DE102019007042A1 - Containers and methods for transporting sterile goods and for removal in an isolator, as well as a combination of isolator and docked container - Google Patents

Abstract

The invention relates to a container (10) for transporting sterile goods and for removing the goods in a clean room (12) of an isolator (14), with an opening (26) and a container-side part (18) of a rapid transfer port System which comprises a container lid (20) for closing the opening and means for docking the container on a complementary isolator-side part (16) of the rapid transfer port system, as well as with a material receptacle (30) movable along a linear guide (34) . According to the invention, at least one ferromagnetic and / or permanent magnetic body (62) is mounted on the crop receptacle (30), which is arranged in the vicinity of a circumferential wall (22) of the container and by means of at least one outside of the container linearly moved along the circumferential wall and with magnetic forces of attraction magnets (64) or ferromagnets acting on the body (62) in a contactless manner through the circumferential wall can be moved parallel to the linear guide in order to move the crop receptacle at least partially into the clean room without interfering with the isolator.

Description

The invention relates to a container according to the preamble of claim 1, a combination of an insulator and such a container docked on the insulator according to the preamble of claim 12, and a method according to the preamble of claim 14.

In the pharmaceutical industry and in laboratories, isolators that enclose a clean room are often required, the term isolator in the context of this patent application also being intended to include RABS systems.

In order to feed sterile goods into the interior of an isolator, a so-called Rapid Transfer Port (RTP) system is usually used, through which the goods contained in the sterile interior of a container are channeled into the isolator.

The sterile material can be, for example, rubber or plastic stoppers for vials or infusion bottles, which are cleaned and sterilized outside the isolator and, after being placed in the isolator, are fed to a machine for closing the vials or infusion bottles inside the clean room. The cleaning and sterilization of such goods can take place in a treatment device, such as that in the EP 2 823 828 A1 of the applicant is described. The sterile goods can, however, also be exchangeable or format parts that are to be installed in the machines, for example, when the format is changed within the clean room.

In the first-mentioned case, the cleaned and sterilized items can be transferred directly from a treatment container used in the treatment device to the isolator. In the latter case, the container with the pre-cleaned material is moved through an autoclave during transport to the isolator in order to sterilize the material inside the container. The container has an opening through which the material is introduced into the container and removed from the container.

The RTP system is used to transfer the sterile material from the sterile interior of the container to the sterile clean room of the isolator without contact with a non-sterile environment. The RTP system comprises a container-side part attached to the opening of the container, which is usually referred to as the beta part, and a complementary isolator-side part attached to the insulator, which is usually referred to as the alpha part. Before the goods are transferred, the container with the container-side part is docked or mechanically coupled to the isolator-side part.

The container-side part comprises an annular flange arranged in front of the opening of the container with an inserted seal, a container lid which tightly closes the opening during transport, and docking means for docking on the isolator-side part. The isolator-side part comprises a port opening which is surrounded by an annular flange with an inserted seal, a port door which tightly closes the port opening and can only be opened when the container is docked, and docking means complementary to the docking means of the container, which on the one hand ensure mechanical locking of the two ring flanges and, on the other hand, mechanical locking of the container lid with the port door. Where the container can be rotated around the central axis of the port opening in the docked state, this can be done, for example, by rotating the container.

When the closure cover is locked with the port door, opposite non-sterile surfaces of the closure cover and the port door are pressed against one another in a sealing manner or are enclosed tightly between the port door and the closure cover. The port door and the container lid are then moved together in the locked state into an open position inside the isolator in order to release the opening and the port opening for transferring the sterile material from the container into the clean room. In RTP systems with clean room operation of the port door, an operator grabs an operating handle of the port door by means of a glove grip inside the clean room in order to move it into the open position in which it is usually located to the side of the port opening. In RTP systems with external operation of the port door, the operator outside of the clean room actuates a mechanism in the wall of the isolator that moves the port door into the open position. After the removal of the goods from the container, the port door and the container lid are moved back together again into a closed position in order to first close the opening and the port opening, then to unlock the two ring flanges as well as the closure lid and the port door and finally the container by unlocking and Separate the two parts of the RTP system from the isolator to undock and move away.

The DE 102016001027 A1 and the WO 2017/129362 A1 of the applicant already disclose a container, a combination and a method of the type mentioned at the beginning. There, the material receptacle consists of a perforated basket which is movable in relation to the container and which receives a pourable material. During transport, the basket is in a transport position inside the closed container. To remove the goods, the basket can be moved along a linear guide into a removal position in which it is partially through the Opening protrudes into the clean room. This process is carried out by an operator gripping a handle of the basket by means of glove engagement from the clean room and pulling the basket out of the container.

A container with a pull-out receptacle for individual objects, such as spare parts, with an insert on rails for placing the objects, is available at http://www.castus.pro/en/gamma-equipment/drawer-and-railsystem/. Here, too, an operator must grasp the insert from the clean room and pull it out of the container in order to remove the objects.

However, since the port door protrudes relatively far into the clean room because of the container lid locked with the port door, it is difficult or even impossible for an operator to grasp the material pick-up by means of a glove grip over the open port door and to pull it inwards into the clean room . to move all the way back into the container. This means that in RTP systems with clean room operation of the port door, two glove interventions are required on opposite sides next to the RTP, one to open and close the port door locked with the container lid and the other to pull out or move back the goods pick-up after the Removal of the goods. This in turn leads to an increase in the space required by these RTP systems. In addition, glove interventions in RTP systems should be avoided as far as possible.

Due to the manual movement of the goods pick-up by means of a glove, the degree of automation is also low and the time required to remove the goods is high.

Starting from this, the invention is based on the object of improving a container, a combination and a method of the type mentioned at the outset so that in RTP systems the number of glove interventions can be kept as small as possible and a higher degree of automation and less time required the removal of the goods are achievable.

To achieve this object, the features in the characterizing part of claims 1, 12 and 14 are proposed according to the invention.

Thereafter, at least one ferromagnetic and / or permanent magnetic body is mounted on the material receptacle, which is arranged in the vicinity of a peripheral wall of the container and acts on the body in a contactless manner by means of at least one outside of the container moved linearly along the peripheral wall and with magnetic forces of attraction through the peripheral wall Magnets or ferromagnets can be moved or moved parallel to the linear guide.

If the ferromagnetic and / or permanent magnetic body and the magnet and / or ferromagnet are opposite each other on both sides of the peripheral wall in such a way that they attract each other, a state of equilibrium is established in which the magnetic field lines between the body and the magnet are aligned perpendicular to the peripheral wall . If the state of equilibrium is disturbed, e.g. by moving the magnet linearly away from the body along the circumferential wall, the magnetic field lines bend. As a result, a driving force acts on the body in the same direction, which tends to restore equilibrium. This driving force has the effect that the body is moved synchronously with the magnet if the magnetic force of attraction is large enough to overcome frictional forces counteracting the movement and to ensure a stable magnetic coupling. The latter is achieved by maximizing the magnetic attraction force as much as possible and minimizing the spacing as much as possible.

Due to the combination of features according to the invention, the material pick-up can be moved from the transport position into the removal position and back into the transport position by an operator located outside the isolator without having to intervene in the clean room. As a result, only one glove intervention is required for RTP systems with clean room operation of the port door. In addition, the time required to remove the goods can be reduced and the degree of automation increased by using a stepper motor or a pneumatic or hydraulic cylinder, if necessary, to move the at least one magnet or ferromagnet along the outside of the container.

A preferred embodiment of the invention provides that in a container with two opposite ends and a generally constant container cross-section between the ends, as is customary for the transport of sterile material to an RTP system, the opening is at one end and the magnetic one Body is arranged near the other end when the Gutaufnahme is in the transport position. In this way, the material receptacle can be moved particularly far out of the container and into the clean room in its removal position by moving the magnetic body along the linear guide up to the vicinity of the opening.

According to a preferred embodiment of the invention, the peripheral wall of the container is made of non-magnetic material, the one undisturbed transmission of the magnetic forces of attraction through the wall and thus the moving of the body by the magnetic forces. In principle, the peripheral wall can consist of plastic or metal. It is preferably made of non-magnetic austenitic stainless steel, as this is very easy to sterilize.

A maximum force of attraction and thus also a maximum driving force at relatively low costs are achieved if, according to an advantageous embodiment of the invention, the at least one magnet and / or the at least one ferromagnetic and / or permanent magnetic body is a rare earth magnet, preferably a neodymium (NdFeB ) Magnets, since neodymium magnets have very large magnetic forces of attraction and are now available relatively inexpensively. Since the container with the material receptacle and the material is usually sterilized in an autoclave, temperatures of 120 ° C. being exceeded in most cases, it is advantageous to use Nedodymium magnets with the designation SH, UH or EH.

In principle, instead of a permanent magnet, an electromagnet can also be used as the magnet, with which very large magnetic attraction forces can also be achieved.

To achieve great forces of attraction, both the at least one magnet and / or the at least one ferromagnetic and / or permanent magnetic body can advantageously comprise one or more pot magnets or yoke magnets with a ferromagnetic pot or yoke that has the magnetic field lines on the wall facing away from the circumferential wall Side of the magnet or body deflects to the side adjacent to the peripheral wall.

Since steam is usually fed into the interior of the container during the sterilization of the goods, a further preferred embodiment of the invention provides for the at least one body to be provided with a shell or coating made of a non-rusting material. The body is preferably encased in a thin shell made of stainless steel sheet, which is easier to achieve with a ferromagnetic body, since the arc is not deflected by magnetic field lines during arc welding. A magnetic body, on the other hand, can be chrome-plated or nickel-plated, for example, in order to avoid oxidation and thus also contamination of the goods in the container.

On the other hand, it is advantageous to minimize the frictional forces counteracting the movement of the material receptacle by moving the material receptacle according to a further advantageous embodiment on rollers along the linear guide and the ferromagnetic and / or permanent magnetic body being carried by the material receptacle and not itself is supported against the peripheral wall of the container or the linear guide.

In order to prevent material abrasion caused by friction and thus a possible contamination of the sterile goods in the container, the at least one body is advantageously always at a small distance from the peripheral wall during the movement along the linear guide, so that there is a small distance between its inside and an opposite surface of the body There is an air gap. This air gap preferably has a thickness of at least 0.5 mm and at most 3 mm in order to keep the distance between the magnet and the body as small as possible and to ensure a stable magnetic coupling during movement.

In order to avoid scratches on the outside of the peripheral wall during use, there should also be a small air gap between the at least one magnet outside the container and the outside of the peripheral wall. Alternatively, however, the magnet could also be provided with a thin friction-reducing layer, e.g. made of PTFE, on its side facing the peripheral wall.

In order to minimize the size and weight of the at least one body without a corresponding decrease in the magnetic forces of attraction, the body advantageously has, on its side facing the peripheral wall, a surface shape adapted to the cross-sectional shape of the peripheral wall, which in the case of a generally cylindrical container has an arcuate cross-section with a corresponding radius of curvature. If the body contains a plurality of permanent magnets, these are preferably arranged along an arc of a circle on the side of the body adjacent to the peripheral wall.

In principle, a single large rare earth permanent magnet, preferably a neodymium magnet, can be used as a magnet on the outside of the container, opposite which a single ferromagnetic and / or permanent magnetic body lies opposite inside the container, e.g. in the first-mentioned case a single larger body made of iron or a ferrous material or a single large permanent magnet, expediently either a rare earth or ferrite magnet.

However, it has been found that the weight of the magnet and / or body can be reduced without impairing the magnetic coupling by adding a plurality of disk-shaped or plate-shaped permanent magnets in the circumferential direction on the outside of the container arranged next to one another and / or arranged one behind the other in the direction of movement, which are expediently opposite a single ferromagnetic body or a plurality of permanent magnetic bodies in the interior of the container, expediently a corresponding number of disk-shaped or plate-shaped permanent magnets. In the last-mentioned case, the arrangement and magnetization of the opposing permanent magnets are chosen so that the north poles facing the circumferential wall inside the container are opposite the south poles facing the circumferential wall on the outside of the container. Disc-shaped or plate-shaped permanent magnets are referred to here as magnets whose thickness is less than half the diameter or less than half the side dimensions of the magnet in a plane parallel to the peripheral wall.

In particular where the item receptacle has a flat support surface for receiving individual objects, the at least one body is advantageously arranged below the item support, so that more space is available for the item above the support surface. In this case, the at least one magnet or ferromagnet can then be displaced underneath the container. However, the body can also be arranged above the material receptacle and the magnet or ferromagnet can be displaced above the container.

According to a further advantageous embodiment of the invention, the combination of insulator and docked container comprises a table or carriage which carries the container and which is provided with a linear guide for the magnet. In principle, the outside of the peripheral wall can also serve as a linear guide.

