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CY1121658T1 - Πεπτιδια και χρηση αυτων - Google Patents

Πεπτιδια και χρηση αυτων

Info

Publication number
CY1121658T1
CY1121658T1 CY20191100575T CY191100575T CY1121658T1 CY 1121658 T1 CY1121658 T1 CY 1121658T1 CY 20191100575 T CY20191100575 T CY 20191100575T CY 191100575 T CY191100575 T CY 191100575T CY 1121658 T1 CY1121658 T1 CY 1121658T1
Authority
CY
Cyprus
Prior art keywords
amino acids
peptides
arginine
relates
phenylalanine
Prior art date
Application number
CY20191100575T
Other languages
English (en)
Inventor
Deborah O'neil
Derry Mercer
Cedric Charrier
Original Assignee
Novabiotics Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2010/000631 external-priority patent/WO2010112848A2/en
Application filed by Novabiotics Limited filed Critical Novabiotics Limited
Publication of CY1121658T1 publication Critical patent/CY1121658T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Mobile Radio Communication Systems (AREA)

Abstract

Η παρούσα εφεύρεση σχετίζεται με πεπτίδια και τη χρήση τους στη θεραπεία μικροβιακών λοιμώξεων, ιδιαίτερα λοιμώξεων από βακτηρίδια. Συγκεκριμένα, η εφεύρεση αναφέρεται σε πεπτίδια όπου τουλάχιστον το 75% των αμινοξέων του πεπτιδίου είναι αμινοξέα αργινίνης και φαινυλαλανίνης, τουλάχιστον το 50% των αμινοξέων είναι αμινοξέα αργινίνης και τουλάχιστον το 15% των αμινοξέων είναι αμινοξέα φαινυλαλανίνης.
CY20191100575T 2010-03-31 2019-05-30 Πεπτιδια και χρηση αυτων CY1121658T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/GB2010/000631 WO2010112848A2 (en) 2009-03-31 2010-03-31 Inhibition of biofilm organisms
US39008110P 2010-10-05 2010-10-05
GBGB1016733.6A GB201016733D0 (en) 2010-10-05 2010-10-05 Compounds and their use
PCT/GB2011/000480 WO2011121289A2 (en) 2010-03-31 2011-03-30 Compounds and their use

Publications (1)

Publication Number Publication Date
CY1121658T1 true CY1121658T1 (el) 2020-07-31

Family

ID=43243521

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20191100575T CY1121658T1 (el) 2010-03-31 2019-05-30 Πεπτιδια και χρηση αυτων

Country Status (29)

Country Link
US (1) US8901071B2 (el)
EP (3) EP2552434B9 (el)
JP (1) JP5969457B2 (el)
KR (1) KR101922409B1 (el)
CN (1) CN102906105B (el)
AU (3) AU2011234252B2 (el)
BR (1) BR112012024676B1 (el)
CA (1) CA2797437C (el)
CY (1) CY1121658T1 (el)
DK (1) DK2552434T3 (el)
ES (1) ES2729313T3 (el)
GB (1) GB201016733D0 (el)
HR (1) HRP20190982T1 (el)
HU (1) HUE044549T2 (el)
IL (1) IL222027A (el)
LT (1) LT2552434T (el)
MX (1) MX2012011369A (el)
NZ (2) NZ603200A (el)
PL (1) PL2552434T3 (el)
PT (1) PT2552434T (el)
RS (1) RS58980B1 (el)
RU (1) RU2590706C2 (el)
SG (1) SG184138A1 (el)
SI (1) SI2552434T1 (el)
SM (1) SMT201900365T1 (el)
TR (1) TR201908150T4 (el)
UA (1) UA118167C2 (el)
WO (1) WO2011121289A2 (el)
ZA (1) ZA201208173B (el)

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WO2014039014A1 (en) * 2012-09-07 2014-03-13 Agency For Science, Technology And Research Peptides and their uses
US20150119345A1 (en) * 2013-10-29 2015-04-30 Lumena Pharmaceuticals, Inc. Bile acid recycling inhibitors for treatment of gastrointestinal infections
GB2522412A (en) * 2014-01-22 2015-07-29 Agency Science Tech & Res Antimicrobial peptidomimetics
DE102014101663A1 (de) * 2014-02-11 2015-08-13 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Synthetische artifizielle Peptide mit antimikrobieller Wirkung
GB2524777A (en) * 2014-04-02 2015-10-07 Microarray Ltd Dressing comprising electrodes
WO2016054091A1 (en) * 2014-09-29 2016-04-07 The Research Foundation For The State University Of New York Compositions and methods for reducing cutaneous microbiome malodor
KR101781679B1 (ko) * 2014-11-21 2017-09-26 한양대학교 산학협력단 수 처리 물질 및 그 제조 방법
WO2017134661A1 (en) * 2016-02-04 2017-08-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods for disrupting biofilms
WO2018089648A2 (en) 2016-11-09 2018-05-17 Ohio State Innovation Foundation Di-sulfide containing cell penetrating peptides and methods of making and using thereof
US11352394B2 (en) 2016-11-22 2022-06-07 Ohio State Innovation Foundation Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof
US20200071361A1 (en) * 2017-03-03 2020-03-05 Peptilogics, Inc. Engineered antimicrobial amphiphilic peptides and methods of use
US10744313B2 (en) * 2017-07-27 2020-08-18 University Of Utah Research Foundation Therapeutic delivery device
US11865181B2 (en) * 2017-11-03 2024-01-09 Yale University Peptidic materials that traffic efficiently to the cell cytosol and nucleus
US11987647B2 (en) 2018-05-09 2024-05-21 Ohio State Innovation Foundation Cyclic cell-penetrating peptides with one or more hydrophobic residues
CN110227144A (zh) * 2019-06-12 2019-09-13 华懿思科(成都)生物科技有限公司 一种消除妇科炎症致病菌及hpv病毒的抗菌肽靶向制剂及其制备方法
US20230076173A1 (en) * 2020-02-09 2023-03-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Antimicrobial matrix and uses thereof for eliminating microorganisms
CN111533781B (zh) * 2020-03-30 2022-02-08 东北农业大学 非特异受体结合型真菌靶向抗菌肽及其制备方法和应用
US20230287061A1 (en) * 2020-08-10 2023-09-14 Università Cattolica del Sacro Cuore New antimicrobial peptides
CN112586785B (zh) * 2020-12-03 2022-02-08 青岛大学附属医院 一种驴鞭食用胶原蛋白肽-明胶复合胶囊壁材制备方法
RU2771493C1 (ru) * 2021-04-15 2022-05-05 Федеральное государственное бюджетное научное учреждение "Институт экспериментальной медицины" (ФГБНУ "ИЭМ") Пептид, обладающий антибактериальной активностью в отношении микроорганизмов с множественной лекарственной устойчивостью
CN116606347B (zh) * 2023-04-28 2024-03-29 东北农业大学 一种抗菌肽frrffp及其制备方法和应用

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US3703173A (en) 1970-12-31 1972-11-21 Ted A Dixon Nebulizer and tent assembly
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EP0752885B1 (en) 1992-09-25 2003-07-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
GB2408263A (en) * 2003-11-14 2005-05-25 Pacgen Biopharmaceuticals Inc Antimicrobial peptides with reduced hemolysis and methods of their use.
DK1778720T3 (da) 2004-08-18 2010-11-29 Novabiotics Ltd Antimikrobielle peptider omfattende et arginin- og/eller lysinholdigt motiv
AR051489A1 (es) * 2004-11-12 2007-01-17 Novozymes As Polipeptidos que tienen actividad antimicrobiana y polinucleotidos que los codifican
US20070093894A1 (en) * 2005-10-25 2007-04-26 Baylor College Of Medicine Incorporation of antimicrobial combinations onto devices to reduce infection
CN100467481C (zh) * 2006-04-18 2009-03-11 河北师范大学 棕点湍蛙抗菌多肽及其在制药中的应用
CN101070341A (zh) * 2006-05-08 2007-11-14 徐永强 无致突变作用的抗菌多肽
PL2061886T3 (pl) * 2006-08-21 2014-10-31 Univ British Columbia Małe kationowe peptydy immunomodulujące
GB0702021D0 (en) 2007-02-02 2007-03-14 Novabiotics Ltd Peptides and their use
CN101168564B (zh) * 2007-10-22 2012-03-21 中国科学院昆明动物研究所 人源性抗菌肽及其衍生物的用途
EP2168590A1 (en) * 2008-09-24 2010-03-31 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Antimicrobial peptides
GB0905451D0 (en) * 2009-03-31 2009-05-13 Novabiotics Ltd Biofilms

Also Published As

Publication number Publication date
HUE044549T2 (hu) 2019-11-28
BR112012024676A2 (pt) 2016-06-07
AU2011234252B2 (en) 2016-05-12
RU2012145756A (ru) 2014-05-10
ZA201208173B (en) 2013-07-31
EP3578193A3 (en) 2020-05-20
CA2797437C (en) 2017-11-07
CA2797437A1 (en) 2011-10-06
IL222027A (en) 2016-11-30
UA118167C2 (uk) 2018-12-10
CN102906105B (zh) 2017-05-10
SMT201900365T1 (it) 2019-07-11
NZ603200A (en) 2014-02-28
EP3578193B1 (en) 2023-09-06
US20130102524A1 (en) 2013-04-25
JP5969457B2 (ja) 2016-08-17
BR112012024676B1 (pt) 2022-05-03
EP2552434A2 (en) 2013-02-06
PT2552434T (pt) 2019-06-12
US8901071B2 (en) 2014-12-02
AU2018202201A1 (en) 2018-04-26
DK2552434T3 (da) 2019-06-11
LT2552434T (lt) 2019-07-25
HRP20190982T1 (hr) 2019-10-18
RU2590706C2 (ru) 2016-07-10
AU2016208308A1 (en) 2016-08-11
EP3578193C0 (en) 2023-09-06
NZ618571A (en) 2015-02-27
JP2013523703A (ja) 2013-06-17
CN102906105A (zh) 2013-01-30
EP2552434B9 (en) 2019-09-11
ES2729313T3 (es) 2019-10-31
AU2011234252A1 (en) 2012-11-22
EP3479824A2 (en) 2019-05-08
WO2011121289A3 (en) 2012-03-15
PL2552434T3 (pl) 2019-09-30
GB201016733D0 (en) 2010-11-17
EP2552434B1 (en) 2019-05-08
AU2016208308B2 (en) 2018-01-18
KR101922409B1 (ko) 2018-11-27
EP3479824A3 (en) 2019-08-14
EP3578193A2 (en) 2019-12-11
AU2018202201B2 (en) 2019-12-05
SG184138A1 (en) 2012-10-30
WO2011121289A2 (en) 2011-10-06
MX2012011369A (es) 2012-11-30
TR201908150T4 (tr) 2019-06-21
SI2552434T1 (sl) 2019-08-30
RS58980B1 (sr) 2019-08-30
KR20130043625A (ko) 2013-04-30

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