170361A (de)
AT (1) ATE73775T1 (de)
CA (1) CA1313526C (de)
DE (1) DE3777575D1 (de)
IT (1) IT1213440B (de)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284634A (en) * 1975-07-02 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 1,4-Dihydropyridine derivatives, and pharmaceutical method of the same
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
IL68604A0 (en) * 1982-05-21 1983-09-30 Haessle Ab Processes for preparing therapeutically active dihydropyridines and intermediates for the processes
US4690935A (en) * 1983-03-31 1987-09-01 Wayne State University Inhibition of tumor growth and metastasis with calcium channel blocker compounds
EP0169009A3 (de) * 1984-07-17 1988-08-31 FISONS plc Dihydropyridinderivate und ihre Herstellung, Formulierung und Verwendung als Pharmazeutika
EP0200524A3 (de) * 1985-05-03 1987-06-16 Pfizer Limited Dihydropyridin-Calcium-Antagonisten

Also Published As

Publication number Publication date
JPS63170361A (ja) 1988-07-14
US4956369A (en) 1990-09-11
ATE73775T1 (de) 1992-04-15
EP0272694A1 (de) 1988-06-29
IT8622881A0 (it) 1986-12-24
EP0272694B1 (de) 1992-03-18
IT1213440B (it) 1989-12-20
CA1313526C (en) 1993-02-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee