[go: up one dir, main page]

CO4970832A1 - NEW FORMULATIONS AND PROCESSES FOR ITS MANUFACTURE - Google Patents

NEW FORMULATIONS AND PROCESSES FOR ITS MANUFACTURE

Info

Publication number
CO4970832A1
CO4970832A1 CO98068459A CO98068459A CO4970832A1 CO 4970832 A1 CO4970832 A1 CO 4970832A1 CO 98068459 A CO98068459 A CO 98068459A CO 98068459 A CO98068459 A CO 98068459A CO 4970832 A1 CO4970832 A1 CO 4970832A1
Authority
CO
Colombia
Prior art keywords
manufacture
processes
paroxetine
new formulations
solution
Prior art date
Application number
CO98068459A
Other languages
Spanish (es)
Inventor
Ahmad Ghazawi
Stanley Leonard Graham
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of CO4970832A1 publication Critical patent/CO4970832A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Una cápsula oral tragable, que contiene paroxetina disuelta en un vehículo. Una cápsula oral tragable, que comprende una cubierta de cápsula que contiene paroxetina como la base libre o una sal o solvato farmacéuticamente aceptable de la misma, en disolución en un vehículo líquido o sólido. 1Una formulación farmacéutica, que comprende una disolución de paroxetina en una mezcla de un agente solubilizante y un lípido y/o aceite.A swallowable oral capsule, containing paroxetine dissolved in a vehicle. A swallowable oral capsule, comprising a capsule shell containing paroxetine as the free base or a pharmaceutically acceptable salt or solvate thereof, in solution in a liquid or solid vehicle. 1A pharmaceutical formulation, comprising a solution of paroxetine in a mixture of a solubilizing agent and a lipid and / or oil.

CO98068459A 1997-11-21 1998-11-20 NEW FORMULATIONS AND PROCESSES FOR ITS MANUFACTURE CO4970832A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9724544.3A GB9724544D0 (en) 1997-11-21 1997-11-21 Novel Formulation

Publications (1)

Publication Number Publication Date
CO4970832A1 true CO4970832A1 (en) 2000-11-07

Family

ID=10822374

Family Applications (1)

Application Number Title Priority Date Filing Date
CO98068459A CO4970832A1 (en) 1997-11-21 1998-11-20 NEW FORMULATIONS AND PROCESSES FOR ITS MANUFACTURE

Country Status (24)

Country Link
EP (1) EP1033986A1 (en)
JP (1) JP2001523718A (en)
KR (1) KR20010032320A (en)
CN (1) CN1279608A (en)
AP (1) AP2000001821A0 (en)
AR (1) AR015485A1 (en)
AU (1) AU1168099A (en)
BG (1) BG104527A (en)
BR (1) BR9814220A (en)
CO (1) CO4970832A1 (en)
DZ (1) DZ2658A1 (en)
EA (1) EA200000552A1 (en)
GB (1) GB9724544D0 (en)
HU (1) HUP0100580A3 (en)
IL (1) IL136106A0 (en)
MA (1) MA24704A1 (en)
NO (1) NO20002590L (en)
OA (1) OA11385A (en)
PE (1) PE20000381A1 (en)
PL (1) PL340555A1 (en)
SK (1) SK7342000A3 (en)
TR (1) TR200001423T2 (en)
WO (1) WO1999026625A1 (en)
ZA (1) ZA9810637B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9810180D0 (en) * 1998-05-13 1998-07-08 Smithkline Beecham Plc Novel formulation
DE50011819D1 (en) * 1999-03-12 2006-01-12 Aesica Pharmaceuticals Ltd STABLE PHARMACEUTICAL APPLICATION FOR PAROXETIN ANHYDRATE
DE60004768T2 (en) 1999-07-01 2004-07-08 Italfarmaco S.P.A. COMPLEXES OF PAROXETINE WITH CYCLODEXTRIN OR CYCLODEXTRIN DERIVATIVES
DE19930454A1 (en) * 1999-07-02 2001-01-04 Knoll Ag Solid paroxetine-containing preparations
US6720003B2 (en) 2001-02-16 2004-04-13 Andrx Corporation Serotonin reuptake inhibitor formulations
DE60222803T2 (en) * 2001-12-21 2008-07-17 Supernus Pharmaceuticals, Inc. ORAL CAPSULE FORMULATION WITH IMPROVED PHYSICAL STABILITY
SE0200475D0 (en) * 2002-02-15 2002-02-15 Ltp Lipid Technologies Provide Oral pharmaceutical preparation
WO2006119779A2 (en) * 2005-05-10 2006-11-16 Lifecycle Pharma A/S A pharmaceutical composition comprising an aldosterone antagonist in form of solid solution
US20120322752A1 (en) * 2009-12-08 2012-12-20 Sung Kyun Lee SOLID DISPERSIONS CONTAINING 20-O-beta-D-GLUCOPYRANOSYL-20(S)-PROTOPANAXADIOL
GB201020032D0 (en) * 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
CN103961333B (en) * 2014-05-07 2020-02-21 浙江华海药业股份有限公司 Paroxetine mesylate capsule and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3768536B2 (en) * 1995-04-03 2006-04-19 アボツト・ラボラトリーズ Homogeneous mixture of low-melting drugs and additives for controlled release
BR9806754A (en) * 1997-01-15 2000-03-14 Smithkline Beecham Plc Paroxetine compositions.

