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DE3585867D1 - Analoge vom wachstumshormon befreiter faktor und dessen verfahren. - Google Patents

Analoge vom wachstumshormon befreiter faktor und dessen verfahren.

Info

Publication number
DE3585867D1
DE3585867D1 DE8585111959T DE3585867T DE3585867D1 DE 3585867 D1 DE3585867 D1 DE 3585867D1 DE 8585111959 T DE8585111959 T DE 8585111959T DE 3585867 T DE3585867 T DE 3585867T DE 3585867 D1 DE3585867 D1 DE 3585867D1
Authority
DE
Germany
Prior art keywords
analogs
growth hormone
hormone released
released factor
factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585111959T
Other languages
English (en)
Inventor
Arthur Martin Felix
Edgar P Heimer
Thomas F Mowles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/653,163 external-priority patent/US4622312A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE3585867D1 publication Critical patent/DE3585867D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE8585111959T 1984-09-24 1985-09-20 Analoge vom wachstumshormon befreiter faktor und dessen verfahren. Expired - Lifetime DE3585867D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/653,163 US4622312A (en) 1984-09-24 1984-09-24 Growth hormone releasing factor analogs
US06/762,891 US4649131A (en) 1984-09-24 1985-08-06 Growth hormone releasing factor analogs

Publications (1)

Publication Number Publication Date
DE3585867D1 true DE3585867D1 (de) 1992-05-21

Family

ID=27096450

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585111959T Expired - Lifetime DE3585867D1 (de) 1984-09-24 1985-09-20 Analoge vom wachstumshormon befreiter faktor und dessen verfahren.

Country Status (11)

Country Link
US (1) US4649131A (de)
EP (1) EP0177819B1 (de)
JP (1) JPH0674279B2 (de)
AU (1) AU589373B2 (de)
CA (1) CA1270598A (de)
DE (1) DE3585867D1 (de)
DK (1) DK164408C (de)
IE (1) IE59240B1 (de)
IL (1) IL76440A (de)
NZ (1) NZ213566A (de)
PH (1) PH23324A (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1271600A (en) * 1985-01-07 1990-07-10 David Howard Coy Growth hormone-releasing peptides and method of treating mammals therewith
US4734399A (en) * 1985-08-06 1988-03-29 Hoffmann-La Roche Inc. Growth hormone releasing factor analogs
US4689318A (en) * 1985-08-29 1987-08-25 The Salk Institute For Biological Studies GRF analogs
US4880778A (en) * 1986-05-12 1989-11-14 Eastman Kodak Company Combinations having synergistic growth hormone releasing activity and methods for use thereof
JPS63243096A (ja) * 1987-03-27 1988-10-07 Sumitomo Pharmaceut Co Ltd ポリペプチドの製造法
US5001223A (en) * 1987-05-26 1991-03-19 Merck & Co., Inc. Parathyroid hormone antagonists with enhanced metabolic properties
US4839344A (en) * 1987-06-12 1989-06-13 Eastman Kodak Company Polypeptide compounds having growth hormone releasing activity
USRE33699E (en) * 1987-07-09 1991-09-24 International Minerals & Chemical Corp. Growth hormone-releasing factor analogs
US4801456A (en) * 1987-07-09 1989-01-31 International Minerals & Chemical Corp. Growth hormone-releasing factor analogs
US4880777A (en) * 1987-09-01 1989-11-14 Eastman Kodak Company Synthetic peptides having growth hormone releasing activity
EP0400051B1 (de) * 1988-01-28 1995-05-10 Polygen Holding Corporation Polypeptide mit hormonwachstumsbefreiender wirkung
EP0326418A1 (de) * 1988-01-29 1989-08-02 The Upjohn Company GRF-Analoge
US4929600A (en) * 1988-03-18 1990-05-29 University Of Deleware Endocrine manipulation to improve body composition of poultry
US5168102A (en) * 1988-03-18 1992-12-01 University Of Delaware Endocrine manipulation to improve body composition of poultry
US5023322A (en) * 1988-08-31 1991-06-11 Mta Kutatas-Es Szervezetelemzo Intezete Analogs of growth hormone releasing factor (GRF) and a method for the preparation thereof
US5084442A (en) * 1988-09-06 1992-01-28 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5756458A (en) * 1989-06-16 1998-05-26 Pharmacia & Upjohn Company Stabilized potent GRF analogs
US5132401A (en) * 1989-09-19 1992-07-21 George Washington University, Office Of Sponsored Research MB-35 a peptide enhancing the production of growth hormone and prolactin from the anterior pituitary
CA2082059A1 (en) * 1990-05-04 1991-11-05 David H. Coy Synthetic grf analogs
EP0544706A4 (en) * 1990-06-29 1993-10-13 Hoffmann-La Roche Inc. Histidine substituted growth hormone releasing factor analogs
ATE119916T1 (de) * 1990-12-10 1995-04-15 Hoffmann La Roche Verfahren zur enzymatischen herstellung von grf(1-44)nh2.
JPH05507939A (ja) * 1991-04-09 1993-11-11 エフ・ホフマン―ラ　ロシユ　アーゲー 成長ホルモン放出因子の類似体
US5262519A (en) * 1991-05-15 1993-11-16 The Salk Institute For Biological Studies GRF analogs XI
US5246920A (en) * 1992-06-15 1993-09-21 University Of South Florida Treatment of hyperprolactinemia
US5811074A (en) * 1992-06-29 1998-09-22 University Of South Florida Method of diagnosing pituitary dependent growth hormone deficiency
US5550212A (en) * 1993-12-17 1996-08-27 The Administrators Of The Tulane Educational Fund Analogues of hGH-RH(1-29)NH2 having antagonistic activity
AU5441096A (en) * 1995-04-14 1996-10-30 The Administrators Of The Tulane Eductional Fund Analogs of growth hormone-releasing factor
AU2382097A (en) * 1996-04-19 1997-11-12 Novo Nordisk A/S Compounds with growth hormone releasing properties
US5990084A (en) * 1996-04-19 1999-11-23 Novo Nordisk A/S Compounds with growth hormone releasing properties
WO2011153491A2 (en) 2010-06-03 2011-12-08 University Of Miami Agonists of growth hormone releasing hormone as effectors for survival and proliferation of pancreatic islets
US9079974B2 (en) 2011-12-21 2015-07-14 The University Of Miami GH-RH analogs with potent agonistic effects
US9855312B2 (en) 2012-12-21 2018-01-02 University Of Miami GHRH agonists for the treatment of ischemic disorders
WO2014100816A2 (en) 2012-12-21 2014-06-26 University Of Miami Ghrh agonists for islet cell transplantation and function and the treatment of diabetes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4529595A (en) * 1983-01-13 1985-07-16 The Salk Institute For Biological Studies GRF Analogs
US4563352A (en) * 1982-10-04 1986-01-07 The Salk Institute For Biological Studies Human pancreatic GRF
US4518586A (en) * 1983-01-13 1985-05-21 The Salk Institute For Biological Studies GRF Analogs III
IL70530A (en) * 1983-01-13 1986-09-30 Salk Inst For Biological Studi Synthetic peptides having growth hormone releasing factor activity and compositions containing them
US4617149A (en) * 1983-09-21 1986-10-14 Eli Lilly And Company Growth hormone release factor analogs
US4528190A (en) * 1983-10-25 1985-07-09 The Salk Institute For Biological Studies GRF Analogs IV
US4562175A (en) * 1984-02-03 1985-12-31 Ding Chang Synthetic peptides

Also Published As

Publication number Publication date
EP0177819B1 (de) 1992-04-15
IL76440A0 (en) 1986-01-31
AU589373B2 (en) 1989-10-12
EP0177819A2 (de) 1986-04-16
EP0177819A3 (en) 1989-02-08
NZ213566A (en) 1989-01-06
DK164408B (da) 1992-06-22
US4649131A (en) 1987-03-10
IE59240B1 (en) 1994-01-26
IL76440A (en) 1989-08-15
DK164408C (da) 1992-11-09
AU4768385A (en) 1986-04-10
JPS61118400A (ja) 1986-06-05
CA1270598A (en) 1990-06-19
JPH0674279B2 (ja) 1994-09-21
DK433485A (da) 1986-03-25
IE852341L (en) 1986-03-24
PH23324A (en) 1989-07-14
DK433485D0 (da) 1985-09-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee