CY1108013T1 - Dna εμβολια για τους ιππους που περιεχουν ανοσοενισχυτικους παραγοντες με πολυμερη του ακρυλικου ή μεθακρυλικου οξεος ή του εμα(r) - Google Patents
Dna εμβολια για τους ιππους που περιεχουν ανοσοενισχυτικους παραγοντες με πολυμερη του ακρυλικου ή μεθακρυλικου οξεος ή του εμα(r)Info
- Publication number
- CY1108013T1 CY1108013T1 CY20071100615T CY071100615T CY1108013T1 CY 1108013 T1 CY1108013 T1 CY 1108013T1 CY 20071100615 T CY20071100615 T CY 20071100615T CY 071100615 T CY071100615 T CY 071100615T CY 1108013 T1 CY1108013 T1 CY 1108013T1
- Authority
- CY
- Cyprus
- Prior art keywords
- ema
- methacrylic acid
- immunosuppressive agents
- dna vaccines
- polymeric acrylic
- Prior art date
Links
- 108010041986 DNA Vaccines Proteins 0.000 title abstract 2
- 229940021995 DNA vaccine Drugs 0.000 title abstract 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 title 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 title 1
- 229940125721 immunosuppressive agent Drugs 0.000 title 1
- 239000003018 immunosuppressive agent Substances 0.000 title 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical group OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- 108091061960 Naked DNA Proteins 0.000 abstract 1
- 229920002125 Sokalan® Polymers 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 229960001631 carbomer Drugs 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
To DNA εμβόλιο περιέχει ένα γυμνό DNA που ενσωματώνει και εκφράζει in vivo μια νουκλεοτιδική αλληλουχία που κωδικοποιεί ένα αντιγονικό πολυπεπτίδιο, κατά προτίμηση ένα γονίδιο ενός παθογόνου παράγοντα, και τουλάχιστον μια ανοσοενισχυτική ένωση που επιλέγεται μεταξύ των ακρυλικών ή μεθακρυλικών πολυμερών και των συμπολυμερών του μηλεϊνικού ανυδρίτη και του παραγώγου του αλκενυλίου. Η ανοσοενισχυτική ένωση είναι κατά προτίμηση ένα καρβομερές ή ένα ΕΜΑ®.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9804409A FR2776928B1 (fr) | 1998-04-03 | 1998-04-03 | Vaccins adn adjuves |
EP99909069A EP1066055B1 (fr) | 1998-04-03 | 1999-03-22 | Vaccins à ADN adjuvés avec des polymères d'acide acrylique ou méthacrylique ou d' EMA (R) pour les chevaux |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1108013T1 true CY1108013T1 (el) | 2013-09-04 |
Family
ID=9525029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20071100615T CY1108013T1 (el) | 1998-04-03 | 2007-05-09 | Dna εμβολια για τους ιππους που περιεχουν ανοσοενισχυτικους παραγοντες με πολυμερη του ακρυλικου ή μεθακρυλικου οξεος ή του εμα(r) |
Country Status (17)
Country | Link |
---|---|
US (1) | US7163926B1 (el) |
EP (1) | EP1066055B1 (el) |
JP (1) | JP2002510651A (el) |
AR (1) | AR037062A1 (el) |
AT (1) | ATE353670T1 (el) |
AU (1) | AU744964B2 (el) |
BR (1) | BR9909342A (el) |
CA (1) | CA2327389C (el) |
CY (1) | CY1108013T1 (el) |
DE (1) | DE69935136T2 (el) |
DK (1) | DK1066055T3 (el) |
ES (1) | ES2283105T3 (el) |
FR (1) | FR2776928B1 (el) |
PL (1) | PL194348B1 (el) |
PT (1) | PT1066055E (el) |
WO (1) | WO1999051269A1 (el) |
ZA (1) | ZA992478B (el) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2804026B1 (fr) * | 2000-01-21 | 2004-06-11 | Merial Sas | Vaccination contre l'herpesvirose canine et vaccins |
US6551598B2 (en) | 2000-01-21 | 2003-04-22 | Merial | Vaccination against canine herpesvirosis and vaccines therefor |
JP2005513062A (ja) * | 2001-12-14 | 2005-05-12 | ジェネトロニクス インコーポレイテッド | パルス電場を使用した粒子支援ポリヌクレオチド免疫方法 |
US7959929B2 (en) | 2005-04-21 | 2011-06-14 | University Of Florida Research Foundation, Inc. | Materials and methods for respiratory disease control in canines |
US11865172B2 (en) | 2005-04-21 | 2024-01-09 | University Of Florida Research Foundation, Inc. | Materials and methods for respiratory disease control in canines |
US7682619B2 (en) | 2006-04-06 | 2010-03-23 | Cornell Research Foundation, Inc. | Canine influenza virus |
UA100370C2 (uk) | 2006-12-11 | 2012-12-25 | Мериал Лимитед | Спосіб вакцинації птахів проти salmonella |
CL2008001806A1 (es) | 2007-06-20 | 2008-09-05 | Wyeth Corp | Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion. |
GB0805356D0 (en) * | 2008-03-25 | 2008-04-30 | Isis Innovation | Vaccine adjuvant composition |
EP2283035B1 (en) | 2008-05-08 | 2015-07-29 | Merial Limited | Leishmania vaccine using sand fly salivary immunogen |
AP3334A (en) * | 2008-10-24 | 2015-07-31 | Univ California | Vaccine against african horse sickness virus |
BR112014001287B1 (pt) | 2011-07-20 | 2020-12-08 | Centre National De La Recherche Scientifique | vacina recombinante do vírus da leucemia felina contendo gene otimizado do envelope do vírus da leucemia felina |
WO2013106558A1 (en) | 2012-01-10 | 2013-07-18 | Merial Limited | Lipid based adjuvants for dna - plasmid vaccines |
BR112014023414B1 (pt) | 2012-03-20 | 2022-08-30 | Boehringer Ingelheim Animal Health USA Inc. | Vacina de herpesvirus-1 equino recombinante contendo uma glicoproteína c mutante e seus usos |
JP6405308B2 (ja) | 2012-08-30 | 2018-10-17 | メリアル インコーポレイテッド | キメラksacタンパク質の発現及び高圧により可溶性タンパク質を製造する方法 |
WO2016210097A1 (en) * | 2015-06-23 | 2016-12-29 | The Trustees Of Columbia University In The City Of New York | Novel equine parvovirus and uses thereof |
WO2017218819A1 (en) | 2016-06-17 | 2017-12-21 | Merial, Inc. | Novel immunogenic formulations comprising linear or branched polyacrylic acid polymer adjuvants |
EP4178937A4 (en) * | 2020-07-07 | 2024-10-30 | Amyris, Inc. | VACCINE ADJUVANTS AND PROCESSES FOR THEIR SYNTHESIS AND USE |
CN114272368A (zh) * | 2021-12-16 | 2022-04-05 | 成都博宠生物科技有限公司 | 一种猪瘟和猪伪狂犬二联疫苗及其制备方法和应用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3920811A (en) * | 1972-12-22 | 1975-11-18 | Cutter Lab | Adjuvant compositions |
JPH0832637B2 (ja) * | 1985-02-14 | 1996-03-29 | アクゾ・エヌ・ヴエー | 合成免疫原 |
ES2052685T3 (es) * | 1987-03-17 | 1994-07-16 | Akzo Nv | Metodo para producir un adyuvante libre. |
US6004563A (en) * | 1990-11-07 | 1999-12-21 | American Home Products Corporation | Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same |
EP0532833A1 (en) * | 1991-05-28 | 1993-03-24 | Miles Inc. | Vaccine for equine rhinopneumonitis |
WO1993024528A1 (en) * | 1992-06-01 | 1993-12-09 | The University Of Melbourne | Equine herpesvirus glycoproteins |
AU5543294A (en) * | 1993-10-29 | 1995-05-22 | Pharmos Corp. | Submicron emulsions as vaccine adjuvants |
BE1008977A5 (fr) * | 1994-12-27 | 1996-10-01 | Solvay | Adjuvants pour vaccins. |
US6300118B1 (en) * | 1995-06-07 | 2001-10-09 | American Home Products Corporation | Plasmids comprising a genetically altered feline immunodeficiency virus genome |
US5820869A (en) * | 1995-06-07 | 1998-10-13 | American Home Products Corporation | Recombinant raccoon pox viruses and their use as an effective vaccine against feline immunodeficiency virus infection |
FR2751226B1 (fr) * | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies du cheval |
GB9623051D0 (en) * | 1996-11-06 | 1997-01-08 | Schacht Etienne H | Delivery of DNA to target cells in biological systems |
US6406705B1 (en) * | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
US6261568B1 (en) * | 1997-06-11 | 2001-07-17 | Institut Pasteur | Attenuated recombinant mycobacteria useful as immunogens or as vaccine components |
AU8392898A (en) * | 1997-07-14 | 1999-02-10 | Powerject Vaccines, Inc. | Method of dna vaccination using dna encoding antigen and encoding il6 |
GB9726398D0 (en) * | 1997-12-12 | 1998-02-11 | Isis Innovation | Polypeptide and coding sequences |
US6444799B1 (en) * | 1997-12-31 | 2002-09-03 | Csl Limited | P. gingivalis polynucleotides and uses thereof |
-
1998
- 1998-04-03 FR FR9804409A patent/FR2776928B1/fr not_active Expired - Lifetime
-
1999
- 1999-03-22 CA CA2327389A patent/CA2327389C/en not_active Expired - Lifetime
- 1999-03-22 EP EP99909069A patent/EP1066055B1/fr not_active Expired - Lifetime
- 1999-03-22 BR BR9909342-1A patent/BR9909342A/pt not_active Application Discontinuation
- 1999-03-22 AU AU28448/99A patent/AU744964B2/en not_active Expired
- 1999-03-22 DE DE69935136T patent/DE69935136T2/de not_active Expired - Lifetime
- 1999-03-22 ES ES99909069T patent/ES2283105T3/es not_active Expired - Lifetime
- 1999-03-22 JP JP2000542039A patent/JP2002510651A/ja active Pending
- 1999-03-22 PL PL99343602A patent/PL194348B1/pl unknown
- 1999-03-22 AT AT99909069T patent/ATE353670T1/de active
- 1999-03-22 DK DK99909069T patent/DK1066055T3/da active
- 1999-03-22 WO PCT/FR1999/000666 patent/WO1999051269A1/fr active IP Right Grant
- 1999-03-22 PT PT99909069T patent/PT1066055E/pt unknown
- 1999-03-31 ZA ZA9902478A patent/ZA992478B/xx unknown
- 1999-03-31 AR ARP990101458A patent/AR037062A1/es unknown
-
2000
- 2000-10-02 US US09/677,672 patent/US7163926B1/en not_active Expired - Lifetime
-
2007
- 2007-05-09 CY CY20071100615T patent/CY1108013T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
AR037062A1 (es) | 2004-10-20 |
WO1999051269A1 (fr) | 1999-10-14 |
EP1066055A1 (fr) | 2001-01-10 |
FR2776928A1 (fr) | 1999-10-08 |
AU744964B2 (en) | 2002-03-07 |
AU2844899A (en) | 1999-10-25 |
PL343602A1 (en) | 2001-08-27 |
PT1066055E (pt) | 2007-05-31 |
ES2283105T3 (es) | 2007-10-16 |
EP1066055B1 (fr) | 2007-02-14 |
US7163926B1 (en) | 2007-01-16 |
FR2776928B1 (fr) | 2000-06-23 |
CA2327389C (en) | 2011-06-14 |
DE69935136T2 (de) | 2007-11-29 |
ZA992478B (en) | 2000-10-10 |
DE69935136D1 (de) | 2007-03-29 |
JP2002510651A (ja) | 2002-04-09 |
ATE353670T1 (de) | 2007-03-15 |
PL194348B1 (pl) | 2007-05-31 |
DK1066055T3 (da) | 2007-06-11 |
CA2327389A1 (en) | 1999-10-14 |
BR9909342A (pt) | 2000-12-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1108013T1 (el) | Dna εμβολια για τους ιππους που περιεχουν ανοσοενισχυτικους παραγοντες με πολυμερη του ακρυλικου ή μεθακρυλικου οξεος ή του εμα(r) | |
DK0886644T3 (da) | Lang bölgelængde-modificerede fluorescerende proteiner | |
MX9400837A (es) | Metodos y aparatos para la determinacion de secuencia de adn. | |
ATE334216T1 (de) | Impstoff gegen felines immunodefizienz-virus | |
CY1116385T1 (el) | Αντινοηματικη διαμορφωση της εκφρασης της απολιποπρωτεινης β | |
BG101103A (bg) | Теломераза при бозайници | |
DE69734882D1 (de) | Dna immunisierung gegen chlamydia infektion | |
ATE411001T1 (de) | Immunmodulations-vorrichtung zur verwendung in tieren | |
ATE335831T1 (de) | Nukleinsäurevektor, einen solchen vektor enthaltene verbindung und impfstoff zur immunisierung gegen hepatitis | |
HRP20070012A2 (hr) | Imunostimulatorski oligonukleotidni multimeri | |
FR2741806B1 (fr) | Vaccin vivant recombinant a base d'herpesvirus felin de type 1, notamment contre la peritonite infectieuse feline | |
NO990025D0 (no) | Hamster-EF-1<alfa> transkripsjonsregulatorisk DNA | |
CY1105439T1 (el) | Κυτταρα, μεθοδοι καλλιεργειας και η χρηση τους στη θepαπεια με αυτολογη μεταμοσχευση | |
DE69836092D1 (de) | Rekombinatorisches klonieren unter verwendung von nukleinsaüren mit rekombinationsstellen | |
BR0114199A (pt) | Sequências de nucleotìdeos que medeiam a fertilidade masculina e métodos de uso das mesmas | |
BR9811039A (pt) | Citocina de mamìferos: interleucina-b30 e reagentes relacionados | |
ES2143507T3 (es) | Vacunas contra la enfermedad de aujeszky y de otras enfermedades animales que contienen mutantes del virus de la pseudorrabia. | |
DK1227837T3 (da) | Fremgangsmåde til introduktion og/eller fremskyndelse af et immunrespons på et tumorantigen | |
CY1116774T1 (el) | Συνθεση η οποια περιεχει lip2a leishmania | |
ATE439441T1 (de) | Veränderte, fluoreszierende proteine | |
DE60114804D1 (de) | Konstruierte fluoreszenzproteine mit langen wellenlängen | |
ES2083629T3 (es) | Inmovilizacion de acidos nucleicos. | |
AR009365A1 (es) | Vacunas del virus de la fiebre aftosa (fmdv), peptidos, secuencias de adn y el uso de los peptidos en sistemas de deteccion y el uso de la vacuna fmdc para la preparacion de una composicion para inmunizar cerdos y ganado vacuno | |
DE60000939D1 (de) | Wasserdispergierbare polyamide mit ethylenisch ungesättigten endgruppen | |
UY26266A1 (es) | Antigeno asociado con tumores (r11) ley 17164 |