Also Published As

Publication number Publication date
NO20002590D0 (en) 2000-05-19
SK7342000A3 (en) 2000-12-11
MA24704A1 (en) 1999-07-01
EA200000552A1 (en) 2000-10-30
AR015485A1 (en) 2001-05-02
PE20000381A1 (en) 2000-05-07
NO20002590L (en) 2000-07-19
HUP0100580A3 (en) 2002-05-28
ZA9810637B (en) 2000-05-22
CN1279608A (en) 2001-01-10
IL136106A0 (en) 2001-05-20
BG104527A (en) 2001-04-30
BR9814220A (en) 2001-12-26
EP1033986A1 (en) 2000-09-13
AP2000001821A0 (en) 2000-06-30
GB9724544D0 (en) 1998-01-21
AU1168099A (en) 1999-06-15
OA11385A (en) 2004-01-27
KR20010032320A (en) 2001-04-16
DZ2658A1 (en) 2003-03-22
JP2001523718A (en) 2001-11-27
WO1999026625A1 (en) 1999-06-03
TR200001423T2 (en) 2000-10-23
PL340555A1 (en) 2001-02-12
HUP0100580A2 (en) 2002-04-29

Similar Documents

Publication Publication Date Title
ES2178430T3 (en) USE OF GELIFICABLE PHARMACEUTICAL COMPOSITIONS IN PARODONTOLOGY.
AR017512A1 (en) TABLETS OF QUICKLY DISPOSABLE METILCELLULOSE FOR ORAL ROUTE ADMINISTRATION AND PROCEDURE TO PREPARE THEM
UY26372A1 (en) "IMIDAZO-3-IL-AMINAS BICÍCLICAS PROCEDURE FOR ITS PREPARATION AND DRUGS THAT CONTAIN THEM"
AR037490A1 (en) SOLID PHARMACEUTICAL COMPOSITIONS, PROCESS FOR PREPARATION, KIT FOR THE TREATMENT OF OBESITY AND USE OF SUCH COMPOSITIONS IN THE DEVELOPMENT OF MEDICINES
ES2190075T3 (en) SOLID PHARMACEUTICAL FORMULATIONS CONTAINING A PHYSICAL MIXTURE OF SULFOALQUIL-ETER-CYCLODEXTRINE AND A THERAPEUTIC AGENT.
ES2110377T1 (en) GALLENIC FORMULATION OF PHENOFIBRATE AND APPLICATION OF THE SAME.
KR950031069A (en) How to suppress bone loss and lower serum cholesterol
ATE554750T1 (en) PREPARATIONS CONTAINING HYDROPHOBIC PHARMACEUTICAL ACTIVE INGREDIENTS
AU2001283563A1 (en) Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent
CO5271759A1 (en) FORMULATION IN SOLUTION CONTAINING A MIXTURE OF SOLVENTS
ATE65023T1 (en) PHARMACEUTICAL AGENT.
ES2113444T3 (en) MEDICINES.
EP1033981A4 (en) Formulations and methods for reducing toxicity of antineoplastic agents
BR0215184A (en) orally active taxane derivative pharmaceutical compositions having increased bioavailability
ES2126766T3 (en) TROPYL 7-AZAINDOL-3-ILCARBOXIAMIDES AS ANTI-TUSSIVE AGENT.
ATE224717T1 (en) ORAL MEDICINAL PREPARATIONS CONTAINING A BENZHYDRYLPIPERAZINE AND A CYCLODEXTRIN
BR9714310A (en) Pharmaceutical composition
ES2145158T3 (en) NEW FORMULATION OF EMULSION.
AR013710A1 (en) ORAL CYCLOSPORINE FORMULATIONS
EP1365749A4 (en) PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR USE WITH SOFT GELATINE FORMULATIONS
FI932553A7 (en) New pharmaceutical formulations containing a pharmacologically active ionizable substance and a method for their preparation
CO4970832A1 (en) NEW FORMULATIONS AND PROCESSES FOR ITS MANUFACTURE
AR011919A1 (en) FORMULATION IN TABLETS OR SWALLOWING CAPSULES OF PARACETAMOL (N-ACETIL-P-AMINOFENOL) AND PROCEDURE TO PREPARE IT
HUP9701111A2 (en) Fill material for soft gelatinous pharmaceutical dosage form
ES2149979T3 (en) STABILIZED COMPOSITION FOR THE ORAL ADMINISTRATION OF PEPTIDES.