DE102023109898A1 - Medical guidewire with twisted core wire - Google Patents

Abstract

2.1. The invention relates to a medical guide wire with a core wire (3) extending from a proximal region (1) of the guide wire to a distal region (2) of the guide wire, which is formed from a wire material (4) twisted about its longitudinal axis (4L).2.2. According to the invention, the guide wire has a conductor element arrangement (5) which includes at least one electrically conductive and/or light-conducting and/or fluid-conducting conductor element (51) which extends from the proximal region (1) of the guide wire to the distal region (2) of the guide wire in a helical manner synchronously with the twisting of the core wire (3).2.3. Use in particular in medical endoscopy technology.

Description

The invention relates to a medical guide wire having a core wire extending from a proximal region of the guide wire to a distal region of the guide wire, which core wire is formed from a wire material twisted around its longitudinal axis.

Medical guide wires are known in many different designs for different areas of application in medical technology, especially in endoscopy, especially in connection with catheter instruments. The proximal area represents a rear area of the guide wire, which can typically be coupled to a user-operated control unit. The distal area represents a front area of the guide wire, with which the guide wire can typically be introduced into a human or animal tissue channel and in which a functional element can be located at a distal end area of the guide wire, e.g. a sensor element or a light source or a scissors, pliers or cutting tool, as required. In many applications it is also desired that the distal end area of the guide wire has a lower bending stiffness in at least one bending direction, alternatively in two bending directions or on all sides, than in the rest of the guide wire. The area of the guide wire between the proximal end area and the distal end area is also generally referred to as the shaft area.

In the type of guide wire considered here, the core wire is made of a wire material made of metal or plastic that is twisted about its longitudinal axis, i.e. it is twisted about its longitudinal axis so that, for example, in the case of a flat wire material, its side edges are wound in a helical manner. Depending on requirements, the twist can be uniform, i.e. with a winding pitch of its side edges that remains constant over its twisted length, or different in different sections with a continuous or abrupt transition from one winding pitch to the other.

A guide wire of the type mentioned above, in which the core wire is formed from a twisted flat wire material with a rectangular cross-section, is described in the patent specification US 5,313,967 revealed.

The patent specification DE 10 2017 200 077 A1 discloses a medical guide wire with a coil spring piece made of a flat wire material.

The invention is based on the technical problem of providing a medical guide wire of the type mentioned at the outset, which offers further functionalities and application possibilities compared to the above-mentioned prior art and can be manufactured with comparatively low manufacturing effort.

The invention solves this problem by providing a medical guide wire with the features of claim 1. Advantageous further developments of the invention are the subject of the subclaims, the wording of which is hereby made part of the description by reference. This includes in particular all embodiments of the invention that result from the combinations of features that are defined by the references in the subclaims.

The medical guide wire according to the invention contains at least one electrically conductive and/or light-conducting and/or fluid-conducting conductor element which extends from the proximal region of the guide wire to the distal region of the guide wire in a helical manner synchronously with the twisting of the core wire. The twisting of the core wire offers advantages in terms of the bending behavior of the guide wire, and the use of the twisted core wire offers advantages in terms of relatively low manufacturing costs. The presence of the conductor element results in correspondingly expanded application possibilities for the guide wire. The conductor element is advantageously adapted in its helical longitudinal course to the twisted course of the core wire.

For example, the conductor element in the electrically conductive version can be used to transmit an electrical signal and/or electrical energy between the distal and proximal areas of the guide wire, e.g. an electrical sensor signal from a sensor arranged in the distal guide wire area to the proximal guide wire area or electrical energy or an electrical control signal from the proximal guide wire area to an electrical functional element arranged in the distal guide wire area, such as an electrically controllable or actuatable scissors, forceps or cutting tool or an electrical light source.

In the light-conducting version, the conductor element can be used, for example, to transmit an optical control signal from the proximal area to the distal area of the guide wire or to transmit a sensor signal from the distal area of the guide wire to the proximal area. or to act as a light guide for a camera system.

In the fluid-conducting embodiment, the conductor element is hollow to form at least one lumen and can be used, for example, to supply a fluid from the proximal region to the distal region of the guide wire or to drain a fluid from the distal region of the guide wire to the proximal region.

