CN222523209U

CN222523209U - Sterile transfer bag and sterile transfer device comprising same

Info

Publication number: CN222523209U
Application number: CN202421426705.5U
Authority: CN
Inventors: 温韬; 孙奇威
Original assignee: Shanghai Basalmedia Technologies Co ltd
Current assignee: Shanghai Basalmedia Technologies Co ltd
Priority date: 2024-06-21
Filing date: 2024-06-21
Publication date: 2025-02-25
Anticipated expiration: 2034-06-21

Abstract

The present utility model relates to a sterile transfer bag and a sterile transfer device including the same. The sterile transfer bag is provided with a flexible storage space, the storage space is opened at a first end, the storage space is sealed and closed at a second end by adopting a passive valve cover, and the passive valve cover is provided with a fixing piece in sealing connection with the storage space and a sealing cover in detachable sealing connection with the fixing piece. The sterile transfer bag of the utility model can be used for fully sealing, sterilizing and rapidly transferring the preassembled plate.

Description

Sterile transfer bag and sterile transfer device comprising same

Technical Field

The utility model relates to the field of laboratory equipment, in particular to a sterile transfer bag and a sterile transfer device comprising the same.

Background

In the experimental, sampling or production process of life science products, sterile transportation and transfer are required in the whole process to ensure the quality of the life science products. The transfer is usually carried out by a prefilled plate of life science products, and at present, the prefilled plate is usually transferred by a sterile transfer chamber, placed in the transfer chamber, sterilized by Vaporized Hydrogen Peroxide (VHP) and then transferred.

However, such delivery means are small in number and long in time, and require sterilization during delivery, increasing the cost of delivery, and the disinfectant employed may contaminate the environment and even have an impact on the quality of the prefilled dishes.

Disclosure of utility model

In view of this, the present utility model provides a sterile transfer bag and sterile transfer device including the same that solves or at least alleviates one or more of the above-mentioned and other problems of the prior art.

In order to achieve the foregoing object, a first aspect of the present utility model provides a sterile transfer bag having a flexible storage space open at a first end and sealed closed at a second end with a passive valve cover having a securing member in sealing connection with the storage space and a flap in releasable sealing connection with the securing member.

In the sterile transfer bag, the fixing piece is provided with a connecting ring fixedly connected with the storage space and a clamping part connected with the connecting ring, wherein the inner periphery of the clamping part is provided with a first flange;

The outer periphery of the sealing cover is provided with a first groove, the first groove is suitable for being clamped with the first flange, a notch corresponding to the first flange is further formed in the first groove, and the first flange can move in or out of the notch, so that the sealing cover is sealed to be closed or separated from the fixing piece.

In the aseptic transfer bag as described above, optionally, the first end of the storage space is heat-sealed or adhesively attached to the attachment ring of the fastener.

In the sterile transfer bag as described above, optionally, the fixing member is connected with a handle having a holding portion and a connecting portion, one end of the connecting portion is connected to the connecting ring, and the holding portion is connected to the other end of the connecting portion.

In the aseptic transfer bag as described above, optionally, the connecting portion is an L-shaped rod, one end of the L-shaped rod is fixedly connected to a connection portion between the connecting ring and the clamping portion, the other end of the L-shaped rod is connected to the holding portion, and the end of the holding portion extends away from the storage space.

In the aseptic transfer bag as described above, optionally, the outer periphery of the engaging portion is provided with a second groove, the flap has a central groove, and the inner periphery of the central groove is provided with a second flange.

In the aseptic transfer bag as described above, optionally, the inner periphery of the fixing member is a bevel cut, and the outer periphery of the sealing cover is provided with a bevel cut corresponding to the bevel cut and adapted to be closed and covered with the fixing member.

In order to achieve the foregoing object, a second aspect of the present utility model provides a sterile transfer device comprising a sterile transfer bag as described in the first aspect, and a drive valve cap for mounting to a bulkhead of a sterile isolation compartment, the drive valve cap being capable of coupling with the passive valve cap and opening the closure cap of the passive valve cap out of the fixture.

In the aseptic transfer apparatus as described above, optionally, the active valve cover includes a mount secured to the bulkhead of the aseptic isolation compartment and a coupling cover detachably connected to the mount;

The outer periphery of the mounting piece is provided with a third groove which is used for being clamped with the bulkhead of the isolation cabin, the inner periphery of the mounting piece is provided with a fourth flange which is used for being clamped with a fixing piece of the passive valve cover of the sterile transfer bag;

The coupling cover is provided with a middle boss, and the periphery of the middle boss is provided with a third flange, and the third flange is used for being coupled with the sealing cover of the passive valve cover.

In the aseptic transfer device as described above, optionally, the active valve cover further comprises a hinge mechanism for hinge-connecting the coupling cover with the mount, and a locking mechanism comprising a press-fit portion at a periphery of the coupling cover and a resilient handle for press-fitting or unlocking the press-fit portion.

The utility model provides a sterile transfer bag, which is provided with a flexible storage space, wherein the second end of the flexible storage space is sealed and closed by a passive valve cover, the first end of the flexible storage space is opened for placing materials to be transferred aseptically, such as preassembled plates and the like, and then the first end is sealed and closed, so that the storage space is sealed and closed, and an aseptic storage space is formed through irradiation sterilization, and the materials in the storage space can be transferred aseptically through the sterile transfer bag.

The utility model also provides a sterile transfer device, which comprises the sterile transfer bag and the active valve cover arranged in the sterile transfer cabin, wherein the active valve cover can be coupled with the passive valve cover of the sterile transfer bag and can be sealed and opened, so that the storage space of the sterile transfer bag is communicated with the sterile transfer cabin, and materials can be transferred from the sterile transfer bag into the sterile transfer cabin at one time, thereby shortening the transfer time, saving the transfer cost, sealing the whole transfer process and preventing external pollution.

Drawings

The present disclosure will become more apparent with reference to the accompanying drawings. It is to be understood that these drawings are solely for purposes of illustration and are not intended as a definition of the limits of the utility model. In the figure:

FIG. 1 is a schematic view of one embodiment of a sterile transfer bag of the present utility model;

FIG. 2 is a schematic view of an active valve cap of one embodiment of the sterile transfer device of the present utility model (the sterile isolation pod is shown);

FIG. 3 is a schematic illustration of the coupling of an active valve cover to a passive valve cover of one embodiment of the sterile transfer device of the present utility model;

fig. 4 is a schematic view of an embodiment of the aseptic transfer device of the present utility model, with the active valve cover coupled to the passive valve cover and then opened.

The reference numerals 1-storage space, 10-sterile transfer bag, 11-first end, 12-second end, 2-passive valve cap, 3-fastener, 31-connecting ring, 32-snap-in portion, 33-second groove, 34-first flange, 35-first groove, 36-miter cut, 4-flap, 41-center groove, 42-second flange, 43-miter cut, 5-handle, 51-handhold portion, 52-connecting portion, 6-active valve cap, 61-mount, 62-coupling cap, 63-third groove, 64-third flange, 65-intermediate boss, 66-handle, 67-hinge mechanism, 68-locking mechanism, 69-fourth flange, 7-sterile isolation compartment, 71-bulkhead, 8-press-in portion, 9-resilient handle.

Detailed Description

The structure, composition, features, advantages, etc. of the sterile transfer bag of the present utility model and the sterile transfer device including the same will be described below by way of example with reference to the accompanying drawings and specific embodiments, however, all descriptions should not be construed as limiting the present utility model in any way.

Furthermore, to the extent that any individual feature described or implied in the embodiments set forth herein, or any individual feature shown or implied in the figures, the utility model still allows any combination or deletion of such features (or equivalents thereof) without any technical hurdle, and further embodiments according to the utility model are considered to be within the scope of the disclosure herein.

It should also be noted that the terms "inner", "outer", and the like indicate an orientation or positional relationship based on the orientation or positional relationship of the sterile transfer bag as shown in the drawings, and are merely for convenience in describing the present disclosure and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present disclosure.

In the description of the present disclosure, the meaning of "a plurality" is at least two, such as two, three or more, etc., unless explicitly defined otherwise.

Furthermore, the terms "first," "second," "third," "fourth" and the like are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "first", "second", "third", and "fourth" may explicitly or implicitly include at least one such feature.

FIG. 1 is a schematic view of one embodiment of a sterile transfer bag of the present utility model.

As can be seen in fig. 1, the sterile transfer bag 10 of the present utility model comprises a storage space 1 and a passive valve cover 2, said storage space 1 having a first end 11 and a second end 12. When the passive valve cover 2 is opened, it is coupled with the active valve cover 6 and is actively guided to be opened by the active valve cover 6 (as shown in fig. 2) so that the storage space 1 thereof is opened to the outside, for example, the aseptic isolation compartment 7 or the like.

The first end 11 of the storage space 1 is opened, and the opened first end 11 is sealed and closed after placing the material to be aseptically transferred, so as to facilitate sterilization and disinfection of the aseptic transfer bag 10 and aseptic transfer, and the sterilization mode adopts radiation sterilization, so as to avoid pollution of the aseptic transfer bag 10 and the material therein by the disinfectant. The sealing closure of the first end 1 may be a heat seal and the material may be a pre-filled plate or the like.

The storage space 1 is made of flexible materials, and can be set into storage spaces 1 with different capacities and sizes according to the quantity, the shape and the size of placed materials when in use, so that materials are saved, and the materials are conveniently taken and transferred.

The second end 12 of the storage space 1 is sealed and closed by a passive valve cover 2, and the passive valve cover 2 is provided with a fixing piece 3 fixedly and hermetically connected with the storage space 1 and a sealing cover 4 detachably and hermetically connected with the fixing piece 3. Optionally, the passive valve cover 2 may further be provided with a handle 5 connected to the fixing member 3, as can be seen from the embodiment of fig. 1, the handle 5 extends to the outside of the storage space 1, so as to facilitate grasping by a user and performing operations such as clamping and transferring the sterile transfer bag 10, thereby accelerating the transferring process.

The fixing member 3 has an integrally formed connecting ring 31 and a clamping portion 32, and the fixing member 3 may be in a circular ring shape or a square shape to open a port at the first end 11 of the storage space 1, so that a material placed in the storage space 1 may be placed in or taken out from the open position of the fixing member 3. As shown in the drawing, the connection ring 31 is hermetically connected to the storage space 1, and the sealing connection method is not limited to a connection method such as heat sealing, adhesion, and the like. The sealing of the fixing piece 3 can ensure that the materials in the storage space 1 are not polluted, and the sterile state is kept, so that the quality of the materials is ensured.

The connecting ring 31 can be in sealing connection with the outer wall of the port of the first end 11 of the storage space 1, so that the first end 11 of the storage space 1 can be reinforced, the external contact to the port of the first end 11 is reduced, and the port is prevented from being damaged. In an alternative embodiment, the connecting ring 31 may be disposed against the inner wall of the port of the first end 11, so long as it can be sealingly connected to the storage space 1.

The outer periphery of the clamping portion 32 is provided with a second groove 33, and the second groove 33 is used for clamping the active valve cover 6 (as shown in fig. 2). The inner periphery of the clamping part 32 is provided with a first flange 34, a corresponding first groove 35 is arranged at the outer periphery of the sealing cover 4, the first groove 35 is suitable for clamping the first flange 34, a notch (not shown in the figure) corresponding to the first flange 34 is arranged at the first groove 35, the first flange 34 can be moved into and embedded into the first groove 35 from the notch by rotating the sterile transmission bag 10 so as to enable the sealing cover 4 to be sealed and closed with the fixing piece 3, and the first flange 34 can be moved out of the first groove 35 by rotating the sterile transmission bag 10 so as to enable the sealing cover 4 to be separated from the fixing piece 3.

The handle 5 has a holding portion 51 and a connecting portion 52, and the holding portion 51 and the connecting portion 52 may be integrally formed or may be fixedly connected to each other. One end of the connecting portion 52 is connected to the connecting ring 31 of the fixing member 3, and the hand-held portion 51 is connected to the other end of the connecting portion 52 and extends outwardly away from the storage space 1.

As shown in the figure, the connecting portion 5 is an L-shaped rod, one end of the L-shaped rod is fixedly connected to the connecting portion between the connecting ring 31 and the clamping portion 32, and the L-shaped rod extends to the outside of the storage space 1 and the bending region thereof bends towards the storage space 1, so that the hand-holding portion 51 is located at the outside of the storage space 1, and the end of the hand-holding portion 51 is far away from the storage space 1, thereby leaving a space for a user to grasp.

The number of the handpieces 51 is not limited to two as in the embodiment shown in the drawings, but may be plural, so that the handpieces can be easily grasped by a user from various angles to facilitate the operations of taking, rotating, etc. the sterile transfer bag 10.

According to the embodiment shown in the drawings, the sealing cap 4 has a central groove 41, and the inner periphery of the central groove 41 is provided with a second flange 42, and the second flange 42 is used for being clamped to the driving valve cap 6 (as shown in fig. 2). The second flange 42 may be snapped into engagement with the third flange 64 of the active valve cap 6 (as shown in fig. 3), the second flange 42 may be notched (not shown), and the third flange 64 may be moved into snap-fit engagement with the central recess 41 or the third flange 64 may be moved out of the central recess 41 by rotating the sterile transfer bag 10.

It should be noted that, the notch of the second flange 42 is staggered from the notch of the first groove 35, that is, when the third flange 64 of the active valve cover 6 is clamped and embedded into the central groove 41 of the sealing cover 4 of the passive valve cover 2, the first flange 34 of the passive valve cover 2 can be removed from the notch corresponding to the first groove 35, so that the active valve cover 6 can link to open the sealing cover 4 to complete the aseptic transfer of the material in the storage space 1.

In the embodiment shown in the figures, optionally, the inner periphery of the fixing member 3 is provided with a bevel 36, and the outer periphery of the sealing cover 4 is provided with a bevel 43 corresponding to the bevel 36, and the bevel 36 cooperates with the bevel 43 to facilitate the sealing closing or separating of the sealing cover 4 from the fixing member 3.

Fig. 2 is a schematic view of an active valve cap (shown in a sterile isolation pod) of one embodiment of the sterile transfer device of the present utility model.

As can be seen from the figure, the active valve cap 6 is mounted to the bulkhead 71 of the aseptic isolation compartment 7, the active valve cap 6 opening into the interior of the aseptic isolation compartment 7. The active valve cover 6 has a mounting member 61 and a coupling cover 62, and the active valve cover 6 is fixed to the bulkhead 71 by the mounting member 61.

Specifically, as shown, the outer periphery of the mounting member 61 is provided with a third recess 63, and the bulkhead 71 can be snap-fitted into the third recess 63, thereby securing the active valve cover 6 to the bulkhead 71 of the aseptic isolation compartment 7.

The inner periphery of the mounting member 61 is provided with a fourth flange 69, which fourth flange 69 is adapted to be snapped onto the fixture 3 (shown in fig. 3) of the passive valve cap 2 of the sterile transfer bag 10. As can be seen from the figure, the fourth flange 69 is an inclined plane, and the inclined plane can facilitate the connection of the clamping portion 32 of the passive valve cover 2, so that the fourth flange 69 is clamped and fixed to the clamping portion 32 (as shown in fig. 3) and is not easy to fall off.

As can also be seen from the figure, the coupling cap 62 is provided with a central boss 65 at the end remote from the aseptic isolation compartment 7, which central boss 65 is intended to be snap-fitted with the closure cap 4 of the passive valve cap 2. Specifically, the peripheral edge of the intermediate boss 65 is provided with a third flange 64, which third flange 64 is adapted to be coupled to the flap 4 of the passive valve cover 2 (as shown in fig. 3). In an alternative embodiment, the other end of the coupling cover 62 is provided with a handle 66, and the handle 66 may facilitate the opening or closing of the active valve cover 6 by a user.

According to the embodiment shown in the drawings, the active valve cover 6 optionally further comprises a hinge mechanism 67 and a locking mechanism 68, wherein two ends of the hinge mechanism 67 are respectively connected to the coupling cover 62 and the mounting member 61, and when the active valve cover 6 is opened, the active valve cover 6 can be rotated to be opened around the hinge point of the connecting mechanism 67 and the mounting member 61, and when a product is placed or taken out, the active valve cover 6 can be hung at the hinge point of the mounting member 61 to prevent the active valve cover 6 from being lost and polluted.

As can be seen from the embodiment shown in the figures, the locking mechanism 68 comprises a press-fit portion 8 located at the periphery of the coupling cover 62 and a resilient handle 9, wherein the resilient handle 9 can be pressed against and locked to the press-fit portion 8, and the resilient handle 9 is moved to unlock the press-fit portion 8 when the driving valve cover 6 is closed and opened by pressing and sealing the edge of the coupling cover 62.

Fig. 3 is a schematic view of the coupling of an active valve cover and a passive valve cover of one embodiment of the sterile transfer device of the present utility model.

As is clear from the figure, the passive valve cap 2 of the sterile transfer bag 10 is coupled with the active valve cap 6. Specifically, the coupling cover 62 of the active valve cover 6 is coupled with the sealing cover 4 of the passive valve cover 2, and the mounting member 61 of the active valve cover 6 is coupled with the clamping portion 32 of the passive valve cover 2. Specifically, as shown in the figure, the third flange 64 of the coupling cover 62 and the second flange 42 of the sealing cover 4 are clamped with each other, the fourth flange 69 of the mounting member 61 is clamped with the second groove 33 of the clamping portion 32, and thus the storage space 1 of the passive valve cover 2 is fixedly connected to the bulkhead 71 of the aseptic isolation compartment 7 through the clamping of the clamping portion 32 and the mounting member 61.

By rotating the aseptic transfer bag 10, the sealing cover 4 of the passive valve cover 2 is separated from the clamping part 32, the clamping part 32 of the passive valve cover 2 is clamped and fixed with the mounting piece 61 of the active valve cover 6, and meanwhile, the sealing cover 4 of the passive valve cover 2 is clamped and fixed with the coupling cover 62 of the active valve cover 6. The coupling cap 62 can thus be opened together with the cap closure 4 into the aseptic transfer compartment 7, so that the material to be transferred aseptically can be removed from the aseptic transfer bag 10 and transferred to the aseptic transfer compartment 7, or the material can be transferred from the aseptic transfer compartment 7 into the aseptic transfer bag 10.

As is clear from the figure, the storage space 1 of the passive valve cover 2 is fixedly connected to the bulkhead 71 of the aseptic isolation compartment 7 by the clamping connection of the clamping connection part 32 and the mounting piece 61 of the active valve cover 6, and the coupling cover 62 of the active valve cover 6 is coupled with the passive valve cover 2 and is opened around the hinge mechanism 67 at the hinge point of the mounting piece 61, so that materials to be transferred aseptically can be put in or taken out between the aseptic isolation compartment 7 and the aseptic isolation bag 1.

The technical scope of the present utility model is not limited to the above description, and those skilled in the art may make various changes and modifications to the above-described embodiments without departing from the technical spirit of the present utility model, and these changes and modifications should be included in the scope of the present utility model.

