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CS214759B2 - Method of making the piperidin derivatives of esters of 4,5-diacyl-3-hydroxy-pyrrol-2-carboxyl acid - Google Patents

Method of making the piperidin derivatives of esters of 4,5-diacyl-3-hydroxy-pyrrol-2-carboxyl acid Download PDF

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Publication number
CS214759B2
CS214759B2 CS806922A CS692280A CS214759B2 CS 214759 B2 CS214759 B2 CS 214759B2 CS 806922 A CS806922 A CS 806922A CS 692280 A CS692280 A CS 692280A CS 214759 B2 CS214759 B2 CS 214759B2
Authority
CS
Czechoslovakia
Prior art keywords
hydroxy
formula
acid
carboxylic acid
methyl
Prior art date
Application number
CS806922A
Other languages
Czech (cs)
English (en)
Inventor
Fritz-Frieder Frickel
Albrecht Franke
Philipsborn Gerda Von
Claus D Mueller
Dieter Lenke
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of CS214759B2 publication Critical patent/CS214759B2/cs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CS806922A 1979-10-13 1980-10-13 Method of making the piperidin derivatives of esters of 4,5-diacyl-3-hydroxy-pyrrol-2-carboxyl acid CS214759B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792941597 DE2941597A1 (de) 1979-10-13 1979-10-13 Piperidinderivate von 4,5-dialkyl-3-hydroxy-pyrrol-2-carbonsaeureestern, ihre herstellung und diese enthaltende pharmazeutische zubereitungen

Publications (1)

Publication Number Publication Date
CS214759B2 true CS214759B2 (en) 1982-05-28

Family

ID=6083464

Family Applications (1)

Application Number Title Priority Date Filing Date
CS806922A CS214759B2 (en) 1979-10-13 1980-10-13 Method of making the piperidin derivatives of esters of 4,5-diacyl-3-hydroxy-pyrrol-2-carboxyl acid

Country Status (18)

Country Link
US (1) US4315939A (fi)
EP (1) EP0027928B1 (fi)
JP (1) JPS5663956A (fi)
AT (1) ATE2746T1 (fi)
AU (1) AU532982B2 (fi)
CA (1) CA1155124A (fi)
CS (1) CS214759B2 (fi)
DE (2) DE2941597A1 (fi)
DK (1) DK430380A (fi)
ES (1) ES495831A0 (fi)
FI (1) FI70013C (fi)
HU (1) HU184936B (fi)
IE (1) IE50796B1 (fi)
IL (1) IL61212A (fi)
NO (1) NO803047L (fi)
SU (1) SU957768A3 (fi)
YU (1) YU262380A (fi)
ZA (1) ZA806282B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0076072B1 (en) * 1981-09-24 1987-05-13 BEECHAM - WUELFING GmbH & Co. KG Sulphonamides
US4558129A (en) * 1983-05-18 1985-12-10 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade
US4567264A (en) * 1983-05-18 1986-01-28 Syntex (U.S.A.) Inc. Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry
AU4977899A (en) * 1998-07-27 2000-02-21 Eli Lilly And Company Treatment of anxiety disorders
US6242450B1 (en) 1998-07-27 2001-06-05 Eli Lilly And Company 5-HT1F antagonists
UY33388A (es) * 2010-05-17 2011-12-01 Glaxo Group Ltd Nuevos procesos para la preparacion de compuestos de pirimidinona

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1527E (fr) * 1902-08-20 1903-08-12 Hermann Hilbert Procédé pour extrait la gélatine et la colle des os
DE1720033A1 (de) * 1966-03-02 1971-05-19 Yoshitomi Pharmaceutical Neue Indolderivate und Verfahren zu ihrer Herstellung
CH489497A (de) * 1967-01-25 1970-04-30 Geigy Ag J R Verfahren zur Herstellung von neuen Indolderivaten
US3860609A (en) * 1969-05-27 1975-01-14 Novo Terapeutisk Labor As 3-aminoalkyloxyindoles
DE2630152A1 (de) * 1976-07-05 1978-01-19 Cassella Farbwerke Mainkur Ag Derivate des 1-phenoxy-propan-2-ols- und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
HU184936B (en) 1984-11-28
FI70013C (fi) 1986-09-12
ES8200363A1 (es) 1981-11-01
CA1155124A (en) 1983-10-11
DK430380A (da) 1981-04-14
ATE2746T1 (de) 1983-03-15
IL61212A0 (en) 1980-12-31
JPS648632B2 (fi) 1989-02-14
US4315939A (en) 1982-02-16
FI802960A (fi) 1981-04-14
EP0027928B1 (de) 1983-03-09
AU6320480A (en) 1981-04-16
YU262380A (en) 1983-01-21
SU957768A3 (ru) 1982-09-07
DE2941597A1 (de) 1981-04-23
DE3062300D1 (en) 1983-04-14
IE50796B1 (en) 1986-07-23
EP0027928A3 (en) 1981-05-20
AU532982B2 (en) 1983-10-20
IL61212A (en) 1983-09-30
ZA806282B (en) 1981-10-28
ES495831A0 (es) 1981-11-01
NO803047L (no) 1981-04-14
EP0027928A2 (de) 1981-05-06
JPS5663956A (en) 1981-05-30
IE802102L (en) 1981-04-13
FI70013B (fi) 1986-01-31

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