Multi-temperature-zone medicine titration experiment device
Technical Field
The utility model relates to the technical field of pharmacokinetic experiments, in particular to a multi-temperature-zone drug titration experiment device.
Background
The medicine analysis is a subject for researching chemical examination, medicine stability, bioavailability, medicine clinical monitoring, qualitative and quantitative of effective components of Chinese herbal medicine and the like by using chemical, physical, biological and microbiological methods and technologies, and comprises chemical examination of finished medicine products, quality control of medicine production process, quality investigation of medicine storage process, clinical medicine analysis, in-vivo medicine analysis and the like.
In the prior art, in order to improve the efficiency of titration experiments, a drug analysis titrator is adopted to perform titration experiments, but the existing drug analysis titrator is low in efficiency when processing a plurality of drug analysis titration, and meanwhile, the temperature of the titration time cannot be selected according to requirements when the titration experiments are performed. For this purpose, a multi-temperature-zone drug titration experiment device is proposed.
Disclosure of utility model
The utility model aims to overcome the existing defects, provides a multi-temperature-zone medicine titration experimental device, can simultaneously perform multiple medicine analysis titrations, can adjust the titration temperature according to requirements during titration, improves the accuracy of experiments, and can effectively solve the problems in the background art.
In order to achieve the aim, the utility model provides the technical scheme that the multi-temperature-zone drug titration experiment device comprises a mounting plate and a storage component;
The front end of the circumferential surface of the mounting plate is fixed with a first mounting plate, the front side of the first mounting plate is provided with a display and a PLC controller, the upper end of the mounting plate is provided with a rotating assembly, and the lower end of the mounting plate is provided with a heating assembly;
The storage assembly comprises a storage barrel, a first outer toothed ring, an inner toothed ring, a second outer toothed ring, a mounting plate II, a first motor and a gear, wherein storage grooves which are uniformly distributed are formed in the edge of the mounting plate, the storage barrel is rotationally connected to the inside of the storage grooves, the first outer toothed ring is fixed on the circumferential surface of the storage barrel, the inner toothed ring is rotationally connected to the upper end of the mounting plate, the inner toothed ring is meshed with all the first outer toothed rings, the second outer toothed ring is fixed on the circumferential surface of the inner toothed ring, the mounting plate II is fixed at the right end of the circumferential surface of the mounting plate, the first motor is mounted on the upper side of the mounting plate, the gear is fixed on the output shaft of the first motor, the gear is meshed with the second outer toothed ring, the fastening assembly is mounted on the wall of the storage barrel, and the conical bottle required for titration experiments is stored by the storage assembly;
The input end of the PLC is electrically connected with the output end of an external power supply, the output end of the PLC is electrically connected with the input end of the first motor, and the PLC is electrically connected with the display in a bidirectional mode.
Further, rotating assembly includes second motor, pivot, linking bridge and go-between, the second motor is installed to the lower extreme of mounting disc, be fixed with the pivot on the output shaft of second motor, the upper end of pivot periphery is fixed with linking bridge, linking bridge's front side is fixed with the go-between, the go-between corresponds with the storage bucket of front side each other, the output of PLC controller is connected to the input electricity of second motor, drives the required buret of titration experiment through setting up rotating assembly and rotates.
Further, still include fixed subassembly, fixed subassembly includes threaded rod, rubber dish and carousel, threaded hole has been seted up to the front side of linking frame, the inside threaded connection of threaded hole has the threaded rod, the front end of threaded rod is fixed with the rubber dish, the rubber dish is located the inside of go-between, the rear end of threaded rod is fixed with the carousel, fixes the buret that titration experiment is required through setting up fixed subassembly.
Further, heating element includes electric heat ring and temperature sensor, evenly distributed's mounting groove has been seted up to the lower extreme of mounting disc, the mounting groove corresponds each other with the storage barrel, the internally mounted of mounting groove has the electric heat ring, the internally mounted of the storage tank that the mounting disc upper end was seted up has temperature sensor, the middle part of storage barrel begins to have the opening, temperature sensor is located open-ended inside, the output of PLC controller is connected to the input electricity of electric heat ring, temperature sensor is connected with outside PLC controller two-way electricity, heats the inside of storage barrel through setting up heating element.
Further, fastening component includes slide bar, connection pad, spring and arc fastening plate, evenly distributed's slide hole has been seted up on the periphery of storage barrel, the inside sliding connection of slide hole has the slide bar, the slide bar is fixed with the arc fastening plate on being located the terminal surface of storage barrel inside, the slide bar is fixed with the connection pad on being located the terminal surface of storage barrel outside, cup jointed the spring on the periphery of slide bar, the one end of spring is fixed on the periphery of storage barrel, the other end of spring is fixed on the terminal surface of connection pad, fixes the required erlenmeyer flask of titration experiment through setting up fastening component.
Further, the inside of go-between is fixed with the slipmat, the side of slipmat is fixed with evenly distributed's antislip strip, can guarantee buret's stability through setting up the slipmat.
Compared with the prior art, the utility model has the beneficial effects that:
1. The conical bottles used for experiments are stored through the storage barrel, the fastening assembly inside the storage barrel is used for fixing the conical bottles after storage, the connecting ring is connected with the burette used for the experiments after the fixing, the second motor is started after the fixing, so that the rotating shaft rotates to adjust the position of the burette, and the burette respectively titrates the liquid medicines in the conical bottles inside all the storage barrels in the adjusting process, so that multiple medicine analysis titrations can be completed under the condition, and the efficiency of the experiments is greatly improved;
2. The first motor is arranged to enable the titration device to start to drive the gear to rotate after titration, the gear rotates to drive the second outer toothed ring and the inner toothed ring to rotate, and the inner toothed ring rotates to drive all the storage barrels to rotate, so that the titrated liquid medicine and the liquid medicine in the conical bottle inside the storage barrel can be fully mixed under the condition, and the experiment can be completed by watching the reaction after mixing, so that the titration device is very convenient;
3. Through setting up heating element and making can be according to the inside that needs among each storage barrel according to the demand respectively input PLC controller before titration experiments, then start all electric heat ring respectively and heat the inside of all storage barrels, the in-process that heats is located the inside temperature sensor of storage barrel will detect each inside temperature of storage barrel, the PLC controller will self-closing all electric heat ring after the temperature numerical value that detects is the same with the numerical value that PLC controller inside stored, can observe the effect of experiment in the temperature of difference under such circumstances when titration experiments, the precision of experiment has been improved greatly.
Drawings
FIG. 1 is a schematic view of the front side structure of the present utility model;
FIG. 2 is a left side cross-sectional view of the present utility model;
FIG. 3 is an enlarged view of the utility model at A;
Fig. 4 is a schematic structural view of a fixing assembly according to the present utility model.
In the figure, a mounting plate 1, a mounting plate 2, a display 3, a PLC 4, a storage component 5, a storage barrel 51, a first outer toothed ring 52, an inner toothed ring 53, a second outer toothed ring 54, a second mounting plate 55, a first motor 56, a gear 57, a rotating component 6, a second motor 61, a rotating shaft 62, a connecting frame 63, a connecting ring 64, a fixing component 7, a threaded rod 71, a rubber disk 72, a rotary disk 73, a heating component 8, an electric heating ring 81, a temperature sensor 82, a fastening component 9, a sliding rod 91, a connecting disk 92, a spring 93, an arc-shaped fastening plate 94 and an anti-skid pad 10 are arranged.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-4, the present embodiment provides a multi-temperature-zone drug titration experiment apparatus, which includes a mounting plate 1 and a storage assembly 5;
the front end of the circumferential surface of the mounting plate 1 is fixedly provided with a mounting plate I2, the front side of the mounting plate I2 is provided with a display 3 and a PLC controller 4, the upper end of the mounting plate 1 is provided with a rotating assembly 6 to drive a burette required by a titration experiment to rotate, and the lower end of the mounting plate 1 is provided with a heating assembly 8;
The rotating assembly 6 comprises a second motor 61, a rotating shaft 62, a connecting frame 63 and a connecting ring 64, the second motor 61 is installed at the lower end of the mounting disc 1, the rotating shaft 62 is fixed on an output shaft of the second motor 61, the connecting frame 63 is fixed at the upper end of the circumferential surface of the rotating shaft 62, the connecting ring 64 is fixed at the front side of the connecting frame 63, the connecting ring 64 corresponds to the front storage barrel 51, and the input end of the second motor 61 is electrically connected with the output end of the PLC controller 4;
the titration tube fixing device is characterized by further comprising a fixing component 7 for fixing a burette required by a titration experiment, wherein the fixing component 7 comprises a threaded rod 71, a rubber disc 72 and a rotary disc 73, a threaded hole is formed in the front side of the connecting frame 63, the threaded rod 71 is connected with the inside of the threaded hole in a threaded manner, the rubber disc 72 is fixed at the front end of the threaded rod 71, the rubber disc 72 is positioned in the connecting ring 64, and the rotary disc 73 is fixed at the rear end of the threaded rod 71;
The heating assembly 8 comprises an electric heating ring 81 and a temperature sensor 82, wherein the lower end of the mounting plate 1 is provided with uniformly distributed mounting grooves, the mounting grooves correspond to the storage barrel 51, the electric heating ring 81 is arranged in the mounting grooves, the temperature sensor 82 is arranged in the storage groove formed in the upper end of the mounting plate 1, an opening is formed in the middle of the storage barrel 51, the temperature sensor 82 is positioned in the opening, the input end of the electric heating ring 81 is electrically connected with the output end of the PLC controller 4, the temperature sensor 82 is electrically connected with the external PLC controller 4 in a bidirectional manner, and the heating assembly 8 is arranged to heat the interior of the storage barrel 51;
