DE1492001A1 - Cosmetic agent - Google Patents

Description

June 25, 1965 Eg / Sl / La

Laboratoires Pharmascience, 5 * avenue de la Cigale Asnieres (Seine), France

Cosmetic agent

The invention relates to cosmetics such as skin cream, lotions, liquid or solid soaps or bar soaps Surface-active substances that contain sulfur in bound form and that have a mild and caring effect exercise on the skin.

The invention relates to cosmetic agents with an oil content of at least one alkyl ether Polyalkylene glycol of the formula:

R 'RS- (CH ₀ -IjH-O) _n H

in which R eirm is an alkyl radical, preferably a branched alkyl radical having 6 to 18 carbon atoms, R ^{1 is} a hydrogen atom or a methyl group and η is an integer between 1 and 14.

Thus, the varätherte radical R can be a straight octyl-nonyl, Do4 "oyl", cetyl or steryl radical or from the branched cis-polymer dee propylene ^! t consist of 18 carbon atoms.

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The tertiary dodecyl thioether of polyethylene glycol has proven to be particularly favorable for the purpose of the invention the formula

proven, which can be used in the form of an isomeric mixture. Connections are preferred here, in which η has about the value of 12. These thioethers mainly contain residues of polyethylene glycol with η = 12, which are also accompanied by compounds in which η = 11 and η = IJ. Thioether, in whose polyethylene glycol residues the number η = 10 and = 14 are only present in very small amounts. The sulfur content of such a compound is about 4.2 to 4.5 ^.

The alkylthioethers of polyalkylene glycols used according to the invention are generally obtained by polyaddition of an alkylene oxide onto a straight-chain or branched alkyl mereaptane manufactured. Since they are widely used in industry, for example as textile treatment agents, they are available in stores. For use as part of the cosmetic compositions of the invention it is sufficient to purify the commercial products and especially to lower their old content, preferably below an iron content of 0.5 per mille. This purification can be carried out by the usual methods, such as by distillation, treatment with charcoal or Treatment with infusion soil.

After purification, a mixture of isomers of the tertiary dodeoyl thioether of Pqlyäthylenenglykol, for example the following characteristic data:

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Iron content »less than 0.5 per mille

Mineral salt content: less than 1 per mille. Average molecular weight: 750 - 760

ο specific gravity t 1220-1030 cloud point of the pure
Product ι 91 ° C

pH value in a liquid solution t 7 * 3

The alkylthioethers of the polyalkylene glycols can be used as a constituent of any cosmetic agent, such as creams, facial tonics and various soaps, and they are generally used in amounts of from 2 to 10 %, preferably about 8%. The cosmetic agents of the invention have a mild care effect, they are therefore also particularly suitable for the care of sensitive skin and increase the resistance of healthy skin to acne and seborrhea.

The following examples illustrate the preparation of a preferred thioether, as well as some cosmetic preparations using alkyl thioethers η of polyalkylene glycols.

Example 1"

In a closed reaction vessel with a Temperature from 14o to l60 ° 0 and in the presence of a catalyst, such as sodium hydroxyil · (about 0.5 #) # one mole tertiary dodecyl mercaptan reacted with 12 INoI Kthylenoxyd. A viscous yellow colored water-soluble one is obtained Productive surface-like properties possesses and corresponds to the following formula »

^C 12 ^H 25 ^{S (CH} 2

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U92001

Example 2 t

For the production of the cosmetic preparations one proceeds according to, in the production of creams and Facial milk usual methods. The ingredients of a cream were as follows

Alkylthioether of a polyalkylene glycol t 8 # Oxyethylated lauryl ether t $ 1.5

Ceryl alcohol: 25 #

demineralized water: remaining amount

Example 3

Skin cream

Alkyl thioether of a polyalkylene glycol t 6 %

Stearic acid glyceride t 4 %

Vilwithine "ι 10 %

Cetyl alcohol: 1 %

Perhydrosqualene l. 4 %

demineralized water: remaining amount

Example 4

Skin cream

Alkyl thioether of a polyalkylene glycol: 10 %

oxyethylated lauryl ether ι 1.5 %

Cetyl alcohol - t 50 %

Protein soap t 0.5 #

Preservative plus water ι resti. lot

Example 5 I. 9 % Alkylthioether of polyethylene glycol t 2% Perhydrosqualene I. polyedoxylated cetyl alcoholOfl. ι ■ '■■ " stearin ι 7 » spermaceti I. 1 % iBopropyl t o. 6 * Steptunolamine I. 7 % Propylene glycol ,. 909810/074 $ IAD ORIGINAL

~ ⁵ ~

Zinc tearat preservatives and water

1.5 / ^

resti. lot

Example 6

Skin cream

Polyethylene glycol alkyl thioether, oxyethylated lauryl ether, cetyl alcohol
demineralized water

: 8 yy

: 1.5 %

: 25 each

: remaining quantity

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Claims (6)

U92001 claims 1.) Cosmetic product, especially cream or facial milk, characterized by a content of at least one alkyl thioether of a polyalkylene glycol the formula: “t RS- (CH ₂ - CH - O) _n H en in which R is an alkyl radical, preferably a branched alkyl radical with 2 to 18 carbon atoms, R ^{1 is} a hydrogen atom or a methyl group and η is an integer between 1 and 14. ' 2.) Cosmetic agent according to claim 1, characterized in that it is a tertiary alkylthioether Dodecylthioether of polyethylene glycol of the formula: Contains CIL ₅ (CH ₂ ) _n -S- (CH ₂ -CH ₂ O) _n H. 3.). Cosmetic agent according to claim 2, characterized in that that the tertiary dodecyl thioether of polyethylene glycol is in the form of an isomeric mixture. 4,) Cosmetic agent according to claims 2 and J thereby characterized in that the number η of the polyethylene glycol residues is approximately equal to 12. 5.) Cosmetic agent according to claims 1 to 4, characterized in that one as an alkylthioether. Polyalkylene glycols. purified product «with one Iron content used by less than 0.5 per mille will. 909810/07 4 5 bad original 6.) Cosmetic agent according to claims 1 to 5 *, characterized in that the content of alkyl thioether of a polyalkylene glycol is between 2 and 10 %, preferably about 8 % . 9098 10 / 074S