CU20100259A7 - PIRIMIDINE DERIVATIVES AS QUINASA INHIBITORS - Google Patents
PIRIMIDINE DERIVATIVES AS QUINASA INHIBITORSInfo
- Publication number
- CU20100259A7 CU20100259A7 CU20100259A CU20100259A CU20100259A7 CU 20100259 A7 CU20100259 A7 CU 20100259A7 CU 20100259 A CU20100259 A CU 20100259A CU 20100259 A CU20100259 A CU 20100259A CU 20100259 A7 CU20100259 A7 CU 20100259A7
- Authority
- CU
- Cuba
- Prior art keywords
- derivatives
- formula
- quinasa
- inhibitors
- pirimidine derivatives
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 102100033793 ALK tyrosine kinase receptor Human genes 0.000 abstract 2
- 101710168331 ALK tyrosine kinase receptor Proteins 0.000 abstract 2
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 abstract 2
- 102000013275 Somatomedins Human genes 0.000 abstract 2
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 abstract 1
- 150000003230 pyrimidines Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La invención proporciona novedosos derivados de pirimidina de la fórmula 1: ESPACIO PARA LA FÓRMULA y composiciones farmacéuticas de los mismos, y métodos para utilizar estos compuestos. Por ejemplo, los derivados e pirimidina de la invención se pueden utilizar para tratar, aminorar o prevenir una condición que responda a la inhibición del factor de crecimiento tipo insulina (IGF-1R) o de la cinasa de linfoma anaplásico (ALK).The invention provides novel pyrimidine derivatives of the formula 1: SPACE FOR THE FORMULA and pharmaceutical compositions thereof, and methods for using these compounds. For example, the derivatives and pyrimidine of the invention can be used to treat, ameliorate or prevent a condition that responds to the inhibition of insulin-like growth factor (IGF-1R) or anaplastic lymphoma kinase (ALK).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15543409P | 2009-02-25 | 2009-02-25 | |
| PCT/US2009/048428 WO2010002655A2 (en) | 2008-06-25 | 2009-06-24 | Compounds and compositions as kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20100259A7 true CU20100259A7 (en) | 2011-11-15 |
| CU23952B1 CU23952B1 (en) | 2013-10-29 |
Family
ID=45000174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU2010000259A CU23952B1 (en) | 2009-02-25 | 2010-12-23 | PIRIMIDINE DERIVATIVES AS QUINASA INHIBITORS |
Country Status (1)
| Country | Link |
|---|---|
| CU (1) | CU23952B1 (en) |
-
2010
- 2010-12-23 CU CU2010000259A patent/CU23952B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CU23952B1 (en) | 2013-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Lapse (for not paying fees) |