DE3751131D1 - Proteinartiger Proteaseinhibitor aus Streptomyces. - Google Patents
Proteinartiger Proteaseinhibitor aus Streptomyces.Info
- Publication number
- DE3751131D1 DE3751131D1 DE3751131T DE3751131T DE3751131D1 DE 3751131 D1 DE3751131 D1 DE 3751131D1 DE 3751131 T DE3751131 T DE 3751131T DE 3751131 T DE3751131 T DE 3751131T DE 3751131 D1 DE3751131 D1 DE 3751131D1
- Authority
- DE
- Germany
- Prior art keywords
- streptomyces
- protein
- protease inhibitor
- lep
- lti
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241000187747 Streptomyces Species 0.000 title abstract 2
- 239000000137 peptide hydrolase inhibitor Substances 0.000 title abstract 2
- 229940124158 Protease/peptidase inhibitor Drugs 0.000 title 1
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89724586A | 1986-08-18 | 1986-08-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3751131D1 true DE3751131D1 (de) | 1995-04-13 |
DE3751131T2 DE3751131T2 (de) | 1995-07-06 |
Family
ID=25407609
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3751131T Expired - Lifetime DE3751131T2 (de) | 1986-08-18 | 1987-08-17 | Proteinartiger Proteaseinhibitor aus Streptomyces. |
Country Status (9)
Country | Link |
---|---|
EP (3) | EP0264175B1 (de) |
AT (1) | ATE119572T1 (de) |
AU (1) | AU606888B2 (de) |
DE (1) | DE3751131T2 (de) |
DK (1) | DK205188A (de) |
IE (1) | IE950766L (de) |
PT (1) | PT85546B (de) |
WO (1) | WO1988001278A1 (de) |
ZA (1) | ZA876072B (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992000985A1 (en) * | 1990-07-11 | 1992-01-23 | Smithkline Beecham Corporation | Streptomyces vectors for production of heterologous proteins |
US5223418A (en) * | 1990-09-28 | 1993-06-29 | Smithkline Beecham Corporation | Method of improving the yield of heterologous proteins produced by streptomyces lividans |
WO1997011187A1 (en) * | 1995-09-22 | 1997-03-27 | Innogenetics N.V. | Subtilisin inhibitor of streptomyces venezuelae, and use of the gene sequences for expression and/or secretion of heterologous proteins in streptomyces |
KR101879852B1 (ko) * | 2017-04-28 | 2018-07-19 | 주식회사 만방바이오 | 신규 스트렙토마이세스속 균주 및 이의 용도 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5434837B2 (de) * | 1972-02-08 | 1979-10-29 | ||
US4717666A (en) * | 1984-03-05 | 1988-01-05 | Smithkline Beckman Corporation | Cloned streptomycete lividans excretable β-galactosidase gene |
EP0108303B1 (de) * | 1982-11-01 | 1987-02-04 | Miles Laboratories, Inc. | Verfahren zum Nachweis und zur Isolation eines Mikroorganismus |
-
1987
- 1987-08-17 DE DE3751131T patent/DE3751131T2/de not_active Expired - Lifetime
- 1987-08-17 EP EP87307260A patent/EP0264175B1/de not_active Expired - Lifetime
- 1987-08-17 WO PCT/US1987/002009 patent/WO1988001278A1/en not_active Application Discontinuation
- 1987-08-17 EP EP94110403A patent/EP0628632A1/de not_active Withdrawn
- 1987-08-17 EP EP19870905837 patent/EP0323959A4/de active Pending
- 1987-08-17 AT AT87307260T patent/ATE119572T1/de active
- 1987-08-17 IE IE950766A patent/IE950766L/xx unknown
- 1987-08-17 PT PT85546A patent/PT85546B/pt not_active IP Right Cessation
- 1987-08-17 AU AU78794/87A patent/AU606888B2/en not_active Ceased
- 1987-08-17 ZA ZA876072A patent/ZA876072B/xx unknown
-
1988
- 1988-04-14 DK DK205188A patent/DK205188A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE3751131T2 (de) | 1995-07-06 |
EP0323959A4 (de) | 1990-01-24 |
ATE119572T1 (de) | 1995-03-15 |
DK205188D0 (da) | 1988-04-14 |
AU606888B2 (en) | 1991-02-21 |
DK205188A (da) | 1988-04-14 |
ZA876072B (en) | 1988-07-27 |
EP0264175A1 (de) | 1988-04-20 |
IE950766L (en) | 1988-02-18 |
PT85546A (en) | 1987-09-01 |
EP0628632A1 (de) | 1994-12-14 |
EP0323959A1 (de) | 1989-07-19 |
PT85546B (pt) | 1990-05-31 |
WO1988001278A1 (en) | 1988-02-25 |
AU7879487A (en) | 1988-03-08 |
EP0264175B1 (de) | 1995-03-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |