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CU20090064A7 - Nuevos derivados de benzamida como antagonistas de la bradiquinina - Google Patents

Nuevos derivados de benzamida como antagonistas de la bradiquinina

Info

Publication number
CU20090064A7
CU20090064A7 CU2009000064A CU20090064A CU20090064A7 CU 20090064 A7 CU20090064 A7 CU 20090064A7 CU 2009000064 A CU2009000064 A CU 2009000064A CU 20090064 A CU20090064 A CU 20090064A CU 20090064 A7 CU20090064 A7 CU 20090064A7
Authority
CU
Cuba
Prior art keywords
antagonists
bradiquinina
benzamida
new derivatives
formula
Prior art date
Application number
CU2009000064A
Other languages
English (en)
Other versions
CU23857B1 (es
Inventor
Monika Vastag
Eva Szentirmay
Katalin Hornok
Gyula Beke
Eva Schmidt
Gyoergy Keseru
Istvan Vago
BOZO Eva KOVACSNE
Sandor Farkas
Original Assignee
Richter Gedeon Vegyseszeti Gyar Rt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyseszeti Gyar Rt filed Critical Richter Gedeon Vegyseszeti Gyar Rt
Publication of CU20090064A7 publication Critical patent/CU20090064A7/es
Publication of CU23857B1 publication Critical patent/CU23857B1/es

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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
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Abstract

La presente inven ción se refiere a nuevos derivados de fenilsulfamoilbenzamida de fórmula (I) ESPACIO PARA FÓRMULA en la cual R1-R5 y Z son como se definen en las reivindicaciones, y los antípodas ópticos o racematos y/o sales y/o hidratos y/o solvatos de los mismos, los cuales son antagonistas selectivos de la bradiquinina B1, aprocesos para producir estos mismos compuestos, a las composiciones farmacológicas que los contienen y a su uso en la terapia o prevención de estados dolorosos e inflamatorios.
CU20090064A 2006-10-27 2009-04-22 Nuevos derivados de benzamida como antagonistas de la bradiquinina CU23857B1 (es)

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HU0600808A HUP0600808A3 (en) 2006-10-27 2006-10-27 New benzamide derivatives as bradykinin antagonists, process for their preparation and pharmaceutical compositions containing them
PCT/HU2007/000102 WO2008068540A1 (en) 2006-10-27 2007-10-27 New benzamide derivatives as bradykinin antagonists

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HUP0600809A3 (en) * 2006-10-27 2008-09-29 Richter Gedeon Nyrt New phenylsulfamoyl-benzamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them
CA2703290A1 (en) * 2007-10-27 2009-04-30 Richter Gedeon Nyrt. New non-peptide derivatives as bradykinin b1 antagonists
CN102159077A (zh) * 2008-08-21 2011-08-17 吉瑞工厂 用于治疗神经性疼痛的方法
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KR101676850B1 (ko) 2015-04-23 2016-11-18 한일화섬 주식회사 내구성이 우수한 스피커용 댐퍼 및 그 제조 방법
TW202202495A (zh) 2020-03-26 2022-01-16 匈牙利商羅特格登公司 作為ｇａｍｍａ－胺基丁酸Ａ受體次單元ａｌｐｈａ ５受體調節劑之㖠啶及吡啶并〔３，４－ｃ〕嗒𠯤衍生物
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HUP0600809A3 (en) 2006-10-27 2008-09-29 Richter Gedeon Nyrt New phenylsulfamoyl-benzamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them
CA2703290A1 (en) 2007-10-27 2009-04-30 Richter Gedeon Nyrt. New non-peptide derivatives as bradykinin b1 antagonists
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