CY1106468T1 - Υποκατεστημενα παραγωγα κυκλοεξανο-1,4-διαμινης - Google Patents
Υποκατεστημενα παραγωγα κυκλοεξανο-1,4-διαμινηςInfo
- Publication number
- CY1106468T1 CY1106468T1 CY20071100630T CY071100630T CY1106468T1 CY 1106468 T1 CY1106468 T1 CY 1106468T1 CY 20071100630 T CY20071100630 T CY 20071100630T CY 071100630 T CY071100630 T CY 071100630T CY 1106468 T1 CY1106468 T1 CY 1106468T1
- Authority
- CY
- Cyprus
- Prior art keywords
- substituted cyclohexane
- diamine derivatives
- preparation
- diamine
- cyclohexane
- Prior art date
Links
- VKIRRGRTJUUZHS-UHFFFAOYSA-N cyclohexane-1,4-diamine Chemical class NC1CCC(N)CC1 VKIRRGRTJUUZHS-UHFFFAOYSA-N 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
- C07C211/36—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing at least two amino groups bound to the carbon skeleton
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/132—Amines having two or more amino groups, e.g. spermidine, putrescine
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- A—HUMAN NECESSITIES
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- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Nutrition Science (AREA)
- Dermatology (AREA)
- Child & Adolescent Psychology (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
Abstract
Η εφεύρεση αφορά υποκατεστημένα παράγωγα κυκλοεξανο-1,4-διαμίνης, μεθόδους για την παρασκευή τους, φάρμακα που περιέχουν τις ενώσεις αυτές και τη χρησιμοποίηση υποκατεστημένων παραγώγων κυκλοεξανο-1,4-διαμίνης για την παρασκευή φαρμάκων.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10123163A DE10123163A1 (de) | 2001-05-09 | 2001-05-09 | Substituierte Cyclohexan-1,4-diaminderivate |
| PCT/EP2002/005051 WO2002090317A1 (de) | 2001-05-09 | 2002-05-08 | Substituierte cyclohexan-1,4-diaminderivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1106468T1 true CY1106468T1 (el) | 2012-01-25 |
Family
ID=7684562
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20071100630T CY1106468T1 (el) | 2001-05-09 | 2007-05-10 | Υποκατεστημενα παραγωγα κυκλοεξανο-1,4-διαμινης |
| CY20071101374T CY1108067T1 (el) | 2001-05-09 | 2007-10-25 | Υποκατεστημενα παραγωγα 2-πυριδινο-κυκλοεξανο-1,4-διαμινης |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20071101374T CY1108067T1 (el) | 2001-05-09 | 2007-10-25 | Υποκατεστημενα παραγωγα 2-πυριδινο-κυκλοεξανο-1,4-διαμινης |
Country Status (31)
| Country | Link |
|---|---|
| US (3) | US7276518B2 (el) |
| EP (3) | EP1385825B1 (el) |
| JP (3) | JP2004533439A (el) |
| KR (2) | KR100895778B1 (el) |
| CN (2) | CN1533374B (el) |
| AR (1) | AR035883A1 (el) |
| AT (2) | ATE370120T1 (el) |
| AU (3) | AU2002341195B2 (el) |
| BR (2) | BR0209579A (el) |
| CA (3) | CA2446463C (el) |
| CO (2) | CO5540300A2 (el) |
| CY (2) | CY1106468T1 (el) |
| CZ (2) | CZ20033005A3 (el) |
| DE (3) | DE10123163A1 (el) |
| DK (2) | DK1392641T3 (el) |
| EC (2) | ECSP034830A (el) |
| ES (2) | ES2284876T3 (el) |
| HK (2) | HK1062911A1 (el) |
| HU (3) | HU229288B1 (el) |
| IL (4) | IL158784A0 (el) |
| MX (3) | MXPA03010134A (el) |
| NO (2) | NO326784B1 (el) |
| NZ (2) | NZ529334A (el) |
| PE (1) | PE20021094A1 (el) |
| PL (3) | PL220595B1 (el) |
| PT (2) | PT1385825E (el) |
| RU (2) | RU2287523C2 (el) |
| SI (2) | SI1385825T1 (el) |
| SK (2) | SK287319B6 (el) |
| WO (3) | WO2002090330A1 (el) |
| ZA (2) | ZA200309521B (el) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10252650A1 (de) * | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Cyclohexyl-Harnstoff-Derivate |
| DE10252665A1 (de) | 2002-11-11 | 2004-06-03 | Grünenthal GmbH | 4-Aminomethyl-1-aryl-cyclohexylamin-Derivate |
| EP1560807B1 (de) | 2002-11-12 | 2010-02-10 | Grünenthal GmbH | 4-hydroxymethyl-1-aryl-cyclohexylamin-derivative |
| EP1562895A1 (en) | 2002-11-19 | 2005-08-17 | Achillion Pharmaceuticals, Inc. | Substituted aryl acylthioureas and related compounds; inhibitors of viral replication |
| US7378409B2 (en) | 2003-08-21 | 2008-05-27 | Bristol-Myers Squibb Company | Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity |
| DE10360792A1 (de) * | 2003-12-23 | 2005-07-28 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| DE10360793A1 (de) * | 2003-12-23 | 2005-07-28 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| DE102004023507A1 (de) | 2004-05-10 | 2005-12-01 | Grünenthal GmbH | Substituierte Cyclohexylessigsäure-Derivate |
| DE102004023501A1 (de) | 2004-05-10 | 2005-12-01 | Grünenthal GmbH | Oxosubstituierte Cyclohexyl-1,4-diamin-Derivate |
| DE102004023635A1 (de) | 2004-05-10 | 2006-04-13 | Grünenthal GmbH | Heteroarylsubstituierte Cyclohexyl-1,4-diamin-Derivate |
| DE102004023508A1 (de) * | 2004-05-10 | 2005-12-08 | Grünenthal GmbH | Säurederivate substituierter Cyclohexyl-1,4-diamine |
| DE102004023632A1 (de) | 2004-05-10 | 2005-12-08 | Grünenthal GmbH | Substituierte Cyclohexylcarbonsäure-Derivate |
| DE102004023506A1 (de) | 2004-05-10 | 2005-12-01 | Grünenthal GmbH | Kettenverlängerte substituierte Cyclohexyl-1,4-diamin-Derivate |
| DE102004023522A1 (de) * | 2004-05-10 | 2005-12-01 | Grünenthal GmbH | Substituierte Cyclohexyl-1,4-diamin-Derivate |
| TW200600492A (en) * | 2004-05-18 | 2006-01-01 | Achillion Pharmaceuticals Inc | Substituted aryl acylthioureas and related compounds; inhibitors of viral replication |
| DE102005061428A1 (de) * | 2005-12-22 | 2007-08-16 | Grünenthal GmbH | Substituierte Cyclohexylmethyl-Derivate |
| DE102006033109A1 (de) * | 2006-07-18 | 2008-01-31 | Grünenthal GmbH | Substituierte Heteroaryl-Derivate |
| DE102006033114A1 (de) | 2006-07-18 | 2008-01-24 | Grünenthal GmbH | Spirocyclische Azaindol-Derivate |
| DE102006035787A1 (de) | 2006-07-28 | 2008-03-13 | Tesa Ag | Verfahren zum Stanzen von bei Raumtemperatur nicht tackigen hitzeaktivierbaren Klebmassen |
| US20080194557A1 (en) * | 2007-01-18 | 2008-08-14 | Joseph Barbosa | Methods and compositions for the treatment of pain, inflammation and cancer |
| CA2692004C (en) * | 2007-06-15 | 2013-04-09 | Board Of Regents, The University Of Texas System | Methods and compositions to inhibit edema factor and adenylyl cyclase |
| US20090215725A1 (en) * | 2008-02-26 | 2009-08-27 | Grunenthal Gmbh | Substituted 4-aminocyclohexane derivatives |
| AU2009228645B2 (en) | 2008-03-27 | 2013-07-18 | Grunenthal Gmbh | Hydroxymethylcyclohexyl amines |
| AR071068A1 (es) | 2008-03-27 | 2010-05-26 | Gruenenthal Chemie | Derivados de ciclohexano espirociclicos sustituidos |
| CN102083790B (zh) | 2008-03-27 | 2014-03-05 | 格吕伦塔尔有限公司 | 螺(5.5)十一烷衍生物 |
| EP2260022B1 (de) | 2008-03-27 | 2017-01-04 | Grünenthal GmbH | Substituierte cyclohexyldiamine |
| ES2544488T3 (es) | 2008-03-27 | 2015-08-31 | Grünenthal GmbH | Derivados de (hetero)aril-ciclohexano |
| AU2009228642B2 (en) * | 2008-03-27 | 2013-11-07 | Grunenthal Gmbh | Substituted 4-aminocyclohexane derivatives |
| PL2324013T6 (pl) | 2008-07-21 | 2015-11-30 | Purdue Pharma Lp | Zmostkowane związki piperydyny typu podstawionej chinoksaliny oraz ich zastosowania |
| WO2010084160A1 (en) | 2009-01-21 | 2010-07-29 | Oryzon Genomics S.A. | Phenylcyclopropylamine derivatives and their medical use |
| AU2010297557C1 (en) | 2009-09-25 | 2017-04-06 | Oryzon Genomics S.A. | Lysine specific demethylase-1 inhibitors and their use |
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