DE3752338D1 - Anti-Sense-Regulierung von Genexpression in Pflanzenzellen - Google Patents
Anti-Sense-Regulierung von Genexpression in PflanzenzellenInfo
- Publication number
- DE3752338D1 DE3752338D1 DE3752338T DE3752338T DE3752338D1 DE 3752338 D1 DE3752338 D1 DE 3752338D1 DE 3752338 T DE3752338 T DE 3752338T DE 3752338 T DE3752338 T DE 3752338T DE 3752338 D1 DE3752338 D1 DE 3752338D1
- Authority
- DE
- Germany
- Prior art keywords
- gene expression
- plant cells
- sense regulation
- regulation
- sense
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
- 230000000692 anti-sense effect Effects 0.000 title 1
- 230000014493 regulation of gene expression Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01015—Polygalacturonase (3.2.1.15)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US84567686A | 1986-03-28 | 1986-03-28 | |
US92057486A | 1986-10-17 | 1986-10-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3752338D1 true DE3752338D1 (de) | 2001-11-22 |
DE3752338T2 DE3752338T2 (de) | 2002-06-27 |
Family
ID=27126594
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3752338T Revoked DE3752338T2 (de) | 1986-03-28 | 1987-03-19 | Anti-Sense-Regulierung von Genexpression in Pflanzenzellen |
DE3750755T Expired - Lifetime DE3750755T2 (de) | 1986-03-28 | 1987-03-19 | Anti-sense-Regulierung von Genexpression in Pflanzenzellen. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3750755T Expired - Lifetime DE3750755T2 (de) | 1986-03-28 | 1987-03-19 | Anti-sense-Regulierung von Genexpression in Pflanzenzellen. |
Country Status (12)
Country | Link |
---|---|
EP (2) | EP0458367B1 (de) |
JP (3) | JP2702921B2 (de) |
CN (1) | CN87102348A (de) |
AR (1) | AR241938A1 (de) |
AT (2) | ATE114168T1 (de) |
AU (3) | AU618234B2 (de) |
CA (2) | CA1341579C (de) |
DE (2) | DE3752338T2 (de) |
ES (2) | ES2165348T3 (de) |
GR (1) | GR3015085T3 (de) |
IL (1) | IL81737A (de) |
NZ (1) | NZ219472A (de) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6617496B1 (en) * | 1985-10-16 | 2003-09-09 | Monsanto Company | Effecting virus resistance in plants through the use of negative strand RNAs |
DE3751393T2 (de) * | 1986-04-02 | 1996-02-22 | Pioneer Hi Bred Int | Pflanzen, resistent gegen den Anti-sens RNS aufweisenden Virus. |
EP0323473A4 (de) * | 1986-08-26 | 1990-02-21 | Univ Macquarie | Transformation eines mikroorganismus unter verwendung von antisens-rns oder der promotor-okklusionstechnik. |
GB8626879D0 (en) * | 1986-11-11 | 1986-12-10 | Ici Plc | Dna |
NZ224787A (en) * | 1987-05-26 | 1990-08-28 | Calgene Inc | A dna construct for specifically modifying the phenotype of fruit as distinct from other plant tissue |
GB8811115D0 (en) * | 1988-05-11 | 1988-06-15 | Ici Plc | Tomatoes |
US6255564B1 (en) | 1988-02-03 | 2001-07-03 | Paladin Hybrids, Inc. | Molecular methods of hybrid seed production |
NZ227835A (en) * | 1988-02-03 | 1992-09-25 | Paladin Hybrids Inc | Antisense gene systems of pollination control for hybrid seed production |
WO1990008828A2 (en) * | 1989-02-02 | 1990-08-09 | Paladin Hybrids Inc. | Molecular methods of hybrid seed production |
US5356799A (en) * | 1988-02-03 | 1994-10-18 | Pioneer Hi-Bred International, Inc. | Antisense gene systems of pollination control for hybrid seed production |
US6737560B1 (en) | 1988-02-03 | 2004-05-18 | Pioneer Hi-Bred International, Inc. | Molecular methods of hybrid seed production |
US5728926A (en) * | 1988-02-03 | 1998-03-17 | Pioneer Hi-Bred International, Inc. | Antisense gene systems of pollination control for hybrid seed production |
NL8800756A (nl) * | 1988-03-25 | 1989-10-16 | Vereniging Voor Christelijk Wetenschappelijk Onderwijs | Genetisch gemanipuleerde plantecellen en planten, alsmede daarvoor bruikbaar recombinant dna. |
DE3810286A1 (de) * | 1988-03-25 | 1989-10-12 | Max Planck Gesellschaft | Transgene pflanze mit modifizierter physiologie, morphologie und modifiziertem hormonmetabolismus, gewebekulturen dieser pflanze und verfahren zu ihrer herstellung |
GB8818706D0 (en) * | 1988-08-05 | 1988-09-07 | Ici Plc | Dna constructs & plants incorporating them |
WO1990002172A1 (en) * | 1988-08-18 | 1990-03-08 | Calgene, Inc. | Plant elongation factor, promoters, coding sequences and uses |
GB8916213D0 (en) * | 1989-07-14 | 1989-08-31 | Ici Plc | Dna constructs,cells and plants derived therefrom |
US5744364A (en) * | 1989-10-20 | 1998-04-28 | Zeneca Limited | PTOM36 constructs and tomato cells transformed therewith |
GB8923716D0 (en) * | 1989-10-20 | 1989-12-06 | Ici Plc | Dna,constructs,cells and plants derived therefrom |
AU644619B2 (en) * | 1989-12-21 | 1993-12-16 | Advanced Technologies (Cambridge) Limited | Modification of plant metabolism |
FR2658988A1 (fr) * | 1990-03-02 | 1991-09-06 | Biosem | Betterave resistante a la rhizomanie. |
ATE129745T1 (de) * | 1990-03-02 | 1995-11-15 | Biocem | Regenerierung und genetische transformation der zuckerrübe. |
US5585545A (en) * | 1990-04-20 | 1996-12-17 | The Regents Of The University Of California | Endo-1,4-β-glucanase genes and their use in plants |
US5168064A (en) * | 1990-04-20 | 1992-12-01 | The Regents Of The University Of California | Endo-1,4-β-glucanase gene and its use in plants |
GB9009307D0 (en) * | 1990-04-25 | 1990-06-20 | Ici Plc | Dna,constructs,cells and plant derived therefrom |
US5260205A (en) * | 1990-11-14 | 1993-11-09 | Philip Morris Incorporated | Method of purifying putrescine N-methyltransferase from tobacco plant extract with a polyamine |
US5668295A (en) * | 1990-11-14 | 1997-09-16 | Philip Morris Incorporated | Protein involved in nicotine synthesis, DNA encoding, and use of sense and antisense DNAs corresponding thereto to affect nicotine content in transgenic tobacco cells and plants |
US5750862A (en) * | 1990-11-29 | 1998-05-12 | The Australian National University | Control of plant cell proliferation and growth |
CA2098837A1 (en) * | 1990-12-21 | 1992-06-22 | Colin Brady | Dna sequences encoding at least part of the tomato enzyme endopolygalacturonase pg1 .beta.-subunit |
NZ241311A (en) * | 1991-01-17 | 1995-03-28 | Gen Hospital Corp | Rna sequence having trans-splicing activity, plant strains |
NZ314629A (en) * | 1991-01-17 | 2000-08-25 | Gen Hospital Corp | Use trans-splicing ribozymes to prepare medicaments for gene therapies |
GB9109063D0 (en) * | 1991-04-26 | 1991-06-12 | Ici Plc | Modification of lignin synthesis in plants |
GB9112645D0 (en) * | 1991-06-12 | 1991-07-31 | Cambridge Advanced Tech | Modification of starch production |
AU2778992A (en) * | 1991-10-07 | 1993-05-03 | Idaho Research Foundation Inc., The | Genetic construct for selection of homologous recombinants on a single selective medium |
WO1993018643A1 (en) * | 1992-03-24 | 1993-09-30 | Rice Breeding Research Laboratories | Process for reducing seed storage proteins and process for transforming plants |
US5516694A (en) * | 1992-03-26 | 1996-05-14 | Takara Shuzo Co., Ltd. | Endo-xyloglucan transferase |
JP2898499B2 (ja) * | 1992-03-26 | 1999-06-02 | 寳酒造株式会社 | エンド型キシログルカン転移酵素遺伝子 |
EP0606454A1 (de) * | 1992-07-30 | 1994-07-20 | Keygene N.V. | Dna konstruktionen, zellen und die davon abgeleiteten pflanzen |
WO1994005795A1 (en) * | 1992-08-27 | 1994-03-17 | Commonwealth Scientific And Industrial Research Organisation | Dna sequences encoding peach polygalacturonase |
WO1994010320A1 (en) * | 1992-11-02 | 1994-05-11 | Mogen International N.V. | Plants with reduced susceptibility to plant-parasitic nematodes |
GB9405768D0 (en) * | 1994-03-23 | 1994-05-11 | Univ Leicester | Viral replicon |
US6013859A (en) * | 1994-07-14 | 2000-01-11 | Pioneer Hi-Bred International, Inc. | Molecular methods of hybrid seed production |
US6448474B1 (en) | 1995-06-07 | 2002-09-10 | University Of Hawaii | Purified proteins, recombinant DNA sequences and processes for controlling the ripening of coffee plants |
US6010904A (en) * | 1995-06-07 | 2000-01-04 | The General Hospital Corporation | Cell ablation using trans-splicing ribozymes |
GB9514435D0 (en) * | 1995-07-14 | 1995-09-13 | Danisco | Inhibition of gene expression |
GB9525353D0 (en) | 1995-12-12 | 1996-02-14 | Nat Starch Chem Invest | Potato soluble starch synthase |
US6075184A (en) * | 1996-03-26 | 2000-06-13 | University Of Hawaii | Purified proteins, recombinant DNA sequences and processes for producing caffeine free beverages |
CN1248292A (zh) * | 1997-02-21 | 2000-03-22 | 丹尼斯科有限公司 | 淀粉分支酶表达的反义内含子的抑制作用 |
WO1998042848A1 (en) * | 1997-03-24 | 1998-10-01 | University Of Hawaii | Purified proteins, recombinant dna sequences and processes for producing caffeine free beverages |
US6586661B1 (en) | 1997-06-12 | 2003-07-01 | North Carolina State University | Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid |
AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
CN101818145A (zh) | 1998-03-20 | 2010-09-01 | 联邦科学和工业研究组织 | 控制基因表达 |
US8598332B1 (en) | 1998-04-08 | 2013-12-03 | Bayer Cropscience N.V. | Methods and means for obtaining modified phenotypes |
WO1999053050A1 (en) | 1998-04-08 | 1999-10-21 | Commonwealth Scientific And Industrial Research Organisation | Methods and means for obtaining modified phenotypes |
US20040214330A1 (en) | 1999-04-07 | 2004-10-28 | Waterhouse Peter Michael | Methods and means for obtaining modified phenotypes |
US7019195B1 (en) | 1998-05-26 | 2006-03-28 | Syngenta Participations Ag | Method for conferring resistance or tolerance aganist furovirus, potyvirus, tospovirus, and cucomovirus to plant cells |
AR020078A1 (es) * | 1998-05-26 | 2002-04-10 | Syngenta Participations Ag | Metodo para alterar la expresion de un gen objetivo en una celula de planta |
GB9827152D0 (en) | 1998-07-03 | 1999-02-03 | Devgen Nv | Characterisation of gene function using double stranded rna inhibition |
DE19836098A1 (de) * | 1998-07-31 | 2000-02-03 | Hoechst Schering Agrevo Gmbh | Pflanzen, die eine modifizierte Stärke synthetisieren, Verfahren zur Herstellung der Pflanzen, ihre Verwendung sowie die modifizierte Stärke |
US7148400B1 (en) | 1999-04-20 | 2006-12-12 | Bayer Bioscience N.V. | Methods and means for delivering inhibitory RNA to plants and applications thereof |
US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
HUP0302320A3 (en) * | 2000-06-23 | 2005-11-28 | Pioneer Hi Bred Int | Recombinant constructs and their use in reducing gene expression |
JP2004507250A (ja) | 2000-08-30 | 2004-03-11 | ノース・キャロライナ・ステイト・ユニヴァーシティ | タンパク質含量を変化させる分子デコイを含有するトランスジェニック植物 |
ATE360701T1 (de) | 2000-11-07 | 2007-05-15 | Univ North Carolina State | Putrescin-n-methyltransferasepromotor |
EP1331845B1 (de) | 2000-11-09 | 2012-01-04 | Commonwealth Scientific And Industrial Research Organisation | Gerste mit reduzierter ssii-aktivität und stärkehaltige produkte mit reduziertem amylopectingehalt |
HUP0400161A2 (hu) | 2001-06-08 | 2004-08-30 | Vector Tobacco Ltd., | Módosított nikotin- és nitrozamintartalmú dohány |
CN1646687A (zh) | 2002-03-14 | 2005-07-27 | 联邦科学和工业研究组织 | 修饰的基因沉默rna及其用途 |
DE10212892A1 (de) | 2002-03-20 | 2003-10-09 | Basf Plant Science Gmbh | Konstrukte und Verfahren zur Regulation der Genexpression |
EP2290084A3 (de) | 2003-06-30 | 2011-10-12 | Commonwealth Scientific and Industrial Research Organization | Weizen mit veränderter Verzweigungsenzymaktivität und daraus abgeleitete Stärke-haltige Produkte |
WO2006069422A1 (en) | 2004-12-30 | 2006-07-06 | Commonwealth Scientific And Industrial Research Organisation | Method and means for improving bowel health |
NZ598048A (en) | 2006-01-17 | 2013-05-31 | Synthon Biopharmaceuticals Bv | Compositions and methods for humanization and optimization of n-glycans in plants |
US9315818B2 (en) | 2006-06-07 | 2016-04-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Plant expression constructs and methods of utilizing same |
CN101952445A (zh) | 2007-12-21 | 2011-01-19 | 关键基因公司 | 毛状体特异性启动子 |
EP2100962A1 (de) | 2008-03-12 | 2009-09-16 | Biogemma | Pflanzen mit verbesserter Widerstandsfähigkeit gegen Pathogene |
ES2879599T3 (es) | 2009-06-08 | 2021-11-22 | Nunhems Bv | Plantas tolerantes a la sequía |
NL2004624C2 (en) | 2010-04-28 | 2011-11-01 | Stichting Dienst Landbouwkundi | A new glycosyltransferase protein and its role in the metabolism of phenylpropanoid volatiles in tomato. |
WO2011147968A1 (en) | 2010-05-28 | 2011-12-01 | Nunhems B.V. | Plants with increased fruit size |
NL2014107B1 (en) | 2015-01-09 | 2016-09-29 | Limgroup B V | New methods and products for breeding of asparagus. |
JP6978152B2 (ja) | 2015-09-04 | 2021-12-08 | キージーン ナムローゼ フェンノートシャップ | 複相胞子生殖遺伝子 |
US11066681B2 (en) | 2016-08-26 | 2021-07-20 | Lesaffre Et Compagnie | Production of itaconic acid |
EP3533878A1 (de) | 2018-02-28 | 2019-09-04 | Dutch DNA Biotech B.V. | Verfahren zur herstellung von 2-hydroxy-2-methylbutandisäure unter verwendung von aspergillus |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4771002A (en) * | 1984-02-24 | 1988-09-13 | Lubrizol Genetics, Inc. | Transcription in plants and bacteria |
EP1213348A2 (de) * | 1985-03-21 | 2002-06-12 | Johnston, Stephen, Ph.D. | Vom Parasit abgeleiteter Widerstand |
US6617496B1 (en) * | 1985-10-16 | 2003-09-09 | Monsanto Company | Effecting virus resistance in plants through the use of negative strand RNAs |
