CN219870574U - Sample processing device for mass spectrometry detection - Google Patents
Sample processing device for mass spectrometry detection Download PDFInfo
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- CN219870574U CN219870574U CN202322349836.XU CN202322349836U CN219870574U CN 219870574 U CN219870574 U CN 219870574U CN 202322349836 U CN202322349836 U CN 202322349836U CN 219870574 U CN219870574 U CN 219870574U
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- 238000004949 mass spectrometry Methods 0.000 title claims abstract description 27
- 238000012545 processing Methods 0.000 title claims abstract description 24
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- 238000007789 sealing Methods 0.000 claims abstract description 35
- 238000005070 sampling Methods 0.000 claims abstract description 27
- 239000007788 liquid Substances 0.000 claims description 63
- 238000001914 filtration Methods 0.000 claims description 10
- 239000011148 porous material Substances 0.000 claims description 3
- 230000006978 adaptation Effects 0.000 claims description 2
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims 1
- 235000017491 Bambusa tulda Nutrition 0.000 claims 1
- 241001330002 Bambuseae Species 0.000 claims 1
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims 1
- 239000011425 bamboo Substances 0.000 claims 1
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- 244000183685 Citrus aurantium Species 0.000 description 3
- 235000007716 Citrus aurantium Nutrition 0.000 description 3
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- DFPMSGMNTNDNHN-ZPHOTFPESA-N naringin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@H]1[C@H](OC=2C=C3O[C@@H](CC(=O)C3=C(O)C=2)C=2C=CC(O)=CC=2)O[C@H](CO)[C@@H](O)[C@@H]1O DFPMSGMNTNDNHN-ZPHOTFPESA-N 0.000 description 1
- 229940052490 naringin Drugs 0.000 description 1
- 229930019673 naringin Natural products 0.000 description 1
- ARGKVCXINMKCAZ-UZRWAPQLSA-N neohesperidin Chemical compound C1=C(O)C(OC)=CC=C1[C@H]1OC2=CC(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O[C@H]3[C@@H]([C@H](O)[C@@H](O)[C@H](C)O3)O)=CC(O)=C2C(=O)C1 ARGKVCXINMKCAZ-UZRWAPQLSA-N 0.000 description 1
- ARGKVCXINMKCAZ-UHFFFAOYSA-N neohesperidine Natural products C1=C(O)C(OC)=CC=C1C1OC2=CC(OC3C(C(O)C(O)C(CO)O3)OC3C(C(O)C(O)C(C)O3)O)=CC(O)=C2C(=O)C1 ARGKVCXINMKCAZ-UHFFFAOYSA-N 0.000 description 1
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- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
The utility model provides a sample processing device for mass spectrometry detection, which comprises a sampling assembly and an extraction assembly arranged below the sampling assembly, wherein the extraction assembly comprises a shielding outer sleeve, an extraction needle arranged in the shielding outer sleeve, the extraction needle comprises a connecting block, an extraction vertical pipe arranged on the connecting block and an extraction horizontal pipe arranged on the side surface of the connecting block, the extraction vertical pipe is communicated with the extraction horizontal pipe, the shielding outer sleeve is provided with a through hole matched with the extraction horizontal pipe, the sampling assembly comprises a sealing cover sleeved on the outer side of the shielding outer sleeve, a compression bar arranged on the sealing cover and a leakage quantitative pipe arranged below the sealing cover, the leakage quantitative pipe is sleeved outside the connecting block, and the bottom of the leakage quantitative pipe is provided with a cutting inclined plane. The sample processing device for mass spectrometry detection solves the problems that excessive pretreatment processes are complicated and time-consuming and loss and pollution are caused to samples when effective components of Chinese herbal medicine fructus aurantii are detected in the prior art.
Description
Technical Field
The utility model relates to the technical field of medical equipment, in particular to a sample processing device for mass spectrometry detection.
Background
The method comprises the steps of conventional medicinal material identification of fructus aurantii, grinding, sampling, adding a solvent, heating and refluxing, cooling, filtering, evaporating to dryness, dissolving, eluting by a column, filtering by a microporous filter membrane, and detecting by chromatography, wherein naringin in the analysis substance is not less than 4.0% and neohesperidin is not less than 3.0%, and the method belongs to good products, and each step is performed precisely, and the process is extremely complicated and takes a long time.
The mass spectrometry technology has the characteristics of high analysis speed, strong specificity and high sensitivity. In recent years, with the continuous innovation and improvement of mass ionization technology and mass analyzers, mass spectrometry technology exhibits excellent qualitative and quantitative capabilities at the molecular level.
However, the traditional detection method for the nutrient substance change process in the traditional Chinese medicine sample mainly comprises the steps of carrying out pretreatment such as crushing, grinding, centrifuging, purifying and the like on the traditional Chinese medicine to obtain target analytes with complex matrixes removed, and then carrying out mass spectrometry. These processes are cumbersome and time consuming and the process of treatment with chemicals may result in loss of samples, contamination, degradation or initiation of biological stress, resulting in low analysis efficiency and poor reliability.
Disclosure of Invention
Based on the above, the utility model aims to provide a sample processing device for mass spectrometry detection, which aims to solve the problems that the excessive pretreatment process is tedious and time-consuming and the sample to be detected is lost and polluted when the effective components of the Chinese herbal medicine fructus aurantii are detected in the prior art.
The utility model provides a sample processing device for mass spectrometry detection, which comprises a sampling assembly and an extraction assembly arranged below the sampling assembly, wherein the extraction assembly comprises a shielding outer sleeve and an extraction needle arranged in the shielding outer sleeve, the extraction needle comprises a connecting block, an extraction vertical pipe arranged above the connecting block and an extraction horizontal pipe arranged on the side surface of the connecting block, the extraction vertical pipe is communicated with the extraction horizontal pipe, the shielding outer sleeve is provided with a through hole matched with the extraction horizontal pipe, the sampling assembly comprises a sealing cover sleeved outside the shielding outer sleeve, a compression bar arranged on the sealing cover and a liquid leakage quantitative pipe arranged under the sealing cover, the liquid leakage quantitative pipe is sleeved outside the connecting block and provided with a cutting inclined plane at the bottom, a filtering hole is arranged on the side wall of the liquid leakage quantitative pipe, an ionization needle is arranged at the bottom of the connecting block, a filter plate is sleeved outside the connecting block so that the ionization needle and the extraction needle are separated into two spaces, and a liquid collecting cylinder for collecting filtered solution is arranged at the bottom of the filter plate.
Above-mentioned a sample processing device for mass spectrometry detects, it can be understood, carry out direct sample to the bitter orange through sampling subassembly, the rethread extraction subassembly carries out extraction to the sample to through ionization needle and external pressure equipment make the solution ionization atomizing after the extraction, solution after the atomizing gets into the mass spectrometer and detects, and then can accomplish the sample and the preliminary treatment step of bitter orange through a device, detection efficiency has been accelerated greatly, loaded down with trivial details preliminary treatment process is replaced by the electric extraction and has further accelerated detection efficiency in addition, and avoided too much preliminary treatment to bring the problem of sample loss pollution. When the device is specifically used, an operator holds the pressing rod by hand to align the bottom of the liquid leakage quantitative tube with the fructus aurantii, fixes the fructus aurantii, applies force to the pressing rod and presses down, cuts the fructus aurantii through the cutting inclined plane, so that the central part of the fructus aurantii is arranged in the liquid leakage quantitative tube, then the sampling assembly is sleeved on the extraction assembly, the extraction liquid is injected into the extraction assembly through the through hole, the extraction liquid enters the liquid leakage quantitative tube through the extraction transverse tube and the extraction vertical tube to soak the sample, the sampling and extraction of the fructus aurantii sample are realized, the extracted solution enters the liquid collecting tube through the filter plate, is ionized under the action of the ionization needle, is ionized and atomized under the action of external pressure supply equipment, and is sprayed to the mass spectrometer through the ionization needle for detection. The utility model solves the problems that the excessive pretreatment process is tedious and time-consuming and causes loss and pollution to the sample to be tested when the effective components of the Chinese herbal medicine fructus aurantii are detected in the prior art.
In addition, the sample processing device for mass spectrometry detection provided by the utility model can also have the following additional technical characteristics:
preferably, the plurality of filtering holes are uniformly distributed on the side wall of the leakage quantitative pipe so that the inner side of the leakage quantitative pipe is communicated with the inner cavity of the shielding outer sleeve.
Preferably, a plurality of uniformly equidistantly distributed filter holes are formed in the filter plate, and the outer side of the filter plate is abutted to the inner wall of the shielding outer sleeve.
Preferably, the bottom of the liquid collecting cylinder is conical, the top of the liquid collecting cylinder is abutted against the bottom of the filter plate, and the side surface of the liquid collecting cylinder is abutted against the inner wall of the shielding outer sleeve.
Preferably, the bottom of the shielding outer sleeve is provided with an avoidance groove matched with the ionization needle, and one end, far away from the connecting block, of the ionization needle penetrates through the liquid collecting cylinder to be placed in the avoidance groove.
Preferably, the ionization needle is of a hollow structure, and a liquid inlet hole is formed in the side wall, close to one end of the connecting block, of the ionization needle, so that the ionization needle is communicated with the inner cavity of the liquid collecting cylinder.
Preferably, the filter plate and the liquid collecting cylinder are provided with a transverse groove for avoiding the extraction transverse tube.
Preferably, a sealing groove is formed in the top of the shielding outer sleeve, and a sealing ring is arranged in the sealing groove.
Preferably, the side wall of the shielding outer sleeve, which is close to one end of the sealing cover, is provided with external threads, and the inner wall of the sealing cover is provided with internal threads which are matched with the external threads.
Preferably, the outer side wall of the leakage quantifying pipe far away from one end of the cutting inclined plane is provided with an external thread, and the bottom of the sealing cover is provided with a screw hole matched with the external thread.
Drawings
FIG. 1 is a schematic diagram of a sample processing device for mass spectrometry detection according to an embodiment of the present utility model;
FIG. 2 is an exploded view of a sample processing device for mass spectrometry detection according to one embodiment of the present utility model;
FIG. 3 is a view from another perspective of FIG. 2;
FIG. 4 is a schematic cross-sectional view of a sample processing device for mass spectrometry detection according to an embodiment of the present utility model;
description of main reference numerals:
the utility model will be further described in the following detailed description in conjunction with the above-described figures.
Detailed Description
In order that the utility model may be readily understood, a more complete description of the utility model will be rendered by reference to the appended drawings. Several embodiments of the utility model are presented in the figures. This utility model may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
It will be understood that when an element is referred to as being "mounted" on another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like are used herein for illustrative purposes only.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this utility model belongs. The terminology used herein in the description of the utility model is for the purpose of describing particular embodiments only and is not intended to be limiting of the utility model. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
Referring to fig. 1 to 4, a sample processing device for mass spectrometry detection according to an embodiment of the present utility model includes a sampling assembly 10 and an extraction assembly disposed below the sampling assembly 10, wherein:
the extraction subassembly 20 includes shielding outer tube 21, set up the extraction needle 22 in shielding outer tube 21, extraction needle 22 includes connecting block 221, set up the extraction standpipe 222 in connecting block 221 top, and set up the extraction violently pipe 223 in the connecting block 221 side, extraction standpipe 222 and extraction violently pipe 223 intercommunication, shielding outer tube 21 is equipped with the through-hole 211 with the adaptation of extraction violently pipe 223, sampling assembly 10 is including the sealed lid 11 of cover setting in shielding outer tube 21 outside, the depression bar 12 of setting on sealed lid 11 and the weeping ration pipe 13 of setting under sealed lid 11, weeping ration pipe 13 cover is established in the connecting block 221 outside and the bottom is equipped with cutting inclined plane 131, be equipped with filtration pore 132 on the weeping ration pipe 13 lateral wall.
