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DD201678A5 - Verfahren zur herstellung von 1,5-bis-(1,4-benzodioxin-2-yl)-3-azapentan-1,5-diolen, verfahren zu ihrer herstellung, pharmazeutische praeparate enthaltend diese verbindungen, sowie ihre therapeutische verwendung - Google Patents

Verfahren zur herstellung von 1,5-bis-(1,4-benzodioxin-2-yl)-3-azapentan-1,5-diolen, verfahren zu ihrer herstellung, pharmazeutische praeparate enthaltend diese verbindungen, sowie ihre therapeutische verwendung Download PDF

Info

Publication number
DD201678A5
DD201678A5 DD81234081A DD23408181A DD201678A5 DD 201678 A5 DD201678 A5 DD 201678A5 DD 81234081 A DD81234081 A DD 81234081A DD 23408181 A DD23408181 A DD 23408181A DD 201678 A5 DD201678 A5 DD 201678A5
Authority
DD
German Democratic Republic
Prior art keywords
benzodioxin
dihydro
mixture
formula
compound
Prior art date
Application number
DD81234081A
Other languages
German (de)
English (en)
Inventor
Charles F Huebner
Heinz W Gschwend
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of DD201678A5 publication Critical patent/DD201678A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DD81234081A 1980-10-14 1981-10-14 Verfahren zur herstellung von 1,5-bis-(1,4-benzodioxin-2-yl)-3-azapentan-1,5-diolen, verfahren zu ihrer herstellung, pharmazeutische praeparate enthaltend diese verbindungen, sowie ihre therapeutische verwendung DD201678A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/196,503 US4313955A (en) 1980-10-14 1980-10-14 1,5-Bis(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols

Publications (1)

Publication Number Publication Date
DD201678A5 true DD201678A5 (de) 1983-08-03

Family

ID=22725667

Family Applications (1)

Application Number Title Priority Date Filing Date
DD81234081A DD201678A5 (de) 1980-10-14 1981-10-14 Verfahren zur herstellung von 1,5-bis-(1,4-benzodioxin-2-yl)-3-azapentan-1,5-diolen, verfahren zu ihrer herstellung, pharmazeutische praeparate enthaltend diese verbindungen, sowie ihre therapeutische verwendung

Country Status (21)

Country Link
US (1) US4313955A (pt)
EP (1) EP0050585B1 (pt)
JP (1) JPS5795982A (pt)
KR (1) KR830007618A (pt)
AR (1) AR227441A1 (pt)
AT (1) ATE9694T1 (pt)
AU (1) AU548164B2 (pt)
DD (1) DD201678A5 (pt)
DE (1) DE3166503D1 (pt)
DK (1) DK454181A (pt)
ES (3) ES8303403A1 (pt)
FI (1) FI813154L (pt)
GB (1) GB2085008B (pt)
GR (1) GR75089B (pt)
HU (1) HU187378B (pt)
IE (1) IE51645B1 (pt)
IL (1) IL64033A (pt)
NO (1) NO813446L (pt)
NZ (1) NZ198619A (pt)
PT (1) PT73812B (pt)
ZA (1) ZA817048B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4380653A (en) * 1980-10-14 1983-04-19 Ciba-Geigy Corporation 1,5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols
US4471128A (en) * 1981-09-08 1984-09-11 Ciba-Geigy Corporation 1,5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols
US4654362A (en) * 1983-12-05 1987-03-31 Janssen Pharmaceutica, N.V. Derivatives of 2,2'-iminobisethanol
CA1337429C (en) * 1983-12-05 1995-10-24 Guy Rosalia Eugene Van Lommen Derivatives of 2,2'-iminobisethanol

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1038333A (en) * 1963-02-13 1966-08-10 Ici Ltd Pharmaceutical compositions
US4187313A (en) * 1978-01-30 1980-02-05 Ciba-Geigy Corporation 2-Aminoethyl-1,4-benzodioxans
US4261907A (en) * 1978-01-30 1981-04-14 Ciba-Geigy Corporation Stereospecific process
DE2827801A1 (de) * 1978-06-24 1980-01-10 Kali Chemie Pharma Gmbh Neue n tief 1 -benzoyl-n tief 2 -phenyl-1,3-diaminopropan-2-ole, verfahren zu deren herstellung und arzneimittel
US4212808A (en) * 1979-03-09 1980-07-15 Ciba-Geigy Corporation 2-Oxiranyl-1,4-benzodioxans

Also Published As

Publication number Publication date
PT73812A (en) 1981-11-01
GB2085008B (en) 1984-04-18
AR227441A1 (es) 1982-10-29
IL64033A0 (en) 1982-01-31
GB2085008A (en) 1982-04-21
DK454181A (da) 1982-04-15
DE3166503D1 (en) 1984-11-08
EP0050585B1 (de) 1984-10-03
HU187378B (en) 1985-12-28
JPS5795982A (en) 1982-06-15
IE812399L (en) 1982-04-14
KR830007618A (ko) 1983-11-04
ES8502437A1 (es) 1985-01-01
IL64033A (en) 1984-08-31
AU548164B2 (en) 1985-11-28
ES8600282A1 (es) 1985-10-01
ES506212A0 (es) 1983-02-01
IE51645B1 (en) 1987-01-21
ATE9694T1 (de) 1984-10-15
ES527677A0 (es) 1985-10-01
FI813154L (fi) 1982-04-15
GR75089B (pt) 1984-07-13
NO813446L (no) 1982-04-15
ZA817048B (en) 1982-09-29
ES8303403A1 (es) 1983-02-01
NZ198619A (en) 1985-07-31
EP0050585A1 (de) 1982-04-28
AU7629081A (en) 1982-04-22
US4313955A (en) 1982-02-02
ES516272A0 (es) 1985-01-01
PT73812B (en) 1983-06-20

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