[go: up one dir, main page]

DE102004019753A1 - Antiinflammatory finishing of hygiene articles, e.g. diapers or tampons, to prevent inflammation on contact with skin, using phytosterols, especially from avocado oil non-saponifiable components - Google Patents

Antiinflammatory finishing of hygiene articles, e.g. diapers or tampons, to prevent inflammation on contact with skin, using phytosterols, especially from avocado oil non-saponifiable components Download PDF

Info

Publication number
DE102004019753A1
DE102004019753A1 DE102004019753A DE102004019753A DE102004019753A1 DE 102004019753 A1 DE102004019753 A1 DE 102004019753A1 DE 102004019753 A DE102004019753 A DE 102004019753A DE 102004019753 A DE102004019753 A DE 102004019753A DE 102004019753 A1 DE102004019753 A1 DE 102004019753A1
Authority
DE
Germany
Prior art keywords
phytosterols
hygiene articles
diapers
antiinflammatory
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102004019753A
Other languages
German (de)
Inventor
Christine Dr. Wild
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cognis IP Management GmbH
Original Assignee
Cognis Deutschland GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cognis Deutschland GmbH and Co KG filed Critical Cognis Deutschland GmbH and Co KG
Priority to DE102004019753A priority Critical patent/DE102004019753A1/en
Publication of DE102004019753A1 publication Critical patent/DE102004019753A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
    • D06M13/00—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment
    • D06M13/005—Compositions containing perfumes; Compositions containing deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/432—Inhibitors, antagonists

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Textile Engineering (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Cosmetics (AREA)

Abstract

The use of phytosterols (I) is claimed for the production of antiinflammatory-finished hygiene articles. Independent claims are included for antiinflammatory-finished hygiene articles containing avocado phytosterols or the non-saponifiable components of avocado oil. ACTIVITY : Antiinflammatory; Dermatological. MECHANISM OF ACTION : Prostaglandin E-2 (PGE-2) release inhibitor. A formulation comprising (by weight) 1% Avocadol(RTM; avocado oil non-saponifiable components) (Ia) in a lotion consisting of 55% mixture of coconut partial and tri-glycerides, 15% glycerol monolaurate, 20% polyvinyl stearyl ether and 5 wt. % silicone wax was applied at 10 g/m 2>to conventional diapers, which were contacted with skin for 20 hours. The content of the inflammation mediator PGE-2 in the skin was 8000 pg, compared with 15000 pg using untreated diapers and 13000 pg using diapers treated with the lotion base without (Ia).

Description

Gebiet der ErfindungTerritory of invention

Die Erfindung befindet sich auf dem Gebiet der Hygieneartikel und betrifft die Verwendung von Phytosterolen zur Herstellung anti-inflammatorisch ausgerüsteter Hygieneartikel, sowie die entsprechenden Hygieneartikel enthaltend Phytosterole.The This invention is in the field of sanitary articles and concerns the use of phytosterols to produce anti-inflammatory equipped Hygiene products, and containing the corresponding hygiene articles Phytosterols.

Fetthaltige Formulierungen zur Ausrüstung von Vliesstoffen, insbesondere von Vliesstoffen, die in Hygieneprodukten eingesetzt werden können, sind vielfach bekannt, beispielsweise beschreiben die deutsche Patentanmeldung DE 10206617 , die Europäische Anmeldung EP 1371773 A1 und die Internationale Patentanmeldung WO 96/16682 fetthaltige Formulierungen, die auf Hygieneartikel wie beispielsweise Windeln aufgetragen werden und einen hautschützenden Effekt ausüben.Fatty formulations for finishing nonwovens, in particular nonwovens, which can be used in hygiene products, are widely known, for example, describe the German patent application DE 10206617 , the European application EP 1371773 A1 and International Patent Application WO 96/16682 describe greasy formulations applied to sanitary articles such as diapers and having a skin-protecting effect.

Dennoch scheinen auch diese Imprägnierungen noch keinen ausreichenden Schutz empfindlicher Hautpartien gegen Reizungen, Entzündungen oder Verletzungen zu gewährleisten. Es werden daher unzählige Wirkstoffe vorgeschlagen, die zum Erhalt einer gesunden intakten Hautoberfläche beitragen sollen. Jedoch hat sich bisher kein Wirkstoff durchgesetzt der gerade bei Hygieneartikeln, die sich durch einen längeren Kontakt mit empfindlicher und oft gereizter Hautbereiche auszeichnen, Entzündungen ausreichend vorbeugt.Yet also these impregnations seem still not sufficient protection of sensitive skin against Irritation, inflammation or injury. It will therefore countless Active ingredients suggested to maintain a healthy intact skin surface should contribute. However, no drug has prevailed so far the straight with hygiene articles, which are characterized by a longer contact characterized by sensitive and often irritated areas of the skin, inflammation sufficiently prevents.

Die Aufgabe der vorliegenden Erfindung hat daher darin bestanden, Hygieneartikel zur Verfügung zu stellen, die sich durch eine verbesserte anti-inflammatorische Wirkung auszeichnen.The Object of the present invention has therefore consisted, hygiene articles to disposal to face, characterized by an improved anti-inflammatory Distinguish effect.

Beschreibung der Erfindungdescription the invention

Gegenstand der Erfindung ist die Verwendung von Phytosterolen zur Herstellung von anti-inflammatorisch ausgerüsteten Hygieneartikeln.object The invention relates to the use of phytosterols for the production of anti-inflammatory equipped Hygiene articles.

Typische Beispiele für geeignete Phytosterole sind beispielsweise Ergosterole, Campesterole, Stigmasterole, Brassicasterole sowie vorzugsweise Sitosterole bzw. Sitostanole insbesondere β-Sitosterol, sowie deren Derivate und insbesondere Ester.typical examples for suitable phytosterols are, for example, ergosterols, campesterols, Stigmasterole, Brassicasterole and preferably sitosterols or Sitostanols, in particular β-sitosterol, and their derivatives and in particular esters.

Es wurde überraschender Weise festgestellt, dass Phytosterole insbesondere Phytosterole aus der Avocado eine ausgezeichnete anti-inflammatorische Wirkung aufweisen, wenn sie aufgetragen oder eingearbeitet in Hygieneartikeln in Kontakt mit gereizter oder entzündeter Haut kommen.It became more surprising Way stated that phytosterols in particular phytosterols from the avocado an excellent anti-inflammatory effect exhibit when applied or incorporated in hygiene articles come into contact with irritated or inflamed skin.

Die Avocado (Persea americana MILL., Synonym. Persea gratissima GAERTN.f.) ist eine tropische Beerenfrucht, die zur Familie der Lauraceae zählt. Die sogenannte Avocadobirne weist einen sehr hohen Fettgehalt von bis zu 30 Gew.% auf. Die Avocadobirnen werden kaltgepreßt und die schleimigen Beimengungen durch Zentrifugieren und Filtern entfernt. Dieses "rohe" Öl ist grün, trüb und enthält einen natürlich hohen Anteil an Unverseifbarem (über 1 %). Der Hauptbestandteil des unverseifbaren Anteils des Avocadoöls sind Phytosterole. Der unverseifbare Anteil ist im Handel unter dem Namen Avocadol® von der Firma Cosmo Care erhältlich.The avocado (Persea americana MILL., Synonym Persea gratissima GAERTN.f.) Is a tropical berry fruit that belongs to the family of Lauraceae. The so-called avocado pear has a very high fat content of up to 30% by weight. The avocado pears are cold pressed and the slimy admixtures are removed by centrifuging and filtering. This "raw" oil is green, cloudy and contains a naturally high proportion of unsaponifiable (above 1%). The main constituent of the unsaponifiable portion of avocado oil is phytosterols. The unsaponifiable component is commercially available under the name Avocadol ® by Cosmo Care.

Die Phytosterole oder der unverseifbare Anteil des Avocadoöls lassen sich besonders gut in fetthaltige Formulierungen, Lotionen oder Emulsionen einarbeiten, um dann auf die Hygieneartikel aufgetragen zu werden.The Leave phytosterols or the unsaponifiable portion of avocado oil Especially good in fatty formulations, lotions or Incorporate emulsions, then applied to the toiletries to become.

Besonders bewährt haben sich dabei Formulierungen der in der deutschen Patentanmeldung DE 10206617 offenbarten Zusammensetzungen enthaltend a) 5 bis 50 Gew.-% einer im Bereich von 25 bis 37°C schmelzende Komponente, ausgewählt aus der Gruppe der Paraffine, Fettsäureester, Polyhydroxyfettsäureester, Fettalkohole, alkoxylierten Fettsäureester, alkoxylierten Fettalkohole und Mischungen dieser Verbindungen und b) 5 bis 50 Gew.-% einer im Bereich von 40 bis 60°C schmelzende Komponente, ausgewählt aus der Gruppe der Polyhydroxyfettsäureester, C14-C22-Fettalkohole, C12-C22-Fettsäuren, den alkoxylierten Derivaten der Fettalkohole und -ester, sowie Mischungen dieser Komponenten, und c) 5 bis 25 Gew.-% Wasser, sowie Formulierungen, die in der europäischen Patentanmeldung EP 1371773 A1 beschrieben werden mit weniger als 5 Gew. % Wasser, enthaltend a) 5 bis 70 Gew.-% einer im Bereich von 25 bis 37°C schmelzenden Komponente, ausgewählt aus der Gruppe der synthetischen Wachse, Paraffine, Fettsäureester, Polyhydroxyfettsäureester, Fettalkohole, alkoxylierten Fettsäureester, alkoxylierten Fettalkohole und Mischungen dieser Ver bindungen und b) 5 bis 70 Gew.-% einer Komponente mit einem Schmelzpunkt, der mindestens 5 °C höher als der der Komponente a) ist, ausgewählt aus der Gruppe der Paraffine, Polyhydroxyfettsäureester, C14-C22-Fettalkohole, C12-C22-Fettsäuren, den alkoxylierten Derivaten der Fettalkohole und -ester, sowie Mischungen dieser Komponenten, und c) 5 bis 25 Gew.-% eines Kristallisationsbeschleunigers mit einem Schmelzpunkt von 45 bis 70 ° C ausgewählt aus der Gruppe, die gebildet wird von Partialglyceriden, Ethylenglycoldiestern und polymeren Wachsen.In this case, formulations of the type described in the German patent application have proven particularly useful DE 10206617 disclosed compositions comprising a) from 5 to 50% by weight of a component melting in the range from 25 to 37 ° C selected from the group of paraffins, fatty acid esters, polyhydroxy fatty acid esters, fatty alcohols, alkoxylated fatty acid esters, alkoxylated fatty alcohols and mixtures of these compounds and b) 5 to 50 wt .-% of a melting in the range of 40 to 60 ° C component selected from the group of polyhydroxy fatty acid esters, C14-C22 fatty alcohols, C12-C22 fatty acids, the alkoxylated derivatives of fatty alcohols and esters, and mixtures of these components , and c) 5 to 25% by weight of water, as well as formulations described in the European patent application EP 1371773 A1 be described with we less than 5% by weight of water containing a) from 5 to 70% by weight of a component melting in the range from 25 to 37 ° C selected from the group of synthetic waxes, paraffins, fatty acid esters, polyhydroxy fatty acid esters, fatty alcohols, alkoxylated fatty acid esters, alkoxylated Fatty alcohols and mixtures of these compounds Ver and b) 5 to 70 wt .-% of a component having a melting point which is at least 5 ° C higher than that of component a) selected from the group of paraffins, polyhydroxy fatty acid esters, C14-C22 fatty alcohols , C12-C22 fatty acids, the alkoxylated derivatives of fatty alcohols and esters, and mixtures of these components, and c) 5 to 25% by weight of a crystallization accelerator having a melting point of 45 to 70 ° C selected from the group that is formed of partial glycerides, ethylene glycol diesters and polymeric waxes.

Ein weiterer Gegenstand der Erfindung sind somit anti-inflammatorisch ausgerüstete Hygieneartikel enthaltend Phytosterole der Avocado und anti-inflammatorisch ausgerüstete Hygieneartikel enthaltend unverseifbare Anteile des Avocadoöls.One Another object of the invention are thus anti-inflammatory equipped Sanitary products containing avocado phytosterols and anti-inflammatory equipped Hygiene articles containing unsaponifiable portions of avocado oil.

Unter dem Begriff Hygieneartikel sind beispielsweise Windeln, Slipeinlagen, Inkontinenzartikel, Damenbinden, Tampons oder Kosmetiktücher zu verstehen. Die entsprechenden Hygieneartikel enthalten je nach Anwendungsbereich 0,1 bis 500 g, vorzugsweise 0,5 bis 100 g und besonders bevorzugt 1 bis 30 g der phytosterolhaltigen Formulierung pro m2 Fläche.By way of example, hygiene articles are to be understood as meaning diapers, panty liners, incontinence articles, sanitary napkins, tampons or facial tissues. Depending on the field of application, the corresponding hygiene articles contain 0.1 to 500 g, preferably 0.5 to 100 g and more preferably 1 to 30 g of the phytosterol-containing formulation per m 2 surface.

