CU20120074A7 - DERIVATIVES OF CARBAMOIL-METHYL-AMINO-ACETIC ACID REPLACED AS NOVEDOUS NEP INHIBITORS - Google Patents
DERIVATIVES OF CARBAMOIL-METHYL-AMINO-ACETIC ACID REPLACED AS NOVEDOUS NEP INHIBITORSInfo
- Publication number
- CU20120074A7 CU20120074A7 CU2012000074A CU20120074A CU20120074A7 CU 20120074 A7 CU20120074 A7 CU 20120074A7 CU 2012000074 A CU2012000074 A CU 2012000074A CU 20120074 A CU20120074 A CU 20120074A CU 20120074 A7 CU20120074 A7 CU 20120074A7
- Authority
- CU
- Cuba
- Prior art keywords
- novedous
- carbamoil
- derivatives
- amino
- methyl
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención proporciona un compuesto de la fórmula I: o una sal farmacéuticamente aceptable del mismo, en donde R1, R2, R3, R4, R6, A1, A2, X1, s y m se definen en la presente. La invención también se refiere a un método para la elaboración de los compuestos de la invención, y a sus usos terapéuticos. La presente invención proporciona además una combinación de agentes farmacológicamente activos y una composición farmacéutica.The present invention provides a compound of the formula I: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R6, A1, A2, X1, s and m are defined herein. The invention also relates to a method for the preparation of the compounds of the invention, and to their therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35991410P | 2010-06-30 | 2010-06-30 | |
| PCT/EP2010/067781 WO2011061271A1 (en) | 2009-11-20 | 2010-11-18 | Substituted carbamoylmethylamino acetic acid derivatives as novel nep inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20120074A7 true CU20120074A7 (en) | 2014-01-29 |
| CU24125B1 CU24125B1 (en) | 2015-08-27 |
Family
ID=52394791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CUP2012000074A CU24125B1 (en) | 2010-06-30 | 2010-11-18 | DERIVATIVES OF CARBAMOIL-METHYL-AMINO-ACETIC ACID REPLACED AS NOVEDOUS NEP INHIBITORS |
Country Status (1)
| Country | Link |
|---|---|
| CU (1) | CU24125B1 (en) |
-
2010
- 2010-11-18 CU CUP2012000074A patent/CU24125B1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CU24125B1 (en) | 2015-08-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant of patent |