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DD297960A5 - Indenoindolverbindungen ii - Google Patents

Indenoindolverbindungen ii Download PDF

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Publication number
DD297960A5
DD297960A5 DD90341939A DD34193990A DD297960A5 DD 297960 A5 DD297960 A5 DD 297960A5 DD 90341939 A DD90341939 A DD 90341939A DD 34193990 A DD34193990 A DD 34193990A DD 297960 A5 DD297960 A5 DD 297960A5
Authority
DD
German Democratic Republic
Prior art keywords
tetrahydro
indole
cis
formula
thii
Prior art date
Application number
DD90341939A
Other languages
German (de)
English (en)
Inventor
Malcolm Sainsbury
Howard G Shartzer
Original Assignee
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��@���������@�������k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ���@����������@��k��, ��@���������@�������k�� filed Critical ���@����������@��k��
Publication of DD297960A5 publication Critical patent/DD297960A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/94[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DD90341939A 1989-06-22 1990-06-21 Indenoindolverbindungen ii DD297960A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8902274A SE8902274D0 (sv) 1989-06-22 1989-06-22 Indenoidole compounds ii

Publications (1)

Publication Number Publication Date
DD297960A5 true DD297960A5 (de) 1992-01-30

Family

ID=20376370

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90341939A DD297960A5 (de) 1989-06-22 1990-06-21 Indenoindolverbindungen ii

Country Status (34)

Country Link
EP (1) EP0409410B1 (no)
JP (1) JP3064411B2 (no)
KR (1) KR920702679A (no)
CN (1) CN1033029C (no)
AT (1) ATE135688T1 (no)
BG (1) BG60317B2 (no)
CA (1) CA2060897A1 (no)
DD (1) DD297960A5 (no)
DE (1) DE69025998T2 (no)
DK (1) DK0409410T3 (no)
DZ (1) DZ1428A1 (no)
ES (1) ES2084660T3 (no)
FI (1) FI100800B (no)
GR (1) GR3019779T3 (no)
HR (1) HRP920903B1 (no)
HU (1) HUT59097A (no)
IE (1) IE74682B1 (no)
IL (1) IL94830A (no)
IS (1) IS3590A7 (no)
LT (1) LT3675B (no)
LV (1) LV10253B (no)
MX (1) MX21244A (no)
MY (1) MY107311A (no)
NO (1) NO177932C (no)
NZ (1) NZ234175A (no)
PL (1) PL167761B1 (no)
PT (1) PT94468B (no)
RO (1) RO111573B1 (no)
RU (1) RU2104270C1 (no)
SE (1) SE8902274D0 (no)
SI (1) SI9011223B (no)
WO (1) WO1990015799A1 (no)
YU (1) YU122390A (no)
ZA (1) ZA904827B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO1676B1 (en) * 1990-10-16 1992-08-09 جامعة باث Extra compounds indinol II
JPH0656669A (ja) * 1992-06-11 1994-03-01 Asahi Breweries Ltd 活性酸素消去作用を持つプテリン誘導体製剤
SE9302431D0 (sv) * 1993-07-16 1993-07-16 Ab Astra Use of indenoindole compounds
CA2128283A1 (fr) * 1993-07-20 1995-01-21 Paul Caubere (thia)cycloalkyl¬b|indoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6288099B1 (en) 1998-12-04 2001-09-11 American Home Products Corporation Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
CN1333774A (zh) * 1998-12-04 2002-01-30 美国家庭用品有限公司 以取代苯并呋喃并吲哚和茚并[1,2-b]吲哚作为新的钾通道开放剂
FR2826009B1 (fr) * 2001-06-13 2003-08-15 Servier Lab Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
RU2008105071A (ru) 2005-07-14 2009-08-20 Айрм Ллк (Bm) Соединения и композиции в качестве миметиков tro
DE102006047231B4 (de) * 2006-10-04 2009-02-12 Hemmerling, Hans-Jörg, Dr. Substituierte Indeno[1,2-b]indolderivate als neue Hemmstoffe der Protein Kinase CK2 und ihre Verwendung als Tumor Therapeutika, Cytostatika und Diagnostika
EA026149B1 (ru) * 2011-06-16 2017-03-31 Корея Рисерч Инститьют Оф Кемикал Текнолоджи Производное инданона, его фармацевтически приемлемая соль или оптический изомер, способ его получения и содержащая его фармацевтическая композиция для профилактики или лечения вирусного заболевания
JP6293168B2 (ja) 2012-12-14 2018-03-14 コーリア リサーチ インスティテュート オブ ケミカル テクノロジー 新規の化合物、その薬学的に許容可能な塩又は光学異性体、それを作製する方法、及びそれを有効成分として含有するウイルス疾患の予防又は治療用の医薬組成物
JP2023520819A (ja) 2020-04-20 2023-05-19 ノバルティス アーゲー 抗ウイルス1,3-ジ-オキソ-インデン化合物

Also Published As

Publication number Publication date
IE902247A1 (en) 1991-01-16
NZ234175A (en) 1992-12-23
LV10253A (lv) 1994-10-20
DE69025998T2 (de) 1996-08-08
PL285752A1 (en) 1991-03-11
KR920702679A (ko) 1992-10-06
HRP920903B1 (en) 1998-06-30
DE69025998D1 (de) 1996-04-25
EP0409410A1 (en) 1991-01-23
SI9011223A (en) 1997-10-31
ES2084660T3 (es) 1996-05-16
CN1033029C (zh) 1996-10-16
IE902247L (en) 1990-12-22
FI915999A0 (fi) 1991-12-19
WO1990015799A1 (en) 1990-12-27
RU2104270C1 (ru) 1998-02-10
IL94830A0 (en) 1991-04-15
NO915049D0 (no) 1991-12-20
AU644084B2 (en) 1993-12-02
YU122390A (sh) 1992-09-07
CA2060897A1 (en) 1990-12-23
DZ1428A1 (fr) 2004-09-13
IL94830A (en) 1996-07-23
JPH04505923A (ja) 1992-10-15
PL167761B1 (pl) 1995-10-31
HUT59097A (en) 1992-04-28
BG60317B2 (bg) 1994-07-25
NO177932B (no) 1995-09-11
MX21244A (es) 1994-03-31
RO111573B1 (ro) 1996-11-29
EP0409410B1 (en) 1996-03-20
IS3590A7 (is) 1990-12-23
HU904825D0 (en) 1992-03-30
ATE135688T1 (de) 1996-04-15
JP3064411B2 (ja) 2000-07-12
HRP920903A2 (hr) 1994-04-30
LT3675B (en) 1996-01-25
AU5836990A (en) 1991-01-08
NO177932C (no) 1995-12-20
FI100800B (fi) 1998-02-27
LTIP912A (en) 1995-03-27
DK0409410T3 (da) 1996-04-29
PT94468B (pt) 1997-12-31
SI9011223B (sl) 1998-08-31
NO915049L (no) 1992-02-21
PT94468A (pt) 1991-02-08
SE8902274D0 (sv) 1989-06-22
CN1051554A (zh) 1991-05-22
GR3019779T3 (en) 1996-07-31
IE74682B1 (en) 1997-07-30
ZA904827B (en) 1991-04-24
MY107311A (en) 1995-11-30
LV10253B (en) 1995-04-20

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