CY1113499T1 - Ενωσεις θειαζολυλο-πυραζολοπυριμιδινης ως συνθετικα ενδιαμεσα και σχετικες συνθετικες διεργασιες - Google Patents
Ενωσεις θειαζολυλο-πυραζολοπυριμιδινης ως συνθετικα ενδιαμεσα και σχετικες συνθετικες διεργασιεςInfo
- Publication number
- CY1113499T1 CY1113499T1 CY20121101263T CY121101263T CY1113499T1 CY 1113499 T1 CY1113499 T1 CY 1113499T1 CY 20121101263 T CY20121101263 T CY 20121101263T CY 121101263 T CY121101263 T CY 121101263T CY 1113499 T1 CY1113499 T1 CY 1113499T1
- Authority
- CY
- Cyprus
- Prior art keywords
- synthetic
- thaizolyl
- pyrazolopyrimidine compounds
- intermediates
- procedures
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Addiction (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με ένα συνθετικό ενδιάμεσο με τον Τύπο (Ι) και τη χρήση του σε μία συνθετική διεργασία ώστε να κατασκευαστούν ενώσεις με τον Τύπο (ΙΙ).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10215308P | 2008-10-02 | 2008-10-02 | |
| EP09736733A EP2350079B1 (en) | 2008-10-02 | 2009-09-29 | Thiazolyl-pyrazolopyrimidine compounds as synthetic intermediates and related synthetic processes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1113499T1 true CY1113499T1 (el) | 2016-06-22 |
Family
ID=41507435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20121101263T CY1113499T1 (el) | 2008-10-02 | 2012-12-27 | Ενωσεις θειαζολυλο-πυραζολοπυριμιδινης ως συνθετικα ενδιαμεσα και σχετικες συνθετικες διεργασιες |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8563718B2 (el) |
| EP (1) | EP2350079B1 (el) |
| JP (1) | JP5524221B2 (el) |
| KR (1) | KR101357392B1 (el) |
| CN (1) | CN102171212A (el) |
| AR (1) | AR073708A1 (el) |
| AU (1) | AU2009298757B2 (el) |
| BR (1) | BRPI0920838A2 (el) |
| CA (1) | CA2739422C (el) |
| CY (1) | CY1113499T1 (el) |
| DK (1) | DK2350079T3 (el) |
| EA (1) | EA018807B1 (el) |
| ES (1) | ES2397509T3 (el) |
| HR (1) | HRP20120961T1 (el) |
| IL (1) | IL211292A (el) |
| MX (1) | MX2011003529A (el) |
| PL (1) | PL2350079T3 (el) |
| PT (1) | PT2350079E (el) |
| SI (1) | SI2350079T1 (el) |
| TW (1) | TWI432435B (el) |
| WO (1) | WO2010039678A1 (el) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112020002967A2 (pt) | 2017-08-14 | 2020-08-11 | Spruce Biosciences, Inc. | antagonistas de receptor de fator de liberação de corticotropina |
| JP7285222B2 (ja) * | 2017-08-14 | 2023-06-01 | スプルース バイオサイエンシズ インコーポレイテッド | 副腎皮質刺激ホルモン放出因子受容体拮抗薬 |
| IL300478A (en) | 2020-08-12 | 2023-04-01 | Spruce Biosciences Inc | Methods and preparations for the treatment of polycystic ovary syndrome |
| US11708372B2 (en) | 2021-11-19 | 2023-07-25 | Spruce Biosciences, Inc. | Crystalline composition of tildacerfont and methods of use and preparation thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE161178T1 (de) * | 1992-06-10 | 1998-01-15 | Fujisawa Pharmaceutical Co | Pyrazolpyridine für die behandlung der anämie |
| ES2350282T3 (es) | 2006-09-20 | 2011-01-20 | Eli Lilly And Company | Tiazol pirazolopirimidinas como antagonistas del receptor de crf1. |
| US8952207B2 (en) * | 2007-09-11 | 2015-02-10 | The University Of Houston System | Copper-catalyzed C—H bond arylation |
-
2009
- 2009-09-29 PL PL09736733T patent/PL2350079T3/pl unknown
- 2009-09-29 SI SI200930463T patent/SI2350079T1/sl unknown
- 2009-09-29 TW TW098132999A patent/TWI432435B/zh not_active IP Right Cessation
- 2009-09-29 CN CN2009801388897A patent/CN102171212A/zh active Pending
- 2009-09-29 KR KR1020117007555A patent/KR101357392B1/ko not_active Expired - Fee Related
- 2009-09-29 EP EP09736733A patent/EP2350079B1/en active Active
- 2009-09-29 DK DK09736733.8T patent/DK2350079T3/da active
- 2009-09-29 AU AU2009298757A patent/AU2009298757B2/en not_active Ceased
- 2009-09-29 WO PCT/US2009/058722 patent/WO2010039678A1/en active Application Filing
- 2009-09-29 CA CA2739422A patent/CA2739422C/en active Active
- 2009-09-29 EA EA201170526A patent/EA018807B1/ru not_active IP Right Cessation
- 2009-09-29 US US13/063,226 patent/US8563718B2/en active Active
- 2009-09-29 MX MX2011003529A patent/MX2011003529A/es active IP Right Grant
- 2009-09-29 ES ES09736733T patent/ES2397509T3/es active Active
- 2009-09-29 AR ARP090103753A patent/AR073708A1/es not_active Application Discontinuation
- 2009-09-29 PT PT97367338T patent/PT2350079E/pt unknown
- 2009-09-29 BR BRPI0920838A patent/BRPI0920838A2/pt not_active IP Right Cessation
- 2009-09-29 JP JP2011530133A patent/JP5524221B2/ja active Active
-
2011
- 2011-02-17 IL IL211292A patent/IL211292A/en not_active IP Right Cessation
-
2012
- 2012-11-23 HR HRP20120961AT patent/HRP20120961T1/hr unknown
- 2012-12-27 CY CY20121101263T patent/CY1113499T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL211292A0 (en) | 2011-04-28 |
| PT2350079E (pt) | 2012-12-20 |
| IL211292A (en) | 2013-06-27 |
| TW201018692A (en) | 2010-05-16 |
| DK2350079T3 (da) | 2012-12-17 |
| WO2010039678A1 (en) | 2010-04-08 |
| BRPI0920838A2 (pt) | 2018-10-16 |
| AU2009298757A1 (en) | 2010-04-08 |
| ES2397509T3 (es) | 2013-03-07 |
| AU2009298757B2 (en) | 2013-08-01 |
| EA201170526A1 (ru) | 2011-10-31 |
| PL2350079T3 (pl) | 2013-03-29 |
| KR20110063513A (ko) | 2011-06-10 |
| JP2012504626A (ja) | 2012-02-23 |
| TWI432435B (zh) | 2014-04-01 |
| US20110166345A1 (en) | 2011-07-07 |
| AR073708A1 (es) | 2010-11-24 |
| EP2350079A1 (en) | 2011-08-03 |
| JP5524221B2 (ja) | 2014-06-18 |
| CA2739422A1 (en) | 2010-04-08 |
| KR101357392B1 (ko) | 2014-02-03 |
| US8563718B2 (en) | 2013-10-22 |
| CA2739422C (en) | 2013-03-12 |
| EA018807B1 (ru) | 2013-10-30 |
| SI2350079T1 (sl) | 2013-02-28 |
| EP2350079B1 (en) | 2012-11-14 |
| HRP20120961T1 (hr) | 2012-12-31 |
| MX2011003529A (es) | 2011-04-21 |
| CN102171212A (zh) | 2011-08-31 |
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