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DE3672251D1 - Herstellung von cholecalciferolderivaten und neue hierfuer verwendete zwischenprodukte. - Google Patents

Herstellung von cholecalciferolderivaten und neue hierfuer verwendete zwischenprodukte.

Info

Publication number
DE3672251D1
DE3672251D1 DE8686117422T DE3672251T DE3672251D1 DE 3672251 D1 DE3672251 D1 DE 3672251D1 DE 8686117422 T DE8686117422 T DE 8686117422T DE 3672251 T DE3672251 T DE 3672251T DE 3672251 D1 DE3672251 D1 DE 3672251D1
Authority
DE
Germany
Prior art keywords
production
intermediate products
products used
new intermediate
cholecalciferol derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686117422T
Other languages
English (en)
Inventor
Jeffrey Sterling
Ben-Zion Weiner
Dinora Barasch
Danielle Hirsch
Eliot Slovin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Industries Ltd
Original Assignee
Teva Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd filed Critical Teva Pharmaceutical Industries Ltd
Application granted granted Critical
Publication of DE3672251D1 publication Critical patent/DE3672251D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE8686117422T 1986-01-21 1986-12-15 Herstellung von cholecalciferolderivaten und neue hierfuer verwendete zwischenprodukte. Expired - Lifetime DE3672251D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL77668A IL77668A (en) 1986-01-21 1986-01-21 Production of cholecalciferol derivatives and novel intermediates used therefor

Publications (1)

Publication Number Publication Date
DE3672251D1 true DE3672251D1 (de) 1990-08-02

Family

ID=11056511

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686117422T Expired - Lifetime DE3672251D1 (de) 1986-01-21 1986-12-15 Herstellung von cholecalciferolderivaten und neue hierfuer verwendete zwischenprodukte.

Country Status (8)

Country Link
US (1) US4758382A (de)
EP (1) EP0230600B1 (de)
JP (2) JPS62169762A (de)
AT (1) ATE54138T1 (de)
AU (1) AU590644B2 (de)
DE (1) DE3672251D1 (de)
IL (1) IL77668A (de)
ZA (1) ZA869054B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
US5218109A (en) * 1988-07-05 1993-06-08 Kuraray Co., Ltd. Steroid compounds
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
DK0521550T3 (da) * 1991-07-05 1996-11-04 Duphar Int Res Vitamin D forbindelse, fremgangsmåde til fremstilling af denne forbindelse og mellemprodukt derfor
JP2876547B2 (ja) * 1992-06-23 1999-03-31 呉羽化学工業株式会社 抗クル病剤
WO1994004143A1 (en) * 1992-08-17 1994-03-03 Alcon Laboratories, Inc. Substituted hydrindanes for the treatment of angiogenesis-dependent diseases
US5464866A (en) * 1992-08-17 1995-11-07 Alcon Laboratories, Inc. Substituted hydrindanes for the treatment of angiogenesis-dependent diseases
JP3306468B2 (ja) * 1997-10-30 2002-07-24 セレスティカ・ジャパン・イーエムエス株式会社 自動ハンダ付け機構及びその機構を用いる装置並びにそのハンダ付け方法
PL188697B1 (pl) * 1998-01-14 2005-03-31 Inst Farmaceutyczny Sposób otrzymywania pochodnych cholekalcyferolu oraz nowe związki pośrednie
JP4752110B2 (ja) * 2000-12-25 2011-08-17 住友化学株式会社 トリフルオロプロペニル化合物の製造法
EP2144872A2 (de) * 2007-04-18 2010-01-20 Johns Hopkins University Gering kalzämische und hoch antiproliferative calcitriol-analoga

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3715374A (en) * 1972-05-05 1973-02-06 Wisconsin Alumni Res Found 24,25-dihydroxycholecalciferol
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives
JPS5735599A (en) * 1980-08-05 1982-02-26 Chugai Pharmaceut Co Ltd 24,25-dihydroxycholestane and its preparation
US4442093A (en) * 1981-05-15 1984-04-10 Kureha Kagaku Kogyo Kabushiki Kaisha Method for administering 24,25-dihydroxycholecalciferol to persons suffering from hypercalcemia
DE3471928D1 (en) * 1983-01-28 1988-07-14 Hoffmann La Roche Process for the preparation of cholecalciferol derivatives
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
DE3565401D1 (de) * 1984-02-08 1988-11-10 Hoffmann La Roche Calciferol derivatives

Also Published As

Publication number Publication date
JPS62169762A (ja) 1987-07-25
AU6601086A (en) 1987-07-23
EP0230600B1 (de) 1990-06-27
EP0230600A1 (de) 1987-08-05
JPH0424346B2 (de) 1992-04-24
JP2505669B2 (ja) 1996-06-12
AU590644B2 (en) 1989-11-09
JPH054962A (ja) 1993-01-14
US4758382A (en) 1988-07-19
ATE54138T1 (de) 1990-07-15
ZA869054B (en) 1987-07-29
IL77668A (en) 1989-03-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee