[go: up one dir, main page]

CY1119532T1 - (S) -PYRILDOL AND THE PHARMACEUTALLY ACCEPTABLE SALTS FOR USE IN MEDICINE - Google Patents

(S) -PYRILDOL AND THE PHARMACEUTALLY ACCEPTABLE SALTS FOR USE IN MEDICINE

Info

Publication number
CY1119532T1
CY1119532T1 CY20171101123T CY171101123T CY1119532T1 CY 1119532 T1 CY1119532 T1 CY 1119532T1 CY 20171101123 T CY20171101123 T CY 20171101123T CY 171101123 T CY171101123 T CY 171101123T CY 1119532 T1 CY1119532 T1 CY 1119532T1
Authority
CY
Cyprus
Prior art keywords
acceptable salts
pyrildol
medicine
pharmaceutally acceptable
pharmaceutally
Prior art date
Application number
CY20171101123T
Other languages
Greek (el)
Inventor
Augusto Eugénio PARDAL FILIPE
Pedro Filipe EUFRÁSIO PEDROSO
Susana Marques ALMEIDA PECORELLI
Carlos Alberto Eufrásio CASIMIRO CAIXADO
Ana Sofia da Conceição LOPES
João Carlos DAMIL
Original Assignee
Tecnimede-Sociedade Tecnico-Medicinal, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tecnimede-Sociedade Tecnico-Medicinal, S.A. filed Critical Tecnimede-Sociedade Tecnico-Medicinal, S.A.
Publication of CY1119532T1 publication Critical patent/CY1119532T1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

(S)-πιρλινδόλη ή τα φαρμακευτικώς αποδεκτά άλατα αυτής, καθώς και φαρμακευτικές συνθέσεις που περιλαμβάνουν αυτήν(ά) για χρήση στη θεραπευτική αγωγή και πρόληψη πόνου.(S) -pyrindol or its pharmaceutically acceptable salts, and pharmaceutical compositions comprising it (s) for use in the treatment and prevention of pain.

CY20171101123T 2014-05-09 2017-10-30 (S) -PYRILDOL AND THE PHARMACEUTALLY ACCEPTABLE SALTS FOR USE IN MEDICINE CY1119532T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/PT2014/000029 WO2015171005A1 (en) 2014-05-09 2014-05-09 (s)-pirlindole or its pharmaceutically acceptable salts for use in medicine

Publications (1)

Publication Number Publication Date
CY1119532T1 true CY1119532T1 (en) 2018-03-07

Family

ID=50819931

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20171101123T CY1119532T1 (en) 2014-05-09 2017-10-30 (S) -PYRILDOL AND THE PHARMACEUTALLY ACCEPTABLE SALTS FOR USE IN MEDICINE

Country Status (30)

Country Link
US (1) US9814712B2 (en)
EP (1) EP3057589B1 (en)
JP (1) JP6768520B2 (en)
KR (1) KR102298676B1 (en)
CN (1) CN106456637B (en)
AU (1) AU2014393490B2 (en)
CA (1) CA2948598C (en)
CY (1) CY1119532T1 (en)
DK (1) DK3057589T3 (en)
EC (1) ECSP16086247A (en)
ES (1) ES2649492T3 (en)
HR (1) HRP20171651T1 (en)
HU (1) HUE035071T2 (en)
IL (1) IL248855B (en)
LT (1) LT3057589T (en)
MA (1) MA39447B1 (en)
MX (1) MX368734B (en)
NO (1) NO3057589T3 (en)
NZ (1) NZ726132A (en)
PH (1) PH12016502233A1 (en)
PL (1) PL3057589T3 (en)
PT (1) PT3057589T (en)
RS (1) RS56591B1 (en)
RU (1) RU2695647C2 (en)
SA (1) SA516380264B1 (en)
SI (1) SI3057589T1 (en)
SM (1) SMT201700519T1 (en)
TN (1) TN2016000498A1 (en)
UA (1) UA118474C2 (en)
WO (1) WO2015171005A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX368735B (en) * 2014-05-09 2019-10-14 Tecnimede Sociedade Tecnico Medicinal S (R) -PIRLINDOL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS FOR USE IN MEDICINE.
FI3831385T3 (en) * 2014-05-09 2024-09-04 Tecnimede Sociedade Tecnico Medicinal S Mandelate salts of pirlindole enantiomers for use in medicine
EP3392250A1 (en) * 2017-04-21 2018-10-24 Tecnimede-Sociedade Tecnico-Medicinal, S.A. Process for the preparation of piperazine ring for the synthesis of pyrazinocarbazole derivatives
EP3392251A1 (en) 2017-04-21 2018-10-24 Tecnimede-Sociedade Tecnico-Medicinal, S.A. Process for the preparation of pirlindole enantiomers and its salts
MX2018011142A (en) 2018-09-13 2019-10-10 Federico Amezcua Amezcua A synergistic pharmaceutical combination of a selective cyclloxygenasa-2 inhibitor and an antraquinone derivative.
EP3900716A1 (en) * 2020-04-21 2021-10-27 Dompe' Farmaceutici S.P.A. Co-crystal of gabapentin, ketoprofen and lysine, pharmaceutical compositions and their medical use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05003550A (en) * 2002-10-03 2006-01-24 Cypress Bioscience Inc Dosage escalation and divided daily dose of anti-depressants to treat neurological disorders.
JP2006525226A (en) * 2002-12-24 2006-11-09 ニューロケム (インターナショナル) リミテッド Therapeutic formulations for the treatment of β-amyloid related diseases
WO2005025550A1 (en) * 2003-09-15 2005-03-24 Vectura Limited Pharmaceutical compositions for treating premature ejaculation by pulmonary inhalation
EP1688161A1 (en) * 2004-11-02 2006-08-09 Switch Biotech Aktiengesellschaft Use of pirlindole for the treatment of diseases which are characterized by proliferation of t-lymphocytes and/or hyperproliferation of keratinocytes in particular atopic dermatitis and psoriasis
FI3831385T3 (en) * 2014-05-09 2024-09-04 Tecnimede Sociedade Tecnico Medicinal S Mandelate salts of pirlindole enantiomers for use in medicine

Also Published As

Publication number Publication date
MX368734B (en) 2019-10-14
ES2649492T3 (en) 2018-01-12
HUE035071T2 (en) 2018-05-02
EP3057589A1 (en) 2016-08-24
SA516380264B1 (en) 2019-07-29
NZ726132A (en) 2019-02-22
PT3057589T (en) 2017-11-29
IL248855B (en) 2020-05-31
SI3057589T1 (en) 2017-12-29
HRP20171651T1 (en) 2017-12-15
PL3057589T3 (en) 2018-01-31
JP6768520B2 (en) 2020-10-14
CN106456637B (en) 2020-06-09
TN2016000498A1 (en) 2018-04-04
US20170143709A1 (en) 2017-05-25
AU2014393490A1 (en) 2016-11-24
JP2017518979A (en) 2017-07-13
RS56591B1 (en) 2018-02-28
EP3057589B1 (en) 2017-08-02
WO2015171005A1 (en) 2015-11-12
KR20170002434A (en) 2017-01-06
MA39447A1 (en) 2017-10-31
RU2016148183A (en) 2018-06-13
MA39447B1 (en) 2018-05-31
CA2948598C (en) 2021-06-08
LT3057589T (en) 2017-11-27
RU2695647C2 (en) 2019-07-25
IL248855A0 (en) 2017-01-31
CN106456637A (en) 2017-02-22
AU2014393490B2 (en) 2020-01-02
DK3057589T3 (en) 2017-11-13
UA118474C2 (en) 2019-01-25
US9814712B2 (en) 2017-11-14
ECSP16086247A (en) 2017-02-24
CA2948598A1 (en) 2015-11-12
RU2016148183A3 (en) 2018-06-13
MX2016014699A (en) 2017-05-02
PH12016502233A1 (en) 2017-02-06
NO3057589T3 (en) 2017-12-30
KR102298676B1 (en) 2021-09-07
SMT201700519T1 (en) 2018-01-11

Similar Documents

Publication Publication Date Title
CY1125205T1 (en) ACTIVE PHARMACEUTICAL COMPOSITIONS FROM THE THERAPEUTIC POINT OF VIEW OF COMPOUNDS
MX2016012574A (en) Substituted heteroaryl compounds and methods of use.
MX378273B (en) ACTIVE COMPOUNDS TOWARDS BROMODOMAINS.
GB2541571A (en) Pharmaceutical compositions
GB201411465D0 (en) Active pharmaceutical ingredient (api) comprising cannabinoids for use in the treatment of cancer
TW201613919A (en) Inhibitors of Bruton's tyrosine kinase
WO2015160975A3 (en) Combination of a pi3k inhibitor with a bcl-2 inhibitor for use in the treatment of cancer
CY1119532T1 (en) (S) -PYRILDOL AND THE PHARMACEUTALLY ACCEPTABLE SALTS FOR USE IN MEDICINE
CL2016001918A1 (en) Heteroaryl amides as protein aggregation inhibitors
MX2017002489A (en) Human therapeutic agents.
PH12015502616A1 (en) Pharmaceutical combination comprising metformin and dihydroquercetin and its use for the treatment of cancer
WO2015171558A3 (en) BENZENESULFONAMIDO AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORγ AND THE TREATEMENT OF DISEASE
EA201692111A1 (en) PHARMACEUTICAL COMPOSITIONS CONTAINING DANIRYXIN FOR TREATING INFECTIOUS DISEASES
MA50358A (en) SEMAGLUTIDE IN MEDICAL THERAPY
TW201713323A (en) Therapeutic compositions and methods of use thereof
MX2017013047A (en) Treatment of pain.
CY1119522T1 (en) (R) - PILINDOL AND THE PHARMACEUTICALALLY ACCEPTABLE SALTS FOR USE IN MEDICINE
HK1243327A1 (en) Combination comprising spirulina and palmitoylethanolamide and/or salts or pharmaceutically acceptable derivatives thereof and their formulations, for use in the prevention and/or in the treatment of hyperactivated tissue conditions
MX2015013755A (en) Pharmaceutical formulation for use in the treatment and/or prevention of restenosis.
IL249860A0 (en) Pharmaceutical compositions, methods for their preparation and their use in the treatment of cancer
HK1251476A1 (en) Aminothiolester compounds or pharmaceutically acceptable salts thereof, for use in the treatment of cancer
SG10201903630UA (en) Iminosugars useful for the treatment of viral diseases
EA201790020A1 (en) COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND THEIR APPLICATION IN THE TREATMENT OF NEURODEGENERATIVE DISEASES
GB2546703A (en) Compounds
EA201692164A1 (en) MEDICINE FOR THE TREATMENT OF PATIENTS WITH TINNITUS