In a further development of the invention, the wire material is a flat wire material with a polygonal cross-section. The use of such a flat wire material is generally associated with comparatively low manufacturing costs and offers functional advantages for corresponding applications. In use, the friction of the twisted core wire on the inside of an element surrounding the guide wire, such as a catheter tube, can be kept low, since the frictional contact in this case is limited to the helical side edges of the flat wire material and there is no larger, flat frictional contact. In alternative embodiments, a different type of wire material is used for the core wire, e.g. a round wire material, if this is sufficient or inexpensive for the application in question and/or offers advantages in terms of manufacturing technology.

In a further development of the invention, the wire material has a ratio of wire width to wire thickness of between 1:1 and 4:1. The wire width is the maximum cross-sectional dimension and the wire thickness is the minimum cross-sectional dimension of the wire material. It turns out that a ratio of wire width to wire thickness in this range between 1:1 and 4:1 for the twisted core wire is favorable for many guide wire applications. In alternative designs, a wire material with a ratio of wire width to wire thickness greater than 4:1 can also be used.

In a further development of the invention, the conductor element is inserted into an associated conductor receiving groove of the core wire. By inserting it into the conductor receiving groove, a flush or non-protruding course of the conductor element with the core wire can be achieved, if desired, i.e. in this case the conductor element does not protrude radially beyond the core wire. In alternative designs, the conductor element is arranged radially protruding on the outside of the core wire, whereby, depending on the implementation, it rests against the outside of the core wire with contact or has a certain, small distance from it.

In a further development of the invention, the conductor element is arranged on a broad side of the core wire. This placement of the conductor element has the advantage that the lateral extension of the twisted core wire can be kept relatively small and can be limited, for example, to the wire width of the wire material used for the core wire. In alternative embodiments, the conductor element is arranged on a narrow side of the core wire if this offers advantages for the application in question.

In one embodiment of the invention, the conductor element arrangement includes a first conductor element on a first broad side of the core wire and a second conductor element on a second broad side of the core wire. This measure allows two conductor elements to be arranged on the core wire without having to increase the lateral dimension of the twisted core wire, which can then be determined by the wire width of the wire material used and thus the distance between opposite narrow sides. In other embodiments, one or more conductor elements can be arranged on one or more narrow sides of the core wire in addition to or as an alternative to the conductor elements arranged on the broad side(s) of the core wire.

In a further development of the invention, the core wire has at least one flat side surface and at least one rounded side surface. This implementation is advantageous for applications in which the core wire is to have an at least partially rounded shape in cross-section. In this case, it may be preferable to arrange the conductor element on the flat side surface of the core wire. In alternative embodiments, the core wire can, for example, have a polygonal cross-section without rounded side surfaces or a circular or oval cross-section without flat side surfaces if this is advantageous for corresponding applications.

In a further development of the invention, the core wire and the conductor element arrangement are embedded in an embedding material from the proximal area of the guide wire to the distal area of the guide wire. The embedding material envelops the core wire and the conductor arrangement and secures these guide wire components in their mutual position without any other measures having to be taken for this purpose. In alternative embodiments, such embedding of the core wire and the conductor element arrangement from the proximal to the distal guide wire area is missing, whereby the conductor element(s) can be held to the core wire, for example, by an adhesive or welded connection.

In a further development of the invention, the guide wire has a sheath that surrounds the core wire and the conductor element arrangement from the proximal area of the guide wire to the distal area of the guide wire. The sheath can be used to secure the position of the conductor element(s) on the core wire. In addition, the sheath can fulfill other functions known per se, such as improving the sliding properties of the guide wire and/or electrically insulating the guide wire radially outwards. In alternative designs, the sheath is omitted if this is not necessary for the application in question or does not provide any advantages.

In one embodiment of the invention, a fluid guide lumen extending from the proximal region of the guide wire to the distal region of the guide wire is formed between the core wire and the sheathing tube. In this case, the sheathing tube also fulfills a fluid guide function together with the core wire. In the fluid guide volume, a fluid can be guided from the proximal to the distal guide wire region or from the distal to the proximal guide wire region. For such applications, a wire material with a width/thickness ratio of more than 4:1 can be advantageous in order to have a relatively large cross-section available for the fluid guide lumen. In alternative embodiments, such a fluid-conducting cavity between the core wire and the sheathing tube is missing, for example in cases where a gap between the core wire and the sheathing tube is filled with an embedding material.

In a further development of the invention, the guide wire includes a stiffening wire arrangement which includes at least one stiffening wire which extends from the proximal region of the guide wire to the distal region of the guide wire in a helical manner synchronously with the twisting of the core wire. The stiffening wire arrangement can be used to give the guide wire a desired bending behavior. The stiffening wire follows the twisting of the core wire, which can simplify production and keep the lateral dimension of the guide wire relatively small. In alternative embodiments, the guide wire is provided without such a stiffening wire arrangement.

In a further development of the invention, the core wire has a distal core wire section tapered to a round cross-section in a distal tip region of the guide wire. An electrical functional element is arranged at a distal end of the guide wire, to which the conductor element is guided. The distal tip region of the guide wire has a distal sheath that surrounds the electrical functional element, the conically tapered distal core wire section and the part of the conductor element running there. The conical taper to the round cross-section gives the distal core wire section a lower bending stiffness, regardless of direction, than the remaining, non-tapered section. The conical taper can be achieved by grinding, for example. The electrical functional element at the distal tip region fulfills a corresponding function for the guide wire, e.g. a sensor function or a wireless, electromagnetic control or tool function. The electronic functional element and the part of the conductor element running in the distal tip area of the guide wire are protected by the distal sheath, which can be a seamlessly embedded sheath or a hose-like surrounding sheath. In alternative designs, the guide wire is designed in a different way in the distal tip area, adapted to the respective application.

• 1 eine ausschnittweise perspektive Seitenansicht eines Führungsdrahtes mit verdrilltem Kerndraht aus rechteckigem Flachdrahtmaterial und mit Leiterelement,
• 2 eine Querschnittansicht längs einer Linie II-II von 1,
• 3 die Querschnittansicht von 2 für eine Führungsdrahtvariante mit zwei Leiterelementen,
• 4 die Seitenansicht von 1 für eine Variante mit einem verdrillten Kerndraht aus Runddrahtmaterial mit Leiteraufnahmenut,
• 5 die Querschnittansicht von 2 für die Variante von 4,
• 6 die Querschnittansicht von 5 für eine Variante mit zwei Leiteraufnahmenuten und Leiterelementen,
• 7 eine ausschnittweise Seitenansicht eines verdrillten Führungsdraht-Kerndrahtes aus rechteckigem Flachdrahtmaterial mit auf einen runden Querschnitt konisch abgeschliffenem distalem Endbereich,
• 8 die Seitenansicht von 7 für eine Variante mit zusätzlicher distaler Schraubenfederumhüllung,
• 9 die Querschnittansicht von 3 für eine Variante mit zusätzlichem Hüllschlauch,
• 10 die Querschnittansicht von 9 für eine Variante mit biegeweicherem Hüllschlauch,
• 11 die Querschnittansicht von 9 für eine Variante mit gerundeten Kerndraht-Schmalseiten,
• 12 die Querschnittansicht von 7 für eine Variante mit zusätzlichem Hüllschlauch,
• 13 die Querschnittansicht von 9 für eine Variante mit zusätzlicher Versteifungsdraht- und/oder zusätzlichen Leiterelementen,
• 14 die Querschnittansicht von 13 für eine Variante mit einbettender Umhüllung,
• 15 eine ausschnittweise Seitenansicht eines Führungsdrahtes mit dem Kerndraht von 7 und einem distalen elektrischen Bauteil,
• 16 eine ausschnittweise Seitenansicht eines Führungsdrahtes mit dem Kerndraht von 8, einem Hüllschlauch und einem Fluidführungslumen zwischen Kerndraht und Hüllschlauch und
• 17 eine Detailansicht eines Bereichs XVII von 16.

Advantageous embodiments of the invention are shown in the drawings. These and other embodiments of the invention are described in more detail below. Shown here:

• 1 a partial perspective side view of a guide wire with twisted core wire made of rectangular flat wire material and with conductor element,
• 2 a cross-sectional view along a line II-II of 1 ,
• 3 the cross-sectional view of 2 for a guide wire variant with two conductor elements,
• 4 the side view of 1 for a variant with a twisted core wire made of round wire material with conductor receiving groove,
• 5 the cross-sectional view of 2 for the variant of 4 ,
• 6 the cross-sectional view of 5 for a variant with two conductor receiving slots and conductor elements,
• 7 a partial side view of a twisted guide wire core wire made of rectangular flat wire material with a distal end region conically ground to a round cross-section,
• 8 the side view of 7 for a variant with additional distal coil spring sheath,
• 9 the cross-sectional view of 3 for a variant with additional sheathing tube,
• 10 the cross-sectional view of 9 for a variant with a more flexible sheath,
• 11 the cross-sectional view of 9 for a variant with rounded core wire narrow sides,
• 12 the cross-sectional view of 7 for a variant with additional sheathing tube,
• 13 the cross-sectional view of 9 for a variant with additional stiffening wire and/or additional conductor elements,
• 14 the cross-sectional view of 13 for a variant with embedding casing,
• 15 a partial side view of a guide wire with the core wire of 7 and a distal electrical component,
• 16 a partial side view of a guide wire with the core wire of 8 , a sheath tube and a fluid guide lumen between the core wire and the sheath tube and
• 17 a detailed view of an area XVII of 16 .

The figures schematically illustrate various advantageous embodiments of the medical guide wire according to the invention with the components of interest here. As can be seen therefrom, the guide wire includes a core wire 3 extending from a proximal region 1 to a distal region 2 of the guide wire, which is formed from a wire material 4 that is twisted about its longitudinal axis 4L. The guide wire also has a conductor element arrangement 5 that includes at least one electrically conductive and/or light-conducting and/or fluid-conducting conductor element 5 ₁ that extends helically from the proximal guide wire region 1 to the distal guide wire region 2, the helical course of the conductor element 5 ₁ being synchronous with the twisted course of the core wire 3. In other words, the helical course of the conductor element 5 ₁ corresponds to the helical course of an imaginary line which, in the untwisted state, runs purely axially along the outside of the wire material 4 after it has been twisted.

In corresponding embodiments, the wire material 4 is a flat wire material 4 _F with a polygonal cross-section. In the 1 to 3, 7 to 11 and 13 to 17 Associated embodiments can be seen in which the wire material 4 is specifically a flat wire material 4 _F with a substantially rectangular cross-section with two opposite broad sides 3 _B and narrow sides 3s.

In corresponding implementations, the wire material 4 has a ratio of wire width B _D , ie maximum transverse dimension, to wire thickness D _D , ie minimum transverse dimension, between 1:1 and 4:1. In the examples shown with the flat wire material 4 _F with a rectangular cross-section, this ratio is in the range from slightly over 1:1 to approximately 3:1. A ratio of 1:1 corresponds to a square wire cross-section.

The 4 to 6 and 12 illustrate embodiments in which the wire material 4 of the twisted core wire 3 is a round wire material 4 _R with a substantially circular cross-section, ie the ratio of wire width B _D to wire thickness D _D is 1:1.

In corresponding embodiments, the conductor element 5 ₁ is inserted into an associated conductor receiving groove 6 of the core wire 3. Such embodiments are shown in the 4 to 6 and 12 In the example of 4 and 5 the core wire 3 has a single conductor receiving groove 6, into which an associated conductor element 5 ₁ is inserted. In the examples of 6 and 12 the core wire 3 has two diametrically opposed conductor receiving grooves 6, into each of which a conductor element 5 ₁ , 5 ₂ of the conductor element arrangement 5, which in this case consists of the two conductor elements 5 ₁ , 5 _2, is inserted. It is understood that the respective conductor receiving groove 6 on the outer circumference of the core wire 3 runs helically in accordance with the twisting of the core wire 3, as can be seen for example from 4 visible.

In the examples of the 4 to 6 and 12 the conductor element 5 ₁ , 5 ₂ inserted into the respective conductor receiving groove 6 is flush with the outside of the core wire 3 without protruding radially outwards beyond it. In alternative embodiments, it can be provided that at least one of the conductor elements 5 ₁ , 5 ₂ protrudes radially outwards beyond the core wire 3.

In the examples shown, the 4 to 6 and 12 the respective conductor receiving groove 6 is introduced into the round wire material 4 _R of the core wire 3. In alternative embodiments not shown, the respective conductor receiving groove 6 of the core wire 3 is introduced into a different wire material 4, e.g. into a flat wire material 4 _F with a polygonal cross-section, as in the examples of 1 to 3, 7 to 11 and 13 to 17 specifically used as rectangular wire material 4.

In corresponding embodiments, the conductor element 5 ₁ is arranged on a broad side 3 _B of the core wire 3. Related embodiments are shown in the 1 to 3, 9 to 11 and 13 to 15 This positioning increases the conductor element 5 ₁ does not have the lateral dimension of the twisted core wire 3 determined by the wire width B _D when using rectangular flat wire material 4 _{F. The wire width B D corresponds to the distance between the opposite narrow sides 3s of the flat wire material 4 F in the} case of the rectangular flat wire material 4 _F.

In corresponding embodiments, the conductor element arrangement 5 includes a first conductor element 5 ₁ on a first broad side 3 _B of the core wire 3 and a second conductor element 5 ₂ on a second broad side 3 _B of the core wire 3. Related embodiments are shown in the 3 and 9 to 11 illustrated.

In corresponding embodiments, the core wire 3 and the conductor element arrangement 5 are embedded in an embedding material 7 from the proximal region 1 of the guide wire to the distal region 2 thereof. In this case, the embedding material 7 forms a sheath that preferably embeds the core wire 3 and the conductor element arrangement 5 without any cavities. An associated embodiment is shown in 14 shown. The embedding material 7 secures the conductor element arrangement 5 in its position on the twisted core wire 3. Designs with such an embedding material 7 can be manufactured, for example, by extrusion, which keeps the manufacturing effort low.

In the examples of the 13 and 14 the conductor element arrangement 5 includes two conductor elements 5 ₁ , 5 ₃ , which are both arranged on a common broad side 3 _B of the core wire 3. In the case shown, the two conductor elements 5 ₁ , 5 ₃ are arranged radially adjacent to one another.

In corresponding embodiments, the guide wire includes a sheath tube 8 which surrounds the core wire 3 and the conductor element arrangement 5 from the proximal region 1 of the guide wire to the distal region 2 thereof. Related embodiments are shown in the 9 to 13 and 15 to 17 illustrated. The sheath tube 8 can secure the conductor element arrangement 5 in its position on the twisted core wire 3 and, as required, fulfill further functions, such as improving the sliding properties of the guide wire and electrically insulating the guide wire radially outward.

In corresponding embodiments, a fluid guide lumen 9 extending from the proximal region 1 of the guide wire to the distal region 2 thereof is formed between the core wire 3 and the sheath tube 8. Related embodiments are shown in the 9 to 11, 13 and 16 and 17. The fluid guide lumen 9 can be implemented as a single piece or as a multi-piece piece consisting of several individual lumens. Depending on requirements, a particular fluid can be guided through the fluid guide lumen 9 from the proximal guide wire region 1 to the distal guide wire region 2 or from the distal guide wire region 2 to the proximal guide wire region 1, for example water, a fluid containing medication, a tissue fluid or a working fluid. In this application, it can be advantageous to select a relatively large width/thickness ratio of more than 4:1 for the core wire 3 in order to achieve a relatively large cross-section of the fluid guide lumen 9 for a given lateral dimension of the guide wire.

In corresponding embodiments, the guide wire includes a stiffening wire arrangement 10 or additional conductor elements of the conductor element arrangement 5, which comprises at least one stiffening wire 10 ₁ or additional conductor element extending from the proximal guide wire region 1 to the distal guide wire region 2, like the respective conductor element 5 ₁ with a helical course synchronous to the twisting of the core wire 3. Related embodiments are described in the 13 and 14 shown. In these examples, the stiffening wire 10 ₁ or the at least one further conductor element of the conductor element arrangement 5 consists of a stranded wire which is formed from a central strand and six surrounding strands. When used as at least one further conductor element of the conductor element arrangement 5, depending on the design, all strands together can form an associated, multi-core conductor element or each strand can individually form its own respective conductor element. It is understood that the stiffening wire 10 ₁ or the at least one further conductor element of the conductor element arrangement 5 can have any other conventional wire structure as required.

In the examples of 13 and 14 the stiffening wire 10 ₁ or the at least one further conductor element of the conductor element arrangement 5 is arranged on a broad side 3 _B of the flat wire material 4 _F used there, specifically on the broad side 3 _B that faces away from the conductor elements 5 ₁ and 5 ₃ of the conductor element arrangement 5. The stiffening wire arrangement 10 can be used to set a desired bending behavior for the guide wire in the corresponding guide wire section if required.

In corresponding embodiments, the core wire 3 has a distal core wire section 3j tapered to a round cross-section in a distal tip region 2s of the guide wire. 7, 8 and 15 to 17 show such embodiments. At a distal end 2 _E of the guide wire, in the embodiment game of 15 an electrical functional element 11 is arranged, to which the conductor element 5 ₁ is guided. The distal tip region 2s of the guide wire has a distal sheath 12 which surrounds the electrical functional element 11, the conically tapered distal core wire section 3j and the part of the conductor element 5 ₁ running there. In the example shown, the sheath 12 is formed from an embedding material in which the electrical functional element 11, the conically tapered core wire section 3j and the conductor element 5 ₁ are embedded in this guide wire section. Alternatively, the distal sheath 12 can also be realized, for example, by a helical spring sheath 13, as in the embodiments of the 8 and 16 and 17. In the embodiment of the 16 and 17 the sheath tube 8 also extends into the distal tip region 2s of the guide wire and functions there together with the coil spring sheath 13 as a distal sheath, wherein the coil spring sheath 13 is surrounded radially outwardly by the sheath tube 8.

In all cases shown, the respective conductor element 5 ₁ , 5 ₂ is designed to be electrically conductive and/or light-conducting and/or fluid-conducting, depending on the application. Accordingly, the respective conductor element 5 ₁ , 5 ₂ consists of an electrically conductive and/or light-conducting material and/or a hollow material with a fluid-conducting cavity.

As the embodiments shown and the other embodiments explained above make clear, the invention advantageously provides a medical guide wire with a twisted core wire, which can be manufactured relatively easily and has extended functionalities due to the presence of the conductor element arrangement.

QUOTES INCLUDED IN THE DESCRIPTION

This list of documents listed by the applicant was generated automatically and is included solely for the better information of the reader. The list is not part of the German patent or utility model application. The DPMA accepts no liability for any errors or omissions.

Cited patent literature

• US 5313967 [0004]
• DE 102017200077 A1 [0005]

Claims (12)

Medical guide wire with - a core wire (3) extending from a proximal region (1) of the guide wire to a distal region (2) of the guide wire, which is formed from a wire material (4) twisted about its longitudinal axis (4L), characterized by - a conductor element arrangement (5) which includes at least one electrically conductive and/or light-conducting and/or fluid-conducting conductor element (5 ₁ ) which extends from the proximal region (1) of the guide wire to the distal region (2) of the guide wire in a helical manner synchronously with the twisting of the core wire (3). Medical guide wire according to claim 1 , further characterized in that the wire material (4) is a flat wire material (4 _F ) with a polygonal cross-section. Medical guide wire according to claim 1 or 2 , further characterized in that the wire material (4) has a ratio of wire width (B _D ) to wire thickness (D _D ) between 1:1 and 4:1. Medical guide wire according to one of the Claims 1 until 3 , further characterized in that the conductor element (5 ₁ ) is inserted into an associated conductor receiving groove (6) of the core wire (3). Medical guide wire according to one of the Claims 1 until 4 , further characterized in that the conductor element (5 ₁ ) is arranged on a broad side (3 _B ) of the core wire (3). Medical guide wire according to claim 5 , further characterized in that the conductor element arrangement (5) includes a first conductor element (5 ₁ ) on a first broad side (3 _B ) of the core wire (3) and a second conductor element (5 ₂ ) on a second broad side (3 _B ) of the core wire (3). Medical guide wire according to one of the Claims 1 until 6 , further characterized in that the core wire (3) has at least one flat side surface (3 _E ) and at least one rounded side surface (3 _R ). Medical guide wire according to one of the Claims 1 until 7 , further characterized in that the core wire (3) and the conductor element arrangement (5) are embedded in an embedding material (7) from the proximal region (1) of the guide wire to the distal region (2) of the guide wire. Medical guide wire according to one of the Claims 1 until 8 , further characterized by a sheath tube (8) which surrounds the core wire (3) and the conductor element arrangement (5) from the proximal region (1) of the guide wire to the distal region (2) of the guide wire. Medical guide wire according to claim 9 , further characterized in that a fluid guide lumen (9) extending from the proximal region (1) of the guide wire to the distal region (2) of the guide wire is formed between the core wire (3) and the sheath tube (8). Medical guide wire according to one of the Claims 1 until 10 , further characterized by a stiffening wire arrangement (10) which includes at least one stiffening wire (10 ₁ ) which extends from the proximal region (1) of the guide wire to the distal region (2) of the guide wire in a helical manner synchronously with the twisting of the core wire (3). Medical guide wire according to one of the Claims 1 until 11 , further characterized in that - the core wire (3) has a distal core wire section (3j) tapered to a round cross-section in a distal tip region (2s) of the guide wire, - an electrical functional element (11) is arranged at a distal end ( _2E ) of the guide wire, to which the conductor element ( ₅₁ ) is guided, and - the distal tip region (2s) of the guide wire has a distal sheath (12) which surrounds the electrical functional element (11), the conically tapered distal core wire section (3j) and the part of the conductor element ( ₅₁ ) running there.