DD134106A5 - Verfahren zur herstellung von 17 beta-hydroxy-4-androsten-3-on-derivaten - Google Patents

Verfahren zur herstellung von 17 beta-hydroxy-4-androsten-3-on-derivaten

Info

Publication number: DD134106A5
Authority: DD; German Democratic Republic
Prior art keywords: androstene; derivatives; preparing; beta hydroxy; beta
Prior art date: 1975-12-19

Application number

DD76204013A

Other languages

English (en)

Inventor

Alfred Weber

Mario Kennecke

Rudolf Mueller

Ulrich Eder

Rudolf Wiechert

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-12-19

Filing date

1976-12-17

Publication date

1979-02-07

1976-12-17 Application filed by Schering Ag filed Critical Schering Ag

1979-02-07 Publication of DD134106A5 publication Critical patent/DD134106A5/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0048—Alkynyl derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/005—Degradation of the lateral chains at position 17
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/832—Bacillus
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/84—Brevibacterium
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/863—Mycobacterium
- Y10S435/866—Mycobacterium smegmatis
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/872—Nocardia
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DD76204013A 1975-12-19 1976-12-17 Verfahren zur herstellung von 17 beta-hydroxy-4-androsten-3-on-derivaten DD134106A5 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2558088A DE2558088C2 (de)	1975-12-19	1975-12-19	Verfahren zur Herstellung von 4-Androsten-3,17-dion-Derivaten

Publications (1)

Publication Number	Publication Date
DD134106A5 true DD134106A5 (de)	1979-02-07

Family

ID=5965329

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DD7600196440A DD129334A5 (de)	1975-12-19	1976-12-17	Verfahren zur herstellung von 4-androsten-3,17-dion-derivaten
DD76204013A DD134106A5 (de)	1975-12-19	1976-12-17	Verfahren zur herstellung von 17 beta-hydroxy-4-androsten-3-on-derivaten

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DD7600196440A DD129334A5 (de)	1975-12-19	1976-12-17	Verfahren zur herstellung von 4-androsten-3,17-dion-derivaten

Country Status (14)

Country	Link
US (1)	US4100027A (de)
JP (1)	JPS5294493A (de)
AT (1)	AT367092B (de)
BE (1)	BE849557A (de)
CH (1)	CH622532A5 (de)
CS (1)	CS187348B2 (de)
DD (2)	DD129334A5 (de)
DE (1)	DE2558088C2 (de)
DK (1)	DK139267C (de)
FR (1)	FR2335522A1 (de)
GB (1)	GB1571913A (de)
HU (1)	HU183022B (de)
IE (1)	IE44515B1 (de)
NL (1)	NL7614024A (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4223092A (en) *	1977-10-21	1980-09-16	The Upjohn Company	Process for preparing 9α-OH BN acid methyl ester
US4383947A (en) *	1981-07-24	1983-05-17	The Upjohn Company	Introduction of a fluorine atom
GB2104526B (en) *	1981-07-24	1985-06-05	Upjohn Co	6-fluoro-9-hydroxyandrost-4-ene-3,17-diones and microbial preparation thereof
US5227375A (en) *	1990-02-08	1993-07-13	Endorecherche, Inc.	Aromatase inhibitors
WO1999007381A1 (en) *	1997-08-11	1999-02-18	Weider Nutrition International, Inc.	Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors
US6071714A (en) *	1998-03-26	2000-06-06	Forbes Medi-Tech, Inc.	Process for the microbial conversion of phytosterols to androstenedione and androstadienedione
DE19827523A1 (de) *	1998-06-22	1999-12-23	Jenapharm Gmbh	Ungesättigte 14,15-Cyclopropano-Androstane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
KR100432054B1 (ko) *	2001-05-11	2004-05-17	(주)유진사이언스	스테롤로부터 4-안드로스텐-3,17-디온/안드로스타-1,4-디엔-3,17-디온으로의 뛰어난 전환능을 가지는 미생물 및 이의 제조방법
BRPI0306736B8 (pt) *	2002-01-21	2021-05-25	Akzo Nobel Nv	processo para a preparação de 7alfa-metilesteróides, e, composto
US20040010138A1 (en) *	2002-03-21	2004-01-15	Schering Ag	Process for the production of 7alpha-methyl steroids
DE10213371C1 (de) *	2002-03-21	2003-12-24	Schering Ag	Verfahren zur Herstellung von 7alpha-Methylsteroiden
AR061892A1 (es) *	2007-07-11	2008-10-01	Consejo Nac Invest Cient Tec	Un compuesto que presenta actividad antiinflamatoria y actividad antiviral, composiciones farmaceuticas que lo comprenden, un procedimiento para su obtencion y uso del mismo en el tratamiento de la queratoconjuntivitis epidemica y de la queratitis estromal herpetica

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1092145A (en) *	1964-06-02	1967-11-22	Noda Inst For Scientific Res	Microbiological conversion of steroids
NL6705450A (de) *	1965-10-22	1968-10-21
US3684657A (en) *	1970-05-11	1972-08-15	Searle & Co	Selective microbiological degradation of steroidal 17-alkyls
US3759791A (en) *	1970-12-10	1973-09-18	Searle & Co	Selective microbiological preparation of androst-4-ene-3,17-dione

1975
- 1975-12-19 DE DE2558088A patent/DE2558088C2/de not_active Expired
1976
- 1976-12-16 DK DK566176A patent/DK139267C/da not_active IP Right Cessation
- 1976-12-16 CH CH1586076A patent/CH622532A5/de not_active IP Right Cessation
- 1976-12-16 US US05/751,687 patent/US4100027A/en not_active Expired - Lifetime
- 1976-12-17 DD DD7600196440A patent/DD129334A5/de unknown
- 1976-12-17 HU HU76SCHE588A patent/HU183022B/hu not_active IP Right Cessation
- 1976-12-17 DD DD76204013A patent/DD134106A5/de unknown
- 1976-12-17 BE BE173399A patent/BE849557A/xx not_active IP Right Cessation
- 1976-12-17 NL NL7614024A patent/NL7614024A/xx not_active Application Discontinuation
- 1976-12-17 AT AT0935676A patent/AT367092B/de not_active IP Right Cessation
- 1976-12-17 CS CS768344A patent/CS187348B2/cs unknown
- 1976-12-20 GB GB53148/76A patent/GB1571913A/en not_active Expired
- 1976-12-20 JP JP15412676A patent/JPS5294493A/ja active Granted
- 1976-12-20 IE IE2786/76A patent/IE44515B1/en unknown
- 1976-12-20 FR FR7638308A patent/FR2335522A1/fr active Granted

Also Published As

Publication number	Publication date
HU183022B (en)	1984-04-28
US4100027A (en)	1978-07-11
IE44515L (en)	1977-06-19
JPS5294493A (en)	1977-08-09
DK139267B (da)	1979-01-22
DE2558088A1 (de)	1977-07-07
CH622532A5 (de)	1981-04-15
GB1571913A (en)	1980-07-23
JPS615715B2 (de)	1986-02-20
NL7614024A (nl)	1977-06-21
FR2335522B1 (de)	1980-07-04
AT367092B (de)	1982-05-25
BE849557A (fr)	1977-06-17
DE2558088C2 (de)	1985-05-30
DK566176A (da)	1977-06-20
DK139267C (da)	1979-06-25
FR2335522A1 (fr)	1977-07-15
DD129334A5 (de)	1978-01-11
IE44515B1 (en)	1981-12-30
ATA935676A (de)	1981-10-15
CS187348B2 (en)	1979-01-31

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