Die unverseifbaren Anteile des Avocadoöls werden beispielsweise in Mengen von 0,01 bis 10 Gew.%, vorzugsweise 0,1 bis 5 Gew. %, besonders bevorzugt 0,3 bis 2 Gew.% in die fetthaltige Formulierung eingearbeitet.The unsaponifiable portions of the avocado oil are for example in Amounts of 0.01 to 10% by weight, preferably 0.1 to 5% by weight, especially preferably 0.3 to 2 wt.% incorporated in the fatty formulation.

Anti-inflammatorische WirkungAnti-inflammatory effect

Unterschiedliche entzündungshemmende Formulierungen wurden am PGE-2 (Prostaglandin E2) Freisetzungs-Haut-Modell getestet. PGE-2 ist ein Entzündungsmediator, dessen Freisetzung bei entzündungshemmender Wirkung unterdrückt wird.different anti-inflammatory Formulations were made on the PGE-2 (prostaglandin E2) release skin model tested. PGE-2 is an inflammatory mediator, its release in anti-inflammatory Effect suppressed becomes.

Die entsprechenden Wirkstoffe wurden durch gemeinsames Aufschmelzen und Mischen in eine Formulierung gemäß der Europäischen Patentanmeldung EP 1371773 A1 mit der Zusammensetzung:

  • a) 55 Gew. % einer Mischung aus Partialglyceriden und Triglyceriden von Cocosfettsäuren, Schmp.: 34°C
  • b) 15 Gew. % Glycerolmonolaurate, Schmp. 63°C
  • c) 20 Gew. Polyvinylstearylether, Schmp. 45°C
  • d) 5 Gew. % Siliconwachs
eingearbeitet. Diese Formulierung wurde dann auf handelsübliche Windeln in einer Menge von 10 g/m2 aufgetragen, die über 20 Stunden auf der entsprechenden Haut belassen wurden und der Gehalt an PGE-2 (pg) nach 20 stündiger Exposition bestimmt:
Figure 00040001
The corresponding active ingredients were prepared by co-melting and mixing in a formulation according to the European patent application EP 1371773 A1 with the composition:
  • a) 55% by weight of a mixture of partial glycerides and triglycerides of coconut fatty acids, mp .: 34 ° C.
  • b) 15% by weight of glycerol monolaurate, mp 63 ° C.
  • c) 20% by weight polyvinyl stearyl ether, mp 45 ° C.
  • d) 5% by weight of silicone wax
incorporated. This formulation was then applied to commercial diapers in an amount of 10 g / m 2 left on the skin for 20 hours and the PGE-2 (pg) content determined after 20 hours of exposure:
Figure 00040001

Claims (6)

Verwendung von Phytosterolen zur Herstellung von anti-inflammatorisch ausgerüsteten Hygieneartikeln.Use of phytosterols for the production of anti-inflammatory endowed Hygiene articles. Verwendung gemäß Anspruch 1, dadurch gekennzeichnet, dass die Phytosterole aus Avocado (Persea americana MILL) stammen.Use according to claim 1, characterized in that the phytosterols from avocado (Persea americana MILL). Verwendung gemäß den Ansprüchen 1 und 2, dadurch gekennzeichnet, dass die Phytosterole aus den unverseifbaren Anteilen des Avocadoöls stammen.Use according to claims 1 and 2, characterized in that the phytosterols from the unsaponifiable Proportions of avocado oil come. Verwendung gemäß den Ansprüchen 1 bis 3, dadurch gekennzeichnet, dass die Phytosterole in einer fetthaltigen Formulierung, Emulsion oder Lotion zur Herstellung von anti-inflammatorisch ausgerüsteteten Hygieneartikeln eingesetzt werden.Use according to claims 1 to 3, characterized in that the phytosterols in a fatty Formulation, emulsion or lotion for the production of anti-inflammatory-equipped Hygiene articles are used. Anti-inflammatorisch ausgerüstete Hygieneartikel enthaltend Phytosterole der Avocado.Containing anti-inflammatory hygiene articles Phytosterols of the avocado. Anti-inflammatorisch ausgerüstete Hygieneartikel enthaltend unverseifbare Anteile des Avocadoöls.Containing anti-inflammatory hygiene articles unsaponifiable portions of avocado oil.
DE102004019753A 2004-04-23 2004-04-23 Antiinflammatory finishing of hygiene articles, e.g. diapers or tampons, to prevent inflammation on contact with skin, using phytosterols, especially from avocado oil non-saponifiable components Withdrawn DE102004019753A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE102004019753A DE102004019753A1 (en) 2004-04-23 2004-04-23 Antiinflammatory finishing of hygiene articles, e.g. diapers or tampons, to prevent inflammation on contact with skin, using phytosterols, especially from avocado oil non-saponifiable components

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004019753A DE102004019753A1 (en) 2004-04-23 2004-04-23 Antiinflammatory finishing of hygiene articles, e.g. diapers or tampons, to prevent inflammation on contact with skin, using phytosterols, especially from avocado oil non-saponifiable components

Publications (1)

Publication Number Publication Date
DE102004019753A1 true DE102004019753A1 (en) 2005-11-24

Family

ID=35219803

Family Applications (1)

Application Number Title Priority Date Filing Date
DE102004019753A Withdrawn DE102004019753A1 (en) 2004-04-23 2004-04-23 Antiinflammatory finishing of hygiene articles, e.g. diapers or tampons, to prevent inflammation on contact with skin, using phytosterols, especially from avocado oil non-saponifiable components

Country Status (1)

Country Link
DE (1) DE102004019753A1 (en)

Similar Documents

Publication Publication Date Title
DE69213930T2 (en) FAT PREPARATIONS AND THEIR USE IN EMULSION PRODUCTS LIKE COSMETICS AND PHARMACEUTICALS
DE2719533A1 (en) AGENT FOR TONING THE SKIN ON THE BASIS OF PYRIDINE DERIVATIVES
DE69405649T2 (en) Sunscreen containing compositions
DE2241016B2 (en) Emulsifier combination for creams from T ^ p water in oil and their use
WO1992022282A1 (en) Oil components for cosmetic and pharmaceutical preparations
DE3215912A1 (en) WOOL WAX REPLACEMENT PRODUCT
DE3633453A1 (en) COMPOSITIONS BASED ON LYSINE AND ARGININE SALTS
DE102007006778A1 (en) New shower oil
EP2525769B1 (en) Adhesive cream
WO2024017699A2 (en) Method for producing a cosmetic water-in-oil emulsion from a glycerin-in-oil emulsion
EP0867176A2 (en) Shower preparations with a high oil content
CH641038A5 (en) EMOLLIENCES FOR COSMETIC EMULSIONS, CREAMS, PASTE AND PENCILS.
WO2021239360A1 (en) Peg-free soap gel preparation
DE102004019753A1 (en) Antiinflammatory finishing of hygiene articles, e.g. diapers or tampons, to prevent inflammation on contact with skin, using phytosterols, especially from avocado oil non-saponifiable components
WO1993002660A1 (en) Emulsifier concentrates
DE102017212913A1 (en) Skin care composition
EP1593370A1 (en) Glycerin ether mixture, a composition comprising glycerin ether mixture and a process for making the same
DE19852508C2 (en) Use of the unsaponified components from avocado
DE3418887A1 (en) COSMETIC OIL COMPONENT
DE19938327A1 (en) Cold processable wax dispersion
EP1503729B1 (en) Composition and the use thereof as a pharmaceutical or cosmetic formulation for external use
DE3137017C2 (en) Soap bar with a deodorizing effect
DE3234786A1 (en) EMULSIFIER COMBINATIONS FOR EMULSIONS OF THE WATER-IN-OIL TYPE AND THEIR USE
EP1534234B1 (en) Composition and use thereof as a pharmaceutical or cosmetic formulation for external application
DE102008045523A1 (en) Composition, useful for treating wound after periodontal treatment and preparing wound dressing, comprises wax ester comprising jojoba oil, metal hydroxide comprising calcium hydroxide, and optionally radiopaque filler

Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: COGNIS IP MANAGEMENT GMBH, 40589 DUESSELDORF, DE

R012 Request for examination validly filed

Effective date: 20110419

R119 Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee
R119 Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee

Effective date: 20131101