CO6150193A2 - Terapia tumoral con anticuerpo anti-vegf - Google Patents
Terapia tumoral con anticuerpo anti-vegfInfo
- Publication number
- CO6150193A2 CO6150193A2 CO09018558A CO09018558A CO6150193A2 CO 6150193 A2 CO6150193 A2 CO 6150193A2 CO 09018558 A CO09018558 A CO 09018558A CO 09018558 A CO09018558 A CO 09018558A CO 6150193 A2 CO6150193 A2 CO 6150193A2
- Authority
- CO
- Colombia
- Prior art keywords
- medicament
- antibody
- treatment
- use according
- administered
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
1.- El uso de un anticuerpo anti-VEGF para la elaboración de un medicamento para el tratamiento de un paciente que padece una recaída de cáncer HER2 positivo, durante o después del tratamiento con un anticuerpo anti-HER2. 2.- El uso de acuerdo con la reivindicación 1 que se caracteriza porque dicho medicamento se administra al paciente durante el tratamiento con un anticuerpo anti-HER2. 3.- El uso de acuerdo con la reivindicación 2 que se caracteriza porque dicho medicamento se administra durante una monoterapia de primera elección con un anticuerpo anti-HER2. 4.- El uso de acuerdo con la reivindicación 1 que se caracteriza porque dicho medicamento se administra tras el tratamiento con un anticuerpo anti-HER2. 5.- El uso de acuerdo con la reivindicación 4 que se caracteriza porque dicho medicamento se administra tras una monoterapia de primera elección con un anticuerpo antiHER2. 6.- El uso de un anticuerpo anti-VEGF para la elaboración de un medicamento para prevenir o reducir la metástasis en un paciente, que padece una recaída de cáncer HER2 positivo, durante o después del tratamiento con un anticuerpo anti-HER2.7.- El uso de acuerdo con la reivindicación 6 que se caracteriza porque dicho medicamento se administra durante el tratamiento con un anticuerpo anti-HER2. 8.- El uso de acuerdo con la reivindicación 7 que se caracteriza porque dicho medicamento se administra durante una monoterapia de primera elección con un anticuerpo anti-HER2. 9.- El uso de acuerdo con la reivindicación 6 que se caracteriza porque dicho medicamento se administra tras el tratamiento con un anticuerpo anti-HER2. 10.- El uso de acuerdo con la reivindicación 9 que se caracteriza porque dicho medicamento se administra tras una monoterapia de primera elección con un anticuerpo anti-HER2. 11.- El uso de acuerdo con cualquiera de las reivindicaciones 1 a 10, que se caracteriza porque dicho anti-VEGF es bevacizumab. 12.- El uso de cualquiera de las reivindicaciones 1 a 11, que se caracteriza porque dicho anticuerpo anti-HER2 es trastuzumab.13.- Un anticuerpo anti-VEGF para el tratamiento de un paciente que padece una recaída de cáncer HER2 positivo, durante o después del tratamiento con un anticuerpo anti-HER2.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06017330 | 2006-08-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6150193A2 true CO6150193A2 (es) | 2010-04-20 |
Family
ID=37607207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO09018558A CO6150193A2 (es) | 2006-08-21 | 2009-02-24 | Terapia tumoral con anticuerpo anti-vegf |
Country Status (29)
| Country | Link |
|---|---|
| US (6) | US20080050385A1 (es) |
| EP (2) | EP2441472B1 (es) |
| JP (3) | JP2010501498A (es) |
| KR (1) | KR101136763B1 (es) |
| CN (1) | CN101505792B (es) |
| AR (1) | AR062419A1 (es) |
| AU (1) | AU2007287794B2 (es) |
| BR (1) | BRPI0715829A2 (es) |
| CA (1) | CA2660681A1 (es) |
| CL (1) | CL2007002404A1 (es) |
| CO (1) | CO6150193A2 (es) |
| CR (1) | CR10590A (es) |
| DK (1) | DK2056874T3 (es) |
| ES (2) | ES2392630T3 (es) |
| HK (1) | HK1134441A1 (es) |
| IL (2) | IL196810A0 (es) |
| MA (1) | MA30654B1 (es) |
| MX (1) | MX2009001715A (es) |
| MY (1) | MY150756A (es) |
| NO (1) | NO20090450L (es) |
| NZ (1) | NZ574580A (es) |
| PE (1) | PE20080911A1 (es) |
| PL (1) | PL2056874T3 (es) |
| RU (1) | RU2528884C2 (es) |
| SG (1) | SG174090A1 (es) |
| SI (1) | SI2056874T1 (es) |
| TW (2) | TW200825106A (es) |
| WO (1) | WO2008022746A1 (es) |
| ZA (1) | ZA200901200B (es) |
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| PL400669A1 (pl) * | 2000-05-19 | 2012-11-05 | Genentech, Inc. | Genowa próba wykrywania odpowiedzi na antagoniste ErbB dla poprawienia prawdopodobienstwa i skutecznosci leczenia raka |
| PT1771482E (pt) * | 2004-07-22 | 2014-11-03 | Genentech Inc | Composição de anticorpo her2 |
| JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| JP2008523073A (ja) * | 2004-12-07 | 2008-07-03 | ジェネンテック・インコーポレーテッド | Ｈｅｒ阻害剤を用いた治療のための患者の選択 |
| JP2008528486A (ja) | 2005-01-21 | 2008-07-31 | ジェネンテック・インコーポレーテッド | Ｈｅｒ抗体の一定投薬 |
| RU2404806C2 (ru) | 2005-02-23 | 2010-11-27 | Дженентек, Инк. | Продление времени до прогрессирования заболевания или продолжительности жизни у онкологических больных с применением ингибиторов димеризации her |
| PE20070207A1 (es) * | 2005-07-22 | 2007-03-09 | Genentech Inc | Tratamiento combinado de los tumores que expresan el her |
| MX2009001715A (es) * | 2006-08-21 | 2009-02-25 | Hoffmann La Roche | Terapia tumoral con un anticuerpo anti-vegf. |
| JP2010520225A (ja) | 2007-03-02 | 2010-06-10 | ジェネンテック， インコーポレイテッド | 低ｈｅｒ３発現に基づくｈｅｒ二量化インヒビターに対する応答を予測する方法 |
| TWI472339B (zh) | 2008-01-30 | 2015-02-11 | Genentech Inc | 包含結合至ｈｅｒ２結構域ii之抗體及其酸性變異體的組合物 |
| BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
| EP2575880B1 (en) | 2010-05-27 | 2019-01-16 | Genmab A/S | Monoclonal antibodies against her2 epitope |
| AU2011257121A1 (en) | 2010-05-27 | 2013-01-10 | Genmab A/S | Monoclonal antibodies against HER2 |
| KR20130091746A (ko) * | 2010-07-19 | 2013-08-19 | 에프. 호프만-라 로슈 아게 | 췌장암의 치료를 위한 베바시주맙 병용 치료법을 위한 혈장 생체마커 |
| ES2620255T3 (es) * | 2010-08-20 | 2017-06-28 | Novartis Ag | Anticuerpos para el receptor del factor de crecimiento epidérmico 3 (HER3) |
| CA2832389A1 (en) | 2011-04-20 | 2012-10-26 | Genmab A/S | Bispecific antibodies against her2 and cd3 |
| PL4241849T3 (pl) | 2011-10-14 | 2025-01-13 | F. Hoffmann-La Roche Ag | Zastosowania i wyrób przemysłowy zawierający pertuzumab, inhibitor dimeryzacji HER2 |
| RU2014125520A (ru) * | 2011-12-05 | 2016-02-10 | Ф. Хоффманн-Ля Рош Аг | Биомаркеры плазмы крови в случае комбинированной терапии бевацизумабом для лечения рака груди |
| WO2013148159A1 (en) * | 2012-03-30 | 2013-10-03 | Fibrogen Inc | Therapeutic methods for peritoneal carcinomatosis |
| NZ751877A (en) | 2013-04-16 | 2020-04-24 | Genentech Inc | Pertuzumab variants and evaluation thereof |
| CN106163558A (zh) | 2014-04-25 | 2016-11-23 | 豪夫迈·罗氏有限公司 | 用曲妥珠单抗‑mcc‑dm1和帕妥珠单抗治疗早期乳腺癌的方法 |
| TW201619200A (zh) * | 2014-10-10 | 2016-06-01 | 麥迪紐有限責任公司 | 人類化抗－ｏｘ４０抗體及其用途 |
| JP6822980B2 (ja) | 2015-05-30 | 2021-01-27 | ジェネンテック， インコーポレイテッド | Ｈｅｒ２陽性転移性乳癌の治療方法 |
| WO2017087280A1 (en) | 2015-11-16 | 2017-05-26 | Genentech, Inc. | Methods of treating her2-positive cancer |
| CN106729743B (zh) | 2015-11-23 | 2021-09-21 | 四川科伦博泰生物医药股份有限公司 | 抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用 |
| TW202140776A (zh) * | 2016-04-26 | 2021-11-01 | 美商美國泰福生技股份有限公司 | 細胞培養基 |
| JP6914336B2 (ja) | 2016-12-28 | 2021-08-04 | ジェネンテック， インコーポレイテッド | 進行したｈｅｒ２発現がんの治療 |
| HUE052551T2 (hu) | 2017-01-17 | 2021-05-28 | Genentech Inc | Szubkután HER2 antitest készítmények |
| JP6992081B2 (ja) | 2017-03-02 | 2022-02-03 | ジェネンテック， インコーポレイテッド | Ｈｅｒ２陽性乳癌のアジュバント治療 |
| EP3615695A1 (en) | 2017-04-24 | 2020-03-04 | Genentech, Inc. | Erbb2/her2 mutations in the transmebrane or juxtamembrane domain |
| AU2020456731A1 (en) | 2020-06-29 | 2023-01-05 | F. Hoffmann-La Roche Ag | Pertuzumab plus trastuzumab fixed dose combination |
| US20230330094A1 (en) * | 2020-09-04 | 2023-10-19 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Combination compositions and methods for treating cancer |
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-
2007
- 2007-08-17 MX MX2009001715A patent/MX2009001715A/es active IP Right Grant
- 2007-08-17 ES ES07786693T patent/ES2392630T3/es active Active
- 2007-08-17 AR ARP070103667A patent/AR062419A1/es unknown
- 2007-08-17 BR BRPI0715829-7A2A patent/BRPI0715829A2/pt not_active Application Discontinuation
- 2007-08-17 CN CN2007800308557A patent/CN101505792B/zh not_active Expired - Fee Related
- 2007-08-17 PL PL07786693T patent/PL2056874T3/pl unknown
- 2007-08-17 CA CA002660681A patent/CA2660681A1/en not_active Abandoned
- 2007-08-17 JP JP2009524943A patent/JP2010501498A/ja active Pending
- 2007-08-17 KR KR1020097003557A patent/KR101136763B1/ko not_active IP Right Cessation
- 2007-08-17 EP EP11193793.4A patent/EP2441472B1/en not_active Revoked
- 2007-08-17 MY MYPI20090667 patent/MY150756A/en unknown
- 2007-08-17 RU RU2009110102/15A patent/RU2528884C2/ru not_active IP Right Cessation
- 2007-08-17 DK DK07786693.7T patent/DK2056874T3/da active
- 2007-08-17 EP EP07786693A patent/EP2056874B1/en not_active Revoked
- 2007-08-17 ES ES11193793.4T patent/ES2546066T3/es active Active
- 2007-08-17 CL CL200702404A patent/CL2007002404A1/es unknown
- 2007-08-17 WO PCT/EP2007/007276 patent/WO2008022746A1/en active Application Filing
- 2007-08-17 NZ NZ574580A patent/NZ574580A/en not_active IP Right Cessation
- 2007-08-17 SG SG2011060142A patent/SG174090A1/en unknown
- 2007-08-17 SI SI200731075T patent/SI2056874T1/sl unknown
- 2007-08-17 AU AU2007287794A patent/AU2007287794B2/en not_active Ceased
- 2007-08-17 US US11/840,279 patent/US20080050385A1/en not_active Abandoned
- 2007-08-20 TW TW096130765A patent/TW200825106A/zh unknown
- 2007-08-20 TW TW099141756A patent/TW201107346A/zh unknown
- 2007-08-20 PE PE2007001129A patent/PE20080911A1/es not_active Application Discontinuation
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2009
- 2009-01-29 NO NO20090450A patent/NO20090450L/no not_active Application Discontinuation
- 2009-01-29 CR CR10590A patent/CR10590A/es not_active Application Discontinuation
- 2009-01-29 IL IL196810A patent/IL196810A0/en unknown
- 2009-02-19 MA MA31650A patent/MA30654B1/fr unknown
- 2009-02-19 ZA ZA2009/01200A patent/ZA200901200B/en unknown
- 2009-02-24 CO CO09018558A patent/CO6150193A2/es unknown
-
2010
- 2010-02-10 HK HK10101487.6A patent/HK1134441A1/xx not_active IP Right Cessation
- 2010-05-20 US US12/784,309 patent/US20100285010A1/en not_active Abandoned
-
2011
- 2011-05-19 US US13/111,784 patent/US20110223159A1/en not_active Abandoned
-
2012
- 2012-08-14 US US13/585,095 patent/US20130183292A1/en not_active Abandoned
-
2013
- 2013-05-15 JP JP2013103182A patent/JP2013163687A/ja not_active Withdrawn
-
2015
- 2015-03-30 IL IL238045A patent/IL238045A0/en unknown
- 2015-05-13 US US14/711,671 patent/US20150239969A1/en not_active Abandoned
- 2015-08-14 JP JP2015160099A patent/JP2015214582A/ja not_active Ceased
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2017
- 2017-10-23 US US15/791,285 patent/US20180251536A1/en not_active Abandoned
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