DE1569231A1 - Adhesive - Google Patents

Description

DR. ELISABETH JUNG. DR. VOLKER VOSSIUS ₁ DIPL.-ING. GERHARD COLDEWEY

PATENT LAWYERS '_ _ _ , MDNCHEN 23 · S I E G FS8T RASS E 26 ■ TELEPHONE 345087. TELEGR AM M ADDRESS: INVENT / MDNCHEN

P 15 69 251 * 6

(0 10 388 lVo / 39b)

UZ & 516 (Be / vo)

USSN 310 162
330 271

E.R.SQUIBB <fc SONS, INCo New York, H-Y., V.St.A. '

"Adhesive"

The invention relates to an adhesive <> In particular, the invention relates to a pressure-sensitive adhesive, which may be used together with organic solvents for gluing or sealing wet surfaces such as Paper, wood, cloth, pipes, leaks in boats or coffin surfaces can be used*

There is one disadvantage of known pressure-sensitive adhesives in that they do not adhere to wet surfaces. finally come into contact with water, so go Adhesive properties are lost when the surfaces become damp.

A new adhesive was found that immediately applied to the a wide variety of «wet surfaces and their® adhesive properties does not lose when stuck with the adhesive dry surfaces become damp.

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New ume

The adhesive according to the invention is characterized by a content of a water-soluble or swellable hydrocolloid or a mixture of such hydrocolloids mixed with a water-insoluble, viscous , chewy-chewy binder. The hydrocolloid is, for example, polyvinyl alcohol, powdered pectin, gum arabic, gelatin, an alginate or carraghenate , Carboxymethyl cellulose, high molecular weight polyethylene glycols and methoxypolyethylene glycols (Oarbowax), carboxypolymethylene, polyoxyethylene and similar substances. The binders used are viscous, water-insoluble, natural or synthetic rubber-like substances, such as polyisobutylene or sucrose acetate isobutylate or an elastomer mixture such as natural rubber, silicone rubber, acrylonitrile rubber, polyurethane rubber and mixtures of such substances, which preferably include a tackifier, such as a rosin resin, such as a colophony resin of hydrogenated rosin or a pentaerythritol ester of hydrogenated rosin is added. The viscous, rubber or plant slime-like substance acts as an adhesive that adheres to dry surfaces and as a binding agent for the hydrocolloid parts and makes the finished adhesive elastic and pliable.

In addition to the constituents mentioned, various organic solvents or plasticizers can be added to the adhesive in order to improve the adhesive properties and / or to provide the desired consistency. Such solvents are, for example, chloroform, various halogenated hydrocarbons (trichloromonofluoromethane, difluorodichloromethane, CClP ₂ - OClPg 'methylene chloride), carbon disulfide and various esters such as amyl acetate. Mineral oils, petrolatum (petrolatum) and similar substances can be added to the adhesives as plasticizers.

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BAD ORJGfHAi

A mixture of polyisobutylene and those incorporated therein Sodium Carboxymethyloellulose supplies as stated has produced excellent results and is therefore preferred. In those cases where a clear adhesive is desired, A mixture of polyisobutylene and a polyoxyethylene with a high molecular weight was found to be extremely suitable. In combination with these preferred adhesives, a mixture of mineral oil as plasticizer and chloroform or Kethylene chloride can preferably be used as a solvent.

The adhesives according to the invention can be used as such for Adhesive coatings after evaporation of the solvent or on carriers such as paper, regenerated cellulose film (cell glass) cellulose regenerated material which can be dialysed or is coated with other polymers such as polyethylene and is applied to various plastics such as polyvinylidene chloride film or films made of fluoride halogenated hydrocarbons will.

If the adhesives according to the invention are applied to a tape-shaped strip, they can, for example as temporary sealing material, e.g. for leaks in boats and ships or pipelines, or for bandages for damp Areas of the body are used that are not covered by silence education, peel off when swimming or bathing. They are therefore particularly suitable for bandages, e.g. for athletes. In veterinary medicine, such adhesive strips can be used, for example, as dressings for fish and those living in the water Mammals are used. The adhesives according to the invention can also be used as adhesives for bindings, that are used for trees or other plant species that are exposed to moisture. You can also use it as a Adhesives are used for labels on very damp surfaces, e.g. in refrigerators and freezers.

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In combination with a solvent to reduce viscosity »- The adhesive compositions according to the invention can be present in various forms that they can be used with, for example Make applicator rollers, in mechanical spray equipment and as aerosols suitable.

If necessary, drugs such as insulin, antibiotics, e.g. amphotericin and tetracycline, anesthetics such as benzoain, anti-inflammatory agents such as triamcinolone acetonide or sodium fluoride for the treatment of caries in the adhesives according to of the invention incorporated or on this on the contact surface with the parts of the skin or parts of plants to be treated dusted, sprayed or spread.

The invention is illustrated in more detail by the following examples.

example 1

58 g of polyisobutylene are heated to 70 to 80 ° C »Man mixed 42 g of sodium carboxymethyl cellulose powder with the heated polyisobutylene and let the mixture cool down. A dough-like mass is formed, which is placed on a mixing roller for more even mixing, and then pressed in a hydraulic press to the desired thickness. You then press a thin one on one side Polyethylene film and cut the resulting laminate into strips, squares or other shapes of the desired Size.

Example 2

The procedure described in Example 1 is repeated, however, the 58 g of polyisobutylene are replaced by a mixture of 56 g of polyisobutylene and 2 g of Vaseline. Here, too, a satisfactory association is obtained.

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Example ^ ₁ ,

The procedure described in Example 1 is repeated, however, the 58 grams of polyisobutylene are made by a blend replaced by 55 g of polyisobutylene and 1 g of mineral oil preheated to 70 to 80 ° C. Here, too, you get a satisfactory one Association.

Example 4

The procedure described in Example 1 is repeated, however, the 42 g of sodium arboxymethyl cellulose gets through 42 g of finely powdered polyvinyl alcohol replaces

Example _i \

The procedure described in Example 1 is repeated, but the sodium c-rboxymethyl cellulose is replaced by 42 g Gum arabic replaced.

The procedure described in Example 1 is repeated, but using a mixture of 30 g of gum arabic and 12 g of a powdered mixture of gelatin, pectin and sodium carboxymethyloellulose, thus obtaining a satisfactory one Association.

Example 7

The procedure described in Example 1 is repeated however, 37 g are combined before addition to the polyisobutylene Sodium carboxymethyloellulose with 5 g of ethyl p-aminobenzoate, to get a drug bandage.

Example - 8

The process described in Example 1 is repeated, but instead of 42 g of sodium carboxymethyloellulose, 38 g of this compound, 3 g of amphotericin B and 1 g are used

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letracyclinebase to obtain an isiedicament dressing.

The method described in Example 1 is repeated, but no polyethylene film is used and the dough-like adhesive mass is applied directly between surfaces to be bonded.

Example 10

The procedure described in Example 1 is repeated, except that 42 g of sodium carboxymethyl cellulose are used instead 39 g of this compound and 3 g of insulin, and receives a drug bandage.

Example 11

The procedure described in Example 1 is repeated, but using 22 g instead of polyisobutylene Sucrose acetate isobutyrate and 33 g sodium carboxyethyl cellulose. The adhesive mass obtained can then be used directly be used as a bandage, or worn before use, a water-insoluble polyethylene film on it.

Example 12

The procedure described in Example 1 is repeated, but instead of the polyethylene film, a film is made a Fluoihalogenohlenwasserstoff polymer used. Man receives a well-adhering adhesive tape. If a paper label is used instead of the polyethylene film a label that adheres well to wet surfaces. As well as adhesive strips are made using cellulose film or a flexible polyvinyl chloride sheet instead of the Polyethylene film received.

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Example Ij

An adhesive is made from the following components: ifatriuincarboxymethylcelluloBe 40.0 g

Pentaerythritol ester of hydrogenated rosin 20.0 g

Natural rubber 30.0 g Polyisobutylene 10.0 g

Sas polyisobutylene, the rubber and the rosin ester are mixed until a uniform mixture has been obtained and then the sodium oarboxymethylcellulose is added and mixed again until a uniform mass has been obtained. The dough-like mass can are applied according to Example 1 to adhesive tape.

Example 14 An adhesive is made from the following materials:

high polymer polyoxyethylene (Polyox N-3000) 37, above

Polyterpene resin (Piccolyte S-115) 10.0 g Polyisobutylene (Vistonex LH MS) 10.0 g Polyisobutylene (Vistonex MM L-100) 8.0 g Mineral heavy oil 15.0 g Chloroform 400 oar

The polyisobutylenes are dissolved in the chloroform in a closed container, and after they are completely dissolved becomes the ethylene oxide polymer, the polyterpene resin and the Mineral oil is added and the mixture is stirred until the components are uniformly dispersed. A slimy mass is obtained, which can be applied for gluing surfaces, e.g. by brushing or rolling on.

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Ί569231

- ο -

Example 15 Sine adhesive mask suitable for application by spray

is made from the following materials:

high polymer polyoxyethylene (Polyox N-750) 20, above

Pentaerythritol ester of hydrogenated Rosin 20.0 g

Polychloroprene rubber (Neoprene GRT) 20.0 g Methylene chloride 600

The ingredients become one by dissolving and mixing in a closed container until homogeneous processed liquid adhesive.

