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CY1109055T1 - 11-((4r,6r)-4,5,6-τριϋδροξυ-3-(r)-υδροξυ-εξυλοκαρβαμοϋλο)-ενδεκαϊνικο οξυ - Google Patents

11-((4r,6r)-4,5,6-τριϋδροξυ-3-(r)-υδροξυ-εξυλοκαρβαμοϋλο)-ενδεκαϊνικο οξυ

Info

Publication number
CY1109055T1
CY1109055T1 CY20091100503T CY091100503T CY1109055T1 CY 1109055 T1 CY1109055 T1 CY 1109055T1 CY 20091100503 T CY20091100503 T CY 20091100503T CY 091100503 T CY091100503 T CY 091100503T CY 1109055 T1 CY1109055 T1 CY 1109055T1
Authority
CY
Cyprus
Prior art keywords
triphyroxy
indecaic
hexylcarbamoyl
hydroxy
acid
Prior art date
Application number
CY20091100503T
Other languages
English (en)
Inventor
Gerhard Dr Jaehne
Wendelin Dr Frick
Andreas Dr Lindenschmidt
Stefanie Dr Flohr
Hubert Dr Heuer
Hans-Ludwig Schaefer
Werner Prof Dr Kramer
Eric Dr Galia
Heiner Dr Glombik
Original Assignee
Sanofi-Aventis Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis Deutschland Gmbh filed Critical Sanofi-Aventis Deutschland Gmbh
Publication of CY1109055T1 publication Critical patent/CY1109055T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Η εφεύρεση αφορά στο γινόμενο παράγωγο του τύπου
CY20091100503T 2003-04-01 2009-05-11 11-((4r,6r)-4,5,6-τριϋδροξυ-3-(r)-υδροξυ-εξυλοκαρβαμοϋλο)-ενδεκαϊνικο οξυ CY1109055T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10314610A DE10314610A1 (de) 2003-04-01 2003-04-01 Neues Diphenylazetidinon mit verbesserten physiologischen Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindungen enthaltende Arzneimittel und dessen Verwendung
EP07016889A EP1862455B1 (de) 2003-04-01 2004-03-16 11-((4R,6R)-4,5,6-Trihydroxy-3-(R)-hydroxy-2-(S)-hydroxy-hexylcarbamoyl)-Undekansäure

Publications (1)

Publication Number Publication Date
CY1109055T1 true CY1109055T1 (el) 2014-07-02

Family

ID=33103147

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20081100429T CY1107398T1 (el) 2003-04-01 2008-04-17 Νεα διφαινυλαζητιδoνη με βελτιωμενες φυσιολογικες ιδιοτητες, η διαδικασια για την παραγωγη της, το φαρμακευτικο παρασκευασμα που περιεχει τις ενωσεις αυτες καθως και η χρηση του
CY20091100503T CY1109055T1 (el) 2003-04-01 2009-05-11 11-((4r,6r)-4,5,6-τριϋδροξυ-3-(r)-υδροξυ-εξυλοκαρβαμοϋλο)-ενδεκαϊνικο οξυ

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20081100429T CY1107398T1 (el) 2003-04-01 2008-04-17 Νεα διφαινυλαζητιδoνη με βελτιωμενες φυσιολογικες ιδιοτητες, η διαδικασια για την παραγωγη της, το φαρμακευτικο παρασκευασμα που περιεχει τις ενωσεις αυτες καθως και η χρηση του

Country Status (43)

Country Link
US (2) US7205290B2 (el)
EP (2) EP1862455B1 (el)
JP (1) JP2006522040A (el)
KR (1) KR20050119180A (el)
CN (2) CN101139306A (el)
AR (1) AR043783A1 (el)
AT (2) ATE423766T1 (el)
AU (1) AU2004226287B2 (el)
BR (1) BRPI0408920A (el)
CA (1) CA2520689A1 (el)
CL (1) CL43489B (el)
CR (1) CR7995A (el)
CY (2) CY1107398T1 (el)
DE (3) DE10314610A1 (el)
DK (2) DK1613589T3 (el)
EC (1) ECSP056071A (el)
ES (2) ES2322876T3 (el)
GT (1) GT200400058A (el)
HN (1) HN2004000109A (el)
HR (1) HRP20050870A2 (el)
JO (1) JO2493B1 (el)
MA (1) MA27753A1 (el)
ME (1) MEP41408A (el)
MX (1) MXPA05010128A (el)
MY (1) MY136269A (el)
NI (1) NI200500164A (el)
NO (1) NO20055001L (el)
NZ (1) NZ542751A (el)
PA (1) PA8599401A1 (el)
PE (1) PE20050011A1 (el)
PL (2) PL1862455T3 (el)
PT (2) PT1613589E (el)
RS (1) RS51146B (el)
RU (1) RU2334737C2 (el)
SA (1) SA04250154B1 (el)
SI (2) SI1862455T1 (el)
SV (1) SV2004001756A (el)
TN (1) TNSN05244A1 (el)
TW (1) TW200504009A (el)
UA (1) UA80754C2 (el)
UY (1) UY28253A1 (el)
WO (1) WO2004087655A1 (el)
ZA (1) ZA200506708B (el)

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US8809325B2 (en) 2011-03-08 2014-08-19 Sanofi Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120053A1 (de) 2011-03-08 2012-09-13 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8846666B2 (en) 2011-03-08 2014-09-30 Sanofi Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8901114B2 (en) 2011-03-08 2014-12-02 Sanofi Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
EP2683700B1 (de) 2011-03-08 2015-02-18 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
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Also Published As

Publication number Publication date
PT1862455E (pt) 2009-04-23
DK1613589T3 (da) 2008-06-09
NZ542751A (en) 2007-05-31
PA8599401A1 (es) 2004-10-08
DE502004009059D1 (de) 2009-04-09
PT1613589E (pt) 2008-03-27
DE10314610A1 (de) 2004-11-04
ES2298731T3 (es) 2008-05-16
HK1087697A1 (zh) 2006-10-20
UA80754C2 (en) 2007-10-25
ES2322876T3 (es) 2009-06-30
NO20055001L (no) 2005-10-27
AU2004226287B2 (en) 2010-03-18
PL1613589T3 (pl) 2008-07-31
ZA200506708B (en) 2007-01-31
EP1862455A2 (de) 2007-12-05
US7205290B2 (en) 2007-04-17
PE20050011A1 (es) 2005-02-28
US20070197498A1 (en) 2007-08-23
CA2520689A1 (en) 2004-10-14
GT200400058A (es) 2004-11-10
JO2493B1 (en) 2009-10-05
EP1862455A3 (de) 2007-12-12
DE502004006195D1 (de) 2008-03-27
AR043783A1 (es) 2005-08-10
WO2004087655A1 (de) 2004-10-14
CN100361970C (zh) 2008-01-16
US7772429B2 (en) 2010-08-10
EP1613589A1 (de) 2006-01-11
PL1862455T3 (pl) 2009-07-31
CN1768034A (zh) 2006-05-03
SI1862455T1 (sl) 2009-06-30
SA04250154B1 (ar) 2007-10-29
CL43489B (es) 2005-01-21
BRPI0408920A (pt) 2006-03-28
MY136269A (en) 2008-09-30
CY1107398T1 (el) 2012-12-19
KR20050119180A (ko) 2005-12-20
RU2005133631A (ru) 2006-03-10
MA27753A1 (fr) 2006-02-01
SI1613589T1 (sl) 2008-06-30
HRP20050870A2 (en) 2006-10-31
EP1862455B1 (de) 2009-02-25
US20050020563A1 (en) 2005-01-27
MEP41408A (en) 2011-02-10
SV2004001756A (es) 2004-11-18
MXPA05010128A (es) 2005-11-16
CR7995A (es) 2006-09-22
AU2004226287A1 (en) 2004-10-14
DK1862455T3 (da) 2009-06-02
NI200500164A (es) 2006-01-11
HN2004000109A (es) 2008-02-21
ECSP056071A (es) 2006-01-27
RS20050719A (en) 2008-04-04
EP1613589B1 (de) 2008-02-13
CN101139306A (zh) 2008-03-12
TW200504009A (en) 2005-02-01
RU2334737C2 (ru) 2008-09-27
ATE386020T1 (de) 2008-03-15
ATE423766T1 (de) 2009-03-15
TNSN05244A1 (en) 2007-06-11
UY28253A1 (es) 2004-11-08
RS51146B (sr) 2010-10-31
JP2006522040A (ja) 2006-09-28

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