CY1118918T1 - Παραγοντες εξαλειψης κυτταρων β, οπως αντισωματα enanti-cd20 ή θραυσματα αυτων για την αντιμετωπιση συνδρομου χρονιας κοπωσης - Google Patents
Παραγοντες εξαλειψης κυτταρων β, οπως αντισωματα enanti-cd20 ή θραυσματα αυτων για την αντιμετωπιση συνδρομου χρονιας κοπωσηςInfo
- Publication number
- CY1118918T1 CY1118918T1 CY20171100535T CY171100535T CY1118918T1 CY 1118918 T1 CY1118918 T1 CY 1118918T1 CY 20171100535 T CY20171100535 T CY 20171100535T CY 171100535 T CY171100535 T CY 171100535T CY 1118918 T1 CY1118918 T1 CY 1118918T1
- Authority
- CY
- Cyprus
- Prior art keywords
- chronic fatigue
- fragments
- treatment
- antibodies
- enanti
- Prior art date
Links
- 206010008874 Chronic Fatigue Syndrome Diseases 0.000 title abstract 4
- 208000029766 myalgic encephalomeyelitis/chronic fatigue syndrome Diseases 0.000 title abstract 4
- 239000012634 fragment Substances 0.000 title abstract 2
- 210000003719 b-lymphocyte Anatomy 0.000 title 1
- 230000008033 biological extinction Effects 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 206010057244 Post viral fatigue syndrome Diseases 0.000 abstract 2
- 230000027530 B cell deletion Effects 0.000 abstract 1
- 102100022005 B-lymphocyte antigen CD20 Human genes 0.000 abstract 1
- 229940124292 CD20 monoclonal antibody Drugs 0.000 abstract 1
- 101000897405 Homo sapiens B-lymphocyte antigen CD20 Proteins 0.000 abstract 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 abstract 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 206010016256 fatigue Diseases 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται σε ένα πρώτο θέμα με ένα έναντι-CD20 αντίσωμα εξάλειψης κυττάρων Β ή ένα θραύσμα αντισώματος αυτού πρόσδεσης CD20 για την αντιμετώπιση συνδρόμου χρόνιας κόπωσης και μυαλγικής εγκεφαλομυελίτιδας. Ιδιαίτερα, η παρούσα εφεύρεση σχετίζεται με τη χρήση μονοκλωνικών αντισωμάτων έναντι-CD20 ή θραυσμάτων αυτών τα οποία κατά προτίμηση είναι ανθρωποποιημένα για την αντιμετώπιση συνδρόμου χρόνιας κόπωσης/μυαλγικής εγκεφαλομυελίτιδας σε ένα υποκείμενο που έχει πληγεί από την προαναφερθείσα νόσο.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1855108P | 2008-01-02 | 2008-01-02 | |
EP08000006A EP2077281A1 (en) | 2008-01-02 | 2008-01-02 | Anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome |
PCT/EP2009/000003 WO2009083602A1 (en) | 2008-01-02 | 2009-01-02 | B-cell depleting agents, like anti-cd20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome |
EP09700128.3A EP2235060B1 (en) | 2008-01-02 | 2009-01-02 | B-cell depleting agents, like anti-cd20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1118918T1 true CY1118918T1 (el) | 2018-01-10 |
Family
ID=39402622
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20171100535T CY1118918T1 (el) | 2008-01-02 | 2017-05-22 | Παραγοντες εξαλειψης κυτταρων β, οπως αντισωματα enanti-cd20 ή θραυσματα αυτων για την αντιμετωπιση συνδρομου χρονιας κοπωσης |
Country Status (19)
Country | Link |
---|---|
EP (2) | EP2077281A1 (el) |
JP (1) | JP5722044B2 (el) |
KR (1) | KR101652530B1 (el) |
CN (1) | CN101910201B (el) |
AU (1) | AU2009203117B2 (el) |
BR (1) | BRPI0906172A2 (el) |
CA (1) | CA2706899C (el) |
CY (1) | CY1118918T1 (el) |
DK (1) | DK2235060T3 (el) |
ES (1) | ES2625728T3 (el) |
HR (1) | HRP20170687T1 (el) |
HU (1) | HUE034127T2 (el) |
IL (1) | IL206767A (el) |
LT (1) | LT2235060T (el) |
PL (1) | PL2235060T3 (el) |
PT (1) | PT2235060T (el) |
RU (1) | RU2519229C2 (el) |
SI (1) | SI2235060T1 (el) |
WO (1) | WO2009083602A1 (el) |
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IN2012DN06309A (el) * | 2010-01-11 | 2015-09-25 | Alexion Pharma Inc | |
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EP2805730A1 (en) * | 2013-05-21 | 2014-11-26 | Bergen Teknologioverforing AS | Nitric oxide donor for the treatment of chronic fatigue syndrome |
EP3062780A1 (en) * | 2013-11-01 | 2016-09-07 | Bergen Teknologioverføring AS | Activators or stimulators of soluble guanylate cyclase for use in treating chronic fatigue syndrome |
WO2016102530A1 (en) * | 2014-12-22 | 2016-06-30 | Bergen Teknologioverføring As | Cyclic phosphoric acid derivative for the treatment of chronic fatigue syndrome |
WO2019126536A1 (en) | 2017-12-20 | 2019-06-27 | Alexion Pharmaceuticals Inc. | Humanized anti-cd200 antibodies and uses thereof |
US12139533B2 (en) | 2017-12-20 | 2024-11-12 | Alexion Pharmaceuticals, Inc. | Liquid formulations of anti-CD200 antibodies |
KR102721494B1 (ko) * | 2018-04-17 | 2024-10-24 | 국립암센터 | 고갈성 항 cd4 단일클론항체를 포함하는 항암 t 세포치료제 보조용 조성물 및 이의 용도 |
EP3569617A1 (en) * | 2018-05-18 | 2019-11-20 | Trion Research GmbH | Pharmaceutical preparation for use in treating epstein- barr virus positive patients with reactivation phenomenon- associated diseases |
JP2022546686A (ja) | 2019-08-30 | 2022-11-07 | ベストランデツ イノバシオンセルスカップ アーエス | 形質細胞に対する抑制剤または細胞傷害剤を使用する慢性疲労症候群の処置のための方法 |
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JP6088723B2 (ja) * | 2005-11-23 | 2017-03-01 | ジェネンテック, インコーポレイテッド | B細胞アッセイに関する組成物及び方法。 |
-
2008
- 2008-01-02 EP EP08000006A patent/EP2077281A1/en not_active Withdrawn
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2009
- 2009-01-02 HU HUE09700128A patent/HUE034127T2/en unknown
- 2009-01-02 SI SI200931662T patent/SI2235060T1/sl unknown
- 2009-01-02 PT PT97001283T patent/PT2235060T/pt unknown
- 2009-01-02 HR HRP20170687TT patent/HRP20170687T1/hr unknown
- 2009-01-02 RU RU2010132178/15A patent/RU2519229C2/ru active
- 2009-01-02 CN CN200980101646.6A patent/CN101910201B/zh not_active Expired - Fee Related
- 2009-01-02 WO PCT/EP2009/000003 patent/WO2009083602A1/en active Application Filing
- 2009-01-02 CA CA2706899A patent/CA2706899C/en not_active Expired - Fee Related
- 2009-01-02 DK DK09700128.3T patent/DK2235060T3/en active
- 2009-01-02 AU AU2009203117A patent/AU2009203117B2/en not_active Ceased
- 2009-01-02 KR KR1020107014813A patent/KR101652530B1/ko not_active Expired - Fee Related
- 2009-01-02 JP JP2010541057A patent/JP5722044B2/ja not_active Expired - Fee Related
- 2009-01-02 BR BRPI0906172-0A patent/BRPI0906172A2/pt not_active Application Discontinuation
- 2009-01-02 PL PL09700128T patent/PL2235060T3/pl unknown
- 2009-01-02 LT LTEP09700128.3T patent/LT2235060T/lt unknown
- 2009-01-02 EP EP09700128.3A patent/EP2235060B1/en active Active
- 2009-01-02 ES ES09700128.3T patent/ES2625728T3/es active Active
-
2010
- 2010-07-01 IL IL206767A patent/IL206767A/en active IP Right Grant
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- 2017-05-22 CY CY20171100535T patent/CY1118918T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU2009203117A1 (en) | 2009-07-09 |
PT2235060T (pt) | 2017-05-31 |
AU2009203117B2 (en) | 2014-10-23 |
IL206767A0 (en) | 2010-12-30 |
BRPI0906172A2 (pt) | 2015-06-30 |
RU2010132178A (ru) | 2012-02-10 |
KR101652530B1 (ko) | 2016-08-30 |
JP5722044B2 (ja) | 2015-05-20 |
DK2235060T3 (en) | 2017-06-06 |
CN101910201A (zh) | 2010-12-08 |
HRP20170687T1 (hr) | 2017-09-08 |
HUE034127T2 (en) | 2018-01-29 |
CA2706899C (en) | 2017-02-28 |
ES2625728T3 (es) | 2017-07-20 |
WO2009083602A1 (en) | 2009-07-09 |
CA2706899A1 (en) | 2009-07-09 |
EP2235060B1 (en) | 2017-03-29 |
EP2235060A1 (en) | 2010-10-06 |
KR20100116172A (ko) | 2010-10-29 |
SI2235060T1 (sl) | 2017-09-29 |
RU2519229C2 (ru) | 2014-06-10 |
JP2011508754A (ja) | 2011-03-17 |
PL2235060T3 (pl) | 2017-10-31 |
EP2077281A1 (en) | 2009-07-08 |
CN101910201B (zh) | 2015-01-21 |
LT2235060T (lt) | 2017-07-25 |
IL206767A (en) | 2015-03-31 |
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