Claims

1. The sterile transfer bag is characterized in that the sterile transfer bag (10) is provided with a flexible storage space (1), the storage space is opened at a first end (11), the storage space is sealed and closed by a passive valve cover (2) at a second end (12), and the passive valve cover (2) is provided with a fixing piece (3) in sealing connection with the storage space and a sealing cover (4) in detachable sealing connection with the fixing piece (3).

2. The sterile transfer bag according to claim 1, characterized in that the securing element (3) has a connecting ring (31) fixedly connected to the storage space (1) and a clamping part (32) connected to the connecting ring (31), the inner periphery of the clamping part (32) being provided with a first flange (34);

The outer periphery of the sealing cover (4) is provided with a first groove (35), the first groove (35) is suitable for being clamped with the first flange (34), a notch corresponding to the first flange (34) is further formed in the first groove (35), and the first flange (34) can move in or out of the notch, so that the sealing cover (4) is sealed to be closed or separated from the fixing piece (3).

3. Sterile transfer bag according to claim 2, characterized in that the first end (11) of the storage space (1) is heat-sealed or adhesively connected to the connecting ring (31) of the securing element (3).

4. The sterile transfer bag according to claim 2, wherein the holder (3) is connected with a handle (5), the handle (5) having a hand-held portion (51) and a connecting portion (52), one end of the connecting portion (52) being connected to the connection ring (31), the hand-held portion (51) being connected to the other end of the connecting portion (52).

5. The sterile transfer bag of claim 4, wherein the connecting portion (52) is an L-shaped rod, one end of the L-shaped rod is fixedly connected to a connection between the connecting ring (31) and the clamping portion (32), the other end of the L-shaped rod is connected to the hand-held portion (51), and a distal end of the hand-held portion (51) extends away from the storage space (1).

6. The sterile transfer bag according to claim 2, wherein the outer periphery of the snap-in portion (32) is provided with a second groove (33), the flap (4) has a central groove (41), and the inner periphery of the central groove (41) is provided with a second flange (42).

7. Sterile transfer bag according to claim 1, characterized in that the inner periphery of the holder (3) is provided with a chamfer (36), and the outer periphery of the flap (4) is provided with a chamfer (43) corresponding to the chamfer (36) adapted to be closed with the holder (3).

8. A sterile transfer device, characterized in that it comprises a sterile transfer bag (10) according to any one of claims 1-7, and an active valve cap (6), the first end (11) of the sterile transfer bag (10) being sealed closed, the active valve cap (6) being intended to be mounted to a bulkhead (71) of a sterile compartment (7), the active valve cap (6) being able to couple with the passive valve cap (2) and to open the closure cap (4) of the passive valve cap (2) apart from the fixing (3).

9. The sterile transfer device according to claim 8, wherein the active valve cover (6) comprises a mounting (61) fixed to the bulkhead (71) of the sterile isolation compartment (7) and a coupling cover (62) disconnectable from the mounting (61);

The outer periphery of the mounting piece (61) is provided with a third groove (63), the third groove (63) is used for being clamped with the bulkhead (71) of the isolation cabin, the inner periphery of the mounting piece (61) is provided with a fourth flange (69), and the fourth flange (69) is used for being clamped with a fixing piece (3) of the passive valve cover (2) of the sterile transfer bag;

The coupling cover (62) is provided with a middle boss (65), and the periphery of the middle boss (65) is provided with a third flange (64), and the third flange (64) is used for being coupled with the sealing cover (4) of the passive valve cover (2).

10. The sterile transfer device according to claim 9, wherein the active valve cap (6) further comprises a hinge mechanism (67) and a locking mechanism (68), the hinge mechanism (67) being for hinging the coupling cap (62) with the mounting (61), the locking mechanism (68) comprising a press-fit portion (8) at the periphery of the coupling cap (62) and a resilient handle (9), the resilient handle (9) being for pressing or releasing the press-fit portion (8).