CS247164B2 - Method of 8-aminoacylamino-4-aryl-2-methyl-1,2,3,4-tetrahydroisoquinoline new derivatives production - Google Patents

Method of 8-aminoacylamino-4-aryl-2-methyl-1,2,3,4-tetrahydroisoquinoline new derivatives production Download PDF

Info

Publication number: CS247164B2
Authority: CS; Czechoslovakia
Prior art keywords: methyl; lower alkyl; ether; formula; ethanol
Prior art date: 1982-06-04

Application number

CS833984A

Other languages

Czech (cs)

English (en)

Inventor

Gyula Deak

Erzsebet Zara

Lajos Gyoergy

Marton Fekete

Margit Doda

Andras Seregi

Bela Kanyicska

Erzsebet Toth

Maria Horvath

Sandor Manyai

Frigyes Goergenyi

Gyoergyi Vaszovics

Original Assignee

Egyt Gyogyszervegyeszeti Gyar

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-06-04

Filing date

1983-06-02

Publication date

1986-12-18

1982-06-04 Priority claimed from HU821799A external-priority patent/HU190019B/hu

1982-06-04 Priority claimed from HU821797A external-priority patent/HU186518B/hu

1982-06-04 Priority claimed from HU179882A external-priority patent/HU186519B/hu

1983-06-02 Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar

1984-03-05 Priority to CS841560A priority Critical patent/CS247177B2/cs

1984-03-05 Priority to CS841561A priority patent/CS247178B2/cs

1984-08-13 Priority to CS846141A priority patent/CS247182B2/cs

1984-11-16 Priority to CS848748A priority patent/CS247188B2/cs

1986-12-18 Publication of CS247164B2 publication Critical patent/CS247164B2/cs

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

CS833984A 1982-06-04 1983-06-02 Method of 8-aminoacylamino-4-aryl-2-methyl-1,2,3,4-tetrahydroisoquinoline new derivatives production CS247164B2 (en)

Priority Applications (4)

Application Number	Priority Date	Filing Date	Title
CS841560A CS247177B2 (cs)	1982-06-04	1984-03-05	Způsob výroby nových derivátů 8-karbamoylamino-4-aryl-2-methyl 1,2,3,4-tetrahydroisochinolinu
CS841561A CS247178B2 (cs)	1982-06-04	1984-03-05	Způsob výroby nových derivátů 8-alkoxykarbonylamino-4-aryl2-methyl-1,2,3,4-tetrahydroisochinolinu
CS846141A CS247182B2 (cs)	1982-06-04	1984-08-13	Způsob výroby nových derivátů 8-karbamoylamino-4-aryl-2-methyl -1,2,3,4-tetrahydroisochinolinu
CS848748A CS247188B2 (cs)	1982-06-04	1984-11-16	Způsob výroby nových derivátů 8-alkoxykarbonylamino-4-aryl-2-methyl-1,2,3,4-tetrahydroisochinolinu

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
HU821799A HU190019B (hu)	1982-06-04	1982-06-04	Eljárás 8-(alkoxi'karbonil-amino)-4-áril-2-metil-tetrahidro -izokinolin-származékok előállítására
HU821797A HU186518B (en)	1982-06-04	1982-06-04	Process for producing 8-bracket-amino-acyl-amino-bracket closed-4-aryl-2-methyl-1,2,3,4-tetrahydro-isoquinoline derivatives
HU179882A HU186519B (en)	1982-06-04	1982-06-04	Process for producing 8-bracket-carbamoyl-amino-bracket-closed-4-aryl-2-methyl-tetrahydro-isoquinoline derivatives

Publications (1)

Publication Number	Publication Date
CS247164B2 true CS247164B2 (en)	1986-12-18

Family

ID=27269976

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CS833984A CS247164B2 (en)	1982-06-04	1983-06-02	Method of 8-aminoacylamino-4-aryl-2-methyl-1,2,3,4-tetrahydroisoquinoline new derivatives production

Country Status (19)

Country	Link
US (1)	US4537895A (xx)
AT (1)	AT384806B (xx)
CA (1)	CA1198733A (xx)
CH (1)	CH654833A5 (xx)
CS (1)	CS247164B2 (xx)
DD (1)	DD210684A5 (xx)
DE (1)	DE3320028A1 (xx)
DK (1)	DK254983A (xx)
ES (5)	ES522976A0 (xx)
FI (1)	FI831982L (xx)
FR (1)	FR2528044B1 (xx)
GB (1)	GB2124209B (xx)
GR (1)	GR77482B (xx)
NL (1)	NL8301960A (xx)
PH (1)	PH19604A (xx)
PL (5)	PL140035B1 (xx)
SE (1)	SE8303131L (xx)
SU (4)	SU1207393A3 (xx)
YU (2)	YU42865B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2038646T3 (es) *	1987-11-03	1993-08-01	S O ®Pharmachim®	Procedimiento de obtencion de 4-fenilo-1,2,3,4-tetrahidroisochinolina como medicamentos para la ulcera.
ITTO20060599A1 (it)	2006-08-11	2008-02-12	Itw Construction Products Ital	Organo di ancoraggio di strutture in legno o metallo ad una parete

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1153471A (en) *	1965-04-09	1969-05-29	Wellcome Found	Antiprotozoal 8-Aminoquinoline Derivatives
US3674791A (en) *	1968-03-26	1972-07-04	Marion Laboratories Inc	Benzamido 2 lower alkyl decahydroisoquinolines
GB1453606A (en) *	1972-12-22	1976-10-27	Siphar Sa	Method for synthesis of plus-minus-glaziovine
US3910915A (en) *	1973-07-23	1975-10-07	Searle & Co	1-Aryl-2-{8 (substituted amino)alkanoyl{9 -1,2,3,4-tetrahydroisoquinolines
DE2724610A1 (de) *	1977-06-01	1978-12-14	Hoechst Ag	4-phenyl-8-amino-tetrahydroisochinoline
DE2811361A1 (de) *	1978-03-16	1979-09-27	Hoechst Ag	Neue isochinolinaldehyde und verfahren zu ihrer herstellung
DE2818423A1 (de) *	1978-04-27	1979-11-08	Hoechst Ag	Neue isochinolinderivate und verfahren zu ihrer herstellung

1983
- 1983-05-30 PH PH28981A patent/PH19604A/en unknown
- 1983-06-01 PL PL1983249637A patent/PL140035B1/pl unknown
- 1983-06-01 PL PL1983242311A patent/PL139768B1/pl unknown
- 1983-06-01 PL PL1983249638A patent/PL140034B1/pl unknown
- 1983-06-01 PL PL1983249636A patent/PL140094B1/pl unknown
- 1983-06-01 PL PL1983249639A patent/PL140164B1/pl unknown
- 1983-06-02 SE SE8303131A patent/SE8303131L/xx not_active Application Discontinuation
- 1983-06-02 CS CS833984A patent/CS247164B2/cs unknown
- 1983-06-02 NL NL8301960A patent/NL8301960A/xx not_active Application Discontinuation
- 1983-06-02 GR GR71542A patent/GR77482B/el unknown
- 1983-06-02 YU YU1222/83A patent/YU42865B/xx unknown
- 1983-06-02 FI FI831982A patent/FI831982L/fi not_active Application Discontinuation
- 1983-06-03 DE DE19833320028 patent/DE3320028A1/de active Granted
- 1983-06-03 CH CH3048/83A patent/CH654833A5/de not_active IP Right Cessation
- 1983-06-03 US US06/500,969 patent/US4537895A/en not_active Expired - Fee Related
- 1983-06-03 DD DD83251735A patent/DD210684A5/de unknown
- 1983-06-03 AT AT0204383A patent/AT384806B/de not_active IP Right Cessation
- 1983-06-03 FR FR8309233A patent/FR2528044B1/fr not_active Expired
- 1983-06-03 GB GB08315293A patent/GB2124209B/en not_active Expired
- 1983-06-03 ES ES522976A patent/ES522976A0/es active Granted
- 1983-06-03 CA CA000429646A patent/CA1198733A/en not_active Expired
- 1983-06-03 DK DK254983A patent/DK254983A/da not_active Application Discontinuation
- 1983-06-03 SU SU833604150A patent/SU1207393A3/ru active
1984
- 1984-03-22 SU SU843713729A patent/SU1329620A3/ru active
- 1984-03-22 SU SU843714140A patent/SU1375130A3/ru active
1985
- 1985-05-14 ES ES543158A patent/ES8607940A1/es not_active Expired
- 1985-05-14 ES ES543157A patent/ES8607939A1/es not_active Expired
- 1985-07-10 SU SU853922993A patent/SU1400505A3/ru active
- 1985-09-30 YU YU1554/85A patent/YU43419B/xx unknown
1986
- 1986-02-01 ES ES551560A patent/ES8702361A1/es not_active Expired
- 1986-02-01 ES ES551559A patent/ES8701729A1/es not_active Expired

Also Published As

Publication number	Publication date
DE3320028C2 (xx)	1988-06-23
YU122283A (en)	1986-02-28
PL249638A1 (en)	1985-07-16
ES8602678A1 (es)	1985-12-01
DK254983A (da)	1983-12-05
YU155485A (en)	1986-02-28
SE8303131D0 (sv)	1983-06-02
PL139768B1 (en)	1987-02-28
GB8315293D0 (en)	1983-07-06
PL140035B1 (en)	1987-03-31
DD210684A5 (de)	1984-06-20
GB2124209B (en)	1985-09-25
SU1400505A3 (ru)	1988-05-30
FR2528044A1 (fr)	1983-12-09
US4537895A (en)	1985-08-27
PL140034B1 (en)	1987-03-31
SU1375130A3 (ru)	1988-02-15
DK254983D0 (da)	1983-06-03
SU1329620A3 (ru)	1987-08-07
CA1198733A (en)	1985-12-31
CH654833A5 (de)	1986-03-14
ES8702361A1 (es)	1986-12-16
FI831982L (fi)	1983-12-05
GB2124209A (en)	1984-02-15
SE8303131L (sv)	1983-12-05
YU43419B (en)	1989-06-30
DE3320028A1 (de)	1983-12-08
ES8701729A1 (es)	1986-12-16
ES522976A0 (es)	1985-12-01
ES8607939A1 (es)	1986-06-16
PL249639A1 (en)	1985-07-16
PL249637A1 (en)	1985-07-16
ATA204383A (de)	1987-06-15
ES8607940A1 (es)	1986-06-16
GR77482B (xx)	1984-09-24
PH19604A (en)	1986-05-27
SU1207393A3 (ru)	1986-01-23
YU42865B (en)	1988-12-31
PL140094B1 (en)	1987-03-31
FR2528044B1 (fr)	1986-01-03
NL8301960A (nl)	1984-01-02
ES551559A0 (es)	1986-12-16
PL242311A1 (en)	1985-01-16
FI831982A0 (fi)	1983-06-02
ES543158A0 (es)	1986-06-16
AT384806B (de)	1988-01-11
PL140164B1 (en)	1987-03-31
ES551560A0 (es)	1986-12-16
ES543157A0 (es)	1986-06-16
PL249636A1 (en)	1985-07-16

Publication	Publication Date	Title
US4076820A (en)	1978-02-28	Benzoquinolizines and hypotensive compositions containing them
EP0025111B1 (en)	1984-07-25	3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
EP0237573B1 (en)	1992-01-15	Novel benzothiazine derivatives
AU598149B2 (en)	1990-06-14	2-((4-piperidyl)methyl)-1,2,3,4-tetrahydroisoquinoline derivatives, their preparation and their application in therapy
US4153789A (en)	1979-05-08	Phenylindolines
US3923813A (en)	1975-12-02	Derivatives of 2-aminoindanes
US3819628A (en)	1974-06-25	2-phenyl-4-substituted amino-quinazolines and nitrates thereof
US3314963A (en)	1967-04-18	Azabenzocycloalkane-n-carboxamidines
US3989709A (en)	1976-11-02	Fused ring benzimidazole derivatives
US3940397A (en)	1976-02-24	2-[(Substituted-piperazinyl)alkyl]-1H-benz[de]isoquinoline-1,3(2H)-diones
CS247164B2 (en)	1986-12-18	Method of 8-aminoacylamino-4-aryl-2-methyl-1,2,3,4-tetrahydroisoquinoline new derivatives production
US4208420A (en)	1980-06-17	New benzo [d] thiazole derivatives, process for their preparation and their therapeutic applications
US3277085A (en)	1966-10-04	Nx c cha-chjx o oh
JPS61293976A (ja)	1986-12-24	ベンゾチアゼピン誘導体
US4983606A (en)	1991-01-08	Pharmaceutically-active phthalazine compounds
EP0136736B1 (en)	1987-10-28	1-(4'-alkylthiophenyl)-2-amino-1,3-propanediol n-substituted derivatives
CA1133483A (en)	1982-10-12	Hexahydro-trans-pyridoindole neuroleptic agents
GB2081261A (en)	1982-02-17	Condensed as-triazine derivatives and process for preparing the same
US4360673A (en)	1982-11-23	5 Phenyl-1,3-alkano-1,2,3,4,4a,9b-hexahydropyrido [4,3-b]indoles
US4684657A (en)	1987-08-04	Benzenesulphonamide derivatives
EP0066799A2 (en)	1982-12-15	Nicotinic acid derivatives
US3210358A (en)	1965-10-05	Substituted 4-amino carbostyrils
US4654351A (en)	1987-03-31	Bis(substituted methyl)-methyl-isoquinoline derivatives and pharmaceutical compositions containing them
US3476755A (en)	1969-11-04	8,13-diazasteroids
US4048177A (en)	1977-09-13	Certain 2-substituted 4-phenylquinoline-4-ols