In order to ensure a constant distance between the body and the magnet along the path of movement of the item receptacle and the magnet, the at least one magnet is preferably displaceable along a linear guide of the table or trolley, whereby the movement of the magnet is expedient in the transport and removal position of the item receptacle is limited by stops.

Where the wall of the insulator is not transparent, it is not easily possible for the operator to determine without looking through a window into the clean room whether the at least one body is carried along inside the container during the linear movement of the at least one magnet , or not. In order to enable such a detection from the outside, a preferred embodiment of the invention provides to make the force of attraction between the body and the magnet so great that the magnet adheres to the outside of the container when the magnet inside the container is opposite the body . If there is no ferromagnetic or permanent magnetic material in front of and behind the body in the direction of movement, the magnet moves away from the peripheral wall. This movement is visible to the operator and indicates that the magnetic coupling is no longer present. Adhesion of the magnet to the peripheral wall is also advantageous because this ensures that the distance between the magnet and the body is always constant during the linear movement.

• Die 1a bis 1d zeigen perspektivische Ansichten eines erfindungsgemäßen Behälters sowie eines Ablagetischs, wobei 1a und 1b den Behälter mit Behälterdeckel und 1c und 1d den Behältermit ohne Behälterdeckel zeigen;
• die 2a und 2b zeigen vergrößerte perspektivische Ansichten des Behälters und des Ablagetischs ähnlich 1c und 1d;
• die 3a und 3b zeigen vergrößerte Seitenansichten des Behälters und des Ablagetischs entsprechend 1c und 1d;
• 4 zeigt eine vergrößerte Querschnittsansicht des Behälters und eines Teils des Ablagetischs entlang der Linie IV-IV der 3a;
• 5a zeigt eine vergrößerte Längsschnittansicht des Behälters auf dem Ablagetisch sowie eines Teils eines Isolators nach dem Andocken eines behälterseitigen Teils eines RTP-Systems an einen isolatorseitigen Teil, wobei sich eine Gutaufnahme des Behälters in einer Transportstellung befindet;
• 5b zeigt eine entsprechende Längsschnittansicht, jedoch nach dem Öffnen einer Porttür und des Behälterdeckels des RTP-Systems, wobei sich die Gutaufnahme in einer Entnahmestellung befindet;
• 6 zeigt eine vergrößerte Querschnittsansicht des Details VI in 4 gemäß einem ersten Ausführungsbeispiel;
• 7 zeigt eine vergrößerte Querschnittsansicht des Details VI in 4 gemäß einem zweiten Ausführungsbeispiel;
• 8 zeigt eine vergrößerte Querschnittsansicht des Details VI in 4 gemäß einem dritten Ausführungsbeispiel;
• 9 zeigt eine vergrößerte Querschnittsansicht des Details VI in 4 gemäß einem vierten Ausführungsbeispiel;
• 10 zeigt eine vergrößerte Querschnittsansicht des Details VI in 4 gemäß einem fünften Ausführungsbeispiel;
• 11 zeigt eine vergrößerte Querschnittsansicht des Details VI in 4 gemäß einem sechsten Ausführungsbeispiel.

The invention is explained in more detail below with reference to several exemplary embodiments shown in the drawing.

• The 1a to 1d show perspective views of a container according to the invention and a storage table, wherein 1a and 1b the container with container lid and 1c and 1d show the container with no container lid;
• the 2a and 2 B 9 similarly show enlarged perspective views of the bin and the support table 1c and 1d ;
• the 3a and 3b show enlarged side views of the bin and the storage table, respectively 1c and 1d ;
• 4th FIG. 14 is an enlarged cross-sectional view of the container and part of the storage table taken along line IV-IV of FIG 3a ;
• 5a shows an enlarged longitudinal sectional view of the container on the storage table as well as part of an isolator after docking of a container-side part of an RTP system to an isolator-side part, with an item receptacle of the container being in a transport position;
• 5b shows a corresponding longitudinal sectional view, but after opening a port door and the container lid of the RTP system, with the product receptacle being in a removal position;
• 6th shows an enlarged cross-sectional view of detail VI in FIG 4th according to a first embodiment;
• 7th shows an enlarged cross-sectional view of detail VI in FIG 4th according to a second embodiment;
• 8th shows an enlarged cross-sectional view of detail VI in FIG 4th according to a third embodiment;
• 9 shows an enlarged cross-sectional view of detail VI in FIG 4th according to a fourth embodiment;
• 10 shows an enlarged cross-sectional view of detail VI in FIG 4th according to a fifth embodiment;
• 11 shows an enlarged cross-sectional view of detail VI in FIG 4th according to a sixth embodiment.

