DE3667290D1 - Boronsaeureaddukte von technetium-99m-dioximkomplexen. - Google Patents

Boronsaeureaddukte von technetium-99m-dioximkomplexen.

Info

Publication number: DE3667290D1
Authority: DE; Germany
Prior art keywords: technetium; boronic acid; acid adducts; dioxime complexes; dioxime
Prior art date: 1985-04-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE8686105172T

Other languages

English (en)

Inventor

Adrian D Nunn

Elizabeth N Treher

Thomas A Feld

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bracco International BV

Original Assignee

ER Squibb and Sons LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-15

Filing date

1986-04-15

Publication date

1990-01-11

1986-04-15 Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC

1990-01-11 Application granted granted Critical

1990-01-11 Publication of DE3667290D1 publication Critical patent/DE3667290D1/de

2006-04-16 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Physics & Mathematics (AREA)
Medicinal Chemistry (AREA)
Optics & Photonics (AREA)
Pharmacology & Pharmacy (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Absorbent Articles And Supports Therefor (AREA)

DE8686105172T 1985-04-15 1986-04-15 Boronsaeureaddukte von technetium-99m-dioximkomplexen. Expired - Lifetime DE3667290D1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/723,601 US4705849A (en)	1985-04-15	1985-04-15	Boronic acid adducts of technetium-99m dioxime complexes

Publications (1)

Publication Number	Publication Date
DE3667290D1 true DE3667290D1 (de)	1990-01-11

Family

ID=24906933

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE8686105172T Expired - Lifetime DE3667290D1 (de)	1985-04-15	1986-04-15	Boronsaeureaddukte von technetium-99m-dioximkomplexen.

Country Status (11)

Country	Link
US (1)	US4705849A (de)
EP (1)	EP0199260B1 (de)
JP (2)	JPS61238794A (de)
AT (1)	ATE48429T1 (de)
AU (1)	AU583101B2 (de)
CA (1)	CA1257288A (de)
DE (1)	DE3667290D1 (de)
DK (1)	DK168920B1 (de)
IE (1)	IE58944B1 (de)
NZ (1)	NZ215513A (de)
ZA (1)	ZA862057B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4714605A (en) *	1986-10-14	1987-12-22	E. R. Squibb & Sons, Inc.	Technetium-99m labeled dioxime complexes
AU1966188A (en) *	1987-08-07	1989-03-09	Mallinckrodt, Inc.	Diagnostic or radiotherapeutic composition comprising a hydrogen containing compound
US4871836A (en) *	1987-10-13	1989-10-03	E. R. Squibb & Sons, Inc.	Boronic acid adducts of rhenium and radioactive isotopes of rhenium dioxime complexes
US5262175A (en) *	1989-05-10	1993-11-16	Solanki Kishor K	Stabilization of radiopharmaceutical compositions
US5039795A (en) *	1989-06-21	1991-08-13	E. R. Squibb & Sons, Inc.	Preparation of boronic acid derivatives
US5069900A (en) *	1989-08-28	1991-12-03	E. R. Squibb & Sons, Inc.	Boronic acid adducts of technetium-99m dioxime-imine complexes
US5118797A (en) *	1989-08-28	1992-06-02	E. R. Squibb & Sons, Inc.	Rhenium tris dioxime complexes
US5377681A (en) *	1989-11-13	1995-01-03	University Of Florida	Method of diagnosing impaired blood flow
US5080884A (en) *	1989-12-12	1992-01-14	Medi-Physics, Inc.	Hydrocarbylphenyl diaminodithiol radionuclide complexes and their use in imaging
US5026913A (en) *	1989-12-12	1991-06-25	Medi-Physics, Inc.	Hydrocarbylphenyl diaminodithiol derivatives
CA2034042C (en) *	1990-01-18	1999-08-17	Adrian D. Nunn	Boronic acid adducts of rhenium dioxime and technetium-99m dioxime complexes containing a biochemically active group
US5183653A (en) *	1990-04-13	1993-02-02	E. R. Squibb & Sons, Inc.	Boronic acid adducts of metal dioxime complexes useful in labelling proteins and other amine-containing compounds
US5545397A (en) *	1991-10-23	1996-08-13	Boron Biologicals, Inc.	Contrast agents and compositions for radiological imaging, and radiological imaging method utilizing same
US5256394A (en) *	1991-10-23	1993-10-26	Boron Biologicals, Inc.	Radiological imaging method, and contrast media reagents therefor
US5808091A (en)	1991-10-29	1998-09-15	Bracco International B.V.	Rhenium and technetium complexes containing a hypoxia localizing moiety
US6409987B1 (en)	1999-04-07	2002-06-25	Intimax Corporation	Targeted agents useful for diagnostic and therapeutic applications
US6056941A (en) *	1999-07-28	2000-05-02	Bracco Research Usa	Kit for the preparation of technetium TC 99m teboroxime myocardial perfusion agent
US7026415B2 (en) *	2004-02-17	2006-04-11	Equistar Chemicals, Lp	Clathrochelates as olefin polymerization catalyst components
CN107674098B (zh) *	2017-06-26	2021-12-07	中国医学科学院阜外医院	一类含芳基硼酸的99mTc配合物及其药盒配方和应用
CN111377968B (zh) *	2020-03-09	2023-07-25	中国医学科学院阜外医院	一类含芳基硼酸的99mTc(Ⅲ)配合物及其药盒配方和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4387087A (en) *	1980-04-18	1983-06-07	Research Corporation	Cationic lipophilic complexes of 99m Tc and their use for myocardial and hepatobiliary imaging
US4615876A (en) *	1983-04-25	1986-10-07	Curators Of The University Of Missouri	Macrocyclic complexes of technetium-99m for use as diagnostic radionuclides

1985
- 1985-04-15 US US06/723,601 patent/US4705849A/en not_active Expired - Lifetime
1986
- 1986-03-18 NZ NZ215513A patent/NZ215513A/xx unknown
- 1986-03-19 ZA ZA862057A patent/ZA862057B/xx unknown
- 1986-03-20 AU AU54927/86A patent/AU583101B2/en not_active Ceased
- 1986-03-24 CA CA000504793A patent/CA1257288A/en not_active Expired
- 1986-03-24 IE IE75486A patent/IE58944B1/en not_active IP Right Cessation
- 1986-04-14 DK DK169086A patent/DK168920B1/da not_active IP Right Cessation
- 1986-04-15 DE DE8686105172T patent/DE3667290D1/de not_active Expired - Lifetime
- 1986-04-15 JP JP61087851A patent/JPS61238794A/ja active Granted
- 1986-04-15 AT AT86105172T patent/ATE48429T1/de not_active IP Right Cessation
- 1986-04-15 EP EP86105172A patent/EP0199260B1/de not_active Expired
1991
- 1991-01-31 JP JP3056255A patent/JPH0714888B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IE58944B1 (en)	1993-12-01
IE860754L (en)	1986-10-15
CA1257288A (en)	1989-07-11
ZA862057B (en)	1986-11-26
JPH0714888B2 (ja)	1995-02-22
DK169086D0 (da)	1986-04-14
EP0199260A3 (en)	1987-04-15
JPH061725A (ja)	1994-01-11
NZ215513A (en)	1988-10-28
US4705849A (en)	1987-11-10
EP0199260B1 (de)	1989-12-06
JPH0411553B2 (de)	1992-02-28
ATE48429T1 (de)	1989-12-15
DK169086A (da)	1986-10-16
AU5492786A (en)	1986-10-23
EP0199260A2 (de)	1986-10-29
JPS61238794A (ja)	1986-10-24
AU583101B2 (en)	1989-04-20
DK168920B1 (da)	1994-07-11

Publication	Publication Date	Title
DE3667290D1 (de)	1990-01-11	Boronsaeureaddukte von technetium-99m-dioximkomplexen.
MX3173A (es)	1993-09-01	Complejos de flavanolignanos/fosfolipidos y procedimiento de obtencion.
ATE77056T1 (de)	1992-06-15	Antikoerperkomplexe von haptenmodifizierten diagnostischen oder therapeutischen mitteln.
DE3670310D1 (de)	1990-05-17	Elektrochemische behandlung von ligninen.
ES2036555T3 (es)	1993-06-01	Procedimiento para preparar complejos de dioxima marcada con tecnecio-99m y estuche adecuado para marcar con tecnecio-99m.
IT1177889B (it)	1987-08-26	Proteine umane,antisieri per esse,procedimento per prepararli e corre di di prova che li contengono
ATE80888T1 (de)	1992-10-15	Borsaeureaddukte von dioximkomplexen von rhenium und radioaktiven rhenium-isotopen.
FI864597A0 (fi)	1986-11-12	Kardiotoniska tiazoloner.
NO873213D0 (no)	1987-07-31	Fremgangsmaate for fremstilling av transdermale preparater.
DE3686472D1 (de)	1992-09-24	Cardiotonische phenyloxazolone.
FR2544320B1 (fr)	1986-07-11	Amides bis (2,2-dimethyl-1-aziridinyl) phosphiniques et leur utilisation dans le traitement de tumeurs
MX9102087A (es)	1992-10-30	Complejos que contienen acidos s(+) fenilalcanos y acidos alfa-hidroxi alcanos.
ES8704268A1 (es)	1987-03-16	Procedimiento para la determinacion cinetica de la actividad del sistema de complemento de sangre de ser humano o de animal mamifero.
DE3872790D1 (de)	1992-08-20	Geraet zur untersuchung von reissverschlusselementen.
NO870398D0 (no)	1987-01-30	Fremgangsmaate for fremstilling av terapeutisk aktive organiskeplatinakomplekser.
BG44876A3 (bg)	1989-02-15	Метод за получаване на кондензирани аs-триазини
ATE104147T1 (de)	1994-04-15	Verwendung von inositol-triphosphat zur behandlung von metallvergiftung.
FI863404A0 (fi)	1986-08-22	Kardiotoniska fosfodiesterasinhibitorer i komplex med vattenloesliga vitaminer.
ATE51899T1 (de)	1990-04-15	Elektrochemische behandlung von ligninen.
AT342700B (de)	1978-04-10	Metallrahmen fur den aufbau von schaltschranken in elektrischen anlagen
DE68906794D1 (de)	1993-07-01	Zubereitungen zur behandlung von leishmaniasis.
IT8619471A0 (it)	1986-02-20	Procedimento di tintura e preparati per tintura per la realizzazione del procedimento.

Legal Events

Date	Code	Title	Description
1991-01-03	8364	No opposition during term of opposition
1995-08-24	8327	Change in the person/name/address of the patent owner	Owner name: BRACCO INTERNATIONAL B.V., AMSTERDAM, NL
1995-08-24	8328	Change in the person/name/address of the agent	Free format text: UEXKUELL & STOLBERG PATENTANWAELTE, 22607 HAMBURG