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CO2025003422A2 - Composiciones de célula de rescate fotorreceptora (prc) y métodos para el tratamiento de trastornos oculares - Google Patents

Composiciones de célula de rescate fotorreceptora (prc) y métodos para el tratamiento de trastornos oculares

Info

Publication number
CO2025003422A2
CO2025003422A2 CONC2025/0003422A CO2025003422A CO2025003422A2 CO 2025003422 A2 CO2025003422 A2 CO 2025003422A2 CO 2025003422 A CO2025003422 A CO 2025003422A CO 2025003422 A2 CO2025003422 A2 CO 2025003422A2
Authority
CO
Colombia
Prior art keywords
prc
treatment
methods
rescue cell
ocular disorders
Prior art date
Application number
CONC2025/0003422A
Other languages
English (en)
Inventor
Samantha Jean Paulsen
Masashi Abe
Dang Quy Dao
Daniel James Hiler
Erin Kimbrel
Chenmei Luo
Dmitriy I Podolskiy
Ramirez Santiago Reyes
Kraig Marc Theriault
Rebecca Eunkyung Jo
Original Assignee
Astellas Inst For Regenerative Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Inst For Regenerative Medicine filed Critical Astellas Inst For Regenerative Medicine
Publication of CO2025003422A2 publication Critical patent/CO2025003422A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/062—Sensory transducers, e.g. photoreceptors; Sensory neurons, e.g. for hearing, taste, smell, pH, touch, temperature, pain

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invención proporciona poblaciones de células de rescate fotorreceptoras (PRC) que poseen perfiles de marcadores únicos y generadas por diferenciación in vitro de progenitores anteriores que incluyen células madre pluripotentes y células madre embrionarias (ESC). También se proporcionan métodos para generar poblaciones de células de rescate fotorreceptoras y utilizarlas para el tratamiento de trastornos oculares.
CONC2025/0003422A 2022-08-23 2025-03-17 Composiciones de célula de rescate fotorreceptora (prc) y métodos para el tratamiento de trastornos oculares CO2025003422A2 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263373298P 2022-08-23 2022-08-23
US202263432948P 2022-12-15 2022-12-15
PCT/US2023/030699 WO2024044134A1 (en) 2022-08-23 2023-08-21 Photoreceptor rescue cell (prc) compositions and methods for treatment of ocular disorders

Publications (1)

Publication Number Publication Date
CO2025003422A2 true CO2025003422A2 (es) 2025-03-27

Family

ID=88018057

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2025/0003422A CO2025003422A2 (es) 2022-08-23 2025-03-17 Composiciones de célula de rescate fotorreceptora (prc) y métodos para el tratamiento de trastornos oculares

Country Status (5)

Country Link
AU (1) AU2023330893A1 (es)
CO (1) CO2025003422A2 (es)
IL (1) IL318429A (es)
TW (1) TW202417614A (es)
WO (1) WO2024044134A1 (es)

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US7410773B2 (en) 1995-02-02 2008-08-12 Ghazi Jaswinder Dhoot Method of preparing an undifferentiated cell
US7410798B2 (en) 2001-01-10 2008-08-12 Geron Corporation Culture system for rapid expansion of human embryonic stem cells
JP4498614B2 (ja) 1998-12-07 2010-07-07 デューク ユニバーシティ 幹細胞の単離方法
AUPQ147799A0 (en) 1999-07-07 1999-07-29 Medvet Science Pty. Ltd. Mesenchymal precursor cell
US7015037B1 (en) 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
US7422736B2 (en) 2002-07-26 2008-09-09 Food Industry Research And Development Institute Somatic pluripotent cells
US20140134195A1 (en) 2011-04-20 2014-05-15 University Of Washington Through Its Center For Commercialization Beta-2 microglobulin-deficient cells
EP3824910A1 (en) * 2011-05-18 2021-05-26 The Regents of The University of California Compositions and methods for treating retinal diseases
DK2838548T5 (en) 2012-04-17 2024-08-05 Univ Washington Through Its Center For Commercialization Hla class ii deficient cells, hla class i deficient cells capable of expressing hla class ii proteins, and uses thereof
US20130273544A1 (en) 2012-04-17 2013-10-17 Life Technologies Corporation Methods and compositions for exosome isolation
US9005888B2 (en) 2012-06-14 2015-04-14 System Biosciences, Llc Methods for microvesicle isolation and selective removal
BR112018003031B1 (pt) 2015-08-18 2023-12-26 Astellas Institute For Regenerative Medicine Solução salina de vida útil prolongada, preparação celular, seus usos, método de obtenção e armazenamento de preparação celular, composição farmacêutica e kit
WO2017176810A1 (en) * 2016-04-04 2017-10-12 Biotime, Inc. Pluripotent stem cell-derived 3d retinal tissue and uses thereof
EP3992280A1 (en) * 2020-10-30 2022-05-04 Kugelmeiers Ltd. Method for the generation of neurospheres
EP4274421A4 (en) * 2021-01-07 2025-03-26 Memorial Sloan Kettering Cancer Center METHODS FOR GENERATING CORTICAL EXCITATORY NEURONS

Also Published As

Publication number Publication date
WO2024044134A1 (en) 2024-02-29
AU2023330893A1 (en) 2025-01-30
IL318429A (en) 2025-03-01
TW202417614A (zh) 2024-05-01

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