CN222585248U - Reservoir type multi-dose dry powder inhaler - Google Patents

Abstract

The utility model relates to a reservoir type multi-dose dry powder inhaler, belonging to the field of powder inhalation administration. Comprises a main body, an airflow indicating assembly and a counting assembly. The medicine bin is used for uniformly accommodating multiple doses of medicine powder, the main body is located on the peripheral surface of the medicine bin and is provided with a set air inlet channel, the air inlet channel comprises a vertical indication channel, the indication channel can be used for enabling the indication pellets to move up and down freely along a straight line path, in the using process of a patient, the air suction action drives the indication pellets to change in position in the indication channel, and the patient can obtain real-time feedback on whether the inhalation action reaches the standard or not, so that the subsequent inhalation force is adjusted, and the best medicine administration effect is ensured.

Description

Reservoir type multi-dose dry powder inhaler

Technical Field

The present utility model relates to a dry powder inhaler for pharmaceutical use, and more particularly, to a reservoir type dry powder inhaler for storing multiple doses of medicinal powder using a cartridge.

Background

The dry powder inhaler and the inhalation aerosol are both portable inhalation administration treatment means, wherein the administration mode of the dry powder inhaler is active inhalation of a patient, so that the dry powder inhaler has better patient compliance, and compared with the inhalation aerosol, the dry powder inhaler needs to be added with a propellant as a driving means, and is more friendly to the environment. The main dry powder inhalers are classified into capsule type, blister type and reservoir type.

The existing reservoir type dry powder drug administration device on the market is configured with a counting mode taking 10 as a unit, namely, one transition of a corresponding counting wheel disc is used every ten times, and the method can not achieve fine indication although the fuzzy prediction of the residual powder quantity in the device by a patient is met, and the digital display is smaller. When the remaining powder dose in the inhaler device is less than 10, there may occur a possibility that the patient may not be ready for a new dry powder inhaler device in time due to erroneous judgment of the indication.

The dry powder inhaler takes active inhalation of a patient as a driving mode, so that the use of the device has requirements on the inhalation force of the patient, and when the inhalation force of the patient is smaller, the powder can stay in the oral cavity or the throat of the patient, so that the administration effect of the powder entering the lung is affected. Meanwhile, the medicine powder state also affects the medicine feeding effect, and when the medicine powder is agglomerated, a patient needs to shake the device before using the medicine powder, so that the medicine powder in the medicine powder dispersing device is uniformly dispersed. The existing reservoir type dry powder inhaler on the market adopts a non-transparent shell, which causes that a patient is difficult to judge whether the powder in the device is in a uniformly dispersed state or not, whether the powder in a single dose is completely inhaled or not, and the subsequent inhalation force is difficult to adjust according to real-time feedback.

Disclosure of utility model

The main object of the present utility model is to solve the above problems and to provide a reservoir type multi-dose dry powder inhaler which is more accurate in counting and gives real-time feedback to the patient during inhalation administration.

A reservoir type multi-dose dry powder inhaler comprising a mouthpiece cover, a mouthpiece, an airflow indicating assembly, an outer cover, a spring, a cartridge cover, a body, a dispenser, and a counting assembly, wherein:

The medicine bin is used for uniformly accommodating multiple doses of medicine powder, a non-closed cylindrical empty slot is connected below the medicine bin and used for accommodating the medicine distributor, and a channel matched with the suction nozzle is arranged on the non-closed cylindrical empty slot along the horizontal direction of the main body;

The medicine bin cover is connected with the medicine bin and is used for sealing the medicine powder stored in the medicine bin;

The two ends of the medicine distributor are provided with operation ratchet wheels, the outer cover is provided with a transmission arm, and the transmission arm is meshed with the operation ratchet wheels;

One end of the spring is connected with the medicine bin cover, and the other end of the spring is contacted with the inner part of the outer cover to give the outer cover resilience force opposite to the pressing direction;

The airflow indicating assembly comprises an indicating small ball and an indicating cover plate;

the counting assembly comprises a high-order counting wheel disc and a low-order counting wheel disc;

the suction nozzle can enclose the main body, the airflow indicating assembly, the medicine distributor and the counting assembly, a counting window is arranged on the plane of the suction nozzle closest to the counting assembly, and partial end surfaces of the high-position counting wheel disc and the low-position counting wheel disc can be seen through the counting window;

Further, the main body is provided with a predetermined air inlet channel on the peripheral surface of the medicine bin, the air inlet channel comprises a vertical indication channel, the indication channel can allow the indication pellets to move up and down along a straight line path, and the outer cover is provided with an indication display window through which the position change of the indication pellets can be observed.

Preferably, the indicator pellets are made of a stainless steel material selected from the group consisting of the series of stainless steels commonly referred to as 304, which meets the national standard of 06Cr19Ni10 or other national equivalents, and the series of stainless steels commonly referred to as 316, which meets the national standard of 0Cr17Ni12Mo2 or other national equivalents.

Preferably, the indicating pellet may be made of an aluminum alloy material.

Preferably, the indication ball may be made of a polymeric resin material.

Preferably, the indicator pellets may be coated with a coating material such as Polytetrafluoroethylene (PTFE) or polyester resin (PET), etc.

Preferably, in the case that the integral dry powder inhaler is not pressed, that is, the spring is not contracted by an external force, the indication display window corresponds to an upper section of the indication channel.

Preferably, the indicating cover plate is made of transparent materials, and an opaque indicator is arranged at the position of the indicating cover plate corresponding to the upper section of the indicating channel.

Further, the main body part is made of transparent materials.

Further, during the use of the patient, the indicator ball is pushed by the flow of the inhalation air flow, the indicator ball corresponds to the intensity of the inhalation air flow at different positions in the indicator channel, and when the indicator ball is pushed to the indicator or higher than the indicator position, the inhalation air flow reaches the preset standard, so that the optimal effect of administration can be ensured.

Further, a group of numbers 0-9 which are sequentially arranged are arranged on the periphery of one end face of the low-level counting wheel disc, the center of the low-level counting wheel disc is a hollow hole, the hollow hole is polygonal, and a carry bulge is arranged on the periphery of the other end of the low-level counting wheel disc.

Further, a group of numbers 0-N which are sequentially arranged are arranged on the periphery of one end face of the high-order counting wheel disc, N is a number larger than 1, the other end face of the high-order counting wheel disc is of a gear structure which can be meshed with the carry bulge on the low-order counting wheel disc, and the other end face of the high-order counting wheel disc is provided with a counting termination bulge.

Preferably, the low-order counting wheel disc is coaxially arranged with the medicine distributor.

Further, the whole cylindrical structure that is of medicine distributor, evenly distributed is a plurality of ration cave on its curved surface, and is single the ration cave can hold single powder dose, one of them end of medicine distributor is the enclosed construction, is provided with the polygon projection, the projection can with the centre hollow hole of low-order count rim plate cooperatees, the medicine distributor other end is provided with sealed recess.

Preferably, a sealing convex ring is arranged in the hollow groove position for accommodating the medicine dispenser in the main body, the position of the sealing convex ring corresponds to the sealing groove, and the sealing convex ring and the sealing groove are tightly matched.

Compared with the prior art, the utility model has the following beneficial effects:

1. The counting function is completed by adopting the double gears, so that the counting result is refined, the number displayed in the counting window jumps once along with each device use action, the counting unit is accurate to 1, the patient can be helped to perfect a medication plan, a new device is prepared in time, and the delay of medication caused by the estimated error of the medicine powder dosage in the device is avoided.

2. The airflow indicating assembly is added in the device to visualize the inhalation action of the patient, when the indicating pellets in the airflow indicating assembly do not reach the position of the indicating mark, the inhalation force of the patient at the moment is not up to the standard, and the subsequent inhalation force is required to be increased, so that the medicine powder can enter the lung of the patient along with inhalation, and the best inhalation effect of each time is ensured.

3. The device main body is made of transparent materials, the suction nozzle is designed into a four-sided structure, the back plate of the main body is left, the patient can directly observe the approximate residual dosage of the medicine powder in the medicine bin and the state of the medicine powder through the back surface of the device, and the patient is prompted whether the medicine powder in the device is uniformly shaken before the device is used for sucking the medicine powder.

Drawings

The foregoing and/or additional aspects and advantages of the present utility model will become apparent and may be readily appreciated from the following description of the embodiments, taken in conjunction with the accompanying drawings, in which:

FIG. 1 is an exploded view of the structure of a reservoir type multi-dose dry powder inhaler according to a preferred embodiment of the present utility model;

FIG. 2 is a schematic view of a dispenser according to a preferred embodiment of the utility model;

FIG. 3 is a front cross-sectional view of the mating portion of the dispenser and body according to a preferred embodiment of the utility model;

FIG. 4 is a partial cross-sectional view of a counting assembly of a reservoir type multi-dose dry powder inhaler according to a preferred embodiment of the present utility model;

FIG. 5 is a schematic diagram of a counting assembly according to a preferred embodiment of the utility model;

FIG. 6 is a left side view of the dispenser mated with the body in accordance with a preferred embodiment of the utility model;

FIG. 7 is a schematic flow diagram of a reservoir type multi-dose dry powder inhaler according to a preferred embodiment of the present utility model;

FIG. 8 is a front view of the airflow indicating assembly mated with the main body in accordance with a preferred embodiment of the utility model;

FIG. 9 is a front view of a reservoir-type multi-dose dry powder inhaler with the mouthpiece and mouthpiece cover removed, in accordance with a preferred embodiment of the present utility model;

FIG. 10 is a side cross-sectional view of a reservoir type multi-dose dry powder inhaler according to a preferred embodiment of the present utility model;

FIG. 11 is a side view of a semi-open state of a reservoir type multi-dose dry powder inhaler according to a preferred embodiment of the present utility model;

The medicine box comprises a 1-suction nozzle cover, a 2-suction nozzle, a 3-airflow indicating component, a 4-outer cover, a 5-spring, a 6-medicine box cover, a 7-main body, an 8-medicine distributor, a 9-counting component, an 11-stop arm, a 21-indication window, a 22-air outlet flow channel, a 31-indication ball, a 32-indication cover plate, a 321-indication mark, a 41-transmission arm, a 42-indication display window, a 71-high-position counting wheel disc stop block, a 72-indication channel, a 73-air inlet, a 74-air inlet flow channel, a 75-air outlet, a 76-high-position counting wheel disc anti-reversion block, a 77-medicine distributor anti-reversion arm, a 78-medicine box, a 79-sealing convex ring, an 81-operation ratchet wheel, an 82-medicine distributor anti-reversion wheel, an 83-quantitative hole, an 84-convex column, an 85-sealing groove, a 91-high-position counting wheel disc, a 911-counting stop bulge, a 92-low-position counting wheel disc and a 921-carry bulge.

Detailed Description

The following description is presented to enable one of ordinary skill in the art to make and use the utility model. The preferred embodiments in the following description are by way of example only and other obvious variations will occur to those skilled in the art.

Figures 1 to 11 show a preferred embodiment of such a reservoir type multi-dose dry powder inhaler of the present utility model comprising a mouthpiece cover 1, a mouthpiece 2, an airflow indicating assembly 3, an outer cover 4, a spring 5, a cartridge cover 6, a body 7, a dispenser 8 and a counting assembly 9. Wherein:

The mouthpiece cover 1 is used to cover the part of the mouthpiece 2 that enters the patient's mouth when the device is not in use, ensuring that the part of the mouthpiece 2 that enters the patient's mouth is not contaminated during the time that it is not in use. The suction nozzle 2 is of a four-sided structure, and the back plate of the main body 7 is left in the air, so that a patient can directly observe the approximate residual dosage of the medicine powder in the medicine bin and the state of the medicine powder through the back of the device, and prompt the patient whether the medicine powder in the device is uniformly shaken before the patient inhales the medicine powder by using the device. The main body 7 is provided with a medicine bin 78, and a plurality of doses of medicine powder can be uniformly stored in the medicine bin 78. The medicine compartment cover 6 is used for being connected to the upper opening of the medicine compartment 78 to play a role in sealing. The spring 5 is fixed between the medicine compartment cover 6 and the outer cover 4 for giving the outer cover 4a resilience force opposite to the pressing direction after the pressing operation of the device is completed by the patient, and returning the outer cover 4 to the original position. The air flow indicating assembly 3 comprises an indicating ball 31 and an indicating cover plate 32, and the counting assembly 9 comprises a high counting wheel 91 and a low counting wheel 92.

As shown in fig. 2-3, the whole of the medicine dispenser 8 is in a cylindrical structure, a plurality of recessed quantitative cavities 83 are uniformly distributed on a curved surface of the medicine dispenser, and the medicine powder amount which can be contained in each quantitative cavity 83 is fixed as the dose for single inhalation administration. The two ends of the medicine distributor 8 are provided with running ratchets 81, and the gears of the running ratchets 81 at the two ends are completely identical in distribution. One end of the medicine distributor 8 is a closed structure, and a polygonal convex column 84 is arranged on the end face of the closed structure. The other end curved surface of the medicine distributor 8 is provided with a medicine distributor anti-reversion wheel 82 and a sealing groove 8, wherein the medicine distributor anti-reversion wheel 82 and a gear of the running ratchet 81 are distributed in a dislocation way.

A sealing collar 79 is provided in the body 7 below the cartridge 78 in the position of the recess for receiving the dispenser 8. When the medicine distributor 8 is installed, a quantitative hole 83 arranged on the curved surface of the medicine distributor 8 is located right below the outlet of the medicine bin 78, the positions of the sealing convex rings 79 correspond to the positions of the sealing grooves 85, and the sealing convex rings and the sealing grooves are tightly matched, so that the sealing performance of the quantitative hole 83 in the using process is guaranteed, the function of fixing the medicine distributor 8 is also achieved, the left-right deviation of the medicine distributor 8 due to shaking, moving and other actions is avoided, and the position of the quantitative hole 83 is always located right below the outlet of the medicine bin 78.

As shown in fig. 4-6, the front end of the outer cap 4 extends downwards to form two transmission arms 41, the bottom ends of the two transmission arms 41 respectively correspond to the positions of the operation ratchet wheels 81 at the two ends of the medicine dispenser 8, and the medicine dispenser 8 is pressed by the outer cap 4 to rotate through the transmission arms 41. The surface of the main body 7 for connecting with the counting assembly 9 is provided with a high-order counting wheel stop block 71 and a high-order counting wheel anti-reversion block 76. The main body 7 is used for accommodating the medicine dispenser 8, the medicine dispenser anti-reversion arm 77 is arranged inside the position, the medicine dispenser anti-reversion arm 77 is of a flexible structure, the position of the medicine dispenser anti-reversion arm corresponds to the position of the medicine dispenser anti-reversion wheel 82 on the medicine dispenser 8, and the medicine dispenser anti-reversion arm can be meshed with a ratchet wheel of the medicine dispenser anti-reversion wheel 82 to prevent the medicine dispenser 8 from rotating in the reverse direction.

The circumference of one end face of the low-level counting wheel disc 92 is provided with a group of numbers 0-9 which are sequentially and uniformly arranged, the center of the low-level counting wheel disc 92 is provided with a hollow hole, and the hollow hole is polygonal and can be tightly connected with a polygonal convex column 84 arranged on the medicine dispenser 8, so that the low-level counting wheel disc 92 and the medicine dispenser 8 can synchronously rotate. The other end periphery of the lower counting wheel 92 is provided with a carry protrusion 921 which takes the shape of a single tooth.

The circumference of one end face of the high counting wheel 91 is provided with a group of numbers 0-20 which are sequentially arranged, and the other end is provided with a gear structure which can be meshed with the carry protrusion 921. When the low counting wheel 92 rotates once, the carry protrusion 921 contacts the gear portion of the high counting wheel 91 once, and drives the high counting wheel to rotate once. The inside of the gear is provided with a counting termination protrusion 911, and when the high-order counting wheel disc 91 rotates for one circle, the counting termination protrusion 911 contacts with the high-order counting wheel disc termination block, so that the high-order counting wheel disc 91 is prevented from rotating more than a set number of times. Meanwhile, the gear part of the high-order counting wheel disc 91 is contacted with the high-order counting wheel disc anti-reversion block 76, so that dislocation offset of the high-order counting wheel disc 91 caused by shaking, moving and other actions in the daily use process of the device is avoided, and the counting accuracy of the device is ensured.