US6608241B1 (en) * | 1985-10-29 | 2003-08-19 | Monsanto Technology Llc | Protection of plants against viral infection |
DE3751393T2 (de) * | 1986-04-02 | 1996-02-22 | Pioneer Hi Bred Int | Pflanzen, resistent gegen den Anti-sens RNS aufweisenden Virus. |
JPH02502513A (ja) * | 1986-07-25 | 1990-08-16 | ザ ボード オブ スーパーバイザーズ オブ ルイジアナ ステート ユニバーシティ アンド アグリカルチュラル アンド メカニカル カレッジ | 病気抵抗体及び害虫抵抗体を植物に組み込む方法並びに植物に組み込まれ該抵抗体の暗号に対応する新規な遺伝子 |
EP0323473A4 (de) * | 1986-08-26 | 1990-02-21 | Univ Macquarie | Transformation eines mikroorganismus unter verwendung von antisens-rns oder der promotor-okklusionstechnik. |
AU7918387A (en) * | 1986-08-26 | 1988-03-24 | Macquarie University | Transformation of an organism using antisense rna or promoter occlusion technique |
GB8626879D0 (en) * | 1986-11-11 | 1986-12-10 | Ici Plc | Dna |
-
1987
- 1987-03-03 IL IL81737A patent/IL81737A/xx not_active IP Right Cessation
- 1987-03-03 NZ NZ219472A patent/NZ219472A/xx unknown
- 1987-03-18 CN CN87102348A patent/CN87102348A/zh active Pending
- 1987-03-19 EP EP91109006A patent/EP0458367B1/de not_active Revoked
- 1987-03-19 ES ES91109006T patent/ES2165348T3/es not_active Expired - Lifetime
- 1987-03-19 DE DE3752338T patent/DE3752338T2/de not_active Revoked
- 1987-03-19 ES ES87302367T patent/ES2066759T3/es not_active Expired - Lifetime
- 1987-03-19 AT AT87302367T patent/ATE114168T1/de not_active IP Right Cessation
- 1987-03-19 DE DE3750755T patent/DE3750755T2/de not_active Expired - Lifetime
- 1987-03-19 EP EP87302367A patent/EP0240208B1/de not_active Expired - Lifetime
- 1987-03-19 AT AT91109006T patent/ATE207125T1/de not_active IP Right Cessation
- 1987-03-25 AU AU70597/87A patent/AU618234B2/en not_active Withdrawn - After Issue
- 1987-03-27 CA CA000533209A patent/CA1341579C/en active Active
- 1987-03-27 AR AR87307141A patent/AR241938A1/es active
- 1987-03-27 JP JP62071918A patent/JP2702921B2/ja not_active Expired - Lifetime
- 1987-03-27 CA CA000617172A patent/CA1341601C/en active Active
-
1992
- 1992-03-19 AU AU13017/92A patent/AU1301792A/en not_active Abandoned
-
1993
- 1993-08-06 AU AU44470/93A patent/AU4447093A/en not_active Abandoned
-
1995
- 1995-02-16 GR GR950400303T patent/GR3015085T3/el unknown
-
1997
- 1997-05-13 JP JP9122043A patent/JPH1052283A/ja active Pending
-
1999
- 1999-06-23 JP JP17737299A patent/JP3670889B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NZ219472A (en) | 1990-08-28 |
ATE207125T1 (de) | 2001-11-15 |
ES2066759T3 (es) | 1995-03-16 |
CA1341579C (en) | 2008-07-29 |
AU4447093A (en) | 1993-12-09 |
AR241938A1 (es) | 1993-01-29 |
EP0240208B1 (de) | 1994-11-17 |
EP0240208A2 (de) | 1987-10-07 |
DE3750755T2 (de) | 1995-05-18 |
DE3752338T2 (de) | 2002-06-27 |
AU7059787A (en) | 1987-10-01 |
JPH1052283A (ja) | 1998-02-24 |
GR3015085T3 (en) | 1995-05-31 |
JP2702921B2 (ja) | 1998-01-26 |
AU618234B2 (en) | 1991-12-19 |
EP0458367B1 (de) | 2001-10-17 |
EP0458367A1 (de) | 1991-11-27 |
IL81737A0 (en) | 1987-10-20 |
IL81737A (en) | 1992-11-15 |
CN87102348A (zh) | 1987-12-09 |
AU1301792A (en) | 1992-09-03 |
JP2000023685A (ja) | 2000-01-25 |
JPS62296880A (ja) | 1987-12-24 |
ATE114168T1 (de) | 1994-12-15 |
EP0240208A3 (en) | 1989-05-03 |
CA1341601C (en) | 2010-03-09 |
ES2165348T3 (es) | 2002-03-16 |
DE3750755D1 (de) | 1994-12-22 |
JP3670889B2 (ja) | 2005-07-13 |
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