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DD239202A5 - Verfahren zur herstellung von 9-chlor-1,5-benzothiazepin-derivaten - Google Patents

Verfahren zur herstellung von 9-chlor-1,5-benzothiazepin-derivaten Download PDF

Info

Publication number
DD239202A5
DD239202A5 DD85282915A DD28291585A DD239202A5 DD 239202 A5 DD239202 A5 DD 239202A5 DD 85282915 A DD85282915 A DD 85282915A DD 28291585 A DD28291585 A DD 28291585A DD 239202 A5 DD239202 A5 DD 239202A5
Authority
DD
German Democratic Republic
Prior art keywords
compound
chloro
methoxyphenyl
cis
general formula
Prior art date
Application number
DD85282915A
Other languages
German (de)
English (en)
Inventor
Mikio Takeda
Tokuro Oh-Ishi
Hiromichi Nakajima
Taku Nagao
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@�������@��K@���Kk�� filed Critical ������@�������@��K@���Kk��
Publication of DD239202A5 publication Critical patent/DD239202A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DD85282915A 1984-11-17 1985-11-15 Verfahren zur herstellung von 9-chlor-1,5-benzothiazepin-derivaten DD239202A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB08429102A GB2167063A (en) 1984-11-17 1984-11-17 6 or 9-chloro-1, 5-benzothiazepine derivatives
CN85101892A CN85101892B (zh) 1984-11-17 1985-04-01 制备新型的1，5-苯并硫杂吖庚因衍生物的方法

Publications (1)

Publication Number Publication Date
DD239202A5 true DD239202A5 (de) 1986-09-17

Family

ID=25741514

Family Applications (2)

Application Number Title Priority Date Filing Date
DD85282915A DD239202A5 (de) 1984-11-17 1985-11-15 Verfahren zur herstellung von 9-chlor-1,5-benzothiazepin-derivaten
DD85294053A DD249271A5 (de) 1984-11-17 1985-11-15 Verfahren zur herstellung von 9-chlor-1,5-benzothiazepin-derivaten

Family Applications After (1)

Application Number Title Priority Date Filing Date
DD85294053A DD249271A5 (de) 1984-11-17 1985-11-15 Verfahren zur herstellung von 9-chlor-1,5-benzothiazepin-derivaten

Country Status (18)

Country Link
US (1) US4665068A (pt)
EP (1) EP0182273B1 (pt)
JP (1) JPS61122281A (pt)
KR (1) KR890003600B1 (pt)
CN (2) CN85101892B (pt)
AT (1) ATE40997T1 (pt)
AU (1) AU578755B2 (pt)
BG (2) BG44379A3 (pt)
CA (1) CA1226281A (pt)
DD (2) DD239202A5 (pt)
DE (1) DE3568428D1 (pt)
DK (1) DK171821B1 (pt)
ES (2) ES8704914A1 (pt)
GB (1) GB2167063A (pt)
HU (1) HU193834B (pt)
NO (1) NO163488C (pt)
PH (1) PH23328A (pt)
PT (1) PT81504B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0256888B1 (en) * 1986-08-20 1991-07-03 McNeilab, Inc. Benzothiazepine vasodilators having aralkyl substitution
IE61939B1 (en) * 1987-07-31 1994-11-30 Tanabe Seiyaku Co Naphthothiazepine derivatives and a process for preparing the same
JPS6450872A (en) * 1987-08-21 1989-02-27 Tanabe Seiyaku Co Production of 1,5-benzothiazepine derivative
JPH01128974A (ja) * 1987-11-13 1989-05-22 Tanabe Seiyaku Co Ltd １，５−ベンゾチアゼピン誘導体の製法
FR2630107B1 (fr) * 1988-04-19 1990-06-08 Synthelabo Procede de preparation du (+) - (2s,3s) (amino-2 phenyl)thio)-3 hydroxy-2 (methoxy-4 phenyl)-3 propionate de methyle
US4902684A (en) * 1988-06-20 1990-02-20 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
FR2637285B1 (fr) * 1988-10-03 1991-04-12 Synthelabo Procede de preparation de derives de l'acide propionique et produits obtenus
IT1230057B (it) * 1989-04-13 1991-09-27 Zambon Spa Processo di risoluzione di intermedi utili per la preparazione di 1,5-benzotiazepine
IL94295A0 (en) * 1989-05-25 1991-03-10 Fujisawa Pharmaceutical Co Thiazepine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
US5001236A (en) * 1989-11-22 1991-03-19 Marion Laboratories, Inc. Benzothiazepines
IT1240651B (it) * 1990-05-17 1993-12-17 Zambon Spa Processo per la risoluzione di derivati glicidici
IT1302261B1 (it) 1998-09-24 2000-09-05 Zambon Spa Processo per la risoluzione cinetica enzimatica di 3-fenilglicidatiper transesterificazione con amminoalcoli

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB296070A (en) * 1927-03-14 1929-04-12 Ass Telephone & Telegraph Co Improvements in or relating to telephone systems
US3075967A (en) * 1961-06-12 1963-01-29 Olin Mathieson Benzothiazines
US3341519A (en) * 1965-04-28 1967-09-12 Squibb & Sons Inc Novel benzoxazines, benzothiazines, benzoxazepins and benzothiazepins
GB1236467A (en) * 1967-10-28 1971-06-23 Tanabe Seiyaku Co Benzothiazepine derivatives
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
KR870000906B1 (ko) * 1982-09-16 1987-05-06 더 뱁콕 앤드 윌콕스 캄패니 과립 제조 기구용 제어장치
US4567175A (en) * 1983-06-03 1986-01-28 Tanabe Seiyaku Co., Ltd. 8-Chloro-1,5-benzothiazepine derivatives
IT1206505B (it) * 1983-07-22 1989-04-27 Schiapparelli Farma Nuovi derivati benzotiazepinonici, metodo per la loro preparazione e composizioni farmaceutiche che licontengono.
US4585768A (en) * 1984-04-10 1986-04-29 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivatives and processes for preparing the same

Also Published As

Publication number Publication date
CA1226281A (en) 1987-09-01
BG44379A3 (en) 1988-11-15
DK530685A (da) 1986-05-18
KR860004039A (ko) 1986-06-16
CN85108458B (zh) 1988-05-25
NO163488C (no) 1990-06-13
AU4933185A (en) 1986-05-22
KR890003600B1 (ko) 1989-09-27
PT81504B (pt) 1987-11-11
JPS61122281A (ja) 1986-06-10
PT81504A (en) 1985-12-01
ES8707723A1 (es) 1987-08-16
DD249271A5 (de) 1987-09-02
DK171821B1 (da) 1997-06-23
JPH0459313B2 (pt) 1992-09-21
ES548898A0 (es) 1987-04-16
AU578755B2 (en) 1988-11-03
GB8429102D0 (en) 1984-12-27
CN85101892A (zh) 1987-01-17
EP0182273B1 (en) 1989-03-01
NO163488B (no) 1990-02-26
ES557079A0 (es) 1987-08-16
EP0182273A1 (en) 1986-05-28
HUT41804A (en) 1987-05-28
US4665068A (en) 1987-05-12
CN85108458A (zh) 1986-07-30
BG44709A3 (bg) 1989-01-16
NO854565L (no) 1986-05-20
ES8704914A1 (es) 1987-04-16
DE3568428D1 (en) 1989-04-06
CN85101892B (zh) 1988-03-02
DK530685D0 (da) 1985-11-15
PH23328A (en) 1989-07-14
HU193834B (en) 1987-12-28
ATE40997T1 (de) 1989-03-15
GB2167063A (en) 1986-05-21

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Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee