CN221405710U - Incubation assembly and fluorescence immunoassay analyzer - Google Patents

Abstract

The embodiment of the utility model provides an incubation component and a fluorescent immunoassay analyzer, which relate to the field of in vitro diagnostic auxiliary equipment. The incubation component provided by the embodiment of the utility model includes an incubation plate, a reagent card fixing part and an in-place detection part. The in-place detection part assists the reagent card fixing part to strengthen the fixation of the reagent card. The incubation component has the characteristics of simple structure and good stability.

Description

Incubation components and fluorescent immunoassay analyzer

CROSS-REFERENCE TO RELATED APPLICATIONS

The present disclosure claims the priority of Chinese patent application number 2023103121717, filed with the Chinese Patent Office on March 27, 2023, and entitled “Fluorescent Immunoassay Analyzer”; the entire contents of which are incorporated by reference into the present disclosure.

Technical Field

The present application relates to the field of in vitro diagnostic auxiliary equipment, and in particular to an incubation component and a fluorescent immunoassay analyzer.

Background technique

When the fluorescent immunoassay analyzes the reagent card, the reagent card needs to be loaded onto a fixed structure for detection and incubation. The stability of the reagent card carrier in the incubation component affects the performance of the instrument.

The inventors have discovered that the fixing structure of the fluorescence instrument reagent card carrier in the incubation assembly currently on the market fails after a long period of use, resulting in the reagent card being unable to be effectively and stably fixed in the reagent card holding slot.

Utility Model Content

The utility model aims to provide an incubation component, which has the characteristics of simple structure and good stability, and can effectively assist and strengthen the fixing effect of the reagent card fixing part.

The utility model aims to provide a fluorescence analyzer, which includes the above-mentioned incubation component. The fluorescence analyzer also has the characteristics of simple structure and good stability, and can fix the reagent card long, effectively and stably.

The embodiment of the utility model is achieved as follows:

In a first aspect, the utility model provides an incubation component, comprising:

An incubation plate, wherein the incubation plate is provided with an incubation position and an incubation cavity for accommodating the reagent card;

A reagent card fixing member, the reagent card fixing member comprising a first elastic sheet arranged above the incubation position and a second elastic sheet arranged on one side of the incubation position, for pressing and fixing the reagent card placed in the incubation position;

The in-place detection member is used to detect whether the reagent card is inserted into a predetermined position of the incubation cavity.

In an optional embodiment, the incubation plate includes a base plate and a cover plate, the base plate forms a plurality of incubation positions, the plurality of incubation positions are arranged side by side in the left-right direction on the base plate for accommodating reagent cards, the cover plate is arranged on the base plate, and the base plate and the cover plate are combined to form an incubation cavity internally.

In an optional embodiment, the in-place detection member is a micro switch, and the micro switch is arranged on the side wall of the bottom of the incubation cavity. When the reagent card is inserted into the bottom of the incubation cavity, the side edge of the reagent card contacts and presses against the action contact of the micro switch, so that the fixed contact and the moving contact of the micro switch are quickly connected or disconnected, and a position signal of the reagent card being in place or out is received.

In an optional embodiment, the micro switch can apply a pressure directly to the reagent card when the reagent card is inserted, and the direction of the pressure is different from the extension direction of the reagent card when it is inserted and withdrawn, which can assist the second spring sheet in fixing the reagent card horizontally.

In an optional embodiment, the first elastic piece forms a first protrusion, and the first protrusion can be detachably contacted with the reagent card inserted into the incubation position.

In an optional embodiment, the first elastic sheets may be provided in two or more groups, distributed on both sides of the incubation position, and capable of pressing both sides of the reagent card inserted into the incubation position;

or,

The two groups of the first elastic sheets are connected as one body.

In an optional embodiment, the second elastic piece has a second protrusion, and the second protrusion can be detachably contacted with the reagent card inserted into the incubation position.

In an optional embodiment, a spring element receiving groove is provided on one side of the incubation position, and the second spring element is provided in the spring element receiving groove.

In an optional embodiment, a limiting convex strip is provided on the bottom of the incubation position, and the limiting convex strip extends along the movement direction of the reagent card inserted into the incubation position, and the reagent card can slidably cooperate with the limiting convex strip.

In a second aspect, the utility model provides a fluorescent immunoassay analyzer, comprising the incubation component described in any one of the aforementioned embodiments.

The beneficial effects of the embodiments of the utility model are as follows: the embodiments of the utility model provide an incubation component that effectively and stably fixes the reagent card, has the characteristics of simple structure and good stability, can effectively assist and strengthen the fixing effect of the reagent card fixing part, especially by giving the inserted reagent card a positive pressure, and the pressure direction is different from the derived direction of the reagent card insertion and withdrawal, thereby assisting the second spring sheet to fix the reagent card horizontally, solving the problem of the stability of the reagent card in the incubation component being affected by the failure of the reagent card fixing part.

BRIEF DESCRIPTION OF THE DRAWINGS

In order to more clearly illustrate the technical solutions of the embodiments of the utility model, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the utility model and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other relevant drawings can be obtained based on these drawings without paying creative work.

FIG1 is a schematic diagram of the structure of a fluorescent immunoassay analyzer provided in an embodiment of the present utility model;

FIG2 is a schematic structural diagram of an incubation component with a temperature-isolating cover hidden therein provided by an embodiment of the present invention;

FIG3 is a partial structural schematic diagram of an incubation component provided in an embodiment of the utility model;

FIG4 is a schematic diagram of the front structure of a reagent card provided in an embodiment of the present utility model;

FIG5 is a schematic diagram of the back structure of a reagent card provided in an embodiment of the present utility model;

FIG6 is a schematic structural diagram of a first spring sheet provided in an embodiment of the present utility model;

FIG7 is a schematic diagram of the structure of a second spring sheet provided in an embodiment of the present utility model;

FIG8 is a schematic diagram of the structure of the micro switch provided by the present invention.

Icons: 10-fluorescent immunoassay analyzer; 100-incubation component; 110-base plate; 120-incubation plate; 1211-bottom plate; 12111-incubation position; 1222-cover plate; 12221-scanning window; 1213-incubation cavity; 12131-limiting convex strip; 130-reagent card fixing member; 131-first spring piece; 1311-fixing part; 1312-first protruding part; 132-second spring piece; 1321-second protruding part; 1322-connecting end; 1323-spring piece receiving groove; 140-in-place detection member; 141-micro switch; 1411-action contact piece; 1412-trigger member; 20-reagent card; 21-reaction area; 22-guide channel.

Detailed ways

In order to make the purpose, technical solution and advantages of the embodiment of the utility model clearer, the technical solution in the embodiment of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiment of the utility model. Obviously, the described embodiment is a part of the embodiment of the utility model, not all of the embodiments. Generally, the components of the embodiment of the utility model described and shown in the drawings here can be arranged and designed in various different configurations.

Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the present invention to be protected, but merely represents selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, it does not require further definition and explanation in the subsequent drawings.

In the description of the present utility model, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inside", "outside", etc. indicate the orientation or position relationship based on the orientation or position relationship shown in the accompanying drawings, or the orientation or position relationship in which the utility model product is usually placed when in use, which is only for the convenience of describing the utility model and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present utility model. In addition, the terms "first", "second", "third", etc. are only used to distinguish the description, and cannot be understood as indicating or implying relative importance.

In addition, the terms "horizontal", "vertical" and the like do not mean that the components are required to be absolutely horizontal or suspended, but can be slightly tilted. For example, "horizontal" only means that its direction is more horizontal than "vertical", and does not mean that the structure must be completely horizontal, but can be slightly tilted.

In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

As disclosed in the background technology, when the fluorescent immunoassay analyzes the reagent card, the reagent card needs to be loaded onto a fixed structure for detection and incubation. The stability of the reagent card carrier in the incubation component affects the performance of the instrument. The inventors have found that the fixed structure of the fluorescent instrument reagent card carrier in the incubation component currently on the market fails after a long period of use, resulting in the problem that the reagent card cannot be effectively and stably fixed in the reagent card carrier slot.

In order to solve the above problems, the utility model provides a novel incubation component and a fluorescent immunoassay analyzer.

Based on this, the present invention will be described in detail with reference to the accompanying drawings and in combination with the embodiments. Please refer to Figures 1 and 2, Figure 1 is a schematic diagram of the structure of the fluorescent immunoassay analyzer 10 provided in the embodiment of the present invention, and Figure 2 is a schematic diagram of the structure of the incubation component 100 hidden behind the temperature insulation cover provided in the embodiment of the present invention. The fluorescent immunoassay analyzer 10 provided in the embodiment of the present invention outputs the test results by testing the reagent card 20 to which the sample to be analyzed is added. The fluorescent immunoassay analyzer 10 includes an incubation component 100, which firmly mounts the reagent card 20 for detection and incubation.

Please refer to Figures 1 to 4. The incubation component 100 includes a substrate 110 and an incubation plate 120. The incubation plate 120 includes a bottom plate 1211 and a cover plate 1222. The bottom plate 1211 forms a plurality of incubation positions 12111. The plurality of incubation positions 12111 are arranged side by side in the left-right direction on the bottom plate 1211 for accommodating a reagent card 20. The cover plate 1222 is arranged on the bottom plate 1211. A scanning window 12221 is provided on the cover plate 1222. The scanning window 12221 corresponds to the reaction area 21 of the reagent card 20 placed in the incubation position 12111, so that the photometric component can scan the reagent card 20 through the scanning window 12221. The bottom plate 1211 and the cover plate 1222 are combined to form an incubation cavity 1213 internally.

In order to ensure that the reagent card 20 can be stably inserted and fixed on the incubation position 12111, the incubation component 100 further includes a reagent card fixing member 130 disposed on the incubation position 12111. The reagent card fixing member 130 includes a first elastic piece 131 and a second elastic piece 132. The first elastic piece 131 is disposed above the incubation position 12111 to press the reagent card 20 inserted into the incubation cavity 1213 from above so that it is stably limited in the vertical direction.

Optionally, the first spring sheet 131 can be set as an elastic metal spring sheet, and the distance between the lowest point of the contact surface between the elastic metal spring sheet and the reagent card 20 and the bottom surface of the incubation cavity 1213 is smaller than the thickness of the reagent card 20, so that the first spring sheet 131 can apply vertical pressure to the reagent card 20 after the reagent card 20 is inserted.

As shown in Figs. 3 and 6, optionally, the first elastic piece 131 forms a first protrusion 1312, and the first protrusion 1312 can be detachably contacted with the reagent card 20 inserted into the incubation cavity 1213. The first protrusion 1312 abuts against the reagent card 20, which can minimize the contact area with the reagent card 20 and prevent the heat of the reagent card 20 from being conducted by the fixing member during incubation.

Optionally, two or more groups of first spring pieces 131 can be provided, distributed on both sides of the incubation cavity 1213, and can press both sides of the reagent card 20 inserted into the incubation cavity 1213. On the one hand, the reaction area 21 on the reagent card 20 can be avoided. At the same time, pressing on both sides simultaneously can improve the stability of the reagent card 20 being fixed and clamped.

Furthermore, the two groups of first spring pieces 131 can be connected as one body, including a fixed portion 1311 connected to both sides of the incubation cavity 1213, to form a pressing piece with two ends pressed together. This can avoid the situation where the first spring piece 131 is fixed on one side of the incubation cavity 1213, because the force point is only on the fixed end on one side. The lifting when the reagent card 20 is inserted makes the first spring piece 131 arranged on one side more likely to deform at the fixed end and cause failure. Compared with the pressing piece with two ends pressed together, since the first spring piece 131 is lifted when the reagent card 20 is inserted and has two force points on the left and right, the lifting force is more easily absorbed by the deformation of the first spring piece 131 itself, rather than causing damage to the spring piece close to the fixed end. This can improve the stability of the pressing of the first spring piece 131 and increase the service life of the spring piece.

Please refer to Figures 3 and 7. The second spring piece 132 is arranged on one side of the incubation cavity 1213, and the side is provided with a spring piece accommodating groove 1323. The second spring piece 132 is arranged in the spring piece accommodating groove 1323. The second spring piece 132 has a second protrusion 1321 and a connecting end 1322, wherein the connecting end 1322 is fixedly connected to one side of the incubation cavity 1213, and the second protrusion 1321 faces the incubation cavity 1213. The distance from the second protrusion 1321 to the other side of the incubation cavity 1213 is smaller than the distance of the groove of the reagent card 20, so that the inserted reagent card 20 can be abutted against the side.

Please refer to Fig. 3 and Fig. 5. The bottom wall of the incubation cavity 1213 is provided with a limiting convex strip 12131, which extends along the movement direction of the reagent card 20 inserted into the incubation cavity 1213. When the reagent card 20 cooperates with the incubation cavity 1213, the reagent card 20 and the limiting convex strip 12131 are slidably matched. Therefore, in the process of the reagent card 20 being inserted into or withdrawn from the incubation cavity 1213, the limiting convex strip 12131 plays a good guiding role in the sliding of the reagent card 20 relative to the incubation plate 120. At the same time, the limiting convex strip 12131 can cooperate with the guide channel 22 of the reagent card 20 to limit the position of the reagent card 20 in the incubation cavity 1213, and play an auxiliary role in the positioning of the reagent card 20, wherein the two ends of the limiting convex strip 12131 are arc-shaped, which is convenient for smooth sliding between the two.

Optionally, the incubation component 100 further includes a position detection member 140 for detecting whether the reagent card 20 is inserted or not inserted into a predetermined position of the incubation chamber 1213. Generally speaking, the position detection member 140 can be set as a micro switch 141, but is not limited thereto. The conventional features for detecting the position of an object that can be foreseen by those skilled in the art are all included in the present solution, such as using an optical coupling sensor, a displacement laser sensor, etc.

Please refer to Figure 8. The micro switch 141 includes an action contact 1411 and a trigger member 1412. The micro switch 141 is set in the incubation cavity 1213. The action contact 1411 of the micro switch 141 contacts the position of the sensing reagent card 20. As the reagent card 20 is inserted into the incubation cavity 1213, the trigger member 1412 is activated to detect whether it has reached the predetermined position of the incubation cavity 1213.

Please refer to Figure 3 again. The micro switch 141 is set at the bottom of the incubation cavity 1213 or the side wall of the bottom. Optionally, the micro switch 141 is set at the side wall of the bottom of the incubation cavity 1213. When the reagent card 20 is inserted into the bottom of the incubation cavity 1213, the reagent card 20 is guided by the action contact 1411 of the micro switch 141 to slide into the incubation cavity 1213, and the side contact presses the action contact 1411 of the micro switch 141, so that the fixed contact and the moving contact of the micro switch 141 are quickly connected or disconnected, and the position signal of the reagent card 20 in place or out is received. Different from setting the micro switch 141 at the bottom of the incubation cavity 1213, the micro switch 141 is set on the side wall of the bottom of the incubation cavity 1213. According to the reaction of the force, the micro switch 141 can give a pressure directly to the reagent card 20 when inserting the reagent card 20. The direction of the pressure is different from the extension direction of the reagent card 20 for insertion and withdrawal, and can assist the second spring piece 132 to fix the reagent card 20 horizontally.

Especially when the reagent card fixing part 130 has been used for a long time, the reagent card fixing part 130 may fail due to wear and fatigue, resulting in the problem that the reagent card 20 cannot be effectively and stably fixed in the reagent card 20 bearing slot. If the micro switch 141 is set at the bottom of the incubation cavity 1213, when it fails or the fixing effect of the reagent card fixing part 130 is poor, the elastic force of the micro switch 141 itself will push the reagent card 20 out, resulting in failure to detect. Fixing the micro switch 141 to the bottom side wall of the incubation cavity 1213 can not only detect whether the reagent card 20 has reached the bottom of the incubation cavity 1213, but also avoid the risk of the reagent card 20 being pushed out when the reagent card fixing part 130 fails or the fixing effect is poor. In addition, due to its side setting, it is also possible to provide positive pressure to the guide channel 22 of the reagent card 20 against the limiting convex strip 12131, and one side of the reagent card 20 against the side of the non-fixed second elastic sheet 132 of the incubation cavity 1213, thereby increasing the static friction between the two relative to the incubation cavity 1213, and providing the reagent card 20 fixing effect when the reagent card fixing part 130 is normally fixed and when the effect is poor or even fails. On the basis of realizing its original function, it avoids possible adverse consequences and brings a new technical effect of improving the fixing stability of the reagent card 20.

Taking this embodiment as an example, the working process and principle of the incubation component 100 and the fluorescent immunoassay analyzer 10 provided by the present invention are as follows:

When the fluorescence analyzer 10 tests the reagent card 20 to which the sample to be analyzed is added, the reagent card 20 is inserted into the incubation position 12111 of the incubation component 100, and the first spring piece 131 is arranged above the incubation position 12111, and the first spring piece 131 forms a first protrusion 1312, and the first protrusion 1312 abuts against the reagent card 20, thereby realizing the pressing from above of the reagent card 20 inserted into the incubation cavity 1213, so that it is stably limited in the vertical direction.

A spring receiving groove 1323 is provided on one side of the incubation cavity 1213 . The second spring 132 is disposed in the spring receiving groove 1323 and can abut against the side of the inserted reagent card 20 .

A limiting ridge 12131 is provided on the bottom wall of the incubation cavity 1213, and the limiting ridge 12131 extends along the movement direction of the reagent card 20 inserted into the incubation cavity 1213. At the same time, the limiting ridge 12131 can cooperate with the guide channel 22 of the reagent card 20 to limit the position of the reagent card 20 in the incubation cavity 1213, thereby assisting in positioning the reagent card 20.

The micro switch 141 is arranged on the side wall at the bottom of the incubation chamber 1213. When the reagent card 20 is inserted into the bottom of the incubation chamber 1213, the reagent card 20 is guided by the action contact piece 1411 of the micro switch 141 and slides into the incubation chamber 1213. The side contact presses the action contact piece 1411 of the micro switch 141, so that the fixed contact of the micro switch 141 is quickly connected or disconnected with the moving contact, and the position signal of the reagent card 20 being in place or leaving is received. At the same time, according to the reaction of the force, the micro switch 141 can give the inserted reagent card 20 a pressure directly against the reagent card 20, so as to assist the second elastic piece 132 to fix the reagent card 20 horizontally. In addition, the micro switch 141 can also provide positive pressure to the guide channel 22 of the reagent card 20 against the limiting convex strip 12131, and one side of the reagent card 20 against the side of the non-fixed second elastic sheet 132 of the incubation cavity 1213, thereby increasing the static friction between the two relative to the incubation cavity 1213.

In summary, the embodiment of the utility model provides an incubation component 100 that effectively and stably fixes the reagent card 20, which has the characteristics of simple structure and good stability. It can effectively assist and strengthen the fixing effect of the reagent card fixing part 130, and solves the problem of affecting the stability of the reagent card 20 in the incubation component 100 due to the failure of the reagent card fixing part 130.

The present invention also provides a fluorescent immunoassay analyzer 10, which includes the above-mentioned incubation component 100. Therefore, the technical effects achieved are basically the same as those described above, and will not be repeated here. The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various changes and variations. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention shall be included in the protection scope of the present invention.

Claims (10)

1. An incubation component, characterized in that it comprises: An incubation plate (120), wherein the incubation plate (120) is provided with an incubation position (12111) and an incubation cavity (1213) for accommodating the reagent card (20); A reagent card fixing member (130), the reagent card fixing member (130) comprising a first elastic piece (131) arranged above the incubation position (12111) and a second elastic piece (132) arranged on one side of the incubation position (12111), and used for pressing and fixing the reagent card (20) placed in the incubation position (12111); The in-place detection member (140) is used to detect whether the reagent card (20) is inserted into a predetermined position of the incubation cavity (1213). 2. The incubation component according to claim 1 is characterized in that the incubation plate (120) includes a base plate (1211) and a cover plate (1222), the base plate (1211) forms a plurality of incubation positions (12111), and the plurality of incubation positions (12111) are arranged side by side in the left-right direction on the base plate (1211) for accommodating the reagent card (20), the cover plate (1222) is arranged on the base plate (1211), and the base plate (1211) and the cover plate (1222) are combined to form the incubation cavity (1213) inside. 3. The incubation component according to claim 2 is characterized in that the in-place detection member (140) is a micro switch (141), and the micro switch (141) is arranged on the side wall of the bottom of the incubation cavity (1213). When the reagent card (20) is inserted into the bottom of the incubation cavity (1213), the side of the reagent card (20) contacts and presses the action contact (1411) of the micro switch (141), so that the fixed contact and the moving contact of the micro switch (141) are quickly connected or disconnected, and a position signal of the reagent card (20) being in place or leaving is received. 4. The incubation component according to claim 3 is characterized in that the micro switch (141) can apply a pressure directly to the reagent card (20) when inserting the reagent card (20), and the direction of the pressure is different from the extension direction of the insertion and withdrawal of the reagent card (20), which can assist the second spring sheet (132) to fix the reagent card (20) horizontally. 5. The incubation component according to claim 1 is characterized in that the first elastic piece (131) forms a first protrusion (1312), and the first protrusion (1312) can be detachably contacted with the reagent card (20) inserted into the incubation position (12111). 6. The incubation component according to claim 1, characterized in that the first spring pieces (131) can be provided in two or more groups, distributed on both sides of the incubation position (12111), and can press against both sides of the reagent card (20) inserted into the incubation position (12111); or, The two groups of the first elastic sheets (131) are integrally connected. 7. The incubation component according to claim 1 is characterized in that the second elastic piece (132) has a second protrusion (1321), and the second protrusion (1321) can be detachably contacted with the reagent card (20) inserted into the incubation position (12111). 8. The incubation component according to claim 7 is characterized in that a spring-loaded accommodating groove (1323) is provided on one side of the incubation position (12111), and the second spring (132) is provided in the spring-loaded accommodating groove (1323). 9. The incubation component according to any one of claims 1 to 8 is characterized in that a limiting convex strip (12131) is provided on the bottom of the incubation position (12111), and the limiting convex strip (12131) extends along the movement direction of the reagent card (20) when it is inserted into the incubation position (12111), and the reagent card (20) can slidably cooperate with the limiting convex strip (12131). 10. A fluorescent immunoassay analyzer, characterized in that it comprises the incubation component according to any one of claims 1 to 9.