It can be understood that the sampling component 10 is used for directly sampling the fructus Aurantii, the extraction component 20 is used for extracting the sample, the ionization needle 25 and the external pressure supply device 40 are used for ionizing and atomizing the extracted solution, the atomized solution enters the mass spectrometer for detection, and then the sampling and pretreatment steps of the fructus Aurantii can be completed through one device, so that the detection efficiency is greatly improved, in addition, the complicated pretreatment process is replaced by electric extraction to further improve the detection efficiency, and the problem of sample loss and pollution caused by excessive pretreatment is avoided. When the device is specifically used, an operator holds the pressure lever 12 to align the bottom of the liquid leakage quantitative tube 13 with the fructus aurantii, fixes the fructus aurantii, applies force to the pressure lever and presses down, cuts the fructus aurantii through the cutting inclined plane 131, so that the central part of the fructus aurantii is placed in the liquid leakage quantitative tube 13, then the sampling assembly 10 is sleeved on the extraction assembly 20, then the extraction liquid is injected into the extraction assembly 20 through the through hole 211, the extraction liquid enters the liquid leakage quantitative tube 13 through the extraction transverse tube 223 and the extraction vertical tube 222 to soak the sample, further the sampling and extraction of the fructus aurantii sample are realized, the extracted solution enters the liquid collecting cylinder 24 through the filter plate 23, is ionized under the action of the ionization needle 25, and is ionized and atomized under the action of the external pressure supply device 40, and is sprayed to the mass spectrometer for detection through the ionization needle 25. The utility model solves the problems that the excessive pretreatment process is tedious and time-consuming and causes loss and pollution to the sample to be tested when the effective components of the Chinese herbal medicine fructus aurantii are detected in the prior art.
When the extraction liquid is introduced for extraction, the introduced extraction liquid is charged extraction liquid under preset extraction voltage, charged particles in a detection sample are enabled to generate directional motion in the extraction liquid under the action of a direct current electric field according to a similar compatibility principle and an electric field effect, the component proportions of the extraction liquid are different, so that the dissociation degree of sample molecules is different, the migration speed of the sample molecules is also different, the substrate separation and the enrichment effect of an object to be detected are realized, the enrichment effect can be effectively improved, the electric extraction effect of the fructus aurantii is further accelerated, and the rapid detection function is realized. In addition, the leakage quantitative tube 13 belongs to one of quantitative tubes, and the quantitative tube is accurately weighed by a precise balance through a large number of samples in the early stage, then the size of the quantitative tube is determined, and further, in the actual operation, the quantitative tubes with different sizes are selected, so that the sample amount in the sampling process can be determined. Therefore, before the device is used for electric extraction, a leakage quantitative tube 13 with proper specification is needed to quantitatively sample a sample, so as to determine the content of a substance to be detected in the sampled sample during the subsequent mass spectrum detection.
In addition, a plurality of evenly distributed filtering holes 132 are arranged on the side wall of the leakage quantitative tube 13, so that the inner side of the leakage quantitative tube 13 is communicated with the inner cavity of the shielding outer sleeve 21. Through setting up the filtration pore 132 and making the extract can flow into in the shielding outer tube 21, through the sealing connection of shielding outer tube 21 and sealed lid 11 for the device is inside sealed, so that the extract carries out the extraction, and in addition the bitter orange sample is then isolated by weeping ration pipe 13, so that collect the extract after the extraction and carry out mass spectrum detection.
By way of example and not limitation, in some alternative embodiments, the filter plate 23 is sleeved outside the connection block 221, and a plurality of uniformly distributed filter holes 231 are formed on the filter plate 23, and the outer side of the filter plate 23 is abutted against the inner wall of the shielding outer sleeve 21. Further, a liquid collecting cylinder 24 is arranged below the connecting block 221, the bottom of the liquid collecting cylinder 24 is conical, the top of the liquid collecting cylinder 24 is abutted against the bottom of the filter plate 23, and the side surface of the liquid collecting cylinder 24 is abutted against the inner wall of the shielding outer sleeve 21. The extracted extract is subjected to secondary filtration treatment through the filter plate 23 and the filter holes 231 on the filter plate 23, so that the detection accuracy is improved, and the extract is collected in a concentrated manner through the liquid collecting cylinder 24 with the conical bottom. The side surfaces of the filter plate 23 and the liquid collecting cylinder 24 are abutted against and sealed with the inner cavity of the shielding outer sleeve 21, so that the extraction liquid is prevented from flowing out of a gap between the filter plate and the liquid collecting cylinder.
Further, an ionization needle 25 is arranged at the bottom of the connecting block 221, an avoidance groove 212 matched with the ionization needle 25 is arranged at the bottom of the shielding outer sleeve 21, and one end, far away from the connecting block 221, of the ionization needle 25 penetrates through the liquid collecting cylinder 24 and is arranged in the avoidance groove 212. And, the ionization needle 25 is hollow, and the side wall of the ionization needle 25 near one end of the connecting block 221 is provided with a liquid inlet 251, so that the ionization needle 25 is communicated with the inner cavity of the liquid collecting cylinder 24. Specifically, through setting up ionization needle 25 and making external equipment pass through dodge the groove and be connected electrically conductive with ionization needle 25, and then make ionization needle 25 carry out ionization to the extract in the liquid collection tube 24 to apply pressure to shielding outer tube 21 inner chamber through-hole 211 through outside high-pressure device, make the extract ionization atomize and pass through feed liquor hole 251 and follow hollow ionization needle 25 syringe needle blowout and get into mass spectrum check out test set and carry out mass spectrum and detect. In addition, because the electric extraction efficiency is high, a good extraction effect can be achieved by only a small amount of extraction liquid, and because the amount of extraction liquid is small, the ionization needle 25 only needs to be partially arranged in the liquid collecting cylinder 24 for ionization, and the ionization needle does not need to be fully arranged in the liquid collecting cylinder 24. In addition, when the electric extraction is performed, too much extraction liquid can affect the movement of charged ions in an electric field, so that the extraction is the best choice of the electric extraction by adopting a small amount of extraction liquid.
Specifically, the filter plate 23 and the liquid collecting cylinder 24 are provided with a transverse groove 232 for avoiding the extraction transverse tube 223. By providing the transverse grooves 232, the filter plate 23 and the liquid collecting cylinder 24 are conveniently and fixedly assembled on the extraction needle 22.
In addition, a sealing groove 213 is formed in the top of the shielding outer sleeve 21, and a sealing ring 30 is arranged in the sealing groove 213. Through setting up seal groove 213 and sealing washer 30 for shielding outer tube 21 inside is sealed, and then makes can make the extraction liquid atomizing through external pressure equipment 40, and then the extraction liquid of atomizing can follow ionization needle 25 syringe needle blowout and carry out mass spectrum detection.
Specifically, the side wall of the shielding outer sleeve 21, which is close to one end of the sealing cover 11, is provided with external threads, and the inner wall of the sealing cover 11 is provided with internal threads which are matched with the external threads. The sealing cover 11 is fixed on the shielding outer sleeve 21 in a threaded connection mode, if proper conical threads are adopted, the sealing effect can be achieved, and in addition, the sealing ring 30 is screwed to fill the sealing groove 213 so as to ensure the sealing effect in the shielding outer sleeve 21.
In addition, the outer side wall of one end of the leakage metering tube 13, which is far away from the cutting inclined plane 131, is provided with an external thread, and the bottom of the sealing cover 11 is provided with a screw hole 111 which is matched with the external thread. The leakage quantitative pipe 13 and the sealing cover 11 are detachably connected, so that the disposable leakage quantitative pipe 13 can be used, further, the cleaning of samples on the inner wall of the leakage quantitative pipe 13 is avoided, and the detection efficiency is quickened.
In summary, in the sample processing device for mass spectrometry detection according to the above embodiment of the present utility model, the sampling component 10 is used for directly sampling the fructus Aurantii, the extraction component 20 is used for extracting the sample, and then the sampling and pretreatment steps of the fructus Aurantii can be completed by one device, so that the detection efficiency is greatly improved, and in addition, the complicated pretreatment process is replaced by the electric extraction to further improve the detection efficiency, and the problem of sample loss and pollution caused by excessive pretreatment is avoided. When the device is specifically used, an operator holds the pressure lever 12 to align the bottom of the liquid leakage quantitative tube 13 with the fructus Aurantii, fixes the fructus Aurantii, applies force to the pressure lever 12 to press down, cuts the fructus Aurantii through the cutting inclined plane 131, places the central part of the fructus Aurantii in the liquid leakage quantitative tube 13, then sleeves the sampling assembly 10 on the extraction assembly 20, injects the extraction liquid into the extraction assembly 20 through the through hole 211, and the extraction liquid enters the liquid leakage quantitative tube 13 through the extraction transverse tube 223 and the extraction vertical tube 222 to soak the sample, thereby realizing the sampling and extraction of the fructus Aurantii sample. The utility model solves the problems that the excessive pretreatment process is tedious and time-consuming and causes loss and pollution to the sample to be tested when the effective components of the Chinese herbal medicine fructus aurantii are detected in the prior art.
In the description of the present specification, a description referring to terms "one embodiment," "some embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present utility model. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiments or examples. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The foregoing examples illustrate only a few embodiments of the utility model and are described in detail herein without thereby limiting the scope of the utility model. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the utility model, which are all within the scope of the utility model. Accordingly, the scope of protection of the present utility model is to be determined by the appended claims.
Claims (10)
1. The utility model provides a sample processing device for mass spectrometry detects, its characterized in that is in including sampling subassembly and setting the extraction subassembly of sampling subassembly below, the extraction subassembly includes shielding outer tube, sets up extraction needle in the shielding outer tube, the extraction needle includes the connecting block, sets up extraction standpipe above the connecting block and set up the extraction cross tube of connecting block side, extraction standpipe with extraction cross tube intercommunication, the shielding outer tube be equipped with the through-hole of extraction cross tube adaptation, the sampling subassembly is including the cover of cover outside of shielding outer tube establish sealing lid, setting up depression bar on the sealing lid and set up leak liquid quantitative pipe under the sealing lid, leak liquid quantitative pipe cover is established the connecting block outside and the bottom is equipped with the cutting inclined plane, be equipped with the filtration pore on the leak liquid quantitative pipe lateral wall, the connecting block bottom is equipped with the ionization needle, the cover is equipped with the filter in the connecting block outside, so that the ionization needle with the extraction needle separates in two spaces, the filter bottom is equipped with the section of thick bamboo that is used for collecting the solution after filtering.
2. The sample processing device for mass spectrometry detection of claim 1, wherein a plurality of said filter holes are uniformly distributed on the side wall of said leak-off quantitative tube such that the inside of said leak-off quantitative tube communicates with the inner cavity of said shielded outer sleeve.
3. The sample processing device for mass spectrometry detection according to claim 1, wherein a plurality of uniformly equidistantly distributed filter holes are formed in the filter plate, and the outer side of the filter plate is abutted against the inner wall of the shielding outer sleeve.
4. A sample processing device for mass spectrometry detection according to claim 3, wherein the bottom of the collector is tapered, the top of the collector abuts the bottom of the filter plate, and the sides of the collector abut the inner wall of the shielded outer sleeve.
5. The sample processing device for mass spectrometry detection according to claim 4, wherein an avoidance groove matched with the ionization needle is formed in the bottom of the shielding outer sleeve, and one end, away from the connecting block, of the ionization needle penetrates through the liquid collecting cylinder and is arranged in the avoidance groove.
6. The sample processing device for mass spectrometry detection according to claim 5, wherein the ionization needle is hollow, and a liquid inlet is formed in a side wall of the ionization needle near one end of the connecting block, so that the ionization needle is communicated with the inner cavity of the liquid collecting cylinder.
7. The sample processing device for mass spectrometry detection according to claim 4, wherein the filter plate and the liquid collecting cylinder are provided with a transverse groove for avoiding the extraction transverse tube.
8. The sample processing device for mass spectrometry detection according to any one of claims 1 to 7, wherein a sealing groove is arranged at the top of the shielding outer sleeve, and a sealing ring is arranged in the sealing groove.
9. The sample processing device for mass spectrometry detection according to claim 8, wherein the side wall of the shielding outer sleeve, which is close to one end of the sealing cover, is provided with external threads, and the inner wall of the sealing cover is provided with internal threads which are matched with the external threads.
10. The sample processing device for mass spectrometry detection according to claim 8, wherein an external thread is arranged on the outer side wall of one end of the liquid leakage quantifying tube, which is far away from the cutting inclined plane, and a screw hole which is matched with the external thread is arranged at the bottom of the sealing cover.
Priority Applications (1)
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CN202322349836.XU CN219870574U (en) | 2023-08-31 | 2023-08-31 | Sample processing device for mass spectrometry detection |
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CN202322349836.XU CN219870574U (en) | 2023-08-31 | 2023-08-31 | Sample processing device for mass spectrometry detection |
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CN219870574U true CN219870574U (en) | 2023-10-20 |
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CN202322349836.XU Active CN219870574U (en) | 2023-08-31 | 2023-08-31 | Sample processing device for mass spectrometry detection |
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