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DE1212082B - Verfahren zur Herstellung von 3, 11-Dioxo-20-tert.-amino-20-alkyl-4-pregnenverbindungen und Salzen derselben - Google Patents

Verfahren zur Herstellung von 3, 11-Dioxo-20-tert.-amino-20-alkyl-4-pregnenverbindungen und Salzen derselben

Info

Publication number
DE1212082B
DE1212082B DER35992A DER0035992A DE1212082B DE 1212082 B DE1212082 B DE 1212082B DE R35992 A DER35992 A DE R35992A DE R0035992 A DER0035992 A DE R0035992A DE 1212082 B DE1212082 B DE 1212082B
Authority
DE
Germany
Prior art keywords
methyl
dioxo
ecm
dimethylamino
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DER35992A
Other languages
German (de)
English (en)
Inventor
Dr-Ing Daniel Bertin
Dr Lucien Nedelec
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of DE1212082B publication Critical patent/DE1212082B/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DER35992A 1962-08-27 1963-08-27 Verfahren zur Herstellung von 3, 11-Dioxo-20-tert.-amino-20-alkyl-4-pregnenverbindungen und Salzen derselben Pending DE1212082B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR907856A FR1421231A (fr) 1962-08-27 1962-08-27 Nouveaux amino-stéroïdes et procédé de préparation

Publications (1)

Publication Number Publication Date
DE1212082B true DE1212082B (de) 1966-03-10

Family

ID=8785774

Family Applications (4)

Application Number Title Priority Date Filing Date
DER35992A Pending DE1212082B (de) 1962-08-27 1963-08-27 Verfahren zur Herstellung von 3, 11-Dioxo-20-tert.-amino-20-alkyl-4-pregnenverbindungen und Salzen derselben
DER35993A Pending DE1212083B (de) 1962-08-27 1963-08-27 Verfahren zur Herstellung von 20-tert.-Amino-20-alkyl-5alpha-pregnanverbindungen und Salzen derselben
DER35991A Pending DE1212081B (de) 1962-08-27 1963-08-27 Verfahren zur Herstellung von 11-Oxo-20-tert.-amino-20-alkyl-5beta-pregnanverbindungeund Salzen derselben
DER35990A Pending DE1212080B (de) 1962-08-27 1963-08-27 Verfahren zur Herstellung von 20-tert-Amino-20-alkyl-steroiden und Salzen derselben

Family Applications After (3)

Application Number Title Priority Date Filing Date
DER35993A Pending DE1212083B (de) 1962-08-27 1963-08-27 Verfahren zur Herstellung von 20-tert.-Amino-20-alkyl-5alpha-pregnanverbindungen und Salzen derselben
DER35991A Pending DE1212081B (de) 1962-08-27 1963-08-27 Verfahren zur Herstellung von 11-Oxo-20-tert.-amino-20-alkyl-5beta-pregnanverbindungeund Salzen derselben
DER35990A Pending DE1212080B (de) 1962-08-27 1963-08-27 Verfahren zur Herstellung von 20-tert-Amino-20-alkyl-steroiden und Salzen derselben

Country Status (6)

Country Link
BE (1) BE636641A (xx)
DE (4) DE1212082B (xx)
ES (1) ES290991A1 (xx)
FR (3) FR1421231A (xx)
GB (4) GB1025906A (xx)
NL (4) NL297133A (xx)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3013008A (en) * 1961-01-09 1961-12-12 Searle & Co N-substituted 20-aminopregnan-3-ols, esters thereof, and deta-derivatives corresponding

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3013008A (en) * 1961-01-09 1961-12-12 Searle & Co N-substituted 20-aminopregnan-3-ols, esters thereof, and deta-derivatives corresponding

Also Published As

Publication number Publication date
DE1212080B (de) 1966-03-10
GB1025908A (en) 1966-04-14
FR2374M (fr) 1964-04-03
GB1025906A (en) 1966-04-14
NL297131A (xx)
GB1025907A (en) 1966-04-14
FR1421231A (fr) 1965-12-17
BE636641A (xx)
NL123751C (xx)
NL297133A (xx)
GB1045644A (en) 1966-10-12
ES290991A1 (es) 1963-12-01
DE1212083B (de) 1966-03-10
NL297135A (xx)
DE1212081B (de) 1966-03-10
FR56F (fr) 1964-10-16

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