CN221918007U - Multiple sealed disposable biological reaction bag - Google Patents

Abstract

The utility model discloses a multi-seal disposable biological reaction bag which comprises a bagging and a lower bag body, wherein the lower bag body is arranged at the bottom end of the interior of the bagging, a containing cavity is formed in the interior of the lower bag body, the upper bag body is arranged at the top end of the interior of the bagging, a separation strip is arranged between the upper bag body and the lower bag body, and three groups of rectangular bags are fixedly welded between two sides of the interior of the upper bag body. This multiple sealed disposable biological reaction bag is unsettled through being provided with the locating piece on the outside top of cover bag, and the inside last bag body of cover bag divide into three sets of rectangle bags that can make parallel test, pulls out the sealing plug, and the rubber tube that can connect the guide mouth respectively is to rectangle bag injection reaction liquid, and the sealing plug is closed and the bolt is twisted, is fixed through preforming extrusion rubber tube in the slot, and the accommodation chamber in the lower bag body then uses as single pocket, takes out the rope extrusion inlet pipe of taking out of tensioning solid cover top both ends, has solved the not good problem of sealing performance.

Description

A multiple-sealed disposable bioreactor bag

Technical Field

The utility model relates to the technical field of bioreactor bags, in particular to a multiple-sealed disposable bioreactor bag.

Background Art

A bioreactor bag is a disposable product that can be filled with biological sample pre-liquid, bacterial solution, and reaction reagents. It is usually made of a transparent plastic film bag with a thicker texture than ordinary packaging materials to prevent leakage of internal juice. However, the storage space inside an ordinary bioreactor bag is relatively single, and the same reagent cannot be filled multiple times for parallel experiments. It is difficult to obtain accurate data due to the lack of comparison of the results. In addition, the sealing performance is poor, and the gas and heat produced by the internal bacteria can easily push open the stopper, causing the bag to leak and pollute the surrounding environment.

Now, a novel multi-sealed disposable bioreactor bag is proposed to solve the above problems.

Utility Model Content

The utility model aims to provide a disposable bioreactor bag with multiple seals to solve the problem of poor sealing performance in the above-mentioned background technology.

To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a multi-sealed disposable bioreactor bag, comprising a cover bag and a lower bag body, the lower bag body is installed at the bottom end of the cover bag, and a accommodating chamber is arranged inside the lower bag body, the upper bag body is installed at the top end of the cover bag, and a dividing strip is arranged between the upper bag body and the lower bag body, three groups of rectangular bags are fixedly welded between the two sides of the upper bag body, and a flat groove is arranged inside the rectangular bag, a positioning block is suspended at the top end of the outside of the cover bag, and three groups of slots are arranged between the two sides of the inside of the positioning block, the front end of the slot is movably connected with a pressing sheet, and the front of the pressing sheet is threadedly connected with a bolt, the top of the rectangular bag passes through the cover bag and is fixedly connected with a rubber tube, and a sealing plug is inserted at the top of the rubber tube.

Preferably, the pressing sheet is located at the front end of the rubber tube, and the pressing sheet can slide back and forth inside the slot along with the bolt.

Preferably, a feed pipe is fixedly connected to the right side of the rear of the lower bag body through the bag, and a fastening sleeve is installed on the outside of the bag for the feed pipe, a drawstring is sleeved between the two ends of the fastening sleeve, and a plug is inserted on the right side of the feed pipe.

Preferably, the rectangular bags are arranged at equal intervals inside the upper bag body, and the flat grooves are connected to the external rubber tube through the material guide port.

Preferably, an air inlet hole is reserved on the right side of the top of the upper bag body, and a dustproof block is inserted in the air inlet hole.

Preferably, the dust-proof block is located above the inside of the air inlet, and the dust-proof block and the air inlet are arranged in concentric circles.

Preferably, two plastic sheets are fixed to the front and rear ends of the exterior of the bag respectively, and a groove is provided on the surface of the plastic sheet, a patch is movably hinged inside the groove, and a silicone pad is provided under the patch.

Preferably, the patch is installed and fixed in the groove via a spring shaft, and the patch and the plastic sheet are in a vertical state of 90 degrees.

Compared with the prior art, the utility model has the following beneficial effects: the multi-sealed disposable bioreactor bag not only improves the sealing effect of the bag body and prevents the bag body from being damaged, but also maintains the bag body standing on the table;

(1) A positioning block is suspended at the top of the outer bag, and the upper bag body inside the bag is divided into three groups of rectangular bags for parallel testing. After the sealing plug is removed, the reaction liquid can be injected into the rectangular bags through the rubber tubes connected to the feed ports, and then the sealing plug is closed and the bolts are turned. The rubber tube is squeezed inside the slot by pressing the sheet to fix it. The accommodating chamber in the lower bag body is used as a single bag. After adding the reagent, the drawstrings at both ends of the top of the tightening sleeve are pulled and the feed tube is squeezed by tying a knot to prevent liquid leakage, thereby enriching the use functions inside the bioreactor bag.

(2) An air inlet is reserved on the right side of the top of the upper bag body. After the bacterial solution, reagents and other materials are bagged, the dust block plugged into the air inlet is opened, and the pipeline of the external air pump is connected to it, and the air is continuously flushed into the bag. The air will expand the gap between the lower bag body, the upper bag body and the bag, so that a bulging air bag is formed from all sides to protect the internal reagents from being damaged by external objects and flowing out. The thickened reaction bag can prevent the bag body from being damaged;

(3) By fixing two plastic sheets at the front and rear ends of the bag, the filled bag is placed upright on the table, and the hinged patches are broken out from the plastic sheets at the four corners. The patches are adhered to the table through the silicone pads installed on the surface of the bag. The plastic sheet and the patches are maintained in a vertical state under the connection of the spring shaft inside the plastic sheet. The temperature of the bag is maintained at both ends, so that people can directly observe the changes in the liquid filled inside the bag and obtain comparative results.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG1 is a schematic diagram of a front cross-sectional structure of the utility model;

FIG2 is a schematic diagram of the front cross-sectional structure of the positioning block of the utility model;

FIG3 is a schematic diagram of an enlarged partial cross-section structure of the utility model at A in FIG1;

FIG. 4 is a schematic diagram of the side cross-sectional structure of the bagging of the present invention.

In the figure: 1. bag; 2. lower bag body; 3. accommodating chamber; 4. feeding pipe; 5. plastic sheet; 6. dividing strip; 7. upper bag body; 8. rectangular bag; 9. flat groove; 10. plug; 11. rubber tube; 12. positioning block; 13. sealing plug; 14. slot; 15. bolt; 16. guide port; 17. dust block; 18. air inlet; 19. pressing sheet; 20. drawstring; 21. fastening sleeve; 22. groove; 23. patch; 24. silicone pad.

DETAILED DESCRIPTION

The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

Embodiment 1: Please refer to Figures 1-4, a multi-sealed disposable bioreactor bag, including a cover bag 1 and a lower bag body 2, the lower bag body 2 is installed at the bottom end of the cover bag 1, and the lower bag body 2 is provided with a accommodating chamber 3, the upper bag body 7 is installed at the top end of the cover bag 1, and a dividing strip 6 is provided between the upper bag body 7 and the lower bag body 2, three groups of rectangular bags 8 are fixedly welded between the two sides of the upper bag body 7, and the rectangular bags 8 are provided with flat grooves 9, a positioning block 12 is suspended at the top end of the outer side of the cover bag 1, and three groups of slots 14 are provided between the two sides of the positioning block 12, the front end of the slot 14 is movably connected with a pressing sheet 19, and the front of the pressing sheet 19 is threadedly connected with a bolt 15, the top of the rectangular bag 8 passes through the cover bag 1 and is fixedly connected with a rubber tube 11, and a sealing plug 13 is inserted at the top of the rubber tube 11, the pressing sheet 19 is located at the front end of the rubber tube 11, and the pressing sheet 19 can slide back and forth inside the slot 14 with the bolt 15;

The right side of the rear of the lower bag body 2 passes through the bag 1 and is fixedly connected with a feed pipe 4, and a fastening sleeve 21 is installed on the outside of the bag 1. A drawstring 20 is sleeved between the two ends of the inside of the fastening sleeve 21. A plug 10 is inserted on the right side of the feed pipe 4. The rectangular bags 8 are arranged at equal intervals inside the upper bag body 7. The flat grooves 9 are connected to the external rubber tube 11 through the guide port 16.

Specifically, as shown in Figures 1 and 2, the upper bag body 7 inside the bag 1 is divided into three groups of rectangular bags 8 that can be used for parallel tests. After the sealing plug 13 is pulled out, the reaction liquid can be injected into the rectangular bags 8 through the rubber tubes 11 connected to the material guide port 16, and then the sealing plug 13 is closed and the bolt 15 is turned. The rubber tube 11 is squeezed and fixed inside the slot 14 by the pressing piece 19. The accommodating chamber 3 in the lower bag body 2 is used as a single bag. Similarly, after adding the reagent, the drawstrings 20 at both ends of the top of the fastening sleeve 21 are pulled and the feed tube 4 is squeezed by tying a knot to prevent liquid leakage.

Embodiment 2: An air inlet hole 18 is reserved on the right side of the top of the upper bag body 7, and a dust block 17 is inserted in the air inlet hole 18. The dust block 17 is located above the inside of the air inlet hole 18, and the dust block 17 and the air inlet hole 18 are arranged in concentric circles;

Specifically, as shown in Figures 1 and 3, after the bacterial liquid, reagents and the like are bagged, the dustproof block 17 inserted in the air inlet 18 is opened, the pipeline of the external air pump is connected to it, and the air is continuously flushed into the inside of the bag 1. The air will expand the gap between the lower bag body 2, the upper bag body 7 and the bag 1, so as to form a bulging air bag from all sides to protect the internal reagents from being damaged by external objects and flowing out.

Embodiment 3: Two plastic sheets 5 are fixed at the front and rear ends of the bag 1, and the surface of the plastic sheet 5 is provided with a groove 22, and a patch 23 is movably hinged inside the groove 22, and a silicone pad 24 is provided below the patch 23. The patch 23 is fixed in the groove 22 through a spring shaft, and the patch 23 and the plastic sheet 5 are in a vertical state of 90 degrees;

Specifically, as shown in Figures 1 and 4, the filled bag 1 is placed upright on the table, the hinged patches 23 are broken out from the plastic sheets 5 at the four corners, and are adhered to the table through the silicone pads 24 installed on the surface of the object. Under the connection of the spring axis inside the plastic sheet 5, the plastic sheet 5 and the patch 23 are maintained in a vertical state, and the temperature of the object is maintained at both ends of the bag 1, so that people can directly observe the changes in the liquid filled inside the object.

Working principle: When the utility model is in use, the upper bag body 7 inside the bagging 1 is divided into three groups of rectangular bags 8 that can be used for parallel tests. The sealing plug 13 is pulled out, and the reaction liquid can be injected into the rectangular bag 8 through the rubber tube 11 connected to the material guide port 16, and then the sealing plug 13 is closed and the bolt 15 is turned. The rubber tube 11 is squeezed and fixed inside the slot 14 by the pressing piece 19. The accommodating chamber 3 in the lower bag body 2 is used as a single bag. Similarly, after adding the reagent, the drawstrings 20 at both ends of the top of the fastening sleeve 21 are pulled and the feed tube 4 is squeezed in a knotted and tied manner to prevent liquid leakage. After the bacterial liquid, reagents, etc. are bagged, the dust block inserted inside the air inlet 18 is opened. 17. Connect the pipeline of the external air pump to it and continuously flush the inside of the bag 1. The air will expand the gaps between the lower bag body 2, the upper bag body 7 and the bag 1, so as to form a bulging air bag from all sides to protect the internal reagent from being damaged by external objects and flowing out. Finally, place the bag 1 upright on the table, break out the hinged patch 23 from the plastic sheet 5 at the four corners, and make it sticky and contact with the table through the silicone pad 24 installed on the surface of the object. Under the connection action of the spring shaft inside the plastic sheet 5, the plastic sheet 5 and the patch 23 are maintained in a vertical state, and the temperature of the object is maintained at both ends of the bag 1, so that people can directly observe the changes of the liquid filled inside the object.

It is obvious to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be regarded as exemplary and non-limiting from any point of view, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims are included in the present invention. Any reference numeral in a claim should not be regarded as limiting the claim to which it relates.

Claims (8)

1. The utility model provides a disposable biological reaction bag of multiple seal, includes cover bag (1) and lower bag body (2), its characterized in that: the utility model discloses a sealing plug, including cover bag (1), lower bag body (2) are installed to the inside bottom of cover bag (1), and the inside of lower bag body (2) is provided with holds cavity (3), bag body (7) are installed on the inside top of cover bag (1), and go up and be provided with separate strip (6) between bag body (7) and lower bag body (2), fixed welding has three rectangular bag (8) between the inside both sides of cover bag body (7), and the inside of rectangular bag (8) is provided with flat groove (9), the unsettled locating piece (12) that is provided with in top of cover bag (1) outside, and be provided with three group slot (14) between the inside both sides of locating piece (12), the front end swing joint of slot (14) inside has preforming (19), and the place ahead threaded connection of preforming (19) has bolt (15), the top of rectangular bag (8) is passed cover bag (1) fixedly connected with rubber tube (11), and sealing plug (13) are installed at the top of rubber tube (11).

2. A multi-sealed disposable bioreactor bag according to claim 1, wherein: the pressing piece (19) is positioned at the front end of the rubber tube (11), and the pressing piece (19) can slide back and forth along with the bolt (15) in the slot (14).

3. A multi-sealed disposable bioreactor bag according to claim 1, wherein: the right side at lower bag body (2) rear passes cover bag (1) fixedly connected with inlet pipe (4), and inlet pipe (4) are installed in the outside of cover bag (1) and are fastened cover (21), pull rope (20) have been cup jointed between the inside both ends of fastening cover (21), chock (10) have been installed on the right side of inlet pipe (4).

4. A multi-sealed disposable bioreactor bag according to claim 3, wherein: the rectangular bags (8) are arranged at equal intervals in the upper bag body (7), and the flat grooves (9) are communicated with the outer rubber tube (11) through the material guide opening (16).

5. A multi-sealed disposable bioreactor bag according to claim 1, wherein: an air inlet hole (18) is reserved on the right side of the top of the upper bag body (7), and a dustproof block (17) is inserted into the air inlet hole (18).

6. A multi-sealed disposable bioreactor bag according to claim 5, wherein: the dustproof blocks (17) are positioned above the inside of the air inlet holes (18), and the dustproof blocks (17) and the air inlet holes (18) are arranged in concentric circles.

7. A multi-sealed disposable bioreactor bag according to claim 1, wherein: two plastic sheets (5) are respectively fixed at the front end and the rear end of the outer part of the bagging (1), grooves (22) are formed in the surfaces of the plastic sheets (5), patches (23) are movably hinged in the grooves (22), and silica gel pads (24) are arranged below the patches (23).

8. A multi-sealed disposable bioreactor bag according to claim 7, wherein: the patch (23) is fixedly arranged in the groove (22) through a spring shaft, and the patch (23) and the plastic sheet (5) are in a ninety-degree vertical state.