Example 16

An adhesive suitable for bandages is made up of the following Fabrics made:

Diethylamino-2,6-dimethylaoetanilide 2.0 g Sodium carboxymethyl cellulose 40.0 g

Sodium alginate 10.0 g tragacanth 8.0 g

Polyisobutylene (Vistonex ML MH) 40.0 g

The diethylamino-2,6 ~ dimethylacetanilide, sodium carboxymethyl cellulose, sodium alginate and tragacanth, all in In powder form, are mixed until homogeneous, and the mixture obtained is added to the polyisobutylene in a Sigma mixer and mixed until a uniform mass is formed. The mass can be rolled out into plates that have a waterproof base on one side and on wear removable protective paper on the other side »Ib can also have a removable protective pajpier on both sides be covered and then form a dressing material suitable for various medical and dental purposes.

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156923t

Example 17

One suitable for use in an aerosol spray container Adhesive is made from the following materials:

high polymer polyoxyethylene (Polyox N-750) 20.0 g

Polyterpene resin (Piccolyte S-115) 10.0 g

Polyisobutylene (Vistonex LM MS) 10.0 g

Butyl rubber 8.0 g

Trichlorofluoroethane 200.0 g

Diehlordifluoromethan 200.0 g

The ingredients are mixed in a closed Container dissolved and dispersed until homogeneous and an adhesive obtained in pressure containers for aerosols can be bottled.

Example 18
An adhesive is made from the following substances:

Sodium arboxymethyl cellulose 40.0 g

Pentaerythritol ester of hydrogenated rosin

Natural rubber. short-fiber asbestos titanium dioxide pigment

Methyl 1-hydroxybenzoate (preservative)

Polyisobutylene (Vistonex LM MH)

The polyisobutylene is poured into a Sigma-tfischer, and then remaining ingredients are added and up. mixed to homogeneity at about 93 ° 0. The adhesive obtained is rolled into plates. One side of the plate is covered with removable protective paper and the other side with a metal or Plastic film covered. The adhesive plaster obtained can after cutting to the appropriate size as self-adhesive sealing material for leaks e.g. in boats

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14.0 S. 30.0 G 5.5 G 0.3 G 0.2 S. 10.0 G

40.0 G 15.0 S. 45.0 G 10.0 G 600 cnr 200 cur

or ships, walls or pipelines.

Example 19 An adhesive is made from the following substances:

high-polymer polyoxyethylene (Polyox N-3000)

Polyisobutylene (Vistonex MM L-IOO) * Polyisobutylene (Vistonex LM MH) Mineral oil Methylene chloride

Heptane

Methylene chloride and heptane are placed in a closed container, the other ingredients are added and up mixed together for homogeneity of the mixture. The colloidal dispersion obtained can then be applied to cellulose film or a transparent plastic film and evaporating the solvent to obtain a pressure-sensitive adhesive tape.

Example 20

The adhesive produced according to Example 19 is applied to a flexible base, as it is used for medical adhesive plaster, applied and the free adhesive layer covered with removable protective paper. The adhesive plaster is for use by swimmers and other athletes Fish, aquatic mammals or trees, where the patch is exposed to high levels of moisture.

- patent claims -

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Claims (5)

Pat ent claims 1. Velcro, characterized by a Content of a water-soluble or swellable hydrocolloid or a mixture of such hydrocolloids in admixture with a water-insoluble, viscous, chewy-like Binder. 2. Klet mass naoh claim 1, characterized in that the hydrocolloid is a polyvinyl alcohol, Pectin, gelatine, an alginate, a garraghenate, carboxymethyl cellulose, a high molecular weight polyethylene glycol or methyloxypolyethylene glycol, carboxypolymethylene or whose Gemisoh is. Adhesive composition according to Claims 1 and 2, characterized in that the binder is polyisobutylene or saccheroe acetate isobutyrate or a mixture of Natural rubber, silicone rubber, acrylonitrile rubber and / or polyurethane rubber with rosin, a polyterpene resin and / or a glycerin ester or pentaerythritol ester of hydrogenated rosin is 4. Adhesive according to Claims 1 to 3, characterized due to an additional content of an organic solvent » 5. Adhesive according to claim 4, characterized in that the solvent is a hydrocarbon or halogenated hydrocarbon, carbon disulfide, amyl acetate or a mixture of these compounds. 6, adhesive according to claim 51, characterized in that the solvent is a mixture of Mineral oil and chloroform is. 909 8 3 4/1297 Ntut nterlagen i ^ zMumMmimimmm ^ fr,