CS249576B1 - 6-purinyl n-(2-chlorethyl)carbamate and thiocarbamate and method of their production - Google Patents

6-purinyl n-(2-chlorethyl)carbamate and thiocarbamate and method of their production Download PDF

Info

Publication number: CS249576B1
Authority: CS; Czechoslovakia
Prior art keywords: animals; tumor; purinyl; chloroethyl; dose
Prior art date: 1984-12-22

Application number

CS8410291A

Other languages

Czech (cs)

English (en)

Other versions

CS1029184A1 (en

Inventor

Antonin Cerny

Jiri Krepelka

Milan Melka

Milan Miko

Stanislava Pokorna

Irena Kejhova

Ruzena Reichlova

Marta Beitova

Jaroslava Grimova

Original Assignee

Antonin Cerny

Jiri Krepelka

Milan Melka

Milan Miko

Stanislava Pokorna

Irena Kejhova

Ruzena Reichlova

Marta Beitova

Jaroslava Grimova

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-12-22

Filing date

1984-12-22

Publication date

1987-04-16

1984-12-22 Application filed by Antonin Cerny, Jiri Krepelka, Milan Melka, Milan Miko, Stanislava Pokorna, Irena Kejhova, Ruzena Reichlova, Marta Beitova, Jaroslava Grimova filed Critical Antonin Cerny

1984-12-22 Priority to CS8410291A priority Critical patent/CS249576B1/cs

1985-08-15 Publication of CS1029184A1 publication Critical patent/CS1029184A1/cs

1985-12-12 Priority to CA000497510A priority patent/CA1260935A/en

1985-12-19 Priority to FI855089A priority patent/FI82246C/fi

1985-12-19 Priority to EP85309296A priority patent/EP0186454B1/en

1985-12-20 Priority to JP60285848A priority patent/JPS61186382A/ja

1985-12-23 Priority to US06/812,139 priority patent/US4720497A/en

1987-04-16 Publication of CS249576B1 publication Critical patent/CS249576B1/cs

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/36—Sulfur atom
- C07D473/38—Sulfur atom attached in position 6
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/28—Oxygen atom
- C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CS8410291A 1984-12-22 1984-12-22 6-purinyl n-(2-chlorethyl)carbamate and thiocarbamate and method of their production CS249576B1 (en)

Priority Applications (6)

Application Number	Priority Date	Filing Date	Title
CS8410291A CS249576B1 (en)	1984-12-22	1984-12-22	6-purinyl n-(2-chlorethyl)carbamate and thiocarbamate and method of their production
CA000497510A CA1260935A (en)	1984-12-22	1985-12-12	6-purinyl n-(2-chlorethyl) carbamate and thiocarbamate and a process for their preparation
FI855089A FI82246C (fi)	1984-12-22	1985-12-19	Foerfarande foer framstaellning av ett farmakologiskt aktiva 6-purinyl-n-/2-kloretyl/karbamat eller tiokarbamat.
EP85309296A EP0186454B1 (en)	1984-12-22	1985-12-19	6-purinyl n-(2-chloroethyl) carbamate and thiocarbamate, a process for their preparation and use thereof
JP60285848A JPS61186382A (ja)	1984-12-22	1985-12-20	６−プリニルｎ−（２−クロロエチル）カルバメ−ト及びチオカルバメ−ト、及びそれらの製法
US06/812,139 US4720497A (en)	1984-12-22	1985-12-23	6-purinyl N-/2-chloroethyl/carbamate and thiocarbamate and process for the preparation thereof

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CS8410291A CS249576B1 (en)	1984-12-22	1984-12-22	6-purinyl n-(2-chlorethyl)carbamate and thiocarbamate and method of their production

Publications (2)

Publication Number	Publication Date
CS1029184A1 CS1029184A1 (en)	1985-08-15
CS249576B1 true CS249576B1 (en)	1987-04-16

Family

ID=5448550

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CS8410291A CS249576B1 (en)	1984-12-22	1984-12-22	6-purinyl n-(2-chlorethyl)carbamate and thiocarbamate and method of their production

Country Status (6)

Country	Link
US (1)	US4720497A (fi)
EP (1)	EP0186454B1 (fi)
JP (1)	JPS61186382A (fi)
CA (1)	CA1260935A (fi)
CS (1)	CS249576B1 (fi)
FI (1)	FI82246C (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CS249576B1 (en) *	1984-12-22	1987-04-16	Antonin Cerny	6-purinyl n-(2-chlorethyl)carbamate and thiocarbamate and method of their production
US6866797B1 (en)	2000-08-03	2005-03-15	Bj Services Company	Corrosion inhibitors and methods of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH501652A (de) *	1966-07-01	1971-01-15	Spofa Vereinigte Pharma Werke	Verfahren zur Herstellung von N-( -(6-Purinylthio)-valeryl)-aminosäureestern
DK172081A (da) *	1980-04-21	1981-10-22	Merck & Co Inc	Mercaptoforbindelse og fremgangsmaade til fremstilling deraf
CS249576B1 (en) *	1984-12-22	1987-04-16	Antonin Cerny	6-purinyl n-(2-chlorethyl)carbamate and thiocarbamate and method of their production

1984
- 1984-12-22 CS CS8410291A patent/CS249576B1/cs unknown
1985
- 1985-12-12 CA CA000497510A patent/CA1260935A/en not_active Expired
- 1985-12-19 FI FI855089A patent/FI82246C/fi not_active IP Right Cessation
- 1985-12-19 EP EP85309296A patent/EP0186454B1/en not_active Expired - Lifetime
- 1985-12-20 JP JP60285848A patent/JPS61186382A/ja active Granted
- 1985-12-23 US US06/812,139 patent/US4720497A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CS1029184A1 (en)	1985-08-15
US4720497A (en)	1988-01-19
JPH0586791B2 (fi)	1993-12-14
FI82246C (fi)	1991-02-11
JPS61186382A (ja)	1986-08-20
EP0186454A3 (en)	1989-03-08
FI82246B (fi)	1990-10-31
FI855089A (fi)	1986-06-23
EP0186454A2 (en)	1986-07-02
CA1260935A (en)	1989-09-26
FI855089A0 (fi)	1985-12-19
EP0186454B1 (en)	1992-04-08

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