CO5241360A1 - Composiciones de flint y usos de estas - Google Patents
Composiciones de flint y usos de estasInfo
- Publication number
- CO5241360A1 CO5241360A1 CO99076841A CO99076841A CO5241360A1 CO 5241360 A1 CO5241360 A1 CO 5241360A1 CO 99076841 A CO99076841 A CO 99076841A CO 99076841 A CO99076841 A CO 99076841A CO 5241360 A1 CO5241360 A1 CO 5241360A1
- Authority
- CO
- Colombia
- Prior art keywords
- replaced
- val
- gly
- leu
- ile
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4703—Regulators; Modulating activity
- G01N2333/4704—Inhibitors; Supressors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Un ácido nucleico aislado que codifica una proteína que tiene la secuencia SEC Nº ID 4. ácido nucleico aislado que codifica una proteína FLINT que tiene al menos una sustitución en la SEC Nº ID 2 seleccionada entre el grupo formado por: a) La Ser en posición 10 se sustituye de forma alternativa por Thr, Leu, Val, Ile, Gly o Ala, b) La Leu en posición 16 se sustituye de forma alternativa por Ile, Val, Ala o Gly, c) La Pro en posición 23 se sustituye de forma alternativa por Leu, lle, Val, Ala, o Gly, d) La Val en posición 27 se sustituye de forma alternativa por Gly, Ala Leu o Ile, f) La Val en posición 30 se sustituye de forma alternativa por Leu, Ile, Val, Ala o Gly, f) La Ala en posición 31 se sustituye de forma alternativa por Gly, Val, Leu o Ile,g) La Thr en posición 33 se sustituye de forma alternativa por ser, Ala, Gly, Leu, Val o lle, h) La Ala en posición 41 se sustituye de forma alternativa por Thr, Gly, Val, Leu o Ile, i) El Glu en posición 42 se sustituye de forma alternativa por Asn o Gln,j) La Arg en posición 46 se sustituye de forma alternativa por His o Lys, k) La Arg en posición 60 se sustituye de forma alternativa por His o Lys,l) La Ala en posición 104 se sustituye de forma alternativa por Gly, Val, Leu o Ile, m) La Ser en posición 131 se sustituye de forma alternativa por Thr, Ile, Leu, Ala o Gly, n) La Ala en posición 136 se sustituye de forma alternativa por Gly, Val, Leu o Ile, o) La Ile en posición 139 se sustituye de forma alternativa por Leu, Gly, Ala o Val, p) La Thr en posición 191 se sustituye de forma alternativa por Ser, Ala, Gly, Leu, Ile o Val,q) La Gly en posición 198 se sustituye de forma alternativa por Ala, Val, Ile o Leu, r) La Ala en posición 208 se sustituye de forma alternativa por Gly, Leu, Val o Ile, El Glu en posición 212 se sustituye de forma alternativa por Asp, Asn o Gln, t) La Ala en posición 238 se sustituye de forma alternativa por Gly, Leu, Val o Ile, ...
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11157598P | 1998-12-09 | 1998-12-09 | |
| US11158098P | 1998-12-09 | 1998-12-09 | |
| US11506999P | 1999-01-07 | 1999-01-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5241360A1 true CO5241360A1 (es) | 2003-01-31 |
Family
ID=27381019
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO99076841A CO5241360A1 (es) | 1998-12-09 | 1999-12-07 | Composiciones de flint y usos de estas |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1020521A1 (es) |
| AU (1) | AU2164400A (es) |
| CO (1) | CO5241360A1 (es) |
| PE (1) | PE20001388A1 (es) |
| WO (1) | WO2000034782A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7285267B2 (en) | 1997-01-14 | 2007-10-23 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6α & 6β |
| CN1247567A (zh) | 1997-01-14 | 2000-03-15 | 人体基因组科学有限公司 | 肿瘤坏死因子受体6α和6β |
| WO2000058465A2 (en) * | 1999-03-30 | 2000-10-05 | Eli Lilly And Company | Flint polypeptide analogs |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5712115A (en) * | 1996-03-19 | 1998-01-27 | Incyte Pharmaceuticals, Inc. | Human cell death-associated protein |
| CN1247567A (zh) * | 1997-01-14 | 2000-03-15 | 人体基因组科学有限公司 | 肿瘤坏死因子受体6α和6β |
| US5885800A (en) * | 1997-02-04 | 1999-03-23 | Smithkline Beecham Corporation | DNA encoding tumor necrosis related receptor, TR4 |
| AU9013998A (en) * | 1997-07-21 | 1999-02-10 | Zymogenetics Inc. | Tumor necrosis factor receptor ztnfr-5 |
-
1999
- 1999-12-07 PE PE1999001217A patent/PE20001388A1/es not_active Application Discontinuation
- 1999-12-07 AU AU21644/00A patent/AU2164400A/en not_active Abandoned
- 1999-12-07 EP EP99309823A patent/EP1020521A1/en not_active Withdrawn
- 1999-12-07 WO PCT/US1999/028696 patent/WO2000034782A1/en active Application Filing
- 1999-12-07 CO CO99076841A patent/CO5241360A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1020521A1 (en) | 2000-07-19 |
| PE20001388A1 (es) | 2000-12-15 |
| WO2000034782A1 (en) | 2000-06-15 |
| AU2164400A (en) | 2000-06-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Application withdrawn |