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DE3775754D1 - Alpha-halogenierte dicarbonsaeuren enthaltende pharmazeutische zusammensetzungen. - Google Patents

Alpha-halogenierte dicarbonsaeuren enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
DE3775754D1
DE3775754D1 DE8787308939T DE3775754T DE3775754D1 DE 3775754 D1 DE3775754 D1 DE 3775754D1 DE 8787308939 T DE8787308939 T DE 8787308939T DE 3775754 T DE3775754 T DE 3775754T DE 3775754 D1 DE3775754 D1 DE 3775754D1
Authority
DE
Germany
Prior art keywords
alpha
halogened
pharmaceutical compositions
acids containing
containing pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787308939T
Other languages
English (en)
Inventor
Jacob Bar-Tana
Yoelit Migron
Jochanan Blum
Bruno Dreckman
Johannes Pill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Epis SA
Original Assignee
Epis SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epis SA filed Critical Epis SA
Priority to DE8787308939T priority Critical patent/DE3775754D1/de
Application granted granted Critical
Publication of DE3775754D1 publication Critical patent/DE3775754D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02—Dicarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02—Dicarboxylic acids
    • C07C55/21—Dicarboxylic acids containing twelve carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/32—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms containing halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8787308939T 1986-10-08 1987-10-08 Alpha-halogenierte dicarbonsaeuren enthaltende pharmazeutische zusammensetzungen. Expired - Fee Related DE3775754D1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE8787308939T DE3775754D1 (de) 1986-10-08 1987-10-08 Alpha-halogenierte dicarbonsaeuren enthaltende pharmazeutische zusammensetzungen.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863634356 DE3634356A1 (de) 1986-10-08 1986-10-08 Arzneimittel enthaltend alpha-halogenierte dicarbonsaeuren
DE8787308939T DE3775754D1 (de) 1986-10-08 1987-10-08 Alpha-halogenierte dicarbonsaeuren enthaltende pharmazeutische zusammensetzungen.

Publications (1)

Publication Number Publication Date
DE3775754D1 true DE3775754D1 (de) 1992-02-13

Family

ID=6311352

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19863634356 Withdrawn DE3634356A1 (de) 1986-10-08 1986-10-08 Arzneimittel enthaltend alpha-halogenierte dicarbonsaeuren
DE8787308939T Expired - Fee Related DE3775754D1 (de) 1986-10-08 1987-10-08 Alpha-halogenierte dicarbonsaeuren enthaltende pharmazeutische zusammensetzungen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19863634356 Withdrawn DE3634356A1 (de) 1986-10-08 1986-10-08 Arzneimittel enthaltend alpha-halogenierte dicarbonsaeuren

Country Status (18)

Country Link
US (1) US4908385A (de)
EP (1) EP0279978B1 (de)
JP (1) JP2583545B2 (de)
KR (1) KR960003807B1 (de)
AU (1) AU603613B2 (de)
CA (1) CA1311243C (de)
DD (1) DD269145A5 (de)
DE (2) DE3634356A1 (de)
DK (1) DK298588A (de)
ES (1) ES2037725T3 (de)
FI (1) FI90860C (de)
GR (1) GR3003697T3 (de)
HU (1) HU199385B (de)
IE (1) IE60236B1 (de)
IL (1) IL84107A (de)
PT (1) PT85882B (de)
WO (1) WO1988002746A1 (de)
ZA (1) ZA877444B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5214198A (en) * 1991-12-20 1993-05-25 American Cyanamid Company Process for the manufacture of halomaleic and halofumaric esters
US5602164A (en) * 1992-04-28 1997-02-11 Senyorina Ltd. Anti-obesity drugs
DE4224670A1 (de) * 1992-07-25 1994-01-27 Boehringer Mannheim Gmbh Verwendung von â,w-Dicarbonsäuren als Fibrinogensenker
DE4439947A1 (de) * 1994-11-09 1996-05-15 Boehringer Mannheim Gmbh 2,2-Dichloralkancarbonsäuren, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
IL119971A (en) * 1997-01-07 2003-02-12 Yissum Res Dev Co Pharmaceutical compositions containing dicarboxylic acids and derivatives thereof and some novel dicarboxylic acids
US6692918B2 (en) * 1999-09-13 2004-02-17 Nugen Technologies, Inc. Methods and compositions for linear isothermal amplification of polynucleotide sequences
DK1431303T3 (en) 1999-09-13 2014-02-17 Nugen Technologies Inc A composition for isothermal linear amplification of polynucleotide sequences
MXPA02012735A (es) 2000-06-26 2004-04-20 Nugen Tgechnologies Inc Metodos y composiciones para la amplificacion de acido nucleico a base de transcripcion.
US7846733B2 (en) 2000-06-26 2010-12-07 Nugen Technologies, Inc. Methods and compositions for transcription-based nucleic acid amplification
US6858413B2 (en) 2000-12-13 2005-02-22 Nugen Technologies, Inc. Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof
KR20030082535A (ko) 2001-03-09 2003-10-22 뉴젠 테크놀로지스 인코포레이티드 Ｒｎａ 서열의 증폭을 위한 방법 및 조성물
CA2439074A1 (en) 2001-03-09 2002-09-19 Nugen Technologies, Inc. Methods and compositions for amplification of rna sequences
EP1613778B1 (de) 2003-04-14 2014-11-26 Nugen Technologies, Inc. Globale amplifizierung unter verwendung von zufallsgeprimeten zusammen gesetzten primern
CA2621267A1 (en) 2005-09-07 2007-03-15 Nugen Technologies, Inc. Improved nucleic acid amplification procedure
US8034568B2 (en) 2008-02-12 2011-10-11 Nugen Technologies, Inc. Isothermal nucleic acid amplification methods and compositions
WO2009117698A2 (en) 2008-03-21 2009-09-24 Nugen Technologies, Inc. Methods of rna amplification in the presence of dna
EP2787986B1 (de) 2011-12-08 2017-10-18 Syndromex Ltd. Deuterierte tetramethyldionsäuren, zusammensetzungen damit und verwendungen davon

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2971915A (en) * 1957-02-11 1961-02-14 Shell Oil Co Lubricating oil compositions
US3678102A (en) * 1970-09-11 1972-07-18 Ugine Kuhlmann {60 ,{60 ,{60 {40 ,{60 {40 -tetrasubstituted carboxylic diacids and process for their preparation
GB1350611A (en) * 1971-07-15 1974-04-18 Bp Chem Int Ltd Production of tetramethyl suberic acid
IL64542A0 (en) * 1981-12-15 1982-03-31 Yissum Res Dev Co Long-chain alpha,omega-dicarboxylic acids and derivatives thereof and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JPH01501549A (ja) 1989-06-01
IL84107A (en) 1992-09-06
DK298588D0 (da) 1988-06-01
KR960003807B1 (ko) 1996-03-22
PT85882B (pt) 1990-07-31
GR3003697T3 (de) 1993-03-16
IL84107A0 (en) 1988-03-31
FI882669L (fi) 1988-06-06
HU199385B (en) 1990-02-28
AU603613B2 (en) 1990-11-22
DK298588A (da) 1988-06-01
JP2583545B2 (ja) 1997-02-19
IE872679L (en) 1988-04-08
IE60236B1 (en) 1994-06-15
HUT46645A (en) 1988-11-28
CA1311243C (en) 1992-12-08
WO1988002746A1 (en) 1988-04-21
US4908385A (en) 1990-03-13
AU8027787A (en) 1988-05-06
EP0279978A1 (de) 1988-08-31
EP0279978B1 (de) 1992-01-02
ES2037725T3 (es) 1993-07-01
FI882669A0 (fi) 1988-06-06
ZA877444B (en) 1989-01-25
KR880701700A (ko) 1988-11-04
PT85882A (de) 1987-11-01
FI90860C (fi) 1994-04-11
DD269145A5 (de) 1989-06-21
DE3634356A1 (de) 1988-04-21
FI90860B (fi) 1993-12-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee