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CY1114922T1 - Κυτταροτοξικοι παραγοντες οι οποιοι περιλαμβανουν νεα παραγωγα τομαϋμυκινης και τη θεραπευτικη τους χρηση - Google Patents

Κυτταροτοξικοι παραγοντες οι οποιοι περιλαμβανουν νεα παραγωγα τομαϋμυκινης και τη θεραπευτικη τους χρηση

Info

Publication number
CY1114922T1
CY1114922T1 CY20131101083T CY131101083T CY1114922T1 CY 1114922 T1 CY1114922 T1 CY 1114922T1 CY 20131101083 T CY20131101083 T CY 20131101083T CY 131101083 T CY131101083 T CY 131101083T CY 1114922 T1 CY1114922 T1 CY 1114922T1
Authority
CY
Cyprus
Prior art keywords
derivatives
therapeutic use
tomomycin
cytotoxic agents
include new
Prior art date
Application number
CY20131101083T
Other languages
English (en)
Inventor
Laurence Gauzy
Hervé Bouchard
Alain Commerçon
Yonghong Deng
Ravi Vj Chari
Original Assignee
Sanofi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39048765&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1114922(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi filed Critical Sanofi
Publication of CY1114922T1 publication Critical patent/CY1114922T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Η παρούσα εφεύρεση σχετίζεται με νέα παράγωγα τομαϋμυκίνης τα οποία διαθέτουν μια αλυσίδα σύνδεσης μεταξύ δυο μονάδων πυρρολο[2,1c][1,4]βενζοδιαζεπινών, υποκατεστημένα από έναν μη διασπασμένο συνδέτη και τα συζευγμένα προϊόντα τους στους παράγοντες κυτταρικής πρόσδεσης, τη διαδικασία παρασκευής τους και τη θεραπευτική τους χρήση.
CY20131101083T 2007-07-19 2013-12-03 Κυτταροτοξικοι παραγοντες οι οποιοι περιλαμβανουν νεα παραγωγα τομαϋμυκινης και τη θεραπευτικη τους χρηση CY1114922T1 (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07290904.7A EP2019104B1 (en) 2007-07-19 2007-07-19 Cytotoxic agents comprising new tomaymycin derivatives and their therapeutic use

Publications (1)

Publication Number Publication Date
CY1114922T1 true CY1114922T1 (el) 2016-12-14

Family

ID=39048765

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20121100093T CY1112278T1 (el) 2007-07-19 2012-01-26 Κυτταροτοξικοι παραγοντες που περιεχουν νεα παραγωγα τομαυμυciν και η θεραπευτικη χρηση τους
CY20131101083T CY1114922T1 (el) 2007-07-19 2013-12-03 Κυτταροτοξικοι παραγοντες οι οποιοι περιλαμβανουν νεα παραγωγα τομαϋμυκινης και τη θεραπευτικη τους χρηση

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20121100093T CY1112278T1 (el) 2007-07-19 2012-01-26 Κυτταροτοξικοι παραγοντες που περιεχουν νεα παραγωγα τομαυμυciν και η θεραπευτικη χρηση τους

Country Status (40)

Country Link
US (1) US8404678B2 (el)
EP (2) EP2019104B1 (el)
JP (1) JP5551070B2 (el)
KR (1) KR101627871B1 (el)
CN (1) CN101784550B (el)
AR (1) AR067575A1 (el)
AT (1) ATE530553T1 (el)
AU (1) AU2008281439B2 (el)
BR (1) BRPI0814267A2 (el)
CA (1) CA2693551C (el)
CL (1) CL2008002139A1 (el)
CO (1) CO6290692A2 (el)
CR (1) CR11225A (el)
CY (2) CY1112278T1 (el)
DK (2) DK2019104T3 (el)
DO (1) DOP2010000014A (el)
EA (1) EA019938B1 (el)
EC (1) ECSP109875A (el)
ES (2) ES2435779T3 (el)
GT (1) GT201000008A (el)
HK (1) HK1144289A1 (el)
HR (1) HRP20120067T1 (el)
IL (1) IL203318A (el)
JO (1) JO2744B1 (el)
MA (1) MA31617B1 (el)
ME (1) ME00969B (el)
MY (1) MY151245A (el)
NI (1) NI201000005A (el)
NZ (1) NZ582679A (el)
PA (1) PA8790201A1 (el)
PE (2) PE20090889A1 (el)
PL (2) PL2019104T3 (el)
PT (2) PT2019104E (el)
RS (1) RS52245B (el)
SI (2) SI2019104T1 (el)
TN (1) TN2010000002A1 (el)
TW (1) TWI500618B (el)
UA (1) UA98153C2 (el)
WO (1) WO2009016516A2 (el)
ZA (1) ZA201000389B (el)

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