CO5631429A2 - Combinacion farmaceutica - Google Patents
Combinacion farmaceuticaInfo
- Publication number
- CO5631429A2 CO5631429A2 CO04120030A CO04120030A CO5631429A2 CO 5631429 A2 CO5631429 A2 CO 5631429A2 CO 04120030 A CO04120030 A CO 04120030A CO 04120030 A CO04120030 A CO 04120030A CO 5631429 A2 CO5631429 A2 CO 5631429A2
- Authority
- CO
- Colombia
- Prior art keywords
- compound
- pharmaceutically acceptable
- pharmaceutical combination
- admixture
- diluent
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 8
- 229940126062 Compound A Drugs 0.000 abstract 2
- NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 abstract 2
- 239000000654 additive Substances 0.000 abstract 2
- 230000000996 additive effect Effects 0.000 abstract 2
- 239000013066 combination product Substances 0.000 abstract 2
- 229940127555 combination product Drugs 0.000 abstract 2
- 239000003085 diluting agent Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
1.- Un producto de combinación que comprende:(a) un compuesto de la reivindicación 1 en WO 02/44145 o su derivado farmacéuticamente aceptable; y (1) un compuesto como se define en la reivindicación 1 de WO 01/28992 ó (2) un compuesto de la Reivindicación 34 de WO 01/28992 ó (3) Compuesto A o B o C o D (o sus sales farmacéuticamente aceptables) en donde cada uno de los componentes (a) y (b) se formulan en mezcla con un aditivo, diluyente o vehículo farmacéuticamente aceptable.2.- Un producto de combinación, como se reivindica en la Reivindicación 1, que comprende una formulación farmacéutica que incluye un compuesto de la reivindicación 1 en WO 02/44145 o un compuesto de la reivindicación 20 en WO 02/44145 o sub-conjunto 1, 2 ó 3 de los compuestos de la reivindicación 20 o su derivado farmacéuticamente aceptable, y (1) un compuesto como se define en la reivindicación 1 de WO 01/28992 ó (2) un compuesto de la Reivindicación 34 de WO 01/28992 ó (3) Compuesto A o B o C o D (o sus sales farmacéuticamente aceptables) o su derivado farmacéuticamente aceptable, en mezcla con un aditivo, diluyente o vehículo farmacéuticamente aceptable.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0201662A SE0201662D0 (sv) | 2002-05-31 | 2002-05-31 | Pharmaceutical combination |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5631429A2 true CO5631429A2 (es) | 2006-04-28 |
Family
ID=20288040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO04120030A CO5631429A2 (es) | 2002-05-31 | 2004-11-29 | Combinacion farmaceutica |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20060052314A1 (es) |
| EP (1) | EP1513807A1 (es) |
| JP (1) | JP2005532345A (es) |
| CN (1) | CN1656066A (es) |
| AR (1) | AR040138A1 (es) |
| AU (1) | AU2003232711A1 (es) |
| BR (1) | BR0311138A (es) |
| CA (1) | CA2486110A1 (es) |
| CO (1) | CO5631429A2 (es) |
| IL (1) | IL165169A0 (es) |
| IS (1) | IS7581A (es) |
| MX (1) | MXPA04011910A (es) |
| NO (1) | NO20044673L (es) |
| PL (1) | PL373409A1 (es) |
| RU (1) | RU2004131868A (es) |
| SE (1) | SE0201662D0 (es) |
| TW (1) | TW200307686A (es) |
| WO (1) | WO2003101956A1 (es) |
| ZA (1) | ZA200408787B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0401539D0 (sv) | 2004-06-15 | 2004-06-15 | Astrazeneca Ab | New compounds |
| WO2006135316A1 (en) | 2005-06-13 | 2006-12-21 | Astrazeneca Ab | New oxabispidine compounds for the treatment of cardiac arrhythmias |
| WO2006137772A1 (en) * | 2005-06-20 | 2006-12-28 | Astrazeneca Ab | New physical form of n,n´- disubstituted oxabispidines |
| JP5114880B2 (ja) | 2006-07-06 | 2013-01-09 | ダイキン工業株式会社 | 新規α−フルオロメトキシカルボン酸エステル、該α−フルオロメトキシカルボン酸エステルの製造方法及びセボフルランの製造方法 |
| US9802954B2 (en) | 2011-08-24 | 2017-10-31 | Boehringer Ingelheim International Gmbh | Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma |
| CN108314624B (zh) * | 2017-01-17 | 2022-09-27 | 东莞东阳光科研发有限公司 | 一种多氟苯胺的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9903759D0 (sv) * | 1999-10-18 | 1999-10-18 | Astra Ab | Pharmaceutically active compounds |
| AR035216A1 (es) * | 2000-12-01 | 2004-05-05 | Astrazeneca Ab | Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios |
-
2002
- 2002-05-31 SE SE0201662A patent/SE0201662D0/xx unknown
-
2003
- 2003-05-16 TW TW092113322A patent/TW200307686A/zh unknown
- 2003-05-27 JP JP2004509650A patent/JP2005532345A/ja active Pending
- 2003-05-27 PL PL03373409A patent/PL373409A1/xx not_active Application Discontinuation
- 2003-05-27 CN CNA038117347A patent/CN1656066A/zh active Pending
- 2003-05-27 BR BR0311138-5A patent/BR0311138A/pt not_active IP Right Cessation
- 2003-05-27 MX MXPA04011910A patent/MXPA04011910A/es unknown
- 2003-05-27 WO PCT/SE2003/000854 patent/WO2003101956A1/en active Application Filing
- 2003-05-27 EP EP03756136A patent/EP1513807A1/en not_active Withdrawn
- 2003-05-27 US US10/516,426 patent/US20060052314A1/en not_active Abandoned
- 2003-05-27 AU AU2003232711A patent/AU2003232711A1/en not_active Abandoned
- 2003-05-27 CA CA002486110A patent/CA2486110A1/en not_active Abandoned
- 2003-05-27 RU RU2004131868/15A patent/RU2004131868A/ru not_active Application Discontinuation
- 2003-05-28 AR ARP030101881A patent/AR040138A1/es not_active Application Discontinuation
-
2004
- 2004-10-28 NO NO20044673A patent/NO20044673L/no unknown
- 2004-10-29 ZA ZA200408787A patent/ZA200408787B/xx unknown
- 2004-11-11 IL IL16516904A patent/IL165169A0/xx unknown
- 2004-11-29 CO CO04120030A patent/CO5631429A2/es not_active Application Discontinuation
- 2004-12-03 IS IS7581A patent/IS7581A/is unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003232711A1 (en) | 2003-12-19 |
| IS7581A (is) | 2004-12-03 |
| CN1656066A (zh) | 2005-08-17 |
| AR040138A1 (es) | 2005-03-16 |
| IL165169A0 (en) | 2005-12-18 |
| WO2003101956A1 (en) | 2003-12-11 |
| JP2005532345A (ja) | 2005-10-27 |
| CA2486110A1 (en) | 2003-12-11 |
| PL373409A1 (en) | 2005-08-22 |
| EP1513807A1 (en) | 2005-03-16 |
| MXPA04011910A (es) | 2005-03-31 |
| RU2004131868A (ru) | 2005-10-10 |
| NO20044673L (no) | 2004-12-07 |
| ZA200408787B (en) | 2005-10-20 |
| BR0311138A (pt) | 2005-03-01 |
| SE0201662D0 (sv) | 2002-05-31 |
| US20060052314A1 (en) | 2006-03-09 |
| TW200307686A (en) | 2003-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Application withdrawn |