CO4990949A1 - Derivados de imidazol y su preparacion . - Google Patents
Derivados de imidazol y su preparacion .Info
- Publication number
- CO4990949A1 CO4990949A1 CO98067821A CO98067821A CO4990949A1 CO 4990949 A1 CO4990949 A1 CO 4990949A1 CO 98067821 A CO98067821 A CO 98067821A CO 98067821 A CO98067821 A CO 98067821A CO 4990949 A1 CO4990949 A1 CO 4990949A1
- Authority
- CO
- Colombia
- Prior art keywords
- pyridine
- phenyl
- hydroxy
- group
- represent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Compuesto de fórmula (I)en la cual:A representa un heterociclo, saturado o insaturado, que comprende un átomo de nitrógeno de fórmula (B), (D), (E) o (F): R1 y R2 representan, independientemente uno de otro, un hidrógeno un grupo C1-6 alquilo, o forman juntos un grupo polimetileno -(CH2 )n -, pudiendo n tomar los valores de 3 a 6, R5 representa un fenilo o una 2-, 3- o 4-piridina, siendo el fenilo o la piridina sustituido por R3 y R´3 , donde R3 y R´3 representan, independientemente uno de otro, un átomo de hidrógeno, de halógeno, un hidroxi, un grupoC1-4 alquilo o C1-6 alcoxi, R6 representa un fenilo o una 2-, 3- o 4-piridina, siendo el fenilo o la piridina sustituido por R4 y R´4 , donde R4 y R´4 representan, independientemente uno de otro, un átomo de hidrógeno, un halógeno, un hidroxi, un amino, un ciano, una sulfonamida, un aminocarbonilo, un trifluorometilo, un grupo C1-6 alcoxi, (di)hidroxi-C1-6 alcoxi o C1-4 alquilo, y R7 representa un átomo de hidrógeno o un grupo C1-2 alquilo, en forma de enantiómero, de diastereoisómero o de mezcla de estas diferentes formas, incluida la mezcla racémica así como sus derivados N-óxido y sus sales de adición a ácidos farmacéuticamente aceptables.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9714486A FR2771093B1 (fr) | 1997-11-19 | 1997-11-19 | Derives d'imidazole, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4990949A1 true CO4990949A1 (es) | 2000-12-26 |
Family
ID=9513524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO98067821A CO4990949A1 (es) | 1997-11-19 | 1998-11-18 | Derivados de imidazol y su preparacion . |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6200991B1 (es) |
| EP (1) | EP1032569A1 (es) |
| JP (1) | JP2001523679A (es) |
| AR (1) | AR023292A1 (es) |
| AU (1) | AU1243399A (es) |
| CO (1) | CO4990949A1 (es) |
| FR (1) | FR2771093B1 (es) |
| TW (1) | TW448170B (es) |
| WO (1) | WO1999025710A1 (es) |
| ZA (1) | ZA9810558B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2805815B1 (fr) * | 2000-03-01 | 2002-05-17 | Sanofi Synthelabo | Derives de polyfluoroalkylimidazole, leur preparation et leur application en therapeutique |
| FR2805816B1 (fr) * | 2000-03-01 | 2002-05-17 | Sanofi Synthelabo | Derives d'haloimidazole, leur preparation et leur application en therapeutique |
| JP2004511548A (ja) * | 2000-10-16 | 2004-04-15 | 中外製薬株式会社 | Ｎ−置換された２−スルファニルイミダゾールの調製方法 |
| JP4653935B2 (ja) * | 2001-03-29 | 2011-03-16 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | ヒスタミンｈ３受容体のリガンドとして用いるに有用なイミダゾリル誘導体 |
| EP1480631B1 (en) * | 2002-12-20 | 2007-08-01 | Dynogen Pharmaceuticals Inc. | Methods of treating non-painful bladder disorders using alpha2-delta- subunit calcium channel modulators |
| WO2004084879A1 (en) * | 2003-03-21 | 2004-10-07 | Dynogen Pharmaceuticals, Inc. | Methods for treating lower urinary tract disorders using smooth muscle modulators and alpha-2-delta subunit calcium channel modulators |
| US20100222393A1 (en) | 2005-12-30 | 2010-09-02 | Naresh Kumar | Muscarinic receptor antagonists |
| US20090156465A1 (en) * | 2005-12-30 | 2009-06-18 | Sattigeri Jitendra A | Derivatives of beta-amino acid as dipeptidyl peptidase-iv inhibitors |
| EP2076261A2 (en) * | 2006-10-03 | 2009-07-08 | Ranbaxy Laboratories, Ltd. | Muscarinic receptor antagonists |
| EP2129663A2 (en) * | 2007-02-28 | 2009-12-09 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
| US20090326004A1 (en) | 2008-06-03 | 2009-12-31 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ223654A (en) * | 1987-03-09 | 1990-03-27 | Janssen Pharmaceutica Nv | 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions |
| US5169855A (en) * | 1990-03-28 | 1992-12-08 | Du Pont Merck Pharmaceutical Company | Piperidine ether derivatives as psychotropic drugs or plant fungicides |
| FR2747678B1 (fr) | 1996-04-22 | 1998-05-22 | Synthelabo | Composes derives d'imidazobenzoxazine, leurs procedes de preparation et leurs utilisations en therapeutique |
| FR2751647B1 (fr) | 1996-07-25 | 1998-09-11 | Synthelabo | Derives de benzimidazole, leurs preparations et leurs applications en therapeutique |
-
1997
- 1997-11-19 FR FR9714486A patent/FR2771093B1/fr not_active Expired - Fee Related
-
1998
- 1998-11-17 US US09/554,138 patent/US6200991B1/en not_active Expired - Fee Related
- 1998-11-17 WO PCT/FR1998/002446 patent/WO1999025710A1/fr not_active Application Discontinuation
- 1998-11-17 EP EP98955672A patent/EP1032569A1/fr not_active Withdrawn
- 1998-11-17 JP JP2000521093A patent/JP2001523679A/ja not_active Withdrawn
- 1998-11-17 AU AU12433/99A patent/AU1243399A/en not_active Abandoned
- 1998-11-18 CO CO98067821A patent/CO4990949A1/es unknown
- 1998-11-18 ZA ZA9810558A patent/ZA9810558B/xx unknown
- 1998-11-18 TW TW087119098A patent/TW448170B/zh not_active IP Right Cessation
- 1998-11-18 AR ARP980105841A patent/AR023292A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA9810558B (en) | 1999-05-18 |
| FR2771093B1 (fr) | 2000-01-21 |
| US6200991B1 (en) | 2001-03-13 |
| AU1243399A (en) | 1999-06-07 |
| TW448170B (en) | 2001-08-01 |
| FR2771093A1 (fr) | 1999-05-21 |
| AR023292A1 (es) | 2002-09-04 |
| EP1032569A1 (fr) | 2000-09-06 |
| WO1999025710A1 (fr) | 1999-05-27 |
| JP2001523679A (ja) | 2001-11-27 |
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