The one in the 1 to 9 illustrated container according to the invention 10 is used for the transport and sterilization of goods, in the present case individual objects, such as exchange or format parts for machines or devices within a clean room 12th an isolator 14th , such as syringe filling machines or machines (not shown) for filling and closing infusion bottles or vials. The sterilization of the previously in the container 10 brought in goods takes place inside the container 10 by, for example, adding superheated steam to the container in an autoclave 10 is fed. After that the container 10 with the sterile goods to the isolator 14th transported to the container 10 on the isolator 14th to dock and the goods in the clean room 12th bring in.

To during transport to the isolator 14th and when docking to the isolator 14th any contamination of the sterile material in the container 10 to prevent are the isolator 14th and the container 10 equipped with a Rapid Transfer Port (RTP) system. Here is the isolator 14th with an insulator-side part also known as the alpha part 16 of the RTP system while the container 10 with a complementary part on the container side, also known as the beta part 18th of the RTP system is provided. A suitable rapid transfer port (RTP) system is offered by Getinge-LaCalhene, for example.

As best in 1 shown, owns the container 10 a generally cylindrical peripheral wall 22nd and is at one end by a flat end wall 24 closed while he was at the other end with an opening 26th is provided through which the goods in the container 10 introduced and out of the container 10 can be taken. The opening 26th is when the container is transported through a container lid 20th locked. At least the perimeter wall 22nd consists of an austenitic stainless steel, e.g. non-magnetic V2A steel. The opening cross-section of the opening 26th corresponds essentially to the inner cross-section of the peripheral wall 22nd . The container 10 is four-legged 28 provided, of which a pair near the end wall 24 and near the opening 26th is arranged.

On the front wall 24 can the container 10 have a media connection (not shown) with a filter through which superheated steam for sterilization of the goods into the interior of the closed container 10 can be fed.

The container is used for transporting and removing the goods 10 with a good recording 30th on which the goods can be placed. In a transport position ( 2a and 5a) is the good pick-up 30th completely inside the container 10 . With the container lid open 20th can take up the good 30th along a to the longitudinal central axis 32 of the container 10 parallel linear guide 34 be moved into a removal position in which they are partially through the opening 26th from the container 10 survives.

The Gutaufnahme shown in the drawing 30th consists essentially of a flat plate 36 that is slightly below the longitudinal central axis 32 is arranged with its two opposite edges 38 down along the peripheral wall 22nd are bent. On each of the two edges 38 are four pairs of rotatable rollers 40 appropriate. One role each 40 each pair of rollers lies from above or below against a narrow side of two guide rails 42 the linear guide 34 and rolls off on this. The parallel guide rails 42 are with one of their broadsides on the inward over the peripheral wall 22nd protruding ends of the legs 28 attached.

As best in 5a and 5b shown, includes the beta part 18th of the Rapid Transfer Port (RTP) system 26th surrounding, with an end flange 44 the perimeter wall 22nd screwed ring flange 46 , one in the ring flange 46 inserted ring seal 48 as well as the container lid 20th , which in the closed state with an outer conical peripheral surface sealingly against a complementary inner conical peripheral surface of the ring seal 48 is pressed to the opening 26th hermetically sealed during transport and during sterilization of the goods.

As best in 5a and 5b shown, includes the alpha part 16 of the Rapid Transfer Port (RTP) system a mounting flange 50 that is rigid with a boundary wall 52 of the isolator 14th is connected and surrounds a port opening (not visible) which is circular in outline, one in relation to the mounting flange 50 rotatable ring flange 54 , as well as one in the ring flange 54 inserted ring seal (not visible). The alpha part 16 further comprises a pivotable on the mounting flange 50 mounted port door 56 with a circular outline.

The alpha part 16 and the beta part 18th also include complementary locking devices (not visible) in place when the container is docked 10 on the one hand for a mutual locking of the two ring flanges 54 and 46 of the alpha Part 16 or the beta part 18th and on the other hand for a mutual locking of the container lid 20th and the port door 56 to care. This on the one hand becomes the container 10 on the isolator 14th fixed and on the other hand the opposite non-sterile surfaces of the two ring flanges 54 and 46 one hand as well as the port door 56 and the container lid 20th on the other hand, brought into contact with one another and pressed tightly against one another.

