DE3674043D1 - Pharmakologisch aktive mitomycinderivate. - Google Patents
Pharmakologisch aktive mitomycinderivate.Info
- Publication number
- DE3674043D1 DE3674043D1 DE8686302635T DE3674043T DE3674043D1 DE 3674043 D1 DE3674043 D1 DE 3674043D1 DE 8686302635 T DE8686302635 T DE 8686302635T DE 3674043 T DE3674043 T DE 3674043T DE 3674043 D1 DE3674043 D1 DE 3674043D1
- Authority
- DE
- Germany
- Prior art keywords
- mitomycine
- derivatives
- pharmacologically active
- pharmacologically
- active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- NWIBSHFKIJFRCO-WUDYKRTCSA-N Mytomycin Chemical class C1N2C(C(C(C)=C(N)C3=O)=O)=C3[C@@H](COC(N)=O)[C@@]2(OC)[C@@H]2[C@H]1N2 NWIBSHFKIJFRCO-WUDYKRTCSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7604785 | 1985-04-10 | ||
JP21044185 | 1985-09-24 | ||
JP27174285 | 1985-12-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3674043D1 true DE3674043D1 (de) | 1990-10-18 |
Family
ID=27302034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686302635T Expired - Lifetime DE3674043D1 (de) | 1985-04-10 | 1986-04-09 | Pharmakologisch aktive mitomycinderivate. |
Country Status (4)
Country | Link |
---|---|
US (1) | US4771068A (de) |
EP (1) | EP0197799B1 (de) |
JP (1) | JPH066591B2 (de) |
DE (1) | DE3674043D1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA86308B (en) * | 1985-02-25 | 1986-11-26 | Bristol Myers Co | In-vial deposition of 7-(dimethylaminomethylene)amino-9a-methoxy-mitosane |
JPS63150282A (ja) * | 1986-12-13 | 1988-06-22 | Kyowa Hakko Kogyo Co Ltd | マイトマイシン誘導体 |
JPH0249786A (ja) * | 1988-05-30 | 1990-02-20 | Kyowa Hakko Kogyo Co Ltd | 新規なマイトマイシン誘導体およびその中間体 |
WO1990001931A1 (en) * | 1988-08-23 | 1990-03-08 | Georgetown University | Mitomycin derivatives having reduced bone marrow toxicity, processes for their preparation, and the uses thereof |
JPH02167282A (ja) * | 1988-09-09 | 1990-06-27 | Kyowa Hakko Kogyo Co Ltd | マイトマイシン誘導体 |
US5091523A (en) * | 1990-04-25 | 1992-02-25 | Georgetown University | Mitomycin derivatives having reduced bone marrow toxicity, processes for their preparation, and the uses thereof |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2140799A (en) * | 1935-03-28 | 1938-12-20 | Andrew A Kucher | Multiple light sensitive tube |
NL129868C (de) * | 1963-06-07 | |||
US3332944A (en) * | 1964-11-02 | 1967-07-25 | American Cyanamid Co | Antibiotic derivatives of mitomycins a, b, c and porfiromycin |
JPS5673085A (en) * | 1979-11-20 | 1981-06-17 | Kyowa Hakko Kogyo Co Ltd | Preparation of mitomycin |
US4268676A (en) * | 1979-12-05 | 1981-05-19 | University Patents, Inc. | Mitomycin analogs |
US4617389A (en) * | 1981-05-15 | 1986-10-14 | University Patents, Inc. | Mitomycin analogs |
NZ199617A (en) * | 1981-05-15 | 1985-08-30 | University Patents Inc | Azirino(2',3',:3,4)pyrrolo(1,2-a)indole-4,7-dione derivatives and pharmaceutical compositions |
ZA833967B (en) * | 1982-06-04 | 1984-02-29 | Bristol Myers Co | Amidines |
JPS59175493A (ja) * | 1983-03-25 | 1984-10-04 | Kyowa Hakko Kogyo Co Ltd | マイトマイシン誘導体 |
JPS59104386A (ja) * | 1982-12-07 | 1984-06-16 | Kyowa Hakko Kogyo Co Ltd | マイトマイシン誘導体 |
DE116208T1 (de) * | 1982-12-07 | 1985-02-28 | Kyowa Hakko Kogyo Co., Ltd., Tokio/Tokyo | Mitomycin-analoge. |
KR840008362A (ko) * | 1983-04-11 | 1984-12-14 | 사무엘 제이. 두보프 | 아미노 이황산염 |
US4803212A (en) * | 1983-04-11 | 1989-02-07 | Bristol-Myers Company | Amino disulfides |
US4567256A (en) * | 1983-05-09 | 1986-01-28 | Bristol-Myers Company | Amidine process |
GB2140779B (en) * | 1983-06-01 | 1986-09-17 | Horticultural Containers Limit | Collapsible containers |
-
1986
- 1986-04-09 DE DE8686302635T patent/DE3674043D1/de not_active Expired - Lifetime
- 1986-04-09 EP EP86302635A patent/EP0197799B1/de not_active Expired - Lifetime
- 1986-04-09 JP JP61081808A patent/JPH066591B2/ja not_active Expired - Lifetime
- 1986-04-10 US US06/850,200 patent/US4771068A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH066591B2 (ja) | 1994-01-26 |
EP0197799B1 (de) | 1990-09-12 |
EP0197799A1 (de) | 1986-10-15 |
US4771068A (en) | 1988-09-13 |
JPS62228078A (ja) | 1987-10-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK394586A (da) | Fungicidt aktive propenoatderivater | |
DK175487D0 (da) | Farmaceutisk aktive 2-thiomethyl-substitueret-1,4-dihydro-pyridiner | |
DE3686172D1 (de) | Peptid-derivate. | |
ATE49403T1 (de) | N-aralkylpiperidinmethanol-derivate. | |
DE3766958D1 (de) | Isochinolin-derivate. | |
DE3675232D1 (de) | Pyridinderivate. | |
DE3685167D1 (de) | Calcitoningen-verwandte peptidderivate. | |
DE3678805D1 (de) | Indolderivate. | |
DE3667786D1 (de) | Substituierte naphthalinderivate. | |
IT8820550A0 (it) | Benzammidi sostituite farmacologicamente attive. | |
DE3672472D1 (de) | Aktive saumeinrichtung. | |
DE3680067D1 (de) | Fluorphenylcyclohexanderivate. | |
ATE41655T1 (de) | Phenaethanolaminderivate. | |
IT8521235A0 (it) | Composti farmacologicamente attivi. | |
DE3674043D1 (de) | Pharmakologisch aktive mitomycinderivate. | |
FI922720A0 (fi) | Farmakologiskt aktiva amidkarboxylatderivat. | |
DE3688788D1 (de) | Benzazepinderivate. | |
DE3682446D1 (de) | Isochinolinderivate. | |
FI865230L (fi) | Antikonvulsiva -tiobutyrolaktonderivat. | |
DE3778133D1 (de) | Mitomycinderivate. | |
DE3581680D1 (de) | Aktive muramylpeptidester-derivate. | |
IT8419413A0 (it) | Composti imidazopiridinici farmacologicamente attivi. | |
DE68908838D1 (de) | Pharmazeutisch wirksame Dithioketen-Derivaten. | |
IT8520726A0 (it) | Propionilanilidi farmacologicamente attive. | |
NO864162D0 (no) | Bicyklo-substituerte fenylacetonitrilderivater. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |