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DD297960A5 - Indenoindolverbindungen ii - Google Patents

Indenoindolverbindungen ii Download PDF

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Publication number
DD297960A5
DD297960A5 DD90341939A DD34193990A DD297960A5 DD 297960 A5 DD297960 A5 DD 297960A5 DD 90341939 A DD90341939 A DD 90341939A DD 34193990 A DD34193990 A DD 34193990A DD 297960 A5 DD297960 A5 DD 297960A5
Authority
DD
German Democratic Republic
Prior art keywords
tetrahydro
indole
cis
formula
thii
Prior art date
Application number
DD90341939A
Other languages
German (de)
English (en)
Inventor
Malcolm Sainsbury
Howard G Shartzer
Original Assignee
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��@���������@�������k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ���@����������@��k��, ��@���������@�������k�� filed Critical ���@����������@��k��
Publication of DD297960A5 publication Critical patent/DD297960A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/94[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DD90341939A 1989-06-22 1990-06-21 Indenoindolverbindungen ii DD297960A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8902274A SE8902274D0 (sv) 1989-06-22 1989-06-22 Indenoidole compounds ii

Publications (1)

Publication Number Publication Date
DD297960A5 true DD297960A5 (de) 1992-01-30

Family

ID=20376370

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90341939A DD297960A5 (de) 1989-06-22 1990-06-21 Indenoindolverbindungen ii

Country Status (34)

Country Link
EP (1) EP0409410B1 (fi)
JP (1) JP3064411B2 (fi)
KR (1) KR920702679A (fi)
CN (1) CN1033029C (fi)
AT (1) ATE135688T1 (fi)
BG (1) BG60317B2 (fi)
CA (1) CA2060897A1 (fi)
DD (1) DD297960A5 (fi)
DE (1) DE69025998T2 (fi)
DK (1) DK0409410T3 (fi)
DZ (1) DZ1428A1 (fi)
ES (1) ES2084660T3 (fi)
FI (1) FI100800B (fi)
GR (1) GR3019779T3 (fi)
HR (1) HRP920903B1 (fi)
HU (1) HUT59097A (fi)
IE (1) IE74682B1 (fi)
IL (1) IL94830A (fi)
IS (1) IS3590A7 (fi)
LT (1) LT3675B (fi)
LV (1) LV10253B (fi)
MX (1) MX21244A (fi)
MY (1) MY107311A (fi)
NO (1) NO177932C (fi)
NZ (1) NZ234175A (fi)
PL (1) PL167761B1 (fi)
PT (1) PT94468B (fi)
RO (1) RO111573B1 (fi)
RU (1) RU2104270C1 (fi)
SE (1) SE8902274D0 (fi)
SI (1) SI9011223B (fi)
WO (1) WO1990015799A1 (fi)
YU (1) YU122390A (fi)
ZA (1) ZA904827B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT99232A (pt) * 1990-10-16 1992-09-30 Univ Bath Processo de preparacao de compostos de indeno-indolo de composicoes farmaceuticas, e de estabilizacao de compostos susceptiveis de deterioracao oxidadtiva
JPH0656669A (ja) * 1992-06-11 1994-03-01 Asahi Breweries Ltd 活性酸素消去作用を持つプテリン誘導体製剤
SE9302431D0 (sv) * 1993-07-16 1993-07-16 Ab Astra Use of indenoindole compounds
CA2128283A1 (fr) * 1993-07-20 1995-01-21 Paul Caubere (thia)cycloalkyl¬b|indoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2000034285A2 (en) * 1998-12-04 2000-06-15 American Home Products Corporation Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
US6288099B1 (en) 1998-12-04 2001-09-11 American Home Products Corporation Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
FR2826009B1 (fr) * 2001-06-13 2003-08-15 Servier Lab Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US8153671B2 (en) 2005-07-14 2012-04-10 Irm Llc Heterotetracyclic compounds as TPO mimetics
DE102006047231B4 (de) * 2006-10-04 2009-02-12 Hemmerling, Hans-Jörg, Dr. Substituierte Indeno[1,2-b]indolderivate als neue Hemmstoffe der Protein Kinase CK2 und ihre Verwendung als Tumor Therapeutika, Cytostatika und Diagnostika
EP3597184A3 (en) * 2011-06-16 2020-04-22 Korea Research Institute of Chemical Technology Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases
ES2863985T3 (es) 2012-12-14 2021-10-13 Korea Res Inst Chemical Tech Nuevo compuesto, sal farmacéuticamente aceptable o isómero óptico del mismo, método para prepararlo y composición farmacéutica para la prevención o el tratamiento de enfermedades virales que lo contienen como ingrediente activo
CN115916763A (zh) 2020-04-20 2023-04-04 诺华股份有限公司 抗病毒素1,3-二氧代茚化合物

Also Published As

Publication number Publication date
CA2060897A1 (en) 1990-12-23
ATE135688T1 (de) 1996-04-15
HRP920903A2 (hr) 1994-04-30
DZ1428A1 (fr) 2004-09-13
SI9011223B (sl) 1998-08-31
NO915049L (no) 1992-02-21
AU644084B2 (en) 1993-12-02
MX21244A (es) 1994-03-31
JPH04505923A (ja) 1992-10-15
IE74682B1 (en) 1997-07-30
ES2084660T3 (es) 1996-05-16
EP0409410B1 (en) 1996-03-20
BG60317B2 (bg) 1994-07-25
AU5836990A (en) 1991-01-08
HRP920903B1 (en) 1998-06-30
PL167761B1 (pl) 1995-10-31
NZ234175A (en) 1992-12-23
NO177932B (no) 1995-09-11
GR3019779T3 (en) 1996-07-31
LV10253A (lv) 1994-10-20
FI100800B (fi) 1998-02-27
PT94468A (pt) 1991-02-08
NO915049D0 (no) 1991-12-20
RU2104270C1 (ru) 1998-02-10
HUT59097A (en) 1992-04-28
HU904825D0 (en) 1992-03-30
LT3675B (en) 1996-01-25
PL285752A1 (en) 1991-03-11
JP3064411B2 (ja) 2000-07-12
WO1990015799A1 (en) 1990-12-27
FI915999A0 (fi) 1991-12-19
IE902247A1 (en) 1991-01-16
IS3590A7 (is) 1990-12-23
IL94830A0 (en) 1991-04-15
MY107311A (en) 1995-11-30
ZA904827B (en) 1991-04-24
SE8902274D0 (sv) 1989-06-22
DE69025998D1 (de) 1996-04-25
DE69025998T2 (de) 1996-08-08
YU122390A (sh) 1992-09-07
SI9011223A (en) 1997-10-31
CN1033029C (zh) 1996-10-16
PT94468B (pt) 1997-12-31
NO177932C (no) 1995-12-20
CN1051554A (zh) 1991-05-22
RO111573B1 (ro) 1996-11-29
LTIP912A (en) 1995-03-27
IE902247L (en) 1990-12-22
DK0409410T3 (da) 1996-04-29
LV10253B (en) 1995-04-20
IL94830A (en) 1996-07-23
EP0409410A1 (en) 1991-01-23
KR920702679A (ko) 1992-10-06

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