To the container 10 after sterilization of the goods on the isolator 14th dock and the goods in the isolator 14th to feed, the container 10 first to the isolator 14th transported ( 1a) where he is on the outside of the insulator 14th with its four legs 28 on a table 58 is turned off ( 1b) . The height of the table 58 , whose legs 60 can be provided with rollers (not shown) is at the height of the isolator-side alpha part 16 of the rapid transfer port system. When docking, the locking devices of the alpha and beta part 16 , 18th engaged with each other and the container 10 by turning the ring flange 54 on the isolator 14th fixed.

Where instead of the ring flange 54 the container 10 is rotated around the central axis of the port opening for docking, is the crop pick-up 30th provided with brackets or other fastening means to assist in rotating the container 10 to prevent the goods from slipping in relation to the goods receptacle.

After docking the container 10 ( 5a) become the container lid 20th and the port door 56 open together to reveal the port opening. For this purpose is the isolator 14th near the port opening with a single in the clean room 12th protruding glove engagement (not shown) provided, in which an operator inserts the hand to a release lever 61 the port door 56 to operate and to unlock it. After that, the port door will be 56 and the container lid 20th together around a vertical pivot axis arranged laterally next to the port opening to one side into the clean room 12th panned in, as in 5b shown.

In order to enable the goods to be picked up in the docked state 30th partially from the container 10 out and into the clean room 12th to move into the clean room without an operator wearing the glove 12th reach in and the Gutaufnahme 30th through the port opening from the container 10 must pull out is at the Gutaufnahme 30th a ferromagnetic and / or permanent magnetic body 62 attached, which is with the help of an outside and below the container 10 linear on the peripheral wall 22nd along moving magnets 64 contactless through the peripheral wall by means of magnetic forces of attraction 22nd through parallel to the linear guide 34 lets move to the tight with the body 62 connected asset intake 30th to move from the transport position into the removal position and back into the transport position after the goods have been removed.

As best in 4th , 5a and 5b depicted, the body is standing 62 down over the plate 46 the intake 30th over, being rigid with the plate 46 connected is. The body 62 has an extended lower part 66 which extends up to the immediate vicinity of the peripheral wall 22nd extends downwards. The one to the perimeter wall 22nd adjacent bottom of the body 62 is according to the curvature of the peripheral wall 22nd curved and through a thin air gap 68 with a constant gap width of 0.5 to 1 mm from the peripheral wall 22nd separately, as best in the 6th to 11 shown.

When the gut intake 30th in the transport position ( 5a) is, the body is 62 close to the front wall 24 . When the gut intake 30th in the removal position ( 5b) is, the body is 30th next to the opening 26th , but still inside the container 10 .

As best in 4th shown is the magnet 64 Part of a sled 70 along two round bars serving as linear guides 72 parallel to the horizontal top of the table 58 is movable. The ends of the round bars 72 are supported by two supports protruding from the top of the table 74 kept their height at the height of the legs 28 of the container 10 is adapted. This ensures that the magnet 64 below the perimeter wall 22nd along the round bars 72 is displaceable, its to the peripheral wall 22nd adjacent top according to the curvature of the peripheral wall 22nd curved and through a thin air gap 76 with a constant gap width of 0.5 to 1 mm from the peripheral wall 22nd is separated after the container 10 parked on the table top and a vertical longitudinal center plane of the container 10 in the middle between the round bars 72 and has been aligned parallel to them. For moving the slide 70 along the two round bars 72 a handle protruding to one side is used 78 .

In the embodiments in the 6th to 10 is the body 62 a single ferromagnetic body 62 made of soft iron that is in a wrapping 80 made of thin non-magnetic stainless steel sheet is enclosed.

In the embodiment in 6th is the magnet 64 a single cube-shaped neodymium (NdFeB) magnet 82 inserted into the plastic or Existing metal sled 70 embedded or inserted.

The second embodiment in 7th differs from the first embodiment in 6th by being in the carriage 70 a single cylindrical ferrite magnet 84 is embedded or inserted, its the peripheral wall 22nd facing surface in the plane of the 7th one to the radius of curvature of the peripheral wall 22nd corresponding radius of curvature to the magnet 84 closer to the peripheral wall 22nd move closer.

In the third embodiment in 8th are several disk-shaped neodymium (NdFeB) magnets 86 next to one another in the circumferential direction and in the direction of movement of the carriage 70 one after the other in the slide 70 embedded or inserted, with their end faces largely parallel to the opposite section of the peripheral wall 22nd are aligned. The neodymium magnets 86 are oriented so that they are opposite from the peripheral wall 22nd North Poles and South Poles both along the perimeter wall 22nd and alternate in the direction of movement.

In the fourth embodiment in 9 are several bar-shaped (NdFeB) magnets 88 with a ferromagnetic yoke with a U-shaped cross section 90 made of steel in the circumferential direction next to each other in the slide 70 embedded or inserted. The yoke 90 serves to keep the magnetic field lines on the from the peripheral wall 22nd facing away from the magnets 88 to that to the peripheral wall 22nd to deflect the adjacent side, creating the attractive forces between the magnets 88 and the body 62 grow.

In the fifth embodiment in 10 is as a magnet 64 an electromagnet 92 with an iron core 94 into a hole 96 of the sled 70 used. The iron core 94 has a curved end face with a radius of curvature of the peripheral wall 22nd adjusted radius of curvature.

In the sixth embodiment in 11 includes the permanent and ferromagnetic body 62 several cylindrical ones with a ferromagnetic pot 98 Neodymium (NdFeB) magnets 100 made of steel, which are next to one another in the circumferential direction and one behind the other in the direction of movement in the body 62 are inserted or embedded. In the sleigh 70 are corresponding neodymium magnets 102 inserted or embedded in a ferromagnetic pot 104 include steel. The magnets 100 and 102 are aligned so that the north poles of the magnets 102 in the sled 70 South Poles of the Magnets 100 in the body 62 opposite and vice versa.

Instead of the pot magnets 100 and 102 in the body 62 and in the sled 70 Cylindrical, disk-shaped or other shaped permanent magnets can also be provided there. Instead of a single body 62 several separate bodies (not shown) can also be attached to the crop receptacle 30th be attached, on each of which one or more external magnets (not shown) act.

In principle, the opposite orientation as in the exemplary embodiments of FIG 6th to 8th possible by adding a rigid to the Gutaufnahme 30th attached permanent magnetic body with one or more magnets by means of an outside of the container 10 arranged ferromagnets, for example by means of a ferromagnetic slide 70 , is moved.

After opening the port door 56 and the container lid 20th the operator moves the slide 70 by means of the handle 78 towards the boundary wall 52 of the isolator 14th . The effect between the magnet 64 and the body 62 contactless through the peripheral wall 22nd Magnetic forces of attraction acting through it through a magnetic coupling that the body 62 from the magnet 64 towards the isolator 14th is carried. This has the consequence that the Gutaufnahme 30th along the rails 42 towards the isolator 14th moves, with sufficiently large forces of attraction the rolling friction on the rails 42 overcomes. The crop intake moves 30th through the port opening into its removal position, in which it is a little way into the clean room 12th protrudes as in 5b shown. A movement of the crop 30th beyond this position is achieved by striking the slide 70 against that to the isolator 14th adjacent column 74 prevented.

After the material has been removed, the operator removes the slide 70 from the isolator 14th moves away until it hits the from the isolator 14th removed support 74 strikes and the Gutaufnahme 30th is back in its transport position.

QUOTES INCLUDED IN THE DESCRIPTION

This list of the documents listed by the applicant was generated automatically and is included solely for the better information of the reader. The list is not part of the German patent or utility model application. The DPMA assumes no liability for any errors or omissions.

Patent literature cited

• EP 2823828 A1 [0004]
• DE 102016001027 A1 [0009]
• WO 2017/129362 A1 [0009]

Claims (14)