wherein the storage component 5 comprises a storage barrel 51, a first outer gear ring 52, an inner gear ring 53, a second outer gear ring 54, a second mounting plate 55, a first motor 56 and a gear 57, wherein the edge of the mounting plate 1 is provided with uniformly distributed storage grooves, the storage barrel 51 is rotatably connected in the storage grooves, the first outer gear ring 52 is fixed on the circumferential surface of the storage barrel 51, the inner gear ring 53 is rotatably connected at the upper end of the mounting plate 1, the inner gear ring 53 is meshed with all the first outer gear rings 52, the second outer gear ring 54 is fixed on the circumferential surface of the inner gear ring 53, the second mounting plate 55 is fixed at the right end of the circumferential surface of the mounting plate 1, the first motor 56 is mounted on the upper side of the second mounting plate 55, the gear 57 is fixed on the output shaft of the first motor 56, the gear 57 is meshed with the second outer gear ring 54, the wall of the storage barrel 51 is provided with a fastening component 9, the fastening component 9 comprises a sliding rod 91, a connecting disc 92, a spring 93 and an arc fastening plate 94, the circumferential surface of the storage barrel 51 is provided with evenly distributed sliding holes, the sliding rod 91 is connected inside the sliding holes in a sliding mode, the arc fastening plate 94 is fixed on the end face of the sliding rod 91, which is located inside the storage barrel 51, the connecting disc 92 is fixed on the end face of the sliding rod 91, the circumferential surface of the sliding rod 91 is sleeved with the spring 93, one end of the spring 93 is fixed on the circumferential surface of the storage barrel 51, the other end of the spring 93 is fixed on the end face of the connecting disc 92, conical bottles required by titration experiments are fixed through the fastening component 9, and conical bottles required by the titration experiments are stored through the storage component 5;
Wherein the input end of the PLC controller 4 is electrically connected with the output end of an external power supply, the output end of the PLC controller 4 is electrically connected with the input end of the first motor 56, and the PLC controller 4 is electrically connected with the display 3 in a bidirectional manner.
Wherein, the anti-slip pad 10 is fixed in the connecting ring 64, the anti-slip strips which are uniformly distributed are fixed on the side surface of the anti-slip pad 10, and the stability of the burette can be ensured by arranging the anti-slip pad 10.
The working principle of the utility model is as follows:
Firstly, the required temperature values in each storage barrel 51 can be respectively input into the PLC controller 4 according to requirements, conical bottles used for experiments are placed into each storage barrel 51 one by one, the storage barrels 51 are fixed under the action of springs 93 adjacent to the conical bottles, all electric heating rings 81 are respectively started to heat the interiors of all the storage barrels 51 after the storage barrels are placed, the temperature sensor 82 positioned in the storage barrels 51 in the heating process detects the temperature in each storage barrel 51, the PLC controller 4 automatically closes all the electric heating rings 81 after the detected temperature values are the same as the values stored in the PLC controller 4, then a buret is inserted into the connecting rings 64, the threaded rod 71 is rotated after the buret is inserted, the rubber disc 72 is moved forwards to fix the buret, the second motor 61 is started after the rotation of the rotation shaft 62 to adjust the positions of the buret, and the buret is respectively titrated in the conical bottles in all the storage barrels 51 in the adjusting process, so that a plurality of medicine analyses can be completed under the conditions;
after titration, the first motor 56 is started to drive the gear 57 to rotate, the gear 57 rotates to drive the east-to-east second outer toothed ring 54 and the inner toothed ring 53 to rotate, the inner toothed ring 53 rotates to drive all the first outer toothed rings 52 to rotate, and all the first outer toothed rings 52 rotate to drive all the storage barrels 51 to rotate, so that the titrated liquid medicine and the liquid medicine in the conical bottle inside the storage barrels 51 can be fully mixed under the condition, and the experiment can be completed by watching the reaction after mixing, and the method is very convenient.
It should be noted that, the specific model of the PLC controller 4 disclosed in the above embodiment is siemens S7-200, the display 3 may be an SC170-NGCM embedded display, the first motor 56 and the second motor 61 may be 1LE0003 three-phase asynchronous motors, the electrothermal ring 81 may be a BK nicr electrothermal wire, the temperature sensor 82 may be a LSCI-TZ03 laser focusing infrared temperature sensor, and the control switch set controls the operation of the first motor 56, the second motor 61 and the electrothermal ring 81 by a method commonly used in the prior art.
The foregoing description is only illustrative of the present utility model and is not intended to limit the scope of the utility model, and all equivalent structures or equivalent processes or direct or indirect application in other related technical fields are included in the scope of the present utility model.