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CY1110132T1 - Παραγωγα ουριας τροπανιου, η παρασκευη τους και οι εφαρμογες τους στη θεραπευτικη - Google Patents

Παραγωγα ουριας τροπανιου, η παρασκευη τους και οι εφαρμογες τους στη θεραπευτικη

Info

Publication number
CY1110132T1
CY1110132T1 CY20101100571T CY101100571T CY1110132T1 CY 1110132 T1 CY1110132 T1 CY 1110132T1 CY 20101100571 T CY20101100571 T CY 20101100571T CY 101100571 T CY101100571 T CY 101100571T CY 1110132 T1 CY1110132 T1 CY 1110132T1
Authority
CY
Cyprus
Prior art keywords
tropani
therapeutics
urine
products
applications
Prior art date
Application number
CY20101100571T
Other languages
English (en)
Inventor
Michel Aletru
Alain Braun
Claudie Namane
Olivier Venier
Christophe Philippo
Patrick Mougenot
Eric Nicolai
Stefan Gussregen
Original Assignee
Sanofi-Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0605785A external-priority patent/FR2902791B1/fr
Priority claimed from FR0700507A external-priority patent/FR2911874B1/fr
Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis
Publication of CY1110132T1 publication Critical patent/CY1110132T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Η εφεύρεση αφορά τις ενώσεις που αντιστοιχούν στον γενικό τύπο (I) : όπου τα R1a, R1b, R1c, R1d, R2a, R2b, R3, P4, p, r και Χ είναι όπως ορίζονται στην περιγραφή. Διαδικασία παρασκευής και εφαρμογή στη θεραπευτική.
CY20101100571T 2006-06-27 2010-06-21 Παραγωγα ουριας τροπανιου, η παρασκευη τους και οι εφαρμογες τους στη θεραπευτικη CY1110132T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0605785A FR2902791B1 (fr) 2006-06-27 2006-06-27 Derives d'urees de tropane,leur preparation et leur application en therapeutique
FR0700507A FR2911874B1 (fr) 2007-01-25 2007-01-25 Derives d'urees de tropane, leur preparation et leur application en therapeutique
EP07803782A EP2046791B1 (fr) 2006-06-27 2007-06-26 Dérivés d'urees de tropane, leur préparation et leur application en thérapeutique

Publications (1)

Publication Number Publication Date
CY1110132T1 true CY1110132T1 (el) 2015-01-14

Family

ID=38820110

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100571T CY1110132T1 (el) 2006-06-27 2010-06-21 Παραγωγα ουριας τροπανιου, η παρασκευη τους και οι εφαρμογες τους στη θεραπευτικη

Country Status (23)

Country Link
US (2) US7897773B2 (el)
EP (1) EP2046791B1 (el)
JP (1) JP2009541464A (el)
KR (1) KR20090021193A (el)
AR (1) AR061642A1 (el)
AT (1) ATE461930T1 (el)
AU (1) AU2007264792A1 (el)
CA (1) CA2648769A1 (el)
CL (1) CL2007001885A1 (el)
CY (1) CY1110132T1 (el)
DE (1) DE602007005487D1 (el)
DK (1) DK2046791T3 (el)
ES (1) ES2342793T3 (el)
IL (1) IL195510A0 (el)
MX (1) MX277822B (el)
PE (1) PE20080344A1 (el)
PL (1) PL2046791T3 (el)
PT (1) PT2046791E (el)
RU (1) RU2009102535A (el)
SI (1) SI2046791T1 (el)
TW (1) TW200811170A (el)
UY (1) UY30447A1 (el)
WO (1) WO2008000951A2 (el)

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Also Published As

Publication number Publication date
PL2046791T3 (pl) 2010-08-31
KR20090021193A (ko) 2009-02-27
ES2342793T3 (es) 2010-07-14
IL195510A0 (en) 2009-09-01
MX277822B (es) 2010-08-03
EP2046791B1 (fr) 2010-03-24
AU2007264792A1 (en) 2008-01-03
WO2008000951A3 (fr) 2008-02-21
PE20080344A1 (es) 2008-06-09
AR061642A1 (es) 2008-09-10
ATE461930T1 (de) 2010-04-15
WO2008000951A2 (fr) 2008-01-03
US20100324084A1 (en) 2010-12-23
CL2007001885A1 (es) 2008-01-25
TW200811170A (en) 2008-03-01
US7897773B2 (en) 2011-03-01
JP2009541464A (ja) 2009-11-26
MX2008016492A (es) 2009-01-22
DE602007005487D1 (de) 2010-05-06
DK2046791T3 (da) 2010-07-19
UY30447A1 (es) 2008-01-31
EP2046791A2 (fr) 2009-04-15
RU2009102535A (ru) 2010-08-10
CA2648769A1 (fr) 2008-01-03
SI2046791T1 (sl) 2010-07-30
US20090170894A1 (en) 2009-07-02
PT2046791E (pt) 2010-06-23

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