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CY1109307T1 - Χρηση αδαπαλενιου για τη θεραπεια δερματολογικων διαταραχων - Google Patents

Χρηση αδαπαλενιου για τη θεραπεια δερματολογικων διαταραχων

Info

Publication number
CY1109307T1
CY1109307T1 CY20091100860T CY091100860T CY1109307T1 CY 1109307 T1 CY1109307 T1 CY 1109307T1 CY 20091100860 T CY20091100860 T CY 20091100860T CY 091100860 T CY091100860 T CY 091100860T CY 1109307 T1 CY1109307 T1 CY 1109307T1
Authority
CY
Cyprus
Prior art keywords
adapalenium
disorder treatment
dermatological disorder
treatment
dermatological
Prior art date
Application number
CY20091100860T
Other languages
English (en)
Inventor
Michael Graeber
Janusz Czernielewski
Original Assignee
Galderma Research & Development
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27806678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1109307(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR0203070A external-priority patent/FR2837101B1/fr
Application filed by Galderma Research & Development filed Critical Galderma Research & Development
Publication of CY1109307T1 publication Critical patent/CY1109307T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
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    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/362—Polycarboxylic acids
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
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    • A61K9/0012—Galenical forms characterised by the site of application
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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    • A61Q19/008—Preparations for oily skin
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6903—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

Η παρούσα ευρεσιτεχνία αναφέρεται στην χρήση του 6-[3-(1-αδαμαντυλο)-4-μεθοξυ-φαινυλο]-2-ναφθανοϊκού οξέος (αδαπαλενίου), ή των αλάτων αυτού, για την παραγωγή φαρμακευτικής συνθέσεως προοριζόμενης για την θεραπεία δερματολογικών ενοχλήσεων με φλεγμονώδες ή πολλαπλασιαστικό συστατικό, περιλαμβάνουσα 0,3% κ.β. αδαπαλένιο ως προς το ολικό βάρος της συνθέσεως.
CY20091100860T 2002-03-12 2009-08-12 Χρηση αδαπαλενιου για τη θεραπεια δερματολογικων διαταραχων CY1109307T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0203070A FR2837101B1 (fr) 2002-03-12 2002-03-12 Utilisation de l'acide 6-[1-adamantyl)-4-methoxyphenyl]-2- naphthoique pour le traitement de desordres dermatologiques
US37022302P 2002-04-08 2002-04-08
EP03712109A EP1485080B1 (en) 2002-03-12 2003-03-12 Use of adapalene for the treatment of dermatological disorders

Publications (1)

Publication Number Publication Date
CY1109307T1 true CY1109307T1 (el) 2014-07-02

Family

ID=27806678

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20091100266T CY1108868T1 (el) 2002-03-12 2009-03-10 Συνθεση περιλαμβανουσα 6-[3-( 1 -αδαμαντυλο)-4-μεθοξυφαινυλo]-2-ναφθοϊκο οξυ για την θεραπεια δερματολογικων διαταραχων
CY20091100860T CY1109307T1 (el) 2002-03-12 2009-08-12 Χρηση αδαπαλενιου για τη θεραπεια δερματολογικων διαταραχων

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20091100266T CY1108868T1 (el) 2002-03-12 2009-03-10 Συνθεση περιλαμβανουσα 6-[3-( 1 -αδαμαντυλο)-4-μεθοξυφαινυλo]-2-ναφθοϊκο οξυ για την θεραπεια δερματολογικων διαταραχων

Country Status (19)

Country Link
US (17) US7579377B2 (el)
EP (2) EP1532974B1 (el)
JP (2) JP2005526063A (el)
CN (1) CN1642538B (el)
AT (2) ATE432072T1 (el)
AU (2) AU2003216898B2 (el)
BR (1) BRPI0307550B8 (el)
CA (1) CA2478237C (el)
CY (2) CY1108868T1 (el)
DE (2) DE60327745D1 (el)
DK (2) DK1485080T3 (el)
ES (2) ES2327508T3 (el)
HK (1) HK1073996A1 (el)
MX (1) MXPA04008684A (el)
PL (1) PL216763B1 (el)
PT (2) PT1532974E (el)
RU (2) RU2332208C2 (el)
SI (2) SI1485080T1 (el)
WO (1) WO2003075908A1 (el)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820186B2 (en) 2001-12-21 2010-10-26 Galderma Research & Development Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt
WO2003075908A1 (en) * 2002-03-12 2003-09-18 Galderma Research & Development, S.N.C. Use of adapalene for the treatment of dermatological disorders
US20080161273A1 (en) * 2004-10-20 2008-07-03 Galderma Research & Development Method of Using Adapalene in Acne Maintenance Therapy
US20060128808A1 (en) * 2004-10-20 2006-06-15 Galderma Research & Development, S.N.C. Method of using adapalene in acne maintenance therapy
KR20070091613A (ko) * 2004-11-08 2007-09-11 그렌마크 파머수티칼스 엘티디. 항여드름 화합물 및 항생제 화합물을 함유하는 국소적 제약조성물
FR2879459B1 (fr) * 2004-12-22 2007-02-16 Galderma Res & Dev Composition comprenant de l'adapalene solubilise avec des cyclodextrines
CA2591062A1 (en) 2005-01-26 2006-08-03 Galderma Research & Development Adapalene for the long-term treatment of acne vulgaris
ITRM20050248A1 (it) * 2005-05-20 2006-11-21 Sigma Tau Ind Farmaceuti Uso acido adamantil metossidifenil propenoico per il trattamento di patologie cutanee.
US8119834B2 (en) 2005-06-17 2012-02-21 Medichem, S.A. Process for the preparation of adapalene and related compounds
FR2890861B1 (fr) 2005-09-16 2010-05-28 Galderma Res & Dev Compositions comprenant au moins un derive de l'acide naphtoique et au moins un compose de type polymeres de polyurethanes ou des derives de celui-ci, leurs procede de preparation, et leur utilisation
MX2008003422A (es) * 2005-09-16 2008-03-27 Galderma Res & Dev Composiciones que comprenden al menos un derivado de acido naftoico y al menos un compuesto de tipo polimero de poliuretano o derivados del mismo, procesos de preparacion y composiciones que comprenden al menos un derivado de acido naftoico y al meno
FR2894821B1 (fr) * 2005-12-15 2008-02-29 Galderma Res & Dev Compositions comprenant au moins un compose retinoide et au moins un compose anti-irritant et leurs utilisations
CN1989956B (zh) * 2005-12-29 2010-09-01 北京德众万全医药科技有限公司 一种阿达帕林凝胶组合物及其制备方法
FR2901701B1 (fr) * 2006-05-31 2010-10-29 Galderma Res & Dev Compostions comprenant au moins un derive de l'acide naphtoique et au moins un agent filmogene, leurs procedes de preparation, et leurs utilisations
EP2097076A1 (fr) * 2006-11-20 2009-09-09 Galderma Research & Development, S.N.C. Utilisation d'adapalène pour moduler l'expression de l'il-1ra.
FR2909000B1 (fr) * 2006-11-28 2009-02-06 Galderma Res & Dev S N C Snc Compositions comprenant du peroxyde de benzoyle, au moins un derive de l'acide naphtoique et au moins un compose de type polymeres de polyurethane ou des derives de celui-ci, et leurs utilisations.
NZ597056A (en) * 2006-12-15 2012-12-21 Colgate Palmolive Co Liquid hand dish detergent having suspended particulate material
FR2910321B1 (fr) 2006-12-21 2009-07-10 Galderma Res & Dev S N C Snc Gel creme comprenant au moins un retinoide et du peroxyde de benzole
FR2910320B1 (fr) 2006-12-21 2009-02-13 Galderma Res & Dev S N C Snc Emulsion comprenant au moins un retinoide et du peroxyde de benzole
JP5338030B2 (ja) * 2007-01-31 2013-11-13 大正製薬株式会社 アダパレン含有外用剤組成物
JP5670008B2 (ja) * 2007-01-31 2015-02-18 大正製薬株式会社 アダパレン含有外用剤組成物
JP5125122B2 (ja) * 2007-01-31 2013-01-23 大正製薬株式会社 アダパレン含有外用剤組成物
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