CN222379713U - Optical path module and biochemical analyzer - Google Patents
Optical path module and biochemical analyzer Download PDFInfo
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- CN222379713U CN222379713U CN202420621977.4U CN202420621977U CN222379713U CN 222379713 U CN222379713 U CN 222379713U CN 202420621977 U CN202420621977 U CN 202420621977U CN 222379713 U CN222379713 U CN 222379713U
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- 230000003287 optical effect Effects 0.000 title claims abstract description 142
- 238000001514 detection method Methods 0.000 claims abstract description 76
- 239000003153 chemical reaction reagent Substances 0.000 claims description 24
- 230000004308 accommodation Effects 0.000 claims description 3
- 238000012742 biochemical analysis Methods 0.000 claims 2
- 238000011534 incubation Methods 0.000 abstract description 7
- 239000000523 sample Substances 0.000 description 23
- 230000000694 effects Effects 0.000 description 3
- 239000011259 mixed solution Substances 0.000 description 3
- 230000002829 reductive effect Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 230000002411 adverse Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000013307 optical fiber Substances 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
The utility model is suitable for the technical field of medical instruments, and particularly relates to an optical path module and a biochemical analyzer, wherein the optical path module comprises a first light guide piece, a second light guide piece, a third light guide piece and a fourth light guide piece, the first end of the third light guide piece corresponds to a first detection piece, the first end of the fourth light guide piece corresponds to a second detection piece, the second end of the third light guide piece and the second end of the fourth light guide piece are both arranged in a containing space, light of a first light source is guided to the first detection piece by the third light guide piece after forming scattered light through a reaction unit of a first annular groove, and light of a second light source is guided to the second detection piece by the fourth light guide piece after forming scattered light through a reaction unit of a second annular groove, so that the influence of incubation temperature of a carrier on the first detection piece and the second detection piece is avoided.
Description
Technical Field
The utility model belongs to the technical field of medical instruments, and particularly relates to an optical path module and a biochemical analyzer.
Background
The biochemical analyzer has the advantages of high measurement speed, high accuracy and small consumption of reagents, and is widely used in the medical field (such as hospitals at all levels, epidemic prevention stations and family planning service stations).
The existing biochemical analyzer is generally provided with a carrying disc, a plurality of reaction containers can be arranged on the circumference of the carrying disc, samples and reagents can be added into the reaction containers to enable the samples and the reagents to react to form mixed liquid, when the carrying disc is rotated, the mixed liquid in the reaction containers is irradiated by a light source, and transmitted light or scattered light of the reaction containers is detected by a photometer. Existing biochemical analyzers typically place the test element near the reaction vessel on the carrier plate, which can have adverse effects on the test element due to the fact that the incubation temperature of the sample on the carrier plate is generally higher than the desired operating temperature of the test element.
Disclosure of utility model
The utility model provides an optical path module and a biochemical analyzer, and aims to solve the problem that the incubation temperature of a carrier disc of the existing biochemical analyzer has adverse effects on a detection element.
The utility model is realized in such a way that the optical path module is applied to a biochemical analyzer, the biochemical analyzer is provided with a rotatable carrying disc, and the optical path module comprises a first light guide piece, a second light guide piece, a third light guide piece and a fourth light guide piece:
The carrier disc is provided with a first annular groove and a second annular groove which are concentric, the first annular groove is arranged at the periphery of the second annular groove, the first annular groove and the second annular groove are used for bearing a reaction unit, the reaction unit is used for mixing a sample with a reagent to react, and an accommodating space is arranged between the reaction unit on the first annular groove and the reaction unit on the second annular groove;
The first end of the third light guide piece corresponds to the first detection piece, the first end of the fourth light guide piece corresponds to the second detection piece, the second end of the third light guide piece and the second end of the fourth light guide piece are both arranged in the accommodating space, and the first end of the third light guide piece and the first end of the fourth light guide piece are arranged far away from the accommodating space;
The first light guide piece comprises a first light path channel which is arranged at the periphery of the first annular groove and corresponds to the second end of the third light guide piece, the first light path channel is connected with the first light source and is used for guiding light which is injected into the first light path channel by the first light source to the reaction unit of the first annular groove to form scattered light, so that the scattered light is guided to the first detection piece by the third light guide piece;
the second light guide piece comprises a second light path channel which is arranged on the inner periphery of the second annular groove and corresponds to the second end of the fourth light guide piece, the second light path channel is connected with a second light source and is used for guiding light which is injected into the second light path channel by the second light source to the reaction unit of the second annular groove to form scattered light, and the scattered light is guided to the second detection piece by the fourth light guide piece.
Further, the light path module further comprises a fifth light guide member and a sixth light guide member;
the fifth light guide piece and the sixth light guide piece are arranged in the accommodating space;
The fifth light guide piece is provided with a third light path channel corresponding to the first light path channel, the third light path channel is connected with the second end of the third light guide piece, and a preset angle included angle is formed between the third light path channel and the optical axis of the emergent light of the first light path channel;
The sixth light guide piece is provided with a fourth light path channel corresponding to the second light path channel, the fourth light path channel is connected with the second end of the fourth light guide piece, and a preset angle included angle is formed between the fourth light path channel and the optical axis of the emergent light of the second light path channel.
Further, the third optical path is gradually upwardly offset from an end close to the first optical path toward an end far from the first optical path, and the fourth optical path is gradually upwardly offset from an end close to the second optical path toward an end far from the second optical path.
Further, the preset included angle includes 10 degrees to 30 degrees.
Further, the fifth light guide member is provided with a first reference light path channel corresponding to the first light path channel, and the sixth light guide member is provided with a second reference light path channel corresponding to the second light path channel;
The first reference light path channel is connected with a first reference detection piece;
the second reference light path channel is connected with a second reference detection piece.
Further, the first reference light path channel comprises a first section channel, a second section channel and a first reflecting piece, and the second reference light path channel comprises a third section channel, a fourth section channel and a second reflecting piece;
The first section channel is connected with the first reference detection piece through the second section channel:
The third section channel is connected with the second reference detection piece through the fourth section channel:
The first reflecting piece is arranged between the first section channel and the second section channel and is used for reflecting light entering the first section channel to the second section channel and then emitting the light to the first reference detecting piece;
The second reflecting piece is arranged between the third section channel and the fourth section channel and is used for reflecting the light entering the third section channel to the fourth section channel and then emitting the light to the second reference detecting piece.
Further, the diameter of the first light path channel gradually becomes smaller from one end close to the first light source to one end far away from the first light source, and the diameter of the second light path channel gradually becomes smaller from one end close to the second light source to one end far away from the second light source.
Further, at least one first diaphragm is arranged in the first light path channel, and at least one second diaphragm is arranged in the second light path channel.
Further, a first mounting groove and a second mounting groove are formed in the third light path channel, the first mounting groove is used for mounting the first detection piece, and the third mounting groove is used for mounting the first condensing lens;
A third mounting groove and a fourth mounting groove are arranged in the fourth light path channel, the third mounting groove is used for mounting the second detection piece, and the fourth mounting groove is used for mounting the second condensing lens.
In a second aspect, the present application also provides a biochemical analyzer comprising:
The carrier disc is provided with a first annular groove and a second annular groove which are concentrically arranged, the first annular groove is arranged at the periphery of the second annular groove, the first annular groove and the second annular groove are used for bearing a reaction unit, the reaction unit is used for mixing a sample with a reagent to react, and an accommodating space is arranged between the reaction unit on the first annular groove and the reaction unit on the second annular groove;
A detection assembly including a first detection member and a second detection member, and
Such as the optical path module described above.
The optical path module has the advantages that the optical path module is applied to a biochemical analyzer, the optical path module comprises a first optical guide piece, a second optical guide piece, a third optical guide piece and a fourth optical guide piece, a carrying disc of the analyzer is provided with a first annular groove and a second annular groove which are concentric, the first annular groove is arranged on the periphery of the second annular groove, the first annular groove and the second annular groove are used for carrying a reaction unit, the reaction unit is used for mixing a sample and a reagent to react, an accommodating space is formed between the reaction unit on the first annular groove and the reaction unit on the second annular groove, the first end of the third optical guide piece corresponds to the first detection piece, the first end of the fourth optical guide piece corresponds to the second detection piece, the second end of the third optical guide piece and the second end of the fourth optical guide piece are both arranged in the accommodating space, the first end of the third optical guide piece and the first end of the fourth optical guide piece are far away from the accommodating space, the first optical guide piece comprises a first optical path channel which is arranged on the periphery of the first annular groove and corresponds to the second end of the third optical guide piece, the first optical path channel which is used for carrying the reaction unit, the first optical path channel which is used for enabling the sample to react with the reagent, the reaction unit is arranged between the reaction unit and the reaction unit on the first annular groove and the first optical channel and the second optical channel which is used for enabling the first optical channel to be connected to the first optical channel and the second optical channel to be used for realizing the reaction unit. Because the first end of third light guide corresponds with first detection spare, and the first end of fourth light guide corresponds with the second detection spare, and the second end of third light guide and the second end of fourth light guide all set up in accommodation space, and accommodation space sets up is kept away from to the first end of third light guide and the first end of fourth light guide, has consequently avoided the incubation temperature of carrying the dish to the influence of first detection spare and second detection spare.
Drawings
FIG. 1 is a schematic top view of a three-dimensional structure of an embodiment of a biochemical analyzer according to the present application;
FIG. 2 is a schematic top view of one embodiment of a biochemical analyzer according to the present application;
FIG. 3 is a schematic bottom view of one embodiment of a biochemical analyzer according to the present application;
FIG. 4 is a schematic side view of one embodiment of a biochemical analyzer according to the present application;
FIG. 5 is a schematic view of a cross-sectional partial structure taken along line A-A in FIG. 4;
FIG. 6 is a schematic diagram of an embodiment of an optical path module according to the present application;
FIG. 7 is a schematic side view of one embodiment of an optical path module provided by the present application;
FIG. 8 is a schematic cross-sectional view taken along line C-C of FIG. 7;
fig. 9 is a schematic cross-sectional view taken along line B-B in fig. 7.
The disc comprises a disc surface 100, a fixed disc, 110, a disc plane 120, an outer disc annular surface 130, a disc inner annular surface 200, a carrier disc 210, a first annular groove 220, a second annular groove 311, a first light source 312, a second light source 321, a first detection piece 322, a second detection piece 331, a first reference detection piece 332, a second reference detection piece 341, a first diaphragm 342, a second diaphragm 410, a first light guide piece 411, a first light path channel 420, a second light guide piece 421, a second light path channel 430, a third light guide piece 440, a fourth light guide piece 450, a fifth light guide piece 451, a third light path channel 452, a first reference light path channel 453, a first section channel 454, a second section channel 455, a first reflection piece 456, a first mounting groove, a second mounting groove 457, a 460, a sixth light guide piece 461, a fourth light path channel 462, a second reference light path channel 463, a third section channel 466, a fourth section channel 465, a fourth section channel 457, a fourth section channel 467, a fourth section channel.
Detailed Description
The present utility model will be described in further detail with reference to the drawings and examples, in order to make the objects, technical solutions and advantages of the present utility model more apparent. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the utility model.
According to the application, the first end of the third light guide piece corresponds to the first detection piece, the first end of the fourth light guide piece corresponds to the second detection piece, the second end of the third light guide piece and the second end of the fourth light guide piece are both arranged in the accommodating space, and the first end of the third light guide piece and the first end of the fourth light guide piece are arranged far away from the accommodating space, so that the influence of incubation temperature of the carrier plate on the first detection piece and the second detection piece is avoided, and the detection accuracy is ensured.
Example 1
As shown in fig. 1 to 9, the present embodiment provides an optical path module, which is applied to a biochemical analyzer, wherein the biochemical analyzer is provided with a rotatable carrier disc 200, and the optical path module includes a first light guide 410, a second light guide 420, a third light guide 430 and a fourth light guide 440:
The carrier 200 is provided with a first ring groove 210 and a second ring groove 220 which are concentric, the first ring groove 210 is arranged at the periphery of the second ring groove 220, the first ring groove 210 and the second ring groove 220 are used for carrying a reaction unit, the reaction unit is used for mixing a sample with a reagent to react, and an accommodating space is formed between the reaction unit on the first ring groove 210 and the reaction unit on the second ring groove 220;
The first end of the third light guide 430 corresponds to the first detecting member 321, the first end of the fourth light guide 440 corresponds to the second detecting member 322, and the second end of the third light guide 430 and the second end of the fourth light guide 440 are both disposed in the receiving space;
The first light guide 410 includes a first light path 411 disposed at the periphery of the first ring groove 210 and corresponding to the second end of the third light guide 430, the first light path 411 being connected to the first light source 311, for guiding the light injected into the first light source 311 into the first light path 411 to the reaction unit of the first ring groove 210 to form scattered light, so as to be guided to the first detection member 321 by the third light guide 430;
The second light guide member 420 includes a second light path 421 disposed at an inner periphery of the second ring groove 220 and corresponding to the second end of the fourth light guide member 440, and the second light path 421 is connected to the second light source 312, so that the light guided by the second light source 312 into the second light path 421 is guided to the reaction unit of the second ring groove 220 to form scattered light, so as to be guided to the second detection member 322 by the fourth light guide member 440.
In implementation, the optical path module provided by the application is applied to a biochemical analyzer, the biochemical analyzer is used for measuring chemical components in body fluid, and the body fluid comprises, but is not limited to, blood tissue fluid and the like.
In some embodiments, the biochemical analyzer has a stage (not shown), a fixed disk 100 mounted on the stage, and a driving motor (not shown) mounted on the stage, which is connected to the stage 200 for driving the stage 200 to rotate.
The carrier plate 200 has a first ring groove 210 and a second ring groove 220, the first ring groove 210 and the second ring groove 220 are concentrically arranged, and the first ring groove 210 is arranged at the periphery of the second ring groove 220, and the first ring groove 210 and the second ring groove 220 are annular and are used for carrying a plurality of reaction units which are circumferentially arranged.
In some embodiments, the reaction unit may be a vessel that can be detachably combined with the carrier plate 200, for example, the reaction unit may be a reaction cup, the carrier plate 200 is provided with a slot, the reaction cup may be inserted into the slot, and then a sample and a reagent are added into the reaction cup, so that the sample and the reagent are mixed to react.
The first light guide 410 is located at the periphery of the first ring groove 210, the second light guide 420 is located at the inner periphery of the second ring groove 220, and in operation, as shown in fig. 1, the fixed disk 100 is surrounded by the disk plane 110, the disk outer ring surface 120 and the disk inner ring surface 130 to form an annular inner space, and the first ring groove 210 and the second ring groove 220 can be accommodated in the inner space and rotate along the annular inner space. The first light guide 410 is mounted on the outer disk surface 120, i.e., the first light guide 410 is located at the outer periphery of the first ring groove 210, and the second light guide 420 is mounted on the inner disk surface 130, i.e., the second light guide 420 is located at the inner periphery of the second ring groove 220.
In some embodiments, the first light source 311 and the second light source 312 refer to devices or components capable of emitting light, such as, without limitation, laser emitters.
In some embodiments, the third light guide 430 and the fourth light guide 440 may use optical fibers or other components with light guiding functions, without limitation.
The first light guide 410 is provided with a first light path 411 therein, the first light path 411 is connected with the first light source 311, so that the light emitted from the first light source 311 passes through the first light path 411 and then is emitted to the reaction unit of the first ring groove 210 to form scattered light, in other words, the light emitted from the first light path 411 is emitted from the outside of the first ring groove 210 to the inside direction of the first ring groove 210, and thus can be guided to the first detection member 321 by the third light guide 430, thereby realizing the light detection function of the reaction unit on the first ring groove 210.
Similarly, a second light path channel 421 is disposed in the second light guide member 420, and the second light path channel 421 is connected to the second light source 312, so that the light emitted from the second light source 312 passes through the second light path channel 421 and then is emitted to the reaction unit of the second ring groove 220 to form scattered light, in other words, the light emitted from the second light path channel 421 is emitted from the second ring groove 220 to the outside of the second ring groove 220, so that the light can be guided to the second detection member 322 by the fourth light guide member 440, and the light detection function of the reaction unit on the second ring groove 220 is realized.
The optical path module of the present application is applied to a biochemical analyzer, the optical path module comprises a first optical guide 410, a second optical guide 420, a third optical guide 430 and a fourth optical guide 440, the carrier 200 of the analyzer is provided with a first annular groove 210 and a second annular groove 220 which are concentric, the first annular groove 210 is arranged at the periphery of the second annular groove 220, the first annular groove 210 and the second annular groove 220 are used for carrying a reaction unit for mixing a sample and a reagent to react, an accommodating space is arranged between the reaction unit on the first annular groove 210 and the reaction unit on the second annular groove 220, a first end of the third optical guide 430 corresponds to the first detection element 321, a first end of the fourth optical guide 440 corresponds to the second detection element 322, a second end of the third optical guide 430 and a second end of the fourth optical guide 440 are both arranged in the accommodating space, the first end of the third optical guide 430 and the first end of the fourth optical guide 440 are far away from the accommodating space, the first optical guide 410 comprises a first channel 411 arranged at the periphery of the first optical guide 210 and corresponds to the first optical guide 430, and the first optical guide 411 is connected to the first annular groove 210 by the first optical guide 311, and the first optical guide 430 forms an optical path for scattering light path to the first optical guide 311; the second light guide member 420 includes a second light path 421 disposed at an inner circumference of the second ring groove 220 and corresponding to a second end of the fourth light guide member 440, the second light path 421 being connected to the second light source 312, a reaction unit for guiding light injected into the second light path 421 by the second light source 312 to the second ring groove 220 to form scattered light, to be guided to the second detection member 322 by the fourth light guide member 440, the light detection function of the reaction unit of the second ring groove 220 is realized. Because the first detecting piece 321 and the second detecting piece 322 are far away from the accommodating space, the influence of the incubation temperature of the carrier plate 200 on the first detecting piece 321 and the second detecting piece 322 is avoided, and the detection accuracy is ensured. Meanwhile, since the second end of the third light guide 430 and the second end of the fourth light guide 440 are disposed in the accommodating space, the size of the tray 200 is not oversized, and the manipulation accuracy of the tray 200 is ensured.
In some alternative embodiments, the optical path module provided by the present application further includes a fifth light guide 450 and a sixth light guide 460;
the fifth light guide 450 and the sixth light guide 460 are disposed in the receiving space;
The fifth light guide 450 has a third light path 451 corresponding to the first light path 411, the third light path 451 is connected to the second end of the third light guide 430, and the third light path 451 forms a preset angle with the optical axis of the outgoing light of the first light path 411;
the sixth light guide 460 has a fourth light path 461 corresponding to the second light path 421, the fourth light path 461 is connected to the second end of the fourth light guide 440, and a predetermined angle is formed between the fourth light path 461 and the optical axis of the outgoing light of the second light path 421.
The other end of the third light path channel 451 corresponds to the first annular groove 210 at intervals between the first light path channels 411, and a preset angle is formed between the third light path channel 451 and the optical axis of the emergent light of the first light path channel 411, so that the light emitted by the first light path channel 411 irradiates the reaction unit of the first annular groove 210 to form scattered light and then enters the third light path channel 451, and the scattered light is guided to the first detection piece 321 by the third light path channel 451, so that the light detection function of the reaction unit of the first annular groove 210 is realized.
The other end of the fourth light path channel 461 corresponds to the second annular groove 220 at intervals between the second light path channels 421, and a preset angle is formed between the fourth light path channel 461 and the optical axis of the emergent light of the second light path channel 421, so that the scattered light can enter the fourth light path channel 461 after being irradiated onto the reaction unit of the second annular groove 220 by the light emitted by the second light path channel 421, and then the scattered light is guided to the second detection piece 322 by the fourth light path channel 461, thereby realizing the light detection function of the reaction unit of the second annular groove 220. By setting the third optical path channel 451 and the fourth optical path channel 461 to be inclined, scattered light can be better guided, and detection accuracy can be further improved.
In some embodiments, the predetermined angle includes 10 degrees to 30 degrees, for example, the predetermined angle may be 15 °, 20 °, 25 °, or the like, which is not limited. Scattered light formed by irradiation of light onto the reaction unit is concentrated in an included angle range of 10 degrees to 30 degrees with the incident light, that is, the scattered light is stronger in the included angle range of 10 degrees to 30 degrees, so that the detection accuracy can be effectively improved.
Further, the third optical path 451 is gradually shifted upward from an end close to the first optical path 411 to an end far from the first optical path 411, and the fourth optical path 461 is gradually shifted upward from an end close to the second optical path 421 to an end far from the second optical path 421.
In the detection process, it is necessary to add a reagent and a sample to the reaction cell, and when the amounts of the reagent and the sample are sufficiently large, scattered light formed by irradiation of light to the reaction cell can be regarded as a cone shape centered on the optical axis of the incident light, and at this time, the third optical path channel 451 and the fourth optical path channel 461 can be located at arbitrary positions on the conical surfaces of the cones. When the amounts of the reagent and the sample are small, the first light path 411 and the second light path 421 are parallel to the horizontal plane, and the mixed solution composed of the reagent and the sample is deposited at the bottom of the reaction unit, at this time, the scattered light formed by the light irradiated onto the reaction unit is concentrated above the optical axis of the incident light, and the third light path 451 and the fourth light path 461 adopt an upturned design, so that the mixed solution is suitable for the situation of less mixed solution, the usage amount and the consumption amount of the reagent and the sample can be effectively reduced, and the cost is further controlled.
Further, the fifth light guide 450 is provided with a first reference light path 452 corresponding to the first light path 411, and the sixth light guide 460 is provided with a second reference light path 462 corresponding to the second light path 421;
The first reference optical path channel 452 is connected to the first reference detector 331;
The second reference light path 462 is connected to the second reference detector 332.
In practice, the first reference optical path 452 may guide scattered light formed by the first optical path 411 after being emitted to the reaction unit to the first reference detector 331, and the second reference optical path 462 may guide scattered light formed by the second optical path 421 after being emitted to the reaction unit to the second reference detector 332. The service life and stability of the light source part are monitored by the reference detection part, so that the detection accuracy is further improved.
Further, the first reference optical path channel 452 includes a first segment channel 453, a second segment channel 454, and a first reflector 455, and the second reference optical path channel 462 includes a third segment channel 463, a fourth segment channel 464, and a second reflector 465;
The first section channel 453 is connected to the first reference detector 331 through the second section channel 454:
The third segment of channel 463 is connected to the second reference detector 332 by a fourth segment of channel 464:
The first reflecting member 455 is disposed between the first and second stage channels 453 and 454 for reflecting the light incident to the first stage channel 453 to the second stage channel 454 and then to the first reference detecting member 331;
The second reflecting member 465 is disposed between the third channel 463 and the fourth channel 464 for reflecting the light incident to the third channel 463 to the fourth channel 464 and then to the second reference detecting member 332.
In practice, the first section channels 453 form a predetermined angle with the second section channels 454, and the third section channels 463 form a predetermined angle with the fourth section channels 464, preferably a right angle, so that the light can be guided to a designated position, and the first reference detecting element 331 and the second reference detecting element 332 can be conveniently arranged in position.
Further, the diameter of the first light path 411 is gradually reduced from the end close to the first light source 311 to the end far from the first light source 311, and the diameter of the second light path 421 is gradually reduced from the end close to the second light source 312 to the end far from the second light source 312. By gradually shrinking the light path channel, the light condensing effect of converging light is achieved, and the detection accuracy can be effectively improved.
In some possible embodiments, the respective optical path channels may also be designed in a gradually decreasing diameter structure, for example, the diameter of the first optical path channel 411 gradually decreases from the incident end to the exit end, or the diameter of the first optical path channel 411 gradually decreases from the incident end to the exit end.
Further, at least one first diaphragm 341 is disposed in the first optical path 411, and at least one second diaphragm 342 is disposed in the second optical path 421.
When in implementation, the diaphragm is in a ring shape, the center is provided with a hole, so that stray light at the edge can be blocked, only light at the center part can be transmitted, and the detection accuracy can be further improved.
Further, a first mounting groove 456 and a second mounting groove 457 are provided in the third optical path channel 451, the first mounting groove 456 being for mounting the first detecting member 321, the third mounting groove 466 being for mounting the first condensing lens;
a third mounting groove 466 and a fourth mounting groove 467 are provided in the fourth optical path passage 461, the third mounting groove 466 is used for mounting the second detecting piece 322, and the fourth mounting groove 467 is used for mounting the second condenser lens.
In implementation, the first mounting groove 456, the second mounting groove 457, the third mounting groove 466 and the fourth mounting groove 467 are all in a groove shape, the optical probe part of the first detecting member 321 can be embedded into the first mounting groove 456, the optical probe part of the second detecting member 322 can be embedded into the third mounting groove 466, and the first condensing lens and the second condensing lens can play a role in condensing light, so that light can be more concentrated onto the optical probe of the detecting member, and further the detection accuracy is improved.
In some embodiments, the condensing lens may be a single-sided convex lens or a double-sided convex lens, which can play a role in condensing light, and is not limited.
In a second aspect, the present application also provides a biochemical analyzer comprising:
The carrier plate 200, the carrier plate 200 is formed with a first ring groove 210 and a second ring groove 220, the first ring groove 210 and the second ring groove 220 are concentrically arranged, the first ring groove 210 is arranged at the periphery of the second ring groove 220, the first ring groove 210 and the second ring groove 220 are used for bearing a reaction unit, the reaction unit is used for mixing a sample and a reagent to react, and an accommodating space is arranged between the reaction unit on the first ring groove 210 and the reaction unit on the second ring groove 220;
A detecting assembly including a first detecting member 321 and a second detecting member 322, and
Such as the optical path module described above.
It will be clear to those skilled in the art that, for convenience and brevity of description, the structure and implementation principle of the biochemical analyzer described above may refer to the corresponding structure and implementation principle in the first embodiment, and will not be described in detail herein.
In some embodiments, the biochemical analyzer provided by the application further includes a carrier, the optical path module is mounted on the carrier, and a sample placement position (not shown), a reagent placement position (not shown) and a manipulator (not shown) may be further disposed on the carrier, where the sample placement position is used for placing a stored sample, the reagent placement position is used for placing a stored reagent, and the manipulator is used for adding the sample and the reagent into the reaction unit, and then driving the carrier 200 to rotate by a driving motor for detection.
The optical path module of the present application is applied to a biochemical analyzer, the optical path module comprises a first optical guide 410, a second optical guide 420, a third optical guide 430 and a fourth optical guide 440, the carrier 200 of the analyzer is provided with a first annular groove 210 and a second annular groove 220 which are concentric, the first annular groove 210 is arranged at the periphery of the second annular groove 220, the first annular groove 210 and the second annular groove 220 are used for carrying a reaction unit for mixing a sample and a reagent to react, an accommodating space is arranged between the reaction unit on the first annular groove 210 and the reaction unit on the second annular groove 220, a first end of the third optical guide 430 corresponds to the first detection element 321, a first end of the fourth optical guide 440 corresponds to the second detection element 322, a second end of the third optical guide 430 and a second end of the fourth optical guide 440 are both arranged in the accommodating space, the first end of the third optical guide 430 and the first end of the fourth optical guide 440 are far away from the accommodating space, the first optical guide 410 comprises a first channel 411 arranged at the periphery of the first optical guide 210 and corresponds to the first optical guide 430, and the first optical guide 411 is connected to the first annular groove 210 by the first optical guide 311, and the first optical guide 430 forms an optical path for scattering light path to the first optical guide 311; the second light guide member 420 includes a second light path 421 disposed at an inner circumference of the second ring groove 220 and corresponding to a second end of the fourth light guide member 440, the second light path 421 being connected to the second light source 312, a reaction unit for guiding light injected into the second light path 421 by the second light source 312 to the second ring groove 220 to form scattered light, to be guided to the second detection member 322 by the fourth light guide member 440, the light detection function of the reaction unit of the second ring groove 220 is realized. Because the first detecting piece 321 and the second detecting piece 322 are far away from the accommodating space, the influence of the incubation temperature of the carrier plate 200 on the first detecting piece 321 and the second detecting piece 322 is avoided, and the detection accuracy is ensured. Meanwhile, since the second end of the third light guide 430 and the second end of the fourth light guide 440 are disposed in the accommodating space, the size of the tray 200 is not oversized, and the manipulation accuracy of the tray 200 is ensured.
The foregoing description of the preferred embodiments of the utility model is not intended to be limiting, but rather is intended to cover all modifications, equivalents, and alternatives falling within the spirit and principles of the utility model.
Claims (10)
1. The utility model provides a light path module, is applied to on the biochemical analysis appearance, the biochemical analysis appearance is provided with rotatable carrier disc, its characterized in that, light path module includes first light guide piece, second light guide piece, third light guide piece and fourth light guide piece:
The carrier disc is provided with a first annular groove and a second annular groove which are concentric, the first annular groove is arranged at the periphery of the second annular groove, the first annular groove and the second annular groove are used for bearing a reaction unit, the reaction unit is used for mixing a sample with a reagent for reaction, and an accommodating space is arranged between the reaction unit on the first annular groove and the reaction unit on the second annular groove;
The first end of the third light guide piece is used for corresponding to the first detection piece, the first end of the fourth light guide piece is used for corresponding to the second detection piece, the second end of the third light guide piece and the second end of the fourth light guide piece are both arranged in the accommodating space, and the first end of the third light guide piece and the first end of the fourth light guide piece are far away from the accommodating space;
The first light guide piece comprises a first light path channel which is arranged at the periphery of the first annular groove and corresponds to the second end of the third light guide piece, the first light path channel is connected with a first light source and is used for guiding the light which is injected into the first light path channel by the first light source to the reaction unit of the first annular groove to form scattered light so as to be guided to the first detection piece by the third light guide piece;
the second light guide piece comprises a second light path channel which is arranged on the inner periphery of the second annular groove and corresponds to the second end of the fourth light guide piece, the second light path channel is connected with a second light source and is used for guiding light which is injected into the second light path channel by the second light source to the reaction unit of the second annular groove to form scattered light, so that the scattered light is guided to the second detection piece by the fourth light guide piece.
2. The light path module of claim 1, further comprising a fifth light guide and a sixth light guide;
the fifth light guide member and the sixth light guide member are disposed in the accommodation space;
The fifth light guide piece is provided with a third light path channel corresponding to the first light path channel, the third light path channel is connected with the second end of the third light guide piece, and a preset angle included angle is formed between the third light path channel and the optical axis of the emergent light of the first light path channel;
The sixth light guide piece is provided with a fourth light path channel corresponding to the second light path channel, the fourth light path channel is connected with the second end of the fourth light guide piece, and a preset angle included angle is formed between the fourth light path channel and the optical axis of the emergent light of the second light path channel.
3. The optical path module according to claim 2, wherein the third optical path is gradually upwardly offset from an end close to the first optical path to an end far from the first optical path, the fourth optical path passage is gradually upwardly offset from an end close to the second optical path passage to an end far from the second optical path passage.
4. The optical path module of claim 2 or 3 wherein the predetermined angular included angle comprises 10 degrees to 30 degrees.
5. The light path module of claim 2, wherein the fifth light guide is provided with a first reference light path channel corresponding to the first light path channel, and the sixth light guide is provided with a second reference light path channel corresponding to the second light path channel;
the first reference light path channel is connected with a first reference detection piece;
The second reference light path channel is connected with a second reference detection piece.
6. The optical path module of claim 5 wherein the first reference optical path channel comprises a first segment channel, a second segment channel, and a first reflector, and wherein the second reference optical path channel comprises a third segment channel, a fourth segment channel, and a second reflector;
The first section channel is connected with the first reference detection piece through the second section channel:
The third section channel is connected with the second reference detection piece through the fourth section channel:
The first reflecting piece is arranged between the first section channel and the second section channel and is used for reflecting light entering the first section channel to the second section channel and then emitting the light to the first reference detecting piece;
The second reflecting piece is arranged between the third section channel and the fourth section channel and is used for reflecting light entering the third section channel to the fourth section channel and then emitting the light to the second reference detecting piece.
7. The optical path module as claimed in claim 1, wherein the diameter of the first optical path channel is tapered from an end closer to the first light source to an end farther from the first light source, and the diameter of the second optical path channel is tapered from an end closer to the second light source to an end farther from the second light source.
8. The optical path module according to claim 1 or 7, wherein at least one first aperture is provided in the first optical path and at least one second aperture is provided in the second optical path.
9. The optical path module according to claim 2, wherein a first mounting groove and a second mounting groove are provided in the third optical path channel, the first mounting groove being for mounting the first detecting member, the second mounting groove being for mounting a first condensing lens;
A third mounting groove and a fourth mounting groove are formed in the fourth light path channel, the third mounting groove is used for mounting the second detection piece, and the fourth mounting groove is used for mounting the second condensing lens.
10. A biochemical analyzer, comprising:
The carrier disc is provided with a first annular groove and a second annular groove which are concentrically arranged, the first annular groove is arranged on the periphery of the second annular groove, the first annular groove and the second annular groove are used for bearing a reaction unit, the reaction unit is used for mixing a sample with a reagent for reaction, and an accommodating space is reserved between the reaction unit on the first annular groove and the reaction unit on the second annular groove;
A detection assembly including a first detection member and a second detection member, and
The light path module of any one of claims 1 to 9.
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CN202420621977.4U CN222379713U (en) | 2024-03-28 | 2024-03-28 | Optical path module and biochemical analyzer |
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CN202420621977.4U CN222379713U (en) | 2024-03-28 | 2024-03-28 | Optical path module and biochemical analyzer |
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