Container (10) for transporting sterile goods and for removing the goods in a clean room (12) of an isolator (14), with an opening (26) and a container-side part (18) of a rapid transfer port system, one Container lid (20) for closing the opening (26) and means (46) for docking the container (10) on a complementary isolator-side part (16) of the rapid transfer port system, as well as with one in relation to the container (10 ) Movable material receptacle (30), which in a transport position is located entirely within the closed container (10) and, when the container (10) is docked and the container lid (20) is open, can be moved along a linear guide (34) into a removal position in which it is at least partially protrudes through the opening (26) into the clean room (12), characterized by at least one ferromagnetic and / or permanent magnetic body (62) mounted on the material receptacle (30), which is located in the vicinity of a peripheral wall (22) of the container (10) at orderly and by means of at least one magnet (64) or ferromagnet parallel to the linear guide (34) which acts on the body (62) in a contactless manner on the body (62) and moves linearly along the circumferential wall (22) outside the container (10) and with magnetic forces of attraction through the circumferential wall (22) ) can be moved in order to move the crop receptacle (30) into the removal position and back into the transport position without engaging in the isolator (14). Container (10) Claim 1 characterized by two opposite ends and a generally uniform container cross-section between the ends, the opening (26) being located at one end and the body (62) being located near the other end when the crop receptacle (30) is in is in the transport position. Container (10) Claim 1 or 2 , characterized in that the peripheral wall (22) consists of a non-magnetic austenitic stainless steel. Container (10) according to one of the preceding claims, characterized in that the at least one body (62) and / or the at least one magnet (64) is at a distance from the peripheral wall (22), so that between the peripheral wall (22) and an opposite surface of the body (62) and / or magnet (64) an air gap (68, 76) is present. Container (10) according to one of the preceding claims, characterized in that the peripheral wall (22) is cylindrical and that the at least one body (62) and / or the at least one magnet (64) has a surface opposite the peripheral wall (22) with a Has circular arc-shaped cross-section. Container (10) according to one of the preceding claims, characterized in that the at least one body (62) is provided with a casing (80) or coating made of a non-rusting material. Container (10) according to one of the Claims 1 to 6th , characterized in that the at least one body (62) consists of iron or steel. Container (10) according to one of the Claims 1 to 6th , characterized in that the at least one body (62) and / or the at least one magnet (64) consist partially or completely of a permanent magnetic rare earth or ferrite material. Container (10) Claim 8 , characterized in that the permanent magnetic rare earth material of the body (62) comprises at least one neodymium (NdFeB) magnet labeled SH, UH or EH. Container (10) according to one of the preceding claims, characterized in that the at least one ferromagnetic and / or permanent magnetic body (62) and / or the at least one magnet (64) has at least one pot magnet (100, 102) or permanent magnet (88) with a ferromagnetic pot (98, 104) or yoke (90) to deflect magnetic field lines on the side of the body (62) facing away from the peripheral wall (22) or magnets (64) to the side adjacent to the peripheral wall (22). Container (10) according to one of the preceding claims, characterized in that the at least one body (62) is arranged below the material receptacle (30). Combination of an isolator (14) with a clean room (12), an isolator-side part (18) of a rapid transfer port system and a container (10) docked thereon according to one of the preceding claims, characterized by at least one outside of the container ( 10) linearly on the circumferential wall (22) of the container (10) along movable magnets (64) or ferromagnets, which during its linear movement with magnetic forces of attraction through the circumferential wall (22) contactlessly on the at least one ferromagnetic and / or permanent magnetic body (62 ) acts to carry the body (62) parallel to the linear guide (34) and to move the crop receptacle (30) into the removal position and back into the transport position without engaging the isolator (14). Combination according to Claim 12 , characterized by a table (58) or carriage carrying the container (10) with a linear guide (72) for the at least one magnet (64) or ferromagnet. Method for transporting sterile goods in a container (10) which has an opening (26), a container-side part (18) of a rapid transfer port system with a container lid (20) for closing the opening (26) and an in Relation to the container (10) comprises movable goods receptacle (30), as well as for removing the goods in a clean room (12) of an isolator (14) which has a complementary isolator-side part (16) of the rapid transfer port system for docking the container (10), wherein the product receptacle (30) is in a transport position within the closed container (10) and, with the docked container (10) and the container lid (20) open, moves along a linear guide (34) into a removal position to remove the goods in which it protrudes at least partially through the opening (26) into the clean room (12), characterized in that the material receptacle (30) after the docking of the container (10) and the opening of the container lid (20) by means of at least one ferromagnetic and / or permanent magnetic body (62) mounted in the vicinity of a circumferential wall (22) of the container (10) on the crop receptacle (30) and moved linearly along the circumferential wall (22) by means of at least one outside of the container (10) and with Magnetic attraction forces through the peripheral wall (22) through contactless on the body (62) acting magnets (64) or ferromagnets without engagement in the insulator (14) is moved along the linear guide (34) into the removal position and back into the transport position.

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