As shown in fig. 7-9, the main body 7 is provided with a predetermined air inlet channel 74 on the peripheral plane of the medicine compartment 78, and the air inlet channel 94 includes a vertical indication channel 72, and the indication channel 72 can freely move up and down along a straight path by the indication ball 31 in the air flow indication assembly 3. When the patient inhales by using the device, air flows into the air inlet channel 74 from the air inlet 73, part of the air flows in the air inlet channel 74 push the indication ball 31 upwards through the indication channel 72, and the rest of the air flows through the air inlet channel 74, passes through a quantitative cavity 83 according to a preset route, carries medicine powder in the quantitative cavity 83 and is discharged through the air outlet 75 connected with the suction nozzle 2.

The indicating cover plate 32 is made of transparent material, an opaque indicating mark 321 is arranged on the front surface of the indicating cover plate 32, and the position of the indicating mark 321 is the position of the upper section of the corresponding indicating channel 72 after the indicating cover plate 32 is installed. An indication display window 42 is provided on the front surface of the outer cover 4. When the entire device is not pressed, i.e., the cover 4 is in the original state, the indication display window 42 corresponds to the upper portion of the indication channel 72, and the indication ball 31 does not appear in the indication display window 42 due to gravity. After the patient performs the inhalation by using the device, the inhalation air flow pushes the indication ball 31 to move upwards, at this time, if the position of the indication ball 31 reaches or is higher than the position of the indication mark 321, the inhalation air flow at this time is up to the standard that can ensure the medication effect, and if the position of the indication ball 31 is lower than the position of the indication mark 321, the inhalation air flow needs to be increased in the subsequent continuous inhalation.

As shown in fig. 10-11, when the patient does not press the device housing 4, a dosing cavity 83 is located directly below the outlet of the cartridge 78, and the powder in the cartridge 78 will be dosed into the dosing cavity 83. When the patient presses the housing 4 once, the housing 4 drives the medicine dispenser 8 to rotate once, the quantitative cavity 83 with the medicine powder therein is rotated to the joint of the air inlet channel 74 and the air outlet 75, at this time, the patient brings the suction nozzle 2 into the oral cavity to perform the inhalation action, and the air flow carries the medicine powder in the quantitative cavity 83 through the air outlet channel 22, and finally enters the patient. At the same time, the next empty dosing pocket 83 rotates just below the outlet of the cartridge 78 to complete the next predetermined dose of powder to be used.

The suction nozzle 2 can enclose the main body 7, the airflow indicating assembly 3, the medicine dispenser 8 and the counting assembly 9, a counting window 21 is arranged on the plane of the suction nozzle 2 closest to the counting assembly 9, and numerals on part of the end surfaces of the high counting wheel 91 and the low counting wheel 92 can be seen through the counting window 21. The suction nozzle cover 1 is provided with the stop arm 11, when the suction nozzle cover 1 is completely buckled on the device, the stop arm 11 is contacted with the outer cover 4 to limit the downward movement of the outer cover 4, so that the device is ensured not to be touched and pressed by an external force in an unused state, and the actual inhalation administration is ensured to be used for each pressing movement of the outer cover 4.

In the description of the present utility model, it should be understood that the terms "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate orientations or positional relationships, merely to facilitate the simplified description of the present utility model, and do not indicate or imply that the devices or elements being referred to must have a particular orientation, be configured and operated in a particular orientation, and thus are not to be construed as limiting the present utility model. Furthermore, in the description of the present utility model, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.

The foregoing has shown and described the basic principles, principal features and advantages of the utility model. It will be understood by those skilled in the art that the present utility model is not limited to the embodiments described above, and that the above embodiments and descriptions are merely illustrative of the principles of the present utility model, and various changes and modifications may be made therein without departing from the spirit and scope of the utility model, which is defined by the appended claims. The scope of the utility model is defined by the appended claims and equivalents thereof.

Claims (10)

1. A reservoir type multi-dose dry powder inhaler comprising a mouthpiece cover, a mouthpiece, an airflow indicating assembly, an outer cover, a spring, a cartridge cover, a body, a dispenser, and a counting assembly, wherein:

The medicine bin is used for uniformly accommodating multiple doses of medicine powder, a non-closed cylindrical empty slot is connected below the medicine bin and used for accommodating the medicine distributor, and a channel matched with the suction nozzle is arranged on the non-closed cylindrical empty slot along the horizontal direction of the main body;

The medicine bin cover is connected with the medicine bin and is used for sealing the medicine powder stored in the medicine bin;

The two ends of the medicine distributor are provided with operation ratchet wheels, the outer cover is provided with a transmission arm, and the transmission arm is meshed with the operation ratchet wheels;

One end of the spring is connected with the medicine bin cover, and the other end of the spring is contacted with the inner part of the outer cover to give the outer cover resilience force opposite to the pressing direction;

The airflow indicating assembly comprises an indicating small ball and an indicating cover plate;

the counting assembly comprises a high-order counting wheel disc and a low-order counting wheel disc;

the suction nozzle can enclose the main body, the airflow indicating assembly, the medicine distributor and the counting assembly, a counting window is arranged on the plane of the suction nozzle closest to the counting assembly, and partial end surfaces of the high-position counting wheel disc and the low-position counting wheel disc can be seen through the counting window;

The medicine bin is characterized in that a predetermined air inlet air flow channel is arranged on the peripheral surface of the medicine bin, the air inlet air flow channel comprises a vertical indication channel, the indication channel can enable the indication small ball to move up and down freely along a straight line path, an indication display window is arranged on the outer cover, and the position change of the indication small ball can be observed through the indication display window.

2. The reservoir type multi-dose dry powder inhaler according to claim 1, wherein the indication display window corresponds to an upper section of the indication channel in a case where the integral dry powder inhaler is not pressed, i.e., the spring is not contracted by an external force.

3. The reservoir type multi-dose dry powder inhaler according to claim 1, wherein the indication cover plate is made of transparent material, and an opaque indication mark is arranged at a position corresponding to the upper section of the indication channel.

4. The reservoir type multi-dose dry powder inhaler as claimed in claim 1, wherein the main body portion is made of a transparent material.

5. A reservoir type multi-dose dry powder inhaler as claimed in claim 3, wherein the indicator ball is pushed by the flow of the inhalation air flow during use of the patient, the different positions of the indicator ball in the indicator pathway correspond to the intensity of the inhalation air flow, and when the indicator ball is pushed to the indicator or above the indicator position, the inhalation air flow reaches a preset standard, at which time the optimal effect of administration is ensured.

6. The reservoir type multi-dose dry powder inhaler according to claim 1, wherein a group of numbers 0 to 9 are sequentially arranged on the periphery of one end face of the low-level counting wheel disc, the center of the low-level counting wheel disc is a hollow hole, the hollow hole is polygonal, and a carry protrusion is arranged on the periphery of the other end of the low-level counting wheel disc.

7. The reservoir type multi-dose dry powder inhaler according to claim 6, wherein a set of numbers 0 to N, N being numbers greater than 1, are sequentially arranged on the circumference of one end face of the high-order counting wheel, the other end face of the high-order counting wheel is a gear structure which can be engaged with the carry protrusion on the low-order counting wheel, and a counting termination protrusion is arranged on the other end face of the high-order counting wheel.

8. The reservoir type multi-dose dry powder inhaler of claim 6, wherein the low count wheel is coaxially disposed with the dispenser.

9. The reservoir type multi-dose dry powder inhaler according to claim 8, wherein the drug dispenser is integrally formed in a cylindrical structure, a plurality of dosing holes are uniformly distributed on a curved surface of the drug dispenser, a single dosing hole can accommodate a single dose of powder, one end of the drug dispenser is of a closed structure and is provided with a polygonal protruding column, the protruding column can be matched with a central hollow hole of the low-position counting wheel disc, and the other end of the drug dispenser is provided with a sealing groove.

10. The reservoir type multi-dose dry powder inhaler according to claim 9, wherein a sealing bead is provided in the body at a position corresponding to the sealing groove in the body for accommodating the dispenser, and the sealing bead is tightly